Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.9.3.1 (
cytochrome oxidase
)
8,822
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
cytochrome
866
cytochrome aa3
865
cytochrome c oxidase
816
Mol
759
cytochrome c
746
ATP
627
Sep
574
AED
423
NADH
422
cytochrome b
311
citrate synthase
274
ATPase
265
catalase
194
ADP
187
lactate dehydrogenase
184
superoxide dismutase
179
hemoglobin
161
Cytochrome c
149
peroxidase
137
ATP synthase
136
reductase
135
NADH dehydrogenase
127
cryptic
126
COX
122
NAD
119
tRNA
116
polypeptide
111
ubiquinone
109
nitric oxide synthase
105
COI
105
acid phosphatase
100
oxidoreductase
99
acetylcholinesterase
98
EPR
97
malate dehydrogenase
97
insulin
93
membrane-bound
90
axonal
78
Pseudomonas
75
NADPH
75
more...
Disease
Alzheimer's disease
154
ischemia
143
cold
103
Parkinson's disease
100
cancer
98
Leigh syndrome
92
depression
81
myopathy
72
lactic acidosis
72
mitochondrial disease
70
tumor
69
diabetes
64
GSH
61
stroke
58
cardiomyopathy
53
encephalopathy
46
obesity
43
SDS
43
mitochondrial myopathy
39
epilepsy
38
West
36
Huntington's disease
35
malaria
34
amyotrophic lateral sclerosis
29
hypertension
29
heart failure
29
worms
28
sepsis
28
neuroblastoma
28
mole
27
mole
27
hepatocellular carcinoma
27
dementia
26
sepsis
26
developmental delay
25
cerebral ischemia
24
neuropathy
23
Menkes
21
failure to thrive
20
SEM
20
more...
Symptom
seizures
67
hypotonia
57
weakness
47
ataxia
35
anesthesia
33
ophthalmoplegia
25
collapse
23
fatigue
22
hyperoxia
20
exhaustion
20
starvation
14
hepatomegaly
13
vomiting
13
functional recovery
12
pain
12
dystonia
9
hypothermia
9
lethargy
8
tremor
7
respiratory distress
6
myalgia
6
cerebellar ataxia
6
headache
5
diarrhea
5
memory loss
5
dyspnea
5
cachexia
5
chorea
4
Decreased activity
4
myoclonus
4
thinning
4
nausea
4
hypercapnia
4
dysarthria
4
paresis
3
stigma
3
cyanosis
3
constipation
3
spasticity
3
paraparesis
3
more...
Drug
NADH
434
ascorbate
149
lysine
67
ROS
66
Heme
30
FAD
26
citric acid
20
vitamin E
19
Gel
17
CSF
14
Cardiovasc
13
Ethanol
10
Leaf
9
AZT
9
AZT
9
Methylene blue
9
Nephron
8
caffeine
8
lactose
8
Reserpine
7
Dermatol
7
PCP
6
Glutathione
6
Asn
6
NH3
6
Singular
5
Kenyan
5
NBT
5
Adriamycin
5
ABC
4
ampicillin
4
Senna
4
Senna
4
ICI
4
Vitamin A
4
ALA
4
Atabrine
4
CTX
3
Galactose
3
DNase I
3
more...
Enzyme
cytochrome oxidase
8822
complex I
696
succinate dehydrogenase
640
ATPase
379
diaphorase
340
citrate synthase
281
superoxide dismutase
204
catalase
201
lactate dehydrogenase
199
CPR
195
ATP synthase
181
peroxidase
163
NADH dehydrogenase
128
malate dehydrogenase
114
succinic dehydrogenase
110
acetylcholinesterase
104
acid phosphatase
100
creatine kinase
74
monoamine oxidase
72
NO synthase
70
alkaline phosphatase
66
glutamate dehydrogenase
64
glutamate dehydrogenase
64
NADPH-diaphorase
63
glutamate dehydrogenase
62
pyruvate dehydrogenase
62
phosphofructokinase
58
glucose-6-phosphate dehydrogenase
58
hexokinase
54
isocitrate dehydrogenase
52
pyruvate dehydrogenase
51
isocitrate dehydrogenase
51
pyruvate dehydrogenase
49
pyruvate kinase
47
NQO1
47
caspase-3
43
glutathione peroxidase
42
ceruloplasmin
40
aconitase
39
phosphorylase
39
more...
Compound
oxygen
1422
DNA
1372
ATP
629
Dec
627
cyanide
460
NADH
433
copper
416
glucose
330
water
330
sodium
265
iron
254
nitric oxide
241
calcium
240
ADP
201
CO2
200
phosphate
191
ADP
188
ADP
188
hydrogen
178
glutamate
172
NAD
152
Cytochrome c
149
COX
122
NAD
119
nitrogen
115
Clin
110
ubiquinone
107
COI
107
potassium
98
nicotinamide
93
His
91
H2O2
90
ethanol
89
ubiquinol
85
lysine
80
leucine
80
NADPH
75
NADPH
75
cysteine
72
zinc
72
more...