Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.8.1.4 (diaphorase)
 2,754 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
CGI-49 13.5
diaphorase 13.5
lipoamide dehydrogenase 13.3
SH3 domain-binding glutamic acid-rich-like protein 3 12.5
complement Factor H-related protein 1 12.5
Myosin light chain 3 12.5
solute carrier family 25 member 19 12.5
lipoamide 12.2
Diaphorase 12.1
troponin I type 3 11.9
DLDH 11.9
dihydrolipoamide acetyltransferase 11.7
lipoic acid-containing protein 11.5
70kD) 11.5
DRC2 11.2
dihydrolipoamide succinyltransferase 11.1
E3BP 11.0
pdhB 11.0
KGDHC 11.0
Glycine synthase 10.9
lat1 10.9
tubulin alpha-1 chain 10.7
GIN1 10.7
Nucleoside diphosphokinase 10.7
neuronal tropomodulin 10.7
NADH2 10.7
DIA1 10.6
neurofilament triplet L protein 10.5
NADH diaphorase 10.4
protein inhibitor of neuronal nitric oxide synthase 10.3
GluR4c 10.3
aflatoxin B1-aldehyde reductase 10.2
DRS1 10.2
Lipoyltransferase 10.2
STARD6 10.2
2-oxoglutarate dehydrogenase 10.2
pyruvate dehydrogenase complex 10.1
LIPT1 10.0
cvHSP 10.0
LC8a 10.0
CHED 10.0
IMMT 10.0
iron-sulfur protein 3 10.0
alpha-ketoglutarate dehydrogenase 10.0
NADPH2 9.9
DHTKD1 9.9
BCKDH 9.9
ASAL 9.8
E2k 9.8
fructose-bisphosphate aldolase C 9.8
Argininosuccinate synthetase 9.7
succinate dehydrogenase flavoprotein subunit 9.7
alpha 1 collagen 9.6
Malic dehydrogenase 9.6
PDHA 9.5
PDHB 9.5
E1 alpha 9.4
MTND1 9.4
aconitase 2 9.4
H-protein 9.4
NMO1 9.3
Chloride intracellular channel protein 1 9.2
Pyruvate dehydrogenase 9.2
pyruvate dehydrogenase 9.2
BOLA3 9.2
REM1 9.2
PDHC 9.1
mu-crystallin 9.1
PRMT9 9.0
glycine decarboxylase 9.0
UDP-glucuronic acid decarboxylase 9.0
Succinic dehydrogenase 8.9
septin 2 8.9
FADH2 8.9
NADH-coenzyme Q reductase 8.9
ADCY8 8.9
MAPK4 8.9
steroid dehydrogenase-like protein 8.9
QR1 8.9
protein X 8.8
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Disease
Phosphoenolpyruvate carboxykinase deficiency 13.5
Lipoamide dehydrogenase deficiency 11.5
CHED 9.9
PDH deficiency 9.0
vitamin B deficiency 9.0
Lissauer 8.4
Bordetella infection 8.4
Persistent pulmonary hypertension 8.1
DTD 8.0
Reflux nephropathy 8.0
DIA 7.8
CGD 7.3
Ileum 7.3
ANM 7.3
erythrasma 7.2
stage I breast cancer 7.1
cardiosclerosis 6.9
Microangiopathy 6.9
CBS deficiency 6.8
Klebs 6.7
Chronic progressive external ophthalmoplegia 6.7
glutaric aciduria 6.6
favism 6.5
Friedreich's ataxia 6.5
hyperglycinemia 6.3
keratocyst 6.3
SGS 6.3
Retinal ischemia 6.3
lymphoblastoma 6.2
PDC 6.2
methemoglobinemia 6.2
alcoholic cardiomyopathy 6.1
PC deficiency 6.1
Spinal cord ischemia 6.1
Reye 6.1
Lip 6.1
SGS 5.9
Choroid 5.9
Choroid 5.9
PAPA 5.8
Leigh syndrome 5.8
GCE 5.8
Gull 5.8
propionic acidemia 5.7
diabetic hyperglycemia 5.6
acrocyanosis 5.6
liver infection 5.6
Rotor 5.6
maple syrup urine disease 5.6
Enzyme inhibition 5.5
GHD 5.5
lactic acidosis 5.5
Bardet-Biedl syndrome 5.4
centronuclear myopathy 5.3
testicular dysfunction 5.3
audiogenic seizure 5.2
Copper deficiency 5.2
myeloblastosis 5.1
LAD 5.1
HTL 5.0
spindle cell sarcoma 5.0
chronic rhinitis 5.0
SD1 5.0
farmer's lung 5.0
cerebral thrombosis 4.9
NAME 4.9
nutritional disorder 4.9
PHS 4.9
galactosemia 4.8
anal atresia 4.8
chronic granulomatous disease 4.7
enzyme deficiency 4.7
Infestation 4.6
clonorchiasis 4.6
MELAS 4.6
mastopathy 4.6
neonatal asphyxia 4.5
Diaphragm 4.5
PCC 4.4
mitochondrial myopathy 4.4
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Symptom
Decreased activity 4.4
ketonuria 4.4
orofacial pain 3.6
eds 3.4
urinary frequency 3.4
abnormal gait 3.4
nasal congestion 3.3
chronic constipation 3.2
tonic-clonic seizure 3.1
hypotonia 3.0
anosmia 2.9
incoordination 2.7
memory loss 2.7
twitching 2.5
ataxia 2.3
pallor 2.2
tachypnea 2.2
functional recovery 2.1
ophthalmoplegia 1.8
starvation 1.7
cyanosis 1.6
anorexia 1.3
acute stress 1.3