Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.1.1.37 (DNA methyltransferase)
 4,983 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
Protease, serine, 3 12.6
ZBTB38 protein 12.6
DNA methyltransferase 12.6
GRG3 12.6
Mucin-like protocadherin 12.6
HASJ4442 12.6
N6AMT2 12.6
ZSWIM3 12.6
DNA methylase 12.6
DNMT3A protein 11.9
DNMT2 protein 11.9
Dnmt2 11.7
purinergic receptor P2RY11 11.6
attractin-like 1 11.6
Opioid binding protein/cell adhesion molecule-like 11.6
H4F2 11.6
CDK5 regulatory subunit-associated protein 1 11.6
HIST1H2AA 11.6
WD repeat and FYVE domain containing 3 11.6
DNMT2 11.5
HEMK2 11.3
DNMT3L 11.2
ATRNL1 11.1
CRBPIV 11.1
XAGE3 11.1
zinc finger protein 57 11.1
U2 small nuclear RNA auxiliary factor 1 11.1
myosin light chain kinase 3 11.1
formin homology 2 domain containing 1 11.1
Dnmt1 11.0
Dnmt3a 11.0
TRDMT1 10.9
Dnmt3b 10.8
Zinc finger protein 382 10.6
Vsm-RhoGEF 10.6
DCUN1D2 10.6
regulator of G-protein signalling 9 10.6
Dedicator of cytokinesis 1 10.6
MUPCDH 10.6
LMO6 10.6
opioid binding protein/cell adhesion molecule-like 10.6
DNMT1 10.4
NOL1 10.4
ZNF157 10.3
ZCCHC4 10.3
METTL5 10.3
C21orf127 10.3
ETNK2 10.3
Snf2-related CBP activator protein 10.3
DNMT3A 10.2
SALL4B 10.2
MET1 10.1
RFPL1 10.1
FK506-binding protein 6 10.1
JPO1 10.1
Chromodomain helicase DNA binding protein 5 10.1
methyl-CpG binding domain protein 1 10.1
Cyclin-dependent kinase inhibitor 1B 10.1
E1A-like inhibitor of differentiation 3 10.1
MBD3L2 10.1
ZNF304 10.1
Hic-1 10.1
DGKG 10.1
TMEM7 10.1
ZDBF2 10.1
COPZ2 10.1
tripartite motif-containing 28 10.1
MAP1LC3B2 10.1
DNMT3B 10.0
methyl-CpG binding domain protein 2 10.0
TNFSF7 9.9
ABCG4 gene 9.8
DHRS12 9.8
H2A.X protein 9.8
hepatocyte nuclear factor 4 gamma 9.8
POLE1 9.8
PHF20L1 9.8
IL-15RA 9.8
ubiquitin-conjugating enzyme E2A 9.8
Methylguanine-DNA methyltransferase 9.8
more...
Disease
pancreatic cancer stage 11.1
Oligoastrocytoma 11.1
Oligoastrocytoma 11.1
Diffuse pulmonary fibrosis 10.6
CIID 9.8
ovarian mixed germ cell tumor 9.5
CLAM 8.8
Cocaine withdrawal 8.7
AD7 8.7
EDM2 8.6
Tricho-dento-osseous syndrome 8.4
PanIN-1B 8.4
refractory testicular cancer 8.2
CHH 8.2
bone marrow cancer 8.1
Lymphocystis disease 7.8
BBS9 7.7
bone marrow disorder 7.5
Ganglioglioma 7.1
EBSS 7.1
PanIN-2 7.1
Sotos syndrome 7.1
MDS/MPD 7.0
HSAN1 6.9
PanIN-3 6.8
Bone marrow toxicity 6.8
TGCT 6.8
adult glioblastoma 6.7
Oligodendroglioma 6.6
Alveolar rhabdomyosarcoma 6.6
HP1 6.5
breast fibroadenoma 6.3
disuse osteoporosis 6.3
ADD 6.2
Metastatic colorectal cancer 6.2
brain stem glioma 6.2
functioning pituitary adenoma 6.1
RAEB-T 6.1
ATRX 6.1
DRM 6.0
Endometrioma 5.9
Seckel syndrome 5.9
Selenium deficiency 5.8
hereditary sensory neuropathy 5.8
pediatric medulloblastoma 5.8
choline deficiency 5.8
pediatric solid tumor 5.8
myelodysplastic syndrome 5.8
chronic myelomonocytic leukemia 5.7
DPD deficiency 5.7
IS3 5.6
radiation carcinogenesis 5.6
DSS 5.6
adult AML 5.6
DMM 5.6
laryngeal squamous cell carcinoma 5.5
pineocytoma 5.5
HMS 5.5
leukemogenesis 5.5
refractory cytopenia with multilineage dysplasia 5.3
chronic eosinophilic leukemia 5.3
Shigella sonnei 5.3
metastatic neuroblastoma 5.3
Fibrosarcoma 5.2
FHM 5.2
OCM 5.1
AML/MDS 5.1
oligodendroglioma 5.1
Sertoli-Leydig cell tumor 5.1
Sertoli-Leydig cell tumor 5.1
IS1 5.1
acute myeloid leukemia 5.0
Renal fibrosis 5.0
secondary AML 5.0
acute undifferentiated leukemia 4.9
pineoblastoma 4.9
islet cell carcinoma 4.9
glioblastoma 4.9
Malignant peripheral nerve sheath tumor 4.9
FRAXA 4.8
more...
