Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.9.3.1 (cytochrome oxidase)
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Human Gene/Protein
COX7A2L protein 11.8
C20orf24 11.8
CCDC56 11.8
C1orf31 11.8
C2orf64 11.8
MMA-1 11.8
MRPS14 11.8
ferrocytochrome c:oxygen oxidoreductase 11.8
serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform 11.8
C1orf163 11.8
COX7a-related protein 11.8
mature T-cell proliferation 1 11.8
COX11 protein 11.8
FASTKD5 11.2
cytochrome oxidase assembly factor 11.2
LSFC 11.0
cytochrome aa3 10.8
COX7B2 10.8
G8 protein 10.8
HIGD2A 10.8
transmembrane 7 superfamily member 2 10.8
EARS2 protein 10.8
interferon regulatory factor 2 binding protein 1 10.8
dehydrogenase/reductase member 3 10.8
AED 10.7
COX VIII-L 10.5
FAM36A 10.5
COX7A2L 10.4
COX18 10.4
SURF-1 10.3
Lon protease homolog 10.2
TIMM9 10.2
cytochrome c oxidase subunit VIa polypeptide 1 10.2
COI protein 10.2
mitochondrial ribosomal protein S11 10.2
PET112 10.2
C2orf34 10.2
COX16 10.1
SURF1 10.1
COX19 10.0
more...
Disease
LSFC 11.0
Gyrodactylosis 10.8
Swayback 10.8
Disorders of mitochondrial metabolism 9.8
Wound myiasis 9.2
Complex III deficiency 9.0
Cytochrome c oxidase deficiency 8.8
Fecal peritonitis 8.4
Biventricular hypertrophy 8.4
late onset disorder 8.1
ATP synthase deficiency 8.1
COND 8.1
Leigh syndrome 7.8
MILS 7.7
Congenital fiber type disproportion 7.6
Complex I deficiency 7.5
CRD1 7.4
MERRF 7.4
NIID 7.3
Neonatal encephalopathy 7.3
EBS2 7.2
MNGIE 7.2
Alpers 7.1
mitochondrial disease 7.1
Chronic hyponatremia 7.1
Cocaine use disorder 7.1
Mitochondrial DNA depletion 7.1
mitochondrial myopathy 7.0
Copper deficiency 6.9
endophlebitis 6.9
PDH deficiency 6.9
RCA1 6.9
arbovirus disease 6.9
EBS1 6.8
MELAS 6.7
sulfhemoglobinemia 6.7
Zoonotic cutaneous leishmaniasis 6.7
MELAS 6.6
disorders of amino acid metabolism 6.6
Kearns-Sayre syndrome 6.4
more...
Symptom
Angioscotoma 11.8
restriction of respiration 9.8
Drugged 7.9
Exercise intolerance 6.6
Reticulocytosis 6.2
dysosmia 5.3
hypotonia 5.1
hangover 4.9
Decreased activity 4.8
ophthalmoplegia 4.8
Excitability 4.5
Deafferentation 4.4
Extrapyramidal symptoms 4.2
giddiness 4.2
giddiness 4.2
labored breathing 4.1
hyperoxia 3.8
male subfertility 3.8
Anoxia 3.7
urethral discharge 3.6
autodigestion 3.5
prostration 3.3
hepatomegaly 3.0
ataxia 3.0
neurological disability 3.0
chorea 2.8
ketonuria 2.7
breath holding 2.7
cerebellar ataxia 2.6
Mills 2.5
exhaustion 2.4
lethargy 2.3
memory loss 2.3
clonus 2.3
weakness 2.2
torticollis 2.2
incoordination 2.0
paraparesis 2.0
DNA marker 2.0
dystonia 1.9
more...
