Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.1.1.67 (thiopurine methyltransferase)
 551 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
thiopurine S-methyltransferase 0.484
thiopurine methyltransferase 0.355
NUDT15 0.037
DPYD 0.003
TGN 0.003
glucosamine-6-phosphate deaminase 1 0.002
ITPA 0.002
RASGRP4 0.002
PACSIN2 0.001
SLCO1B1 0.001
VKORC1 0.001
SLC16A5 0.001
UGT1A1 0.001
inosine triphosphatase 0.001
dihydropyrimidine dehydrogenase 0.001
CYP2C9 0.001
BEC1 0.001
INPP1 0.001
solute carrier family 19 member 1 0.001
otospiralin 0.001
CYP2C19 0.001
ACYP2 0.001
AOF1 0.001
MT1L 0.001
HLAB 0.001
CYP2D6 0.000
SLC19A1 0.000
GlcNAc6ST-3 0.000
catechol O-methyltransferase 0.000
CYP3A5 0.000
MT1H 0.000
TRIM46 0.000
COMT 0.000
ITPase 0.000
MTHFR 0.000
molybdenum cofactor sulfurase 0.000
equilibrative nucleoside transporter 2 0.000
BEC2 0.000
KIF6 0.000
GST-5 0.000
CHST6 0.000
CBR3 0.000
allele c 0.000
NAT2 0.000
SLC28A3 0.000
NTP 0.000
ABCC3 0.000
SLC15A2 0.000
SEMA3C 0.000
cytochrome P4502D6 0.000
histamine N-methyltransferase 0.000
KIF13A 0.000
NUP153 0.000
PGAM1 0.000
TNFAIP2 0.000
ABCC4 0.000
SLCO1A2 0.000
MT1X 0.000
DLG5 0.000
inosine monophosphate dehydrogenase 0.000
UBE2D3 0.000
TRIM59 0.000
CYP4F3 0.000
SAM-dependent methyltransferase 0.000
SLC22A2 0.000
FLT3 receptor tyrosine kinase 0.000
KPNB1 0.000
ANXA3 0.000
CYP2A7 0.000
TYMS 0.000
MAPK7 0.000
ASNS 0.000
PRDX4 0.000
cytochrome P450 3A5 0.000
NT5C2 0.000
glucuronosyltransferase 0.000
CYP2B6 0.000
GSTT2 0.000
ABCC7 0.000
CYP2F1 0.000
more...
Disease
Thiopurine methyltransferase deficiency 0.009
Functional hearing loss 0.001
myelosuppression 0.001
Xanthine oxidase deficiency 0.001
inflammatory bowel disease 0.001
childhood ALL 0.000
acute lymphoblastic leukemia 0.000
Hypersensitivity syndrome 0.000
leukopenia 0.000
Crohn's disease 0.000
pancytopenia 0.000
ulcerative colitis 0.000
XPD 0.000
Ototoxicity 0.000
hypoprothrombinemia 0.000
DPD deficiency 0.000
pompholyx 0.000
enzyme deficiency 0.000
childhood cancer 0.000
leukemia 0.000
drug-induced hepatitis 0.000
Immune thrombocytopenia 0.000
Hepatotoxicity 0.000
SBS 0.000
SBS 0.000
neutropenia 0.000
pancreatitis 0.000
pemphigus 0.000
Inflammatory Bowel Disease 0.000
CDA 0.000
hepatic veno-occlusive disease 0.000
irritable bowel syndrome 0.000
minimal residual disease 0.000
secondary AML 0.000
hepatitis 0.000
BCH 0.000
Leukemia 0.000
Medulloblastoma 0.000
ACD 0.000
Gilbert 0.000
hypertrichosis 0.000
leukemogenesis 0.000
T-cell acute lymphoblastic leukemia 0.000
drug hypersensitivity 0.000
cancer 0.000
pemphigoid 0.000
HSS 0.000
Wegener's granulomatosis 0.000
torsades de pointes 0.000
Colitis 0.000
AIN 0.000
B-ALL 0.000
esophageal varices 0.000
autoimmune hemolytic anemia 0.000
agranulocytosis 0.000
lymphoproliferative disorders 0.000
prediabetes 0.000
ABL 0.000
hematologic malignancies 0.000
lupus nephritis 0.000
systemic lupus erythematosus 0.000
drug withdrawal 0.000
idiopathic pulmonary fibrosis 0.000
EMA 0.000
rheumatoid arthritis 0.000
rash 0.000
viral diarrhea 0.000
Bordetella 0.000
autoimmune disease 0.000
PSS 0.000
PSS 0.000
colitis 0.000
myasthenia gravis 0.000
thyrotoxicosis 0.000
opportunistic infection 0.000
yellow fever 0.000
immune deficiency 0.000
lymphoblastic leukemia 0.000
acute myeloid leukemia 0.000
stomatitis 0.000
more...
