Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.9.3.1 (
cytochrome oxidase
)
8,822
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
cytochrome
866
cytochrome aa3
865
cytochrome c oxidase
816
Mol
759
cytochrome c
746
ATP
627
Sep
574
AED
423
NADH
422
cytochrome b
311
citrate synthase
274
ATPase
265
catalase
194
ADP
187
lactate dehydrogenase
184
superoxide dismutase
179
hemoglobin
161
Cytochrome c
149
peroxidase
137
ATP synthase
136
reductase
135
NADH dehydrogenase
127
cryptic
126
COX
122
NAD
119
tRNA
116
polypeptide
111
ubiquinone
109
COI
105
nitric oxide synthase
105
acid phosphatase
100
oxidoreductase
99
acetylcholinesterase
98
malate dehydrogenase
97
EPR
97
insulin
93
membrane-bound
90
axonal
78
NADPH
75
Pseudomonas
75
complex I)
74
membrane protein
73
myoglobin
71
Gen
67
ROS
66
creatine kinase
66
parvalbumin
66
alkaline phosphatase
66
endoplasmic reticulum
65
microsomal
64
glutamate dehydrogenase
63
GSH
61
esterase
58
nov
57
phosphofructokinase
56
CO2
54
hexokinase
54
caspase-3
53
PGC
53
glucose-6-phosphate dehydrogenase
52
fused
49
pyruvate dehydrogenase
49
COII
49
calbindin
49
isocitrate dehydrogenase
48
pyruvate kinase
47
COX1
47
cox1
47
ferrocytochrome c:oxygen oxidoreductase
44
SDS
43
acyl-CoA oxidase
42
glutathione peroxidase
41
dimeric
40
proton pump
40
GABA
39
peroxisome proliferator-activated receptor
39
glucose-6-phosphatase
38
aconitase
37
uncoupling protein
37
AMP
36
more...
Disease
Alzheimer's disease
154
ischemia
143
cold
103
Parkinson's disease
100
cancer
98
Leigh syndrome
92
depression
81
myopathy
72
lactic acidosis
72
mitochondrial disease
70
tumor
69
diabetes
64
GSH
61
stroke
58
cardiomyopathy
53
encephalopathy
46
obesity
43
SDS
43
mitochondrial myopathy
39
epilepsy
38
West
36
Huntington's disease
35
malaria
34
amyotrophic lateral sclerosis
29
hypertension
29
heart failure
29
neuroblastoma
28
sepsis
28
worms
28
hepatocellular carcinoma
27
mole
27
mole
27
dementia
26
sepsis
26
developmental delay
25
cerebral ischemia
24
neuropathy
23
Menkes
21
failure to thrive
20
SEM
20
anemia
20
pheochromocytoma
19
multiple sclerosis
19
IVA
18
hypertrophic cardiomyopathy
18
hypothyroidism
18
Brown
18
cognitive impairment
18
fits
18
PCC
17
schizophrenia
16
MELAS
16
NAME
16
iron deficiency
16
cholera
16
hyperglycemia
16
OPA1
15
type 2 diabetes
15
Kearns-Sayre syndrome
15
Echinococcus
15
HIV
14
optic atrophy
14
myocardial ischemia
14
MELAS
14
carcinoma
14
respiratory failure
14
strabismus
13
myocardial infarction
12
coma
12
cirrhosis
12
lice
12
mitochondrial encephalomyopathy
12
malnutrition
12
cataract
12
peripheral neuropathy
12
cardiovascular disease
11
confusion
11
hypoglycemia
11
deafness
11
Copper deficiency
11
more...
Symptom
seizures
67
hypotonia
57
weakness
47
ataxia
35
anesthesia
33
ophthalmoplegia
25
collapse
23
fatigue
22
exhaustion
20
hyperoxia
20
starvation
14
hepatomegaly
13
vomiting
13
functional recovery
12
pain
12
dystonia
9
hypothermia
9
lethargy
8
tremor
7
cerebellar ataxia
6
myalgia
6
respiratory distress
6
cachexia
5
dyspnea
5
memory loss
5
diarrhea
5
headache
5
dysarthria
4
myoclonus
4
thinning
4
hypercapnia
4
nausea
4
chorea
4
Decreased activity
4
constipation
3
cyanosis
3
paresis
3
spasticity
3
hangover
3
paraparesis
3
stigma
3
Exercise intolerance
3
anorexia
3
Anoxia
2
torticollis
2
sleepiness
2
dizziness
2
Excitability
2
tachypnea
2
acute stress
2
incoordination
2
splenomegaly
2
agitation
2
neurological disability
2
apathy
2
angina
2
Mills
2
Wind
2
pallor
2
cough
1
ketonuria
1
restriction of respiration
1
DNA marker
1
despair
1
polyuria
1
asthenia
1
Ill
1
regurgitation
1
dysosmia
1
insomnia
1
fasciculation
1
acidity
1
erythema
1
Drugged
1
vertigo
1
masculinization
1
male subfertility
1
Reticulocytosis
1
autodigestion
1
spasm
1
more...
