Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.9.3.1 (cytochrome oxidase)
 8,822 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
cytochrome 866
cytochrome aa3 865
cytochrome c oxidase 816
Mol 759
cytochrome c 746
ATP 627
Sep 574
AED 423
NADH 422
cytochrome b 311
citrate synthase 274
ATPase 265
catalase 194
ADP 187
lactate dehydrogenase 184
superoxide dismutase 179
hemoglobin 161
Cytochrome c 149
peroxidase 137
ATP synthase 136
reductase 135
NADH dehydrogenase 127
cryptic 126
COX 122
NAD 119
tRNA 116
polypeptide 111
ubiquinone 109
COI 105
nitric oxide synthase 105
acid phosphatase 100
oxidoreductase 99
acetylcholinesterase 98
malate dehydrogenase 97
EPR 97
insulin 93
membrane-bound 90
axonal 78
Pseudomonas 75
NADPH 75
complex I) 74
membrane protein 73
myoglobin 71
Gen 67
parvalbumin 66
ROS 66
creatine kinase 66
alkaline phosphatase 66
endoplasmic reticulum 65
microsomal 64
glutamate dehydrogenase 63
GSH 61
esterase 58
nov 57
phosphofructokinase 56
CO2 54
hexokinase 54
PGC 53
caspase-3 53
glucose-6-phosphate dehydrogenase 52
fused 49
COII 49
calbindin 49
pyruvate dehydrogenase 49
isocitrate dehydrogenase 48
COX1 47
pyruvate kinase 47
cox1 47
ferrocytochrome c:oxygen oxidoreductase 44
SDS 43
acyl-CoA oxidase 42
glutathione peroxidase 41
dimeric 40
proton pump 40
peroxisome proliferator-activated receptor 39
GABA 39
glucose-6-phosphatase 38
aconitase 37
uncoupling protein 37
AMP 36
NMR 35
mitochondrial transcription factor A 34
cytochrome bc1 34
flavoprotein 33
adenosine triphosphatase 33
NAD+ 32
CA1 32
GDP 32
SURF1 32
ceruloplasmin 31
amyloid precursor protein 30
COX IV 29
aspartate aminotransferase 29
F1-ATPase 29
diaphorase 29
COX2 28
olfactory 27
MELAS 27
MRI 27
Chlamydomonas 27
FAD 26
NADP 26
cardiac muscle 26
Bcl-2 26
cytochrome P-450 26
beta-glucuronidase 24
antioxidant enzyme 24
CA3 24
ND1 24
CO1 23
cytokine 23
lipopolysaccharide 23
SDH 23
p53 23
MnSOD 22
OXPHOS 22
SOD 22
COXIV 22
LDH 22
spermatozoa 21
alpha-ketoglutarate dehydrogenase 21
outer mitochondrial membrane 21
glutamic acid decarboxylase 20
fumarase 20
COXII 20
inducible nitric oxide synthase 20
glutathione reductase 20
unknown function 20
apoE 20
serum albumin 20
5'-nucleotidase 19
gut 19
COX4 19
Mem 19
NADH-ubiquinone oxidoreductase 19
VIII 19
tyrosine hydroxylase 18
Catalase 18
COX10 18
myosin heavy chain 18
dihydrofolate reductase 18
thyroid hormone 18
peroxisome proliferator-activated receptor gamma 18
collagen 18
IVA 18
myosin 18
follistatin 18
TCA 17
cytochrome b5 17
calretinin 17
TFAM 17
xanthine oxidase 17
cytochrome oxidase subunit I 17
manganese superoxide dismutase 17
substance P 17
mitochondrial ATPase 17
NMDA receptor 16
Pol 16
PCC 16
uncoupling protein 1 16
more...