Symptom
ACHE 4.8
Neuropathic pain 3.2
rigors 3.0
hypersomnia 2.6
cerebellar ataxia 2.4
hip pain 1.8
pelvic pain 1.7
twitching 1.6
exhaustion 1.5
dysuria 1.4
masculinization 1.3
hypotonia 1.1
hoarseness 1.1
bone pain 1.0
starvation 1.0
nausea 0.7
acute pain 0.7
hepatosplenomegaly 0.5
numbness 0.3
shortness of breath 0.3
hyperoxia 0.3
cachexia 0.2
hepatomegaly 0.1
sleepiness -0.0
functional recovery -0.1
ataxia -0.3
dizziness -0.6
splenomegaly -0.6
constipation -0.7
fatigue -0.7
Ill -0.8
thinning -0.8
pain -1.0
stigma -1.1
seizures -1.1
anorexia -1.1
collapse -1.2
diarrhea -1.2
vomiting -1.3
hypothermia -1.4
tremor -1.5
respiratory distress -1.6
cough -1.9
discomfort -1.9
headache -2.1
weakness -2.6
Drug
Zebularine 11.3
Dacogen 11.2
Azacytidine 10.2
Adenyl 8.0
Temodal 7.1
Sinefungin 6.9
Epigallocatechin 6.8
Genasense 6.8
Gliadel 6.6
Cilengitide 6.5
Bexarotene 5.2
APM 5.1
Verteporfin 4.9
MDS 4.7
AGG 4.6
ID2 4.5
CFT 4.4
Mirtazapine 4.4
Lenalidomide 4.3
AC2 4.2
Artesunate 4.2
Fulvestrant 4.2
Vorinostat 4.2
ATV 4.1
GEO 4.0
lysine 4.0
-deoxyadenosine 3.9
Arsenic trioxide 3.9
beta-Galactosidase 3.9
Emodin 3.8
Dihydro 3.6
DNase I 3.5
Clofibrate 3.5
Emodin 3.5
Dasatinib 3.4
Urokinase 3.4
Taxotere 3.4
Methylene blue 3.3
ETS 3.3
Colistin 3.2
Adenosine deaminase 3.2
DMI 3.2
PMEA 3.1
Erlotinib 3.1
VCR 3.0
Irinotecan 3.0
Docetaxel 2.9
Oxaliplatin 2.8
Gel 2.8
CPT-11 2.8
Mutagen 2.7
TAK 2.7
FLP 2.6
Doxycycline 2.6
DMAP 2.5
Retinoic acid 2.5
Gefitinib 2.4
TAT 2.4
Pronase 2.3
Honey 2.3
NBT 2.3
BLM 2.2
Meth 2.2
Alanine 2.2
Gleevec 2.2
Bifidobacterium 2.1
Bortezomib 2.1
Sorafenib 2.1
balanced salt solution 2.1
TAC 2.0
THF 2.0
PTC 1.9
ABC 1.9
Glutathione 1.8
ICI 1.8
TTC 1.8
ADR 1.6
uPA 1.6
ACT 1.6
Paraffin 1.5
more...
