EC:2.1.1.67 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: EC:2.1.1.67 (thiopurine methyltransferase)
551 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
thiopurine S-methyltransferase	311
thiopurine methyltransferase	254
NUDT15	37
CYP2C9	33
CYP2D6	32
CYP2C19	30
UGT1A1	29
TGN	27
Sep	26
dihydropyrimidine dehydrogenase	23
Mol	22
cytochrome P450	19
VKORC1	18
SLCO1B1	17
HLA	16
DPYD	16
COMT	15
CYP3A5	15
MTHFR	15
NTP	14
methyltransferase	13
MDR1	13
CYP3A4	11
xanthine oxidase	11
NAT2	10
ALL	10
ITPA	10
microsomal	9
ABCB1	9
MMP	9
CYP2B6	9
calcineurin	8
tumor necrosis factor	8
CYP2A6	7
methylenetetrahydrofolate reductase	7
P-glycoprotein	7
IBD	7
xenobiotic	7
catechol O-methyltransferase	7
1A1	6
GSTM1	6
inosine triphosphatase	6
GSTP1	6
Pseudomonas	6
CYP2E1	6
glucuronosyltransferase	6
thymidylate synthase	5
inosine monophosphate dehydrogenase	5
GSTT1	5
TNF	5
XPD	5
glutathione S-transferase	5
SLC19A1	5
CYP2C8	5
P450	5
CYP1A2	4
G6PD	4
CYP1A1	4
ABCC4	4
GST	4
ABCG2	4
N-acetyltransferase	4
NMR	4
EGFR	4
ATP	4
UGT	4
glucocorticoid receptor	4
PACSIN2	4
ABCC3	4
cytochrome P450 2D6	3
histamine N-methyltransferase	3
KRAS	3
CARD15	3
cytochrome P-450	3
HER2	3
PTEN	3
vitamin K epoxide reductase	3
CYP	3
ATP-binding cassette	3
NOD2	3

Disease
inflammatory bowel disease	88
acute lymphoblastic leukemia	74
cancer	56
myelosuppression	51
Crohn's disease	48
leukemia	45
leukopenia	30
ulcerative colitis	27
childhood ALL	25
tumor	16
pancytopenia	15
neutropenia	13
hepatitis	12
pancreatitis	12
childhood cancer	9
systemic lupus erythematosus	8
Leukemia	8
rheumatoid arthritis	8
lymphoma	7
irritable bowel syndrome	7
pemphigus	5
enzyme deficiency	5
autoimmune disease	5
XPD	5
minimal residual disease	5
Thiopurine methyltransferase deficiency	5
acute myeloid leukemia	5
rash	4
depression	4
cirrhosis	4
thrombocytopenia	4
breast cancer	4
colitis	4
multiple sclerosis	3
hypertension	3
hematologic malignancies	3
leukemogenesis	3
myasthenia gravis	2
hypoprothrombinemia	2
sepsis	2
influenza	2
esophageal varices	2
ACD	2
atopic dermatitis	2
virus infection	2
Bordetella	2
anemia	2
portal hypertension	2
Hepatotoxicity	2
acute leukemia	2
stomatitis	2
lupus nephritis	2
pemphigoid	2
vasculitis	2
PSS	2
cytomegalovirus	2
confusion	2
idiopathic pulmonary fibrosis	2
Gilbert	2
Ototoxicity	2
lymphoproliferative disorders	2
Wegener's granulomatosis	2
T-cell acute lymphoblastic leukemia	2
ABL	2
Colitis	2
Best	2
melanoma	2
CDA	2
agranulocytosis	2
drug hypersensitivity	1
lupus	1
psoriasis	1
pertussis	1
type 2 diabetes	1
skin cancer	1
Immune thrombocytopenia	1
non-small cell lung cancer	1
GSH	1
medulloblastoma	1
BCH	1

Enzyme
thiopurine methyltransferase	551
dihydropyrimidine dehydrogenase	23
dihydropyrimidine dehydrogenase	17
CYP3A4	11
xanthine oxidase	11
TMT	10
UDP-glucuronosyltransferase	10
glutathione S-transferase	9
catechol O-methyltransferase	9
MMP	9
methylenetetrahydrofolate reductase	8
calcineurin	8
methylenetetrahydrofolate reductase	8
P-glycoprotein	7
IMP dehydrogenase	7
ERK	6
thymidylate synthase	6
inosine triphosphatase	6
asparaginase	4
N-acetyltransferase	4
focal adhesion kinase	3
hypoxanthine-guanine phosphoribosyltransferase	3
NAT	3
histamine N-methyltransferase	3
cholinesterase	3
dihydrofolate reductase	3
aldehyde dehydrogenase	2
aldehyde dehydrogenase	2
aldehyde dehydrogenase	2
methionine adenosyltransferase	2
nucleotide pyrophosphatase	2
aldehyde dehydrogenase	2
aldehyde dehydrogenase	2
ACE	2
SOR	1
proteasome	1
asparagine synthetase	1
purine nucleoside phosphorylase	1
thioether S-methyltransferase	1
lysozyme	1
cytidine deaminase	1
CPT	1
conjugase	1
nucleoside hydrolase	1
acetylcholinesterase	1
paraoxonase	1
CPT	1
S-adenosylhomocysteine nucleosidase	1
phenylethanolamine N-methyltransferase	1
soluble epoxide hydrolase	1
glucose-6-phosphate dehydrogenase	1
CPT	1
superoxide dismutase	1
EC 3.6.1.19	1
adenosine kinase	1
alanine aminotransferase	1
MDR	1
paraoxonase	1
AFR	1
nicotinamide N-methyltransferase	1
DNA polymerase	1
catalase	1
flavin-containing monooxygenase	1
folylpolyglutamate synthetase	1
NQO1	1