Disease
Alzheimer's disease 154
ischemia 143
cold 103
Parkinson's disease 100
cancer 98
Leigh syndrome 92
depression 81
lactic acidosis 72
myopathy 72
mitochondrial disease 70
tumor 69
diabetes 64
GSH 61
stroke 58
cardiomyopathy 53
encephalopathy 46
SDS 43
obesity 43
mitochondrial myopathy 39
epilepsy 38
West 36
Huntington's disease 35
malaria 34
hypertension 29
heart failure 29
amyotrophic lateral sclerosis 29
worms 28
sepsis 28
neuroblastoma 28
mole 27
hepatocellular carcinoma 27
mole 27
sepsis 26
dementia 26
developmental delay 25
cerebral ischemia 24
neuropathy 23
Menkes 21
anemia 20
SEM 20
failure to thrive 20
multiple sclerosis 19
pheochromocytoma 19
hypothyroidism 18
Brown 18
IVA 18
fits 18
hypertrophic cardiomyopathy 18
cognitive impairment 18
PCC 17
hyperglycemia 16
iron deficiency 16
NAME 16
schizophrenia 16
MELAS 16
cholera 16
type 2 diabetes 15
Kearns-Sayre syndrome 15
Echinococcus 15
OPA1 15
carcinoma 14
optic atrophy 14
respiratory failure 14
myocardial ischemia 14
HIV 14
MELAS 14
strabismus 13
cataract 12
cirrhosis 12
lice 12
mitochondrial encephalomyopathy 12
myocardial infarction 12
malnutrition 12
coma 12
peripheral neuropathy 12
hypoglycemia 11
cardiovascular disease 11
deafness 11
enzyme deficiency 11
mental retardation 11
Copper deficiency 11
Friedreich's ataxia 11
parkinsonism 11
confusion 11
leukodystrophy 10
glioma 10
MERRF 10
infectious diseases 10
myiasis 10
Mitchell 10
mental retardation 10
immunodeficiency 10
virus infection 10
liver disease 9
Evans 9
proteinuria 9
leukemia 9
abdominal aortic aneurysm 9
hyperphagia 9
Pineal 9
infestation 9
breast cancer 9
fatty liver 9
MRS 9
coronary artery disease 9
hepatic encephalopathy 9
muscular atrophy 9
prolapse 8
wasting 8
metabolic disorder 8
AAA 8
Leber's hereditary optic neuropathy 8
memory impairment 8
Chagas 8
glucose intolerance 8
amblyopia 8
carcinogenesis 8
macular degeneration 8
IBM 8
brain atrophy 8
sensorineural hearing loss 8
dilated cardiomyopathy 8
Infection 8
osteoporosis 8
hyperthyroidism 7
pulmonary hypertension 7
leukoencephalopathy 7
dengue 7
meningitis 7
blindness 7
Edwards 7
brain dysfunction 7
Alpers 7
congestive heart failure 7
tumorigenesis 7
autism 7
Blocking 7
sudden infant death syndrome 7
pulmonary edema 7
major depressive disorder 7
chronic obstructive pulmonary disease 7
status epilepticus 7
atherosclerosis 7
tuberculosis 6
Klebsiella 6
nystagmus 6
PMS 6
glioblastoma 6
hookworm 6
Fanconi 6
neurological disease 6
leishmaniasis 6
metabolic syndrome 6
genetic disorder 6
bipolar disorder 6
PCP 6
tumor progression 6
renal disease 6
renal failure 6
subarachnoid hemorrhage 6
more...