Drug
Haloperidol Decanoate 9.2
Duroquinone 8.2
Atabrine 7.9
Ferumoxides 7.2
Sodium Nitroprusside 7.2
Naftidrofuryl 6.6
URF 6.3
NADH 6.2
Sodium ascorbate 6.1
Epidoxorubicin 6.0
Folic Acid 5.8
Senna 5.6
3,4-Dihydroxyphenylalanine 5.5
Senna 5.5
Fusicoccin 5.4
7-Nitroindazole 5.4
Zinc sulfate 5.3
Zinc sulfate 5.3
Sodium thiosulfate 5.2
Singular 5.2
Heme 5.1
Cytidine 5.0
Protamine sulfate 4.9
Hyperforin 4.8
Reserpine 4.7
Methylene blue 4.7
ascorbate 4.5
Lead acetate 4.5
Fenbendazole 4.5
Flavin 4.4
Retinoic Acid 4.3
Tween 40 4.2
Digenea 4.1
FAD 4.1
Trifluoperazine 4.0
Papaverine 3.9
Thioridazine 3.9
Photofrin II 3.8
NBT 3.8
Cobalamin 3.8
more...
Enzyme
cytochrome oxidase 11.8
EC 2.1.1.16 10.2
farnesol dehydrogenase 9.8
ubiquinol-cytochrome c oxidoreductase 9.3
glucoside 3-dehydrogenase 8.4
hydroxylamine oxidase 8.2
succinate dehydrogenase 8.1
complex I 8.1
succinic dehydrogenase 7.8
citrate synthase 7.8
D-cysteine desulfhydrase 7.8
NADH dehydrogenase 7.8
diaphorase 7.7
beta-hydroxybutyrate dehydrogenase 7.6
hypodermin C 7.2
glyoxylate reductase 7.1
LTB4 omega-hydroxylase 7.1
glyoxylate reductase 7.1
CPR 7.1
beta-glycerophosphatase 7.1
thiosulfate dehydrogenase 7.1
i-AAA protease 7.0
glycolate dehydrogenase 7.0
2-oxoglutarate decarboxylase 6.9
hydroxylamine reductase 6.8
hydroxylamine reductase 6.8
nitrous oxide reductase 6.7
2-hydroxyglutarate dehydrogenase 6.7
acyl-CoA reductase 6.7
3-hydroxyacyl-CoA dehydrogenase 6.6
cytochrome c peroxidase 6.5
ATP synthase 6.5
3-hydroxy-3-methylglutaryl-CoA lyase 6.5
acetylornithine aminotransferase 6.5
malate dehydrogenase 6.5
glycine dehydrogenase 6.5
DHOdehase 6.4
aconitase 6.3
3-hydroxyacyl-CoA dehydrogenase 6.3
p-cresol methylhydroxylase 6.3
more...
Compound
Cue-lure 11.8
C33H54O4 11.8
C33H54O4 11.8
Diaminomaleonitrile 11.8
Ubisemiquinone 10.8
4-hydroxy-4-(3-pyridyl)-butanoic acid 10.2
4'-Epiadriamycin 9.8
sebacamide 9.8
C33H54O4 9.5
Durohydroquinone 9.5
Cytochrome c1 9.3
TMPD 9.3
2-Bromohydroquinone 9.2
Rapanone 9.2
heme O 9.1
C5H6O4 8.8
2-methyl-3-hydroxybutyryl-CoA 8.8
Heliotrine 8.8
o-Iodosobenzoate 8.8
Pyrrolnitrin 8.8
Heliotrine 8.6
heptanamide 8.6
Cobinamide 8.6
C5H6O4 8.5
Menadiol 8.5
Diiodothyronine 8.2
10-formyldihydrofolate 8.2
Cytochrome c 8.1
3-succinoylpyridine 8.0
2,2',5,5'-TCB 7.9
propyl carbamate 7.8
Duroquinone 7.7
Salicylaldoxime 7.7
3-T1 7.6
Dehydrocostus lactone 7.6
Isovitexin 7.5
ubiquinol 7.5
3,5-T2 7.4
COX 7.1
R207910 7.1
more...