Drug
NADH
434
ascorbate
149
lysine
67
ROS
66
Heme
30
FAD
26
citric acid
20
vitamin E
19
Gel
17
CSF
14
Cardiovasc
13
Ethanol
10
AZT
9
AZT
9
Methylene blue
9
Leaf
9
Nephron
8
lactose
8
caffeine
8
Reserpine
7
Dermatol
7
Glutathione
6
Asn
6
NH3
6
PCP
6
Singular
5
NBT
5
Kenyan
5
Adriamycin
5
ALA
4
ampicillin
4
ICI
4
ABC
4
Atabrine
4
Senna
4
Vitamin A
4
Senna
4
CTX
3
p75
3
Galactose
3
DHT
3
Indomethacin
3
Monit
3
Parkin
3
DNase I
3
Propofol
3
Acacia
3
Digenea
3
Nitric Oxide
3
Vitamin K
3
pyridoxal phosphate
3
Fragment
3
DHT
3
THF
3
Glucagon
3
niacin
3
Retinoic acid
3
Parkin
3
Trifluoperazine
2
EE2
2
Fructose
2
Vitamin E
2
MAP
2
Naftidrofuryl
2
Vitamin B12
2
Simvastatin
2
Doxycycline
2
CaCl2
2
Alanine
2
Portal
2
Papaverine
2
ETA
2
CaCl2
2
CaCl2
2
Cytidine
2
Frontal
2
Riboflavin
2
URF
2
Retinoic Acid
2
CDP
2
more...
Enzyme
cytochrome oxidase
8822
complex I
696
succinate dehydrogenase
640
ATPase
379
diaphorase
340
citrate synthase
281
superoxide dismutase
204
catalase
201
lactate dehydrogenase
199
CPR
195
ATP synthase
181
peroxidase
163
NADH dehydrogenase
128
malate dehydrogenase
114
succinic dehydrogenase
110
acetylcholinesterase
104
acid phosphatase
100
creatine kinase
74
monoamine oxidase
72
NO synthase
70
alkaline phosphatase
66
glutamate dehydrogenase
64
glutamate dehydrogenase
64
NADPH-diaphorase
63
pyruvate dehydrogenase
62
glutamate dehydrogenase
62
glucose-6-phosphate dehydrogenase
58
phosphofructokinase
58
hexokinase
54
isocitrate dehydrogenase
52
pyruvate dehydrogenase
51
isocitrate dehydrogenase
51
pyruvate dehydrogenase
49
NQO1
47
pyruvate kinase
47
caspase-3
43
glutathione peroxidase
42
ceruloplasmin
40
aconitase
39
phosphorylase
39
glucose-6-phosphatase
38
diaphorase
36
aspartate aminotransferase
35
nitrite reductase
30
nitrite reductase
29
nitrite reductase
29
ubiquinol-cytochrome c oxidoreductase
29
glycerol-3-phosphate dehydrogenase
29
glycerol-3-phosphate dehydrogenase
28
alpha-ketoglutarate dehydrogenase
27
AMP-activated protein kinase
26
protein kinase
25
beta-glucuronidase
23
5'-nucleotidase
22
glutathione reductase
21
fumarase
21
cholinesterase
21
alanine aminotransferase
20
glyceraldehyde-3-phosphate dehydrogenase
20
beta-hydroxybutyrate dehydrogenase
20
CPT
20
dihydrofolate reductase
18
xanthine oxidase
18
3-hydroxyacyl-CoA dehydrogenase
18
tyrosine hydroxylase
18
cytochrome c peroxidase
18
beta-galactosidase
17
glutathione S-transferase
17
glyceraldehyde-3-phosphate dehydrogenase
17
mitogen-activated protein kinase
17
choline acetyltransferase
16
glyceraldehyde-3-phosphate dehydrogenase
16
NOS
16
reverse transcriptase
15
3-hydroxyacyl-CoA dehydrogenase
15
alcohol dehydrogenase
15
NADPH oxidase
15
glyceraldehyde-3-phosphate dehydrogenase
15
nitrate reductase
14
NADPH oxidase
14
more...
Compound
oxygen
1422
DNA
1372
ATP
629
Dec
627
cyanide
460
NADH
433
copper
416
glucose
330
water
330
sodium
265
iron
254
nitric oxide
241
calcium
240
ADP
201
CO2
200
phosphate
191
ADP
188
ADP
188
hydrogen
178
glutamate
172
NAD
152
Cytochrome c
149
COX
122
NAD
119
nitrogen
115
Clin
110
ubiquinone
107
COI
107
potassium
98
nicotinamide
93
His
91
H2O2
90
ethanol
89
ubiquinol
85
leucine
80
lysine
80
NADPH
75
NADPH
75
cysteine
72
zinc
72
sulfate
71
GSH
70
GSH
70
methionine
69
arginine
69
Cereb
64
nitrate
62
acetate
60
galactose
57
salt
54
SDS
53
tyrosine
53
Cyt
53
H2S
52
Triton X-100
51
succinic acid
50
alanine
46
bromide
43
ammonium
42
glycerol
41
CoA
40
tryptophan
40
tryptophan
40
GABA
40
tryptophan
39
tryptophan
39
GABA
39
AMP
38
TMPD
37
H2S
37
NADP
36
urea
35
GDP
35
phosphocreatine
34
manganese
32
Heme
31
proline
31
serine
30
2-oxoglutarate
29
Mg2+
27
more...