Symptom
seizures 67
hypotonia 57
weakness 47
ataxia 35
anesthesia 33
ophthalmoplegia 25
collapse 23
fatigue 22
exhaustion 20
hyperoxia 20
starvation 14
vomiting 13
hepatomegaly 13
functional recovery 12
pain 12
dystonia 9
hypothermia 9
lethargy 8
tremor 7
respiratory distress 6
cerebellar ataxia 6
myalgia 6
diarrhea 5
headache 5
memory loss 5
dyspnea 5
cachexia 5
dysarthria 4
thinning 4
myoclonus 4
hypercapnia 4
nausea 4
chorea 4
Decreased activity 4
constipation 3
cyanosis 3
paresis 3
spasticity 3
stigma 3
paraparesis 3
hangover 3
Exercise intolerance 3
anorexia 3
Anoxia 2
torticollis 2
sleepiness 2
dizziness 2
Excitability 2
tachypnea 2
acute stress 2
Wind 2
incoordination 2
Mills 2
splenomegaly 2
agitation 2
neurological disability 2
apathy 2
angina 2
pallor 2
cough 1
ketonuria 1
restriction of respiration 1
DNA marker 1
despair 1
polyuria 1
asthenia 1
Ill 1
regurgitation 1
dysosmia 1
insomnia 1
fasciculation 1
acidity 1
abnormal gait 1
erythema 1
Drugged 1
vertigo 1
analgesia 1
masculinization 1
prostration 1
Hudson 1
Reticulocytosis 1
Extrapyramidal symptoms 1
male subfertility 1
autodigestion 1
hepatosplenomegaly 1
hemiplegia 1
breath holding 1
spasm 1
twitching 1
overweight 1
Deafferentation 1
chills 1
Angioscotoma 1
hypocapnia 1
labored breathing 1
photophobia 1
giddiness 1
giddiness 1
clonus 1
physical appearance 1
hypertonia 1
urethral discharge 1
eds 1
anosmia 1
Depressive symptoms 1
Drug
NADH 434
ascorbate 149
lysine 67
ROS 66
Heme 30
FAD 26
citric acid 20
vitamin E 19
Gel 17
CSF 14
Cardiovasc 13
Ethanol 10
AZT 9
Leaf 9
Methylene blue 9
AZT 9
lactose 8
Nephron 8
caffeine 8
Reserpine 7
Dermatol 7
NH3 6
Glutathione 6
PCP 6
Asn 6
Adriamycin 5
Kenyan 5
Singular 5
NBT 5
ALA 4
Senna 4
ABC 4
ICI 4
Vitamin A 4
ampicillin 4
Atabrine 4
Senna 4
Galactose 3
Indomethacin 3
p75 3
Acacia 3
Parkin 3
Glucagon 3
Vitamin K 3
CTX 3
Propofol 3
THF 3
Digenea 3
Nitric Oxide 3
niacin 3
DNase I 3
pyridoxal phosphate 3
Monit 3
Fragment 3
Retinoic acid 3
Parkin 3
DHT 3
DHT 3
Simvastatin 2
CaCl2 2
Doxycycline 2
Vitamin B12 2
Naftidrofuryl 2
Vitamin E 2
Trifluoperazine 2
Coral 2
Adenosine triphosphate 2
Papaverine 2
ETS 2
BH4 2
EE2 2
Fructose 2
CaCl2 2
CaCl2 2
Cytidine 2
MAP 2
Frontal 2
Riboflavin 2
Retinoic Acid 2
URF 2
CDP 2
ETA 2
Alanine 2
Fraction 2
ADM 2
Portal 2
MRC 2
Nephron 2
TTC 2
Isotretinoin 2
Flavin 2
Spectrum 1
Protamine sulfate 1
Viagra 1
Lovastatin 1
Atropine 1
Viagra 1
Codeine 1
PTC 1
Alliance 1
Angiotensin II 1
CTX 1
PPA 1
Ranitidine 1
Emodin 1
LCM 1
Glycyrrhiza 1
Ferumoxides 1
Tween 40 1
Estrogens 1
CAM 1
7-Nitroindazole 1
Diphenhydramine 1
Fenbendazole 1
Lactose 1
ISP 1
Taxol 1
Capsicum 1
MEA 1
Ginseng 1
Duroquinone 1
CTA 1
Zinc sulfate 1
3,4-Dihydroxyphenylalanine 1
Everolimus 1
Doyle 1
Bezafibrate 1
OTC 1
Zinc sulfate 1
Lead acetate 1
Ketoconazole 1
Fipronil 1
Spectrum 1
EHDP 1
CTT 1
Clofibrate 1
TMS 1
L-tyrosine 1
DPA 1
Caspofungin 1
Hyperforin 1
Sodium thiosulfate 1
Codeine 1
Sodium nitroprusside 1
Cobalamin 1
Cantor 1
Sodium Nitroprusside 1
SMP 1
OTC 1
Perindopril 1
LCM 1
Sodium ascorbate 1
Mirtazapine 1
Gastro 1
Monensin 1
Apomorphine 1
ddI 1
ZnO 1
Vitamin B 1
Lugol 1
more...
