Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.1.1.37 (DNA methyltransferase)
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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
N6AMT2 12.6
HASJ4442 12.6
Mucin-like protocadherin 12.6
ZSWIM3 12.6
ZBTB38 protein 12.6
Protease, serine, 3 12.6
DNA methyltransferase 12.6
GRG3 12.6
DNA methylase 12.6
DNMT3A protein 11.9
DNMT2 protein 11.9
Dnmt2 11.7
Opioid binding protein/cell adhesion molecule-like 11.6
HIST1H2AA 11.6
H4F2 11.6
CDK5 regulatory subunit-associated protein 1 11.6
WD repeat and FYVE domain containing 3 11.6
attractin-like 1 11.6
purinergic receptor P2RY11 11.6
DNMT2 11.5
HEMK2 11.3
DNMT3L 11.2
ATRNL1 11.1
U2 small nuclear RNA auxiliary factor 1 11.1
formin homology 2 domain containing 1 11.1
CRBPIV 11.1
myosin light chain kinase 3 11.1
zinc finger protein 57 11.1
XAGE3 11.1
Dnmt1 11.0
Dnmt3a 11.0
TRDMT1 10.9
Dnmt3b 10.8
Zinc finger protein 382 10.6
opioid binding protein/cell adhesion molecule-like 10.6
Vsm-RhoGEF 10.6
LMO6 10.6
MUPCDH 10.6
DCUN1D2 10.6
Dedicator of cytokinesis 1 10.6
more...
Disease
pancreatic cancer stage 11.1
Oligoastrocytoma 11.1
Oligoastrocytoma 11.1
Diffuse pulmonary fibrosis 10.6
CIID 9.8
ovarian mixed germ cell tumor 9.5
CLAM 8.8
AD7 8.7
Cocaine withdrawal 8.7
EDM2 8.6
PanIN-1B 8.4
Tricho-dento-osseous syndrome 8.4
refractory testicular cancer 8.2
CHH 8.2
bone marrow cancer 8.1
Lymphocystis disease 7.8
BBS9 7.7
bone marrow disorder 7.5
Ganglioglioma 7.1
EBSS 7.1
PanIN-2 7.1
Sotos syndrome 7.1
MDS/MPD 7.0
HSAN1 6.9
PanIN-3 6.8
Bone marrow toxicity 6.8
TGCT 6.8
adult glioblastoma 6.7
Oligodendroglioma 6.6
Alveolar rhabdomyosarcoma 6.6
HP1 6.5
breast fibroadenoma 6.3
disuse osteoporosis 6.3
ADD 6.2
Metastatic colorectal cancer 6.2
brain stem glioma 6.2
functioning pituitary adenoma 6.1
RAEB-T 6.1
ATRX 6.1
DRM 6.0
more...
Symptom
ACHE 4.8
Neuropathic pain 3.2
rigors 3.0
hypersomnia 2.6
cerebellar ataxia 2.4
hip pain 1.8
pelvic pain 1.7
twitching 1.6
exhaustion 1.5
dysuria 1.4
masculinization 1.3
hypotonia 1.1
hoarseness 1.1
bone pain 1.0
starvation 1.0
nausea 0.7
acute pain 0.7
hepatosplenomegaly 0.5
numbness 0.3
shortness of breath 0.3
hyperoxia 0.3
cachexia 0.2
hepatomegaly 0.1
sleepiness -0.0
functional recovery -0.1
ataxia -0.3
dizziness -0.6
splenomegaly -0.6
constipation -0.7
fatigue -0.7
Ill -0.8
thinning -0.8
pain -1.0
stigma -1.1
seizures -1.1
anorexia -1.1
collapse -1.2
diarrhea -1.2
vomiting -1.3
hypothermia -1.4
more...
Drug
Zebularine 11.3
Dacogen 11.2
Azacytidine 10.2
Adenyl 8.0
Temodal 7.1
Sinefungin 6.9
Epigallocatechin 6.8
Genasense 6.8
Gliadel 6.6
Cilengitide 6.5
Bexarotene 5.2
APM 5.1
Verteporfin 4.9
MDS 4.7
AGG 4.6
ID2 4.5
CFT 4.4
Mirtazapine 4.4
Lenalidomide 4.3
AC2 4.2
Artesunate 4.2
Fulvestrant 4.2
Vorinostat 4.2
ATV 4.1
GEO 4.0
lysine 4.0
-deoxyadenosine 3.9
Arsenic trioxide 3.9
beta-Galactosidase 3.9
Emodin 3.8
Dihydro 3.6
DNase I 3.5
Clofibrate 3.5
Emodin 3.5
Dasatinib 3.4
Urokinase 3.4
Taxotere 3.4
Methylene blue 3.3
ETS 3.3
Colistin 3.2
more...
Enzyme
DNA methyltransferase 12.6
restriction-modification system 12.6
EC 2.1.1.72 11.4
deoxyribonuclease 10.3
type II restriction enzyme 9.1
histone-lysine N-methyltransferase 8.2
glycine dehydrogenase 7.9
glycine dehydrogenase 7.9
N-acetylglucosaminylphosphotransferase 7.9
protein methylase I 7.8
AlkA 7.8
A-transferase 7.7
protein methylase I 7.7
glycine N-methyltransferase 7.3
glycine dehydrogenase 7.3
cholesterol 25-hydroxylase 7.2
dihydrofolate synthetase 7.1
GDP-mannose 4,6-dehydratase 7.0
deoxyribose-5-phosphate aldolase 6.8
endonuclease 6.7
histone demethylase 6.7
protease La 6.6
agmatine deiminase 6.6
DNA ligase 6.5
DNA ligase 6.5
histone acetyltransferase 6.5
TSA 6.4
phosphatidylethanolamine N-methyltransferase 6.4
betaine-homocysteine methyltransferase 6.3
methioninase 6.3
deoxycytidine deaminase 6.2
PHD 6.2
EC 2.4.99.1 6.2
dCMP deaminase 6.2
matrix metalloproteinase 14 6.2
cytidine deaminase 6.2
phospholipid methyltransferase 6.0
phosphatidylinositol-4,5-bisphosphate 3-kinase 6.0
demethylase 5.9
methylenetetrahydrofolate dehydrogenase 5.9
more...
Compound
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
C16H32O2 11.6
O6-Methylguanine 11.5
C16H32O2 11.1
C16H32O2 11.1
C16H32O2 11.1
C16H32O2 11.1
C16H32O2 11.1
C16H32O2 10.6
C16H32O2 10.6
C16H32O2 10.6
C16H32O2 10.3
5-Aza-2'-deoxycytidine 10.2
1-methyl-1,4-cyclohexadiene 10.1
C15H20O2 9.6
5-Azacytidine 9.4
octyl octanoate 8.8
Hydrazine sulfate 8.7
DAC 8.7
3-methylbenzaldehyde 8.6
Bisulfite 8.4
3,5-dimethylisoxazole 8.2
Tetrahydrouridine 8.0
Ethionine 7.9
decarboxylated S-adenosylmethionine 7.7
Temozolomide 7.7
more...