Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.3.1.107 (
DAT
)
1,471
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The relationship between
anosognosia
of memory deficit, intrusions and 'frontal' functions was investigated in 12 Alzheimer (
DAT
) patients, 12 depressed patients and 24 normal controls.
DAT
and depressed patients could not be dissociated according to the proportion of intrusion they produced in memory tasks. However, regardless of their clinical diagnosis, patients with
anosognosia
produced significantly more intrusions than patients without
anosognosia
, and
anosognosia
of memory deficit was positively and strongly correlated to the tendency to produce intrusions. By contrast, there was no correlation between intrusions,
anosognosia
and patients' performance on frontal tasks except for Verbal Fluency. Whereas
anosognosia
of memory deficit seems indispensable for intrusions, frontal dysfunction must not be considered a necessary condition for intrusions or
anosognosia
.
...
PMID:Anosognosia, intrusions and 'frontal' functions in Alzheimer's disease and depression. 774 67