Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: EC:2.1.1.37 (DNA methyltransferase)
4,983 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein DNA methyltransferase 4358 DNMT1 579 Mol 555 histone 550 methyltransferase 450 histone deacetylase 429 Sep 312 endonuclease 297 Dnmt1 259 DNMT3A 234 DNMT3B 212 DNA methylase 204 Dnmt3a 173 histone H3 155 p53 126 Dnmt3b 98 methylguanine-DNA methyltransferase 67 telomeric 67 Rett syndrome 61 cytokine 61 p21 58 p16 56 E-cadherin 55 histone methyltransferase 53 estrogen receptor 51 polypeptide 46 DNMT3L 44 GATC 42 CD4 41 HDAC1 41 Dnmt2 40 fused 39 DNA repair protein 38 DNMT2 37 DAC 36 insulin 36 Sp1 35 DNA repair enzyme 34 MET1 33 HDAC 33 more...

Disease cancer 1162 tumor 808 carcinogenesis 260 tumorigenesis 197 acute myeloid leukemia 182 breast cancer 174 leukemia 144 myelodysplastic syndrome 126 carcinoma 106 colorectal cancer 104 glioblastoma 84 hepatocellular carcinoma 81 glioma 74 lung cancer 72 tumor progression 66 prostate cancer 66 tumor growth 65 MCF 61 immunodeficiency 60 gastric cancer 54 colon cancer 52 melanoma 45 adenocarcinoma 42 ovarian cancer 37 lymphoma 35 Leukemia 33 hematologic malignancies 31 diabetes 31 multiple myeloma 28 leukemogenesis 28 atherosclerosis 28 Alzheimer's disease 26 pancreatic cancer 26 systemic lupus erythematosus 25 squamous cell carcinoma 25 metastases 23 glioblastoma multiforme 23 non-small cell lung cancer 23 brain tumor 21 lupus 21 more...

Symptom pain 21 starvation 8 exhaustion 6 nausea 6 seizures 6 fatigue 5 diarrhea 4 cerebellar ataxia 3 pelvic pain 2 vomiting 2 Neuropathic pain 2 functional recovery 2 sleepiness 2 collapse 2 ataxia 2 hypotonia 2 headache 2 dysuria 1 hip pain 1 ACHE 1 thinning 1 cachexia 1 hoarseness 1 bone pain 1 weakness 1 numbness 1 dizziness 1 constipation 1 splenomegaly 1 anorexia 1 acute pain 1 tremor 1 hyperoxia 1 discomfort 1 Ill 1 cough 1 shortness of breath 1 respiratory distress 1 hepatomegaly 1 rigors 1 more...

Drug lysine 149 Zebularine 28 Azacytidine 17 Gel 16 DNase I 15 IFN-gamma 11 MDS 9 ROS 8 IL-2 8 Dacogen 8 Epigallocatechin 8 Mutagen 6 ascorbate 6 Dermatol 6 -deoxyadenosine 5 ABC 5 Asn 5 MAP 5 THF 5 ampicillin 4 ETS 4 GEO 4 Bifidobacterium 4 caffeine 4 NADH 4 Glutathione 3 AGG 3 lactose 3 Leaf 3 Retinoic acid 3 Arsenic trioxide 3 ICI 3 CSF 3 DMI 3 Monit 2 Biopolymers 2 Docetaxel 2 Lenalidomide 2 VCR 2 Alanine 2 more...

Enzyme DNA methyltransferase 4983 restriction-modification system 349 deoxyribonuclease 306 endonuclease 297 ERK 78 luciferase 54 demethylase 53 RNA polymerase 53 mitogen-activated protein kinase 47 DNA ligase 39 DNA ligase 39 histone acetyltransferase 38 focal adhesion kinase 34 protein kinase 33 proteasome 25 glutathione S-transferase 24 ATPase 22 PARP 20 MEK 20 topoisomerase 20 topoisomerase 19 DNA polymerase 18 reverse transcriptase 18 isocitrate dehydrogenase 17 isocitrate dehydrogenase 17 DNase 16 caspase-3 16 TSA 16 superoxide dismutase 15 histone demethylase 15 RNase 13 APC 13 transcriptase 12 RNase 12 P-glycoprotein 12 cytidine deaminase 11 PHD 10 catalase 10 trypsin 9 peroxidase 8 more...

Compound DNA 3486 Dec 343 adenosylmethionine 202 methionine 174 lysine 169 5-Aza-2'-deoxycytidine 112 Clin 83 oxygen 76 Bisulfite 68 sodium 66 S-adenosylhomocysteine 64 MDA 58 cysteine 55 glucose 52 phosphate 48 5-Azacytidine 47 O6-Methylguanine 44 water 40 Cyt 38 homocysteine 38 arginine 36 DAC 36 zinc 36 hydrogen 34 retinoic acid 33 salt 33 ATP 29 calcium 27 tyrosine 26 sulfate 26 Temozolomide 26 alanine 25 pyrimidine 25 pyrimidine 25 BCNU 25 MTT 24 tryptophan 24 bis(2-chloroethyl) 23 bis(2-chloroethyl) 23 Histone 23 more...

---