Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:2.3.1.107 (DAT)
 1,471 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Thirty-five patients with organic dementia were investigated with multichannel FFT analysis of EEG. In 21 of them, somatosensory-evoked potentials (SEPs) with stimulation of the median nerves were also recorded. Based on clinical and psychometric data and regional cerebral blood flow measurements, the patients were subdivided into Alzheimer-type dementia (DAT) of moderate (n = 10) and severe (n = 11) degree, multi-infarct dementia (MID) (n = 7), and frontotemporal degeneration (FTD) (n = 7). The FTD patients showed mild EEG abnormality and the MID patients showed increases of low frequency activity in combination with a well-preserved posterior dominant activity. The DAT patients showed the most pronounced abnormalities with deterioration of the posterior activity combined with a large increase of low frequency activity. The SEPs of the DAT group showed an amplitude enhancement of the parietal response components. The FTD group showed only a moderate delay of the precentral N30 component. The MID group showed individually varying abnormalities, including a delay of the primary cortical response. It is concluded that the different distributions of pathology in the different organic dementia disorders are reflected in the quantified EEG and SEPs as studied with multichannel technique.
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PMID:Multichannel EEG frequency analysis and somatosensory-evoked potentials in patients with different types of organic dementia. 835 5

Performance at eight cognitive tests and EEG spectral power at rest was computed in 2 groups of men and women, between 17 and 21 years of age, with extreme degrees of spatial ability (SA) evaluated by the spatial relations subtest of the DAT: a low spatial ability group (10 men, 10 women) with scores below percentile 30 and a high spatial ability group (10 men, 10 women) with scores above percentile 80. Ten EEG artifact free samples, 4.096 sec each, were analyzed and absolute (AP) and relative power (RP) were obtained for 5 frequency bands using an FFT. EEG was submitted to principal component analysis and two way ANOVAs. High SA showed lower AP in the entire spectrum with eyes open and closed, and lower alpha 1 RP with eyes open than low SA group regardless of sex. The difference between low and high SA was better explained by high alpha AP at all derivations and high theta AP at right derivations and at left central and occipital regions. Women showed higher beta 1 and beta 2 AP at all derivations except at temporal regions than men regardless of SA scores.
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PMID:Effect of spatial ability and sex on EEG power in high school students. 854 80