Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: EC:2.1.1.37 (DNA methyltransferase)
4,983 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein DNA methyltransferase 4358 DNMT1 579 Mol 555 histone 550 methyltransferase 450 histone deacetylase 429 Sep 312 endonuclease 297 Dnmt1 259 DNMT3A 234 DNMT3B 212 DNA methylase 204 Dnmt3a 173 histone H3 155 p53 126 Dnmt3b 98 methylguanine-DNA methyltransferase 67 telomeric 67 Rett syndrome 61 cytokine 61 p21 58 p16 56 E-cadherin 55 histone methyltransferase 53 estrogen receptor 51 polypeptide 46 DNMT3L 44 GATC 42 CD4 41 HDAC1 41 Dnmt2 40 fused 39 DNA repair protein 38 DNMT2 37 insulin 36 DAC 36 Sp1 35 DNA repair enzyme 34 HDAC 33 tumour suppressor 33 MET1 33 lymphoid 31 EZH2 31 ubiquitin 31 histone acetyltransferase 31 Adenosine deaminase 31 proliferating cell nuclear antigen 31 caspase-3 31 IFN 30 Gen 29 ATP 29 RASSF1A 28 erythroid 28 tRNA 27 Bcl-2 27 catenin 27 mer 26 thymus 26 interferon 26 histone H4 26 MBD2 26 AML 26 proteasome 24 IDH1 24 transcriptional repressor 23 Histone deacetylase 23 p15 22 histone deacetylase 1 22 RNA polymerase II 22 OCT4 22 UTR 22 mTOR 22 ERK 22 IL-6 21 TET2 21 CD34 21 p16INK4a 21 DNA-binding protein 21 ATPase 21 brain-derived neurotrophic factor 20 more...

Disease cancer 1162 tumor 808 carcinogenesis 260 tumorigenesis 197 acute myeloid leukemia 182 breast cancer 174 leukemia 144 myelodysplastic syndrome 126 carcinoma 106 colorectal cancer 104 glioblastoma 84 hepatocellular carcinoma 81 glioma 74 lung cancer 72 prostate cancer 66 tumor progression 66 tumor growth 65 MCF 61 immunodeficiency 60 gastric cancer 54 colon cancer 52 melanoma 45 adenocarcinoma 42 ovarian cancer 37 lymphoma 35 Leukemia 33 hematologic malignancies 31 diabetes 31 multiple myeloma 28 atherosclerosis 28 leukemogenesis 28 Alzheimer's disease 26 pancreatic cancer 26 systemic lupus erythematosus 25 squamous cell carcinoma 25 glioblastoma multiforme 23 metastases 23 non-small cell lung cancer 23 lupus 21 brain tumor 21 B-cell lymphoma 20 lupus 20 Epstein 19 acute lymphoblastic leukemia 19 obesity 19 SDS 18 cervical cancer 18 cold 17 erythroleukemia 17 epithelial ovarian cancer 17 bladder cancer 17 Haemophilus 17 ATM 16 CHH 16 retinoblastoma 16 schizophrenia 15 neuroblastoma 15 Burkitt's lymphoma 15 HIV 15 sarcoma 15 liver cancer 14 acute leukemia 14 myelosuppression 14 aggressiveness 14 HP1 14 APC 14 DSS 13 infectious diseases 13 chronic myeloid leukemia 13 endometrial cancer 13 hepatitis B 13 virus infection 13 cytomegalovirus 12 hypertension 12 liver cancer 12 sickle cell disease 12 myeloproliferative disorders 11 cirrhosis 11 suicide 11 Glioblastoma 11 more...

Symptom pain 21 starvation 8 seizures 6 nausea 6 exhaustion 6 fatigue 5 diarrhea 4 cerebellar ataxia 3 ataxia 2 Neuropathic pain 2 functional recovery 2 pelvic pain 2 sleepiness 2 collapse 2 vomiting 2 hypotonia 2 headache 2 dysuria 1 hip pain 1 ACHE 1 thinning 1 cachexia 1 hoarseness 1 bone pain 1 stigma 1 dizziness 1 twitching 1 anorexia 1 masculinization 1 constipation 1 splenomegaly 1 hypersomnia 1 acute pain 1 tremor 1 hyperoxia 1 discomfort 1 weakness 1 numbness 1 Ill 1 cough 1 shortness of breath 1 respiratory distress 1 hepatomegaly 1 rigors 1 hepatosplenomegaly 1 hypothermia 1

