Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:2.1.1.69 (BMT)
 2,655 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

To study the potentialities of MR tomography in the diagnosis of chromaffin tissue tumors and to elaborate a number of quantitative diagnostic criteria, 26 patients with pheochromocytoma were examined. All the patients were subjected to x-ray computer-aided tomography of the adrenals. In 24 of them, the diagnosis was completely confirmed on histological examination of the excised tumor. The control group consisted of 19 healthy persons. All the investigations were performed on a MR tomograph BMT-1100 manufactured by Brucker Company (FRG) (0.235 T) according to the SE technique, with TR being 2 s and TE 34 ms. The visual picture together with a number of quantitative parameters (the time of spin-spin relaxation--T2, the index of relative signal intensity) were appraised. The method is shown to be highly informative in the diagnosis of pheochromocytomas, particularly of extra-adrenal site. In addition to a more prolonged T2, the high values of the index of relative signal intensity appeared very suggestive, especially on the 3d and 4th echo images.
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PMID:[The diagnosis of tumors of the chromaffin tissue by magnetic resonance tomography]. 262 52

MR-tomography was used for the investigation of 38 healthy persons aged 17 to 48 with normal BP values without any renal and adrenal pathology (kidneys were investigated in 25 persons, adrenal glands--in 16). A BMT-1100 MR-tomograph (Brucker, FRG) was used for investigation. The authors stress noninvasiveness of the new method and its practical value. It permits the differentiation of the cortical and medullary substance of the kidney and in some cases of the adrenal glands. It also permits the evaluation of their shape, size and position. The authors also showed a possibility of assessing the status of these organs using some quantitative parameters. Due to its safety, high resolution and good imaging the method holds great promise.
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PMID:[Magnetic resonance tomography of the kidney and adrenal glands in normal subjects]. 279 40

99 patients with arterial hypertension (AH) were studied: 17 patients with pheochromocytoma, 37 with aldosteronoma, 4 with corticosteroma, 38 with essential hypertension. Control group included 16 healthy subjects. The investigation was performed by means of a NMR-tomograph BMT-1100 ("Brucker", FRG) in axial and frontal planes according to Spin Echo (SE) technique with TR = 2.0 s, TE = 34 ms. Qualitative (visual) as well as quantitative criteria for evaluation of adrenal glands state were developed. Normal size of adrenal glands, relative intensity of their signal and T2 were calculated. The data obtained proved that relative intensity of the signal is a highly informative parameter for differential diagnosis of adrenal gland tumors (its value of less than 1.0 is evidence of cortex lesion, and that of more than 1.4--of medulla lesion). High informative value of MR-tomography for evaluation of adrenal glands state in patients with AH is proved by comparative data obtained by other methods, such as computer tomography aortography and histomorphology.
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PMID:[Clinical use of magnetic resonance tomography for assessing adrenal function in patients with arterial hypertension]. 285 44

Linear dimensions of hearts in 16 healthy volunteers obtained by magnetic resonance tomography (MRT) and 2-dimensional echocardiography (EchoKG) were compared. MRT was performed with BMT 1100 tomograph ("Bruker", FRG) with magnetic field strength of 0.235 T using EKG-triggering. Oblique slices through anatomic heart axes were registered. Good correspondence of MRT- and EchoKG-obtained linear dimensions of heart structures (r = 0.62-0.85) prove that MRT allows evaluation of dimensions of various heart structures as effectively as 2-dimensional EchoKG.
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PMID:[Determining the linear dimensions of the heart in healthy persons by the method of magnetic resonance tomography]. 340 34

Thirty seven patients with arterial hypertension of renal genesis (chronic diffuse glomerulonephritis, chronic pyelonephritis, renal cystic disease and congenital abnormalities) were subjected to NMR-tomography. The comparison group comprised 12 patients with essential hypertension and 18 normal individuals constituted the control group. The examination was effected in the axial, frontal and sagittal planes using the BMT-1100 NMR-tomograph (Brucker, FRG) with the magnetic intensity of 0.235 T, the coil diameter of 60 cm, and the working frequency of 9.95 MHz. The technique made it possible to draw conclusions as to the presence or absence of the kidneys, their form, size, location and the structure of their cortex and medulla. The anatomo-tomographic picture of the kidneys in patients with chronic diffuse glomerulonephritis without renal insufficiency resembled that in cases of essential hypertension. In patients with chronic pyelonephritis the kidney contour was uneven and when renal insufficiency was present the kidneys were small and the borderline the cortex and the medulla was poorly differentiated. The technique proved especially informative in renal cystic disease and congenital abnormalities (renal aplasia and hypoplasia). The results obtained were compared with the data provided by other examination techniques.
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PMID:[Diagnostic potentials of NMR tomography of the kidneys of patients with symptomatic renal hypertension]. 406 86