Enzyme
cytochrome oxidase 8822
complex I 696
succinate dehydrogenase 640
ATPase 379
diaphorase 340
citrate synthase 281
superoxide dismutase 204
catalase 201
lactate dehydrogenase 199
CPR 195
ATP synthase 181
peroxidase 163
NADH dehydrogenase 128
malate dehydrogenase 114
succinic dehydrogenase 110
acetylcholinesterase 104
acid phosphatase 100
creatine kinase 74
monoamine oxidase 72
NO synthase 70
alkaline phosphatase 66
glutamate dehydrogenase 64
glutamate dehydrogenase 64
NADPH-diaphorase 63
glutamate dehydrogenase 62
pyruvate dehydrogenase 62
glucose-6-phosphate dehydrogenase 58
phosphofructokinase 58
hexokinase 54
isocitrate dehydrogenase 52
isocitrate dehydrogenase 51
pyruvate dehydrogenase 51
pyruvate dehydrogenase 49
pyruvate kinase 47
NQO1 47
caspase-3 43
glutathione peroxidase 42
ceruloplasmin 40
phosphorylase 39
aconitase 39
glucose-6-phosphatase 38
diaphorase 36
aspartate aminotransferase 35
nitrite reductase 30
nitrite reductase 29
glycerol-3-phosphate dehydrogenase 29
nitrite reductase 29
ubiquinol-cytochrome c oxidoreductase 29
glycerol-3-phosphate dehydrogenase 28
alpha-ketoglutarate dehydrogenase 27
AMP-activated protein kinase 26
protein kinase 25
beta-glucuronidase 23
5'-nucleotidase 22
glutathione reductase 21
cholinesterase 21
fumarase 21
beta-hydroxybutyrate dehydrogenase 20
glyceraldehyde-3-phosphate dehydrogenase 20
alanine aminotransferase 20
CPT 20
dihydrofolate reductase 18
cytochrome c peroxidase 18
3-hydroxyacyl-CoA dehydrogenase 18
xanthine oxidase 18
tyrosine hydroxylase 18
mitogen-activated protein kinase 17
beta-galactosidase 17
glyceraldehyde-3-phosphate dehydrogenase 17
glutathione S-transferase 17
NOS 16
choline acetyltransferase 16
glyceraldehyde-3-phosphate dehydrogenase 16
3-hydroxyacyl-CoA dehydrogenase 15
reverse transcriptase 15
NADPH oxidase 15
glyceraldehyde-3-phosphate dehydrogenase 15
alcohol dehydrogenase 15
nitrate reductase 14
NADPH oxidase 14
acyl-CoA dehydrogenase 14
glyceraldehyde-3-phosphate dehydrogenase 14
guanylate cyclase 14
nitrate reductase 13
nitrate reductase 13
lipase 13
lipoprotein lipase 13
AMPK 13
nitrate reductase 13
nitrate reductase 13
leucine aminopeptidase 13
nitrate reductase 13
proteasome 13
RNA polymerase 13
AMPK 13
ALA synthase 12
ferrochelatase 12
tyrosinase 12
caspase-9 12
RNase 12
urease 12
protein kinase C 12
adenylate kinase 12
aldolase 12
urease 12
ACE 12
endonuclease 12
6-phosphogluconate dehydrogenase 12
6-phosphogluconate dehydrogenase 12
nucleotidase 12
rhodanese 11
trypsin 11
DNA polymerase 11
carbonic anhydrase 11
nitrous oxide reductase 11
lysozyme 10
phosphoglucose isomerase 10
PDH 10
nitrogenase 10
hydrogenase 10
glutamate decarboxylase 10
cathepsin D 10
hydrogenase 10
ERK 9
MDH 9
RNase 9
calcineurin 9
MDH 9
DNase 8
CAD 8
CAD 8
CAD 8
dopamine beta-hydroxylase 8
MPP 8
ornithine transcarbamylase 8
adenylate cyclase 8
uricase 8
fumarate reductase 8
demethylase 8
enolase 7
phosphoenolpyruvate carboxykinase 7
luciferase 7
phosphoenolpyruvate carboxykinase 7
hexosaminidase 7
PARP 7
phosphoenolpyruvate carboxykinase 7
sulfatase 7
alpha-glucosidase 7
pyruvate carboxylase 7
BAT 7
phosphoglucomutase 7
glycolate oxidase 7
arginine kinase 7
beta-glucosidase 7
alpha-mannosidase 7
soluble epoxide hydrolase 6
ADPase 6
PCP 6
phospholipase A2 6
CPT 6
more...
