Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:2.3.1.107 (DAT)
 1,471 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The intra uterine ponderal index (IPI) estimated by ultrasound examination (US) in 79 patients with intrauterine growth retardation (IUGR) is presented. The IPI was calculated using the following formula: [formula: see text] 13.2 (DFO) + 22 (DAT) + 8.9 (DAP) - 48.4 (LF) - 7469.1, and ETF = 0.55 (LF) + 8.66. Correlation indexes (r) of EPF, ETF and IPI with neonatal weight, length and ponderal index were 0.92, 0.87 and 0.51 (p < 0.001). The IPI revealed a gradual increase with respect to gestational age ranging from 1.63 to 3.08. The p 10 of the IPI was 1.96 for pregnancies of 30 to 34 weeks and 2.35 for pregnancies of 35 to 39 weeks. Those cases of IUGR with IPI < p 10 (n = 7) had a higher incidence of cesarean section (86% vs 30%, p < 0.01), intrapartum fetal distress (71% vs 11%, p < 0.01), Apgar score of < 7 at 5' (29% vs 1.4%, p < 0.05), PBF < 5 points (43% vs 4.7%, p < 0.01), and moderate or severe neonatal morbidity (57% vs 21%, p < 0.05) than those with IPI > or = p 10 (n = 72). No difference were found with respect to the presence of antepartum meconium (29% vs 6%, p = 0.09). In conclusion, ultrasonographic estimation of the IPI is another element of the examination that can help in the diagnosis of fetal condition in cases of IUGR, permitting to distinguish those fetuses that, having and estimated weight below the tenth percentile in a growth curve, are in higher perinatal risk.
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PMID:[Intrauterine weight index in fetal growth retardation]. 184 19

Impacts of floods on human society have been drawing increasing human concerns in recent years. In this study, flood observations from EM-DAT (Emergency Events Database) and DFO (Dartmouth Flood Observatory) datasets were analyzed to investigate frequency and intensity of floods, and flood-induced mortality, flood-affected population as well during 1975-2016 across the globe. Results indicated that: (1) occurrence rate of floods, flood-induced mortality and flood-affected population were generally increasing globally. However, flood-induced mortality and flood-affected people per flood event were in slight decrease, indicating that flood-induced mortality and flood-affected people due to increased floods exceeded those by individual flood event; (2) annual variation of mortality per flood event is highly related to floods with higher intensity. Specifically, the flood frequency and flood-induced mortality are the largest in Asia, specifically in China, India, Indonesia and Philippine; while significantly increased flood-affected population and mean annual mortality was detected in China, USA and Australia; (3) tropical cyclones (TC) are closely related to flood-induced mortality in parts of the countries along the western coast of the oceans. The frequency of channel floods in these regions is the largest and large proportion of flood-induced deaths and the highest flood-induced mortality can be attributed to TC-induced flash floods; (4) Population density and GDP per unit area are in significantly positive correlation with the number of flood-related victims per unit area, number of deaths and economic losses with exception of low-income countries. However, the flood-affected population and flood-induced mortality increase with decrease of per capita GDP; while the per capita economic loss increases with the increase of per capita GDP, indicating that the higher the population density and GDP per unit for a region, the higher sensitivity of this area to flood hazards.
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PMID:Flood-induced mortality across the globe: Spatiotemporal pattern and influencing factors. 2993 60