Symptom
arthralgia 0.000
paresthesia 0.000
nausea and vomiting 0.000
splenomegaly 0.000
Ill 0.000
vomiting 0.000
tremor 0.000
angina 0.000
discomfort 0.000
nausea 0.000
discomfort 0.000
diarrhea 0.000
headache 0.000
seizures 0.000
pain 0.000
Drug
Mercaptopurine 0.001
Sulphasalazine 0.000
Monit 0.000
Infliximab 0.000
Infliximab 0.000
Neoral 0.000
Budesonide 0.000
TEL 0.000
Irinotecan 0.000
Prednisone 0.000
CTC 0.000
Etoposide 0.000
CTC 0.000
Tacrolimus 0.000
MRC 0.000
Glutathione 0.000
Mutagen 0.000
THF 0.000
ABC 0.000
caffeine 0.000
Dermatol 0.000
Enzyme
thiopurine methyltransferase 0.996
dihydropyrimidine dehydrogenase 0.001
dihydropyrimidine dehydrogenase 0.001
inosine triphosphatase 0.001
EC 3.6.1.19 0.001
thioether S-methyltransferase 0.001
catechol O-methyltransferase 0.000
TMT 0.000
histamine N-methyltransferase 0.000
S-adenosylhomocysteine nucleosidase 0.000
IMP dehydrogenase 0.000
nicotinamide N-methyltransferase 0.000
AFR 0.000
methylenetetrahydrofolate reductase 0.000
methylenetetrahydrofolate reductase 0.000
UDP-glucuronosyltransferase 0.000
NAT 0.000
nucleotide pyrophosphatase 0.000
MMP 0.000
CYP3A4 0.000
xanthine oxidase 0.000
nucleoside hydrolase 0.000
conjugase 0.000
thymidylate synthase 0.000
methionine adenosyltransferase 0.000
folylpolyglutamate synthetase 0.000
N-acetyltransferase 0.000
asparaginase 0.000
asparagine synthetase 0.000
phenylethanolamine N-methyltransferase 0.000
hypoxanthine-guanine phosphoribosyltransferase 0.000
SOR 0.000
P-glycoprotein 0.000
calcineurin 0.000
glutathione S-transferase 0.000
adenosine kinase 0.000
cytidine deaminase 0.000
flavin-containing monooxygenase 0.000
purine nucleoside phosphorylase 0.000
dihydrofolate reductase 0.000
paraoxonase 0.000
aldehyde dehydrogenase 0.000
aldehyde dehydrogenase 0.000
aldehyde dehydrogenase 0.000
paraoxonase 0.000
soluble epoxide hydrolase 0.000
aldehyde dehydrogenase 0.000
aldehyde dehydrogenase 0.000
cholinesterase 0.000
CPT 0.000
CPT 0.000
MDR 0.000
CPT 0.000
NQO1 0.000
glucose-6-phosphate dehydrogenase 0.000
ERK 0.000
ACE 0.000
focal adhesion kinase 0.000
DNA polymerase 0.000
lysozyme 0.000
alanine aminotransferase 0.000
acetylcholinesterase 0.000
proteasome 0.000
catalase 0.000
superoxide dismutase 0.000
Compound
Azathioprine 0.007
6-Mercaptopurine 0.003
PTMA 0.001
Dimethyl selenide 0.001
6-Thioguanine 0.001
MMPR 0.000
Acar 0.000
adenosylmethionine 0.000
ICRF-187 0.000
TCH 0.000
S-adenosylhomocysteine 0.000
Methotrexate 0.000
HEI 0.000
UDP 0.000
DEK 0.000
EAA 0.000
CDA 0.000
SN-38 0.000
uridine 0.000
methionine 0.000
Conjugated linoleic acid 0.000
Mycophenolate mofetil 0.000
methanethiol 0.000
TPD 0.000
IMP 0.000
TEL 0.000
DNA 0.000
Nodular 0.000
MTX 0.000
Clin 0.000
DCP 0.000
TTS 0.000
cinnamyl 0.000
HPP 0.000
tellurium 0.000
Prednisone 0.000
ubiquinol 0.000
DCP 0.000
DDP 0.000
ITP 0.000
GAP 0.000
UGA 0.000
Ciprofloxacin 0.000
Cyclosporine 0.000
ABL 0.000
pyrazine 0.000
benzamide 0.000
COS 0.000
CPT 0.000
VP-16 0.000
benzoic acid 0.000
CPT 0.000
Verapamil 0.000
Verapamil 0.000
Propranolol 0.000
2-mercaptoethanol 0.000
Propranolol 0.000
EDTA 0.000
Guo 0.000
MDR 0.000
homocysteine 0.000
GSSG 0.000
selenium 0.000
FK506 0.000
A 1 0.000
Yellow 0.000
BCR 0.000
Heparin 0.000
EDTA 0.000
TNF 0.000
NIDA 0.000
5-FU 0.000
2-oxoglutarate 0.000
dUTP 0.000
His 0.000
tryptophan 0.000
tryptophan 0.000
pyrene 0.000
TCA 0.000
tryptophan 0.000
more...