Enzyme
DNA methyltransferase 12.6
restriction-modification system 12.6
EC 2.1.1.72 11.4
deoxyribonuclease 10.3
type II restriction enzyme 9.1
histone-lysine N-methyltransferase 8.2
glycine dehydrogenase 7.9
glycine dehydrogenase 7.9
N-acetylglucosaminylphosphotransferase 7.9
protein methylase I 7.8
AlkA 7.8
A-transferase 7.7
protein methylase I 7.7
glycine N-methyltransferase 7.3
glycine dehydrogenase 7.3
cholesterol 25-hydroxylase 7.2
dihydrofolate synthetase 7.1
GDP-mannose 4,6-dehydratase 7.0
deoxyribose-5-phosphate aldolase 6.8
endonuclease 6.7
histone demethylase 6.7
protease La 6.6
agmatine deiminase 6.6
DNA ligase 6.5
DNA ligase 6.5
histone acetyltransferase 6.5
TSA 6.4
phosphatidylethanolamine N-methyltransferase 6.4
betaine-homocysteine methyltransferase 6.3
methioninase 6.3
deoxycytidine deaminase 6.2
PHD 6.2
EC 2.4.99.1 6.2
dCMP deaminase 6.2
matrix metalloproteinase 14 6.2
cytidine deaminase 6.2
phospholipid methyltransferase 6.0
phosphatidylinositol-4,5-bisphosphate 3-kinase 6.0
demethylase 5.9
methylenetetrahydrofolate dehydrogenase 5.9
L-serine dehydratase 5.8
ribokinase 5.8
catechol O-methyltransferase 5.6
T-protein 5.6
hatching enzyme 5.6
threonine dehydrogenase 5.6
methionine synthase 5.5
STK 5.4
methylenetetrahydrofolate dehydrogenase 5.4
methionine synthase 5.4
homocysteine methyltransferase 5.3
methionine adenosyltransferase 5.2
cystathionine gamma-synthase 5.2
isocitrate dehydrogenase 5.1
methionine synthase reductase 5.0
isocitrate dehydrogenase 5.0
uracil phosphoribosyltransferase 5.0
amylomaltase 4.9
farnesyltransferase 4.9
endonuclease VII 4.9
S-adenosylmethionine decarboxylase 4.9
ADE2 4.8
LexA repressor 4.8
GAR 4.7
S-adenosyl-L-homocysteine hydrolase 4.6
phosphoglycerate kinase 4.6
HK2 4.5
CDH 4.5
thymidylate kinase 4.5
farnesyltransferase 4.4
phenylethanolamine N-methyltransferase 4.4
sortase A 4.4
cysteine synthase 4.4
MsrA 4.3
spermidine synthase 4.3
orotidine-5'-phosphate decarboxylase 4.3
orotate phosphoribosyltransferase 4.3
polynucleotide kinase 4.2
chitosanase 4.2
adenine phosphoribosyltransferase 4.2
more...
Compound
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
O6-Methylguanine 11.5
C16H32O2 11.1
C16H32O2 11.1
C16H32O2 11.1
C16H32O2 11.1
C16H32O2 11.1
C16H32O2 10.6
C16H32O2 10.6
C16H32O2 10.6
C16H32O2 10.3
5-Aza-2'-deoxycytidine 10.2
1-methyl-1,4-cyclohexadiene 10.1
C15H20O2 9.6
5-Azacytidine 9.4
octyl octanoate 8.8
Hydrazine sulfate 8.7
DAC 8.7
3-methylbenzaldehyde 8.6
Bisulfite 8.4
3,5-dimethylisoxazole 8.2
Tetrahydrouridine 8.0
Ethionine 7.9
decarboxylated S-adenosylmethionine 7.7
Temozolomide 7.7
MTIC 7.6
Olsalazine 7.5
trimethylsilanol 7.5
ethyl myristate 7.5
Bisdemethoxycurcumin 7.5
TET 7.3
TET 7.3
DIM 7.3
bis(2-chloroethyl) 7.3
adenosylmethionine 7.3
Methylazoxymethanol 7.2
S-adenosylhomocysteine 7.2
bis(2-chloroethyl) 7.2
Theaflavin 7.2
5-Methylcytosine 7.1
Granulin 6.9
CNQ 6.8
Coumermycin 6.8
Phenethyl isothiocyanate 6.8
Anacardic acid 6.8
DAM 6.8
bis(2-chloroethyl) 6.6
LNT 6.6
DAM 6.5
S-methylcysteine 6.5
Procainamide 6.5
Distamycin A 6.4
Cyt 6.3
N-ethylurea 6.3
Sodium bisulfite 6.2
Azoxymethane 6.2
1,2,3-trichloropropane 6.2
BCNU 6.1
Epigallocatechin 6.1
vinyl carbamate 6.1
Potassium permanganate 5.9
3-Deazaneplanocin 5.9
Tazarotene 5.9
Deoxycytidine 5.8
ETH 5.7
more...