Compound
oxygen 1422
DNA 1372
ATP 629
Dec 627
cyanide 460
NADH 433
copper 416
glucose 330
water 330
sodium 265
iron 254
nitric oxide 241
calcium 240
ADP 201
CO2 200
phosphate 191
ADP 188
ADP 188
hydrogen 178
glutamate 172
NAD 152
Cytochrome c 149
COX 122
NAD 119
nitrogen 115
Clin 110
ubiquinone 107
COI 107
potassium 98
nicotinamide 93
His 91
H2O2 90
ethanol 89
ubiquinol 85
leucine 80
lysine 80
NADPH 75
NADPH 75
cysteine 72
zinc 72
sulfate 71
GSH 70
GSH 70
methionine 69
arginine 69
Cereb 64
nitrate 62
acetate 60
galactose 57
salt 54
Cyt 53
tyrosine 53
SDS 53
H2S 52
Triton X-100 51
succinic acid 50
alanine 46
bromide 43
ammonium 42
glycerol 41
tryptophan 40
GABA 40
tryptophan 40
CoA 40
tryptophan 39
GABA 39
tryptophan 39
AMP 38
H2S 37
TMPD 37
NADP 36
urea 35
GDP 35
phosphocreatine 34
manganese 32
Heme 31
proline 31
serine 30
2-oxoglutarate 29
Phe 27
Mg2+ 27
FAD 26
ammonia 26
noradrenaline 26
silver 26
Ile 25
gamma-aminobutyric acid 25
uridine 25
cobalt 25
threonine 24
methanol 24
acrylamide 23
L-carnitine 23
phosphorus 22
pyridine 22
MTT 22
coenzyme Q10 21
Cardiol 21
superoxide radical 21
EDTA 20
TCA 20
EDTA 20
pentose 19
5-HT 19
Melatonin 19
pentose 19
Rotenone 19
Asp 19
pentose 19
glutamine 19
pentose 19
Neuronal 18
NMDA 18
phenazine 18
NH2 18
glucose-6-phosphate 17
valine 17
Cu(II) 17
DEAE 16
PEG 16
creatinine 16
iodine 15
isocitrate 15
CoQ 15
hexose 15
TNF 15
hexose 15
aluminum 15
Gly 15
hexose 15
hexose 15
isoleucine 15
cadmium 15
DNP 15
MPTP 15
Lactate 15
Insulin 14
dicarboxylic acid 14
heptyl 14
heptyl 14
alcohol dehydrogenase 14
isoleucine 13
hydroxylamine 13
hydroxylamine 13
aldehyde 13
DAB 13
formaldehyde 13
CAM 13
glutamic acid 13
cGMP 13
phenol 12
CAT 12
carbonate 12
N-acetylcysteine 12
CAT 12
Yellow 12
NO3 12
selenium 12
cAMP 12
CAT 12
more...