Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.3.1.107 (
DAT
)
1,471
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A complicated form of
spastic paraplegia
is a neurodegenerative disorder presenting as progressive spasticity in the bilateral lower limbs accompanied by some clinical features. The present case showed spastic paralysis and hyperreflexia in all extremities as well as lead pipe rigidity in the neck and bilateral upper extremities (R < L), decreased scores on frontal cognitive tests, a decreased accumulation of the right dorsal putamen on a
DAT
scan, and hypoperfusion of the bilateral frontal lobes on
99m
Tc-ECD single photon emission computed tomography (SPECT). The present case provides a new spectrum of
spastic paraplegia
based on the evidence of clinical scores and the findings of brain functional imaging.
...
PMID:Spastic Paraplegia Accompanied by Extrapyramidal Sign and Frontal Cognitive Dysfunction. 3129 81