Drug lysine 149 Zebularine 28 Azacytidine 17 Gel 16 DNase I 15 IFN-gamma 11 MDS 9 Dacogen 8 Epigallocatechin 8 ROS 8 IL-2 8 Dermatol 6 Mutagen 6 ascorbate 6 Asn 5 -deoxyadenosine 5 THF 5 MAP 5 ABC 5 caffeine 4 NADH 4 ETS 4 Bifidobacterium 4 GEO 4 ampicillin 4 AGG 3 ICI 3 lactose 3 Glutathione 3 Leaf 3 DMI 3 Retinoic acid 3 CSF 3 Arsenic trioxide 3 Docetaxel 2 Monit 2 VCR 2 Lenalidomide 2 Ethanol 2 Alanine 2 CFT 2 Methylene blue 2 CaCl2 2 CaCl2 2 CPT-11 2 Biopolymers 2 CaCl2 2 Adriamycin 2 TAT 2 BLM 1 Genasense 1 Honey 1 Verteporfin 1 Erlotinib 1 Pronase 1 ID2 1 Vorinostat 1 APM 1 Alliance 1 Adenosine deaminase 1 balanced salt solution 1 Growth hormone 1 NH3 1 Indomethacin 1 Dasatinib 1 MOF 1 NBT 1 Sorafenib 1 SiO2 1 Gliadel 1 Asthma 1 CDP 1 Vitamin A 1 beta-Galactosidase 1 Capsicum 1 Mirtazapine 1 Sinefungin 1 TTC 1 EE2 1 ADR 1 more...

Enzyme DNA methyltransferase 4983 restriction-modification system 349 deoxyribonuclease 306 endonuclease 297 ERK 78 luciferase 54 RNA polymerase 53 demethylase 53 mitogen-activated protein kinase 47 DNA ligase 39 DNA ligase 39 histone acetyltransferase 38 focal adhesion kinase 34 protein kinase 33 proteasome 25 glutathione S-transferase 24 ATPase 22 PARP 20 topoisomerase 20 MEK 20 topoisomerase 19 DNA polymerase 18 reverse transcriptase 18 isocitrate dehydrogenase 17 isocitrate dehydrogenase 17 TSA 16 DNase 16 caspase-3 16 histone demethylase 15 superoxide dismutase 15 APC 13 RNase 13 P-glycoprotein 12 RNase 12 transcriptase 12 cytidine deaminase 11 PHD 10 catalase 10 trypsin 9 peroxidase 8 phosphoglycerate kinase 8 micrococcal nuclease 8 ACS 8 alkaline phosphatase 8 calcineurin 8 phosphoinositide 3-kinase 8 ornithine decarboxylase 7 chloramphenicol acetyltransferase 7 thymidylate synthase 7 phosphatidylinositol 3-kinase 7 cdc2 7 protein kinase C 6 invertase 6 methionine synthase 6 thymidine kinase 6 methionine synthase 6 NQO1 6 NO synthase 6 ribonucleotide reductase 5 caspase-9 5 AMP-activated protein kinase 5 farnesyltransferase 5 beta-galactosidase 5 farnesyltransferase 5 MMP 4 S1 nuclease 4 lysozyme 4 dihydrofolate reductase 4 AlkA 4 methylenetetrahydrofolate reductase 4 aldehyde dehydrogenase 4 NOS 4 methylenetetrahydrofolate reductase 4 aldehyde dehydrogenase 4 aldehyde dehydrogenase 4 methionine adenosyltransferase 4 ribonuclease 4 deaminase 4 ribonuclease 4 glyceraldehyde-3-phosphate dehydrogenase 4 more...

Compound DNA 3486 Dec 343 adenosylmethionine 202 methionine 174 lysine 169 5-Aza-2'-deoxycytidine 112 Clin 83 oxygen 76 Bisulfite 68 sodium 66 S-adenosylhomocysteine 64 MDA 58 cysteine 55 glucose 52 phosphate 48 5-Azacytidine 47 O6-Methylguanine 44 water 40 Cyt 38 homocysteine 38 DAC 36 arginine 36 zinc 36 hydrogen 34 retinoic acid 33 salt 33 ATP 29 calcium 27 sulfate 26 Temozolomide 26 tyrosine 26 alanine 25 pyrimidine 25 BCNU 25 pyrimidine 25 MTT 24 tryptophan 24 bis(2-chloroethyl) 23 Histone 23 bis(2-chloroethyl) 23 bis(2-chloroethyl) 23 serine 21 TNF 19 His 19 SDS 19 acetate 19 Adenine 18 TEM 18 DIM 18 MEK 17 bromide 17 leucine 17 TET 16 TET 16 DEAE 16 cAMP 15 ethanol 15 cadmium 14 Asp 14 GSH 14 GSH 14 iron 13 urea 13 nitric oxide 13 iodine 13 Mg2+ 13 benzene 12 tryptophan 12 pyrene 12 Phe 12 tryptophan 12 tryptophan 12 TNM 12 Gly 11 glutamine 11 nitrogen 11 SET 11 galactose 10 Bisphenol A 10 proline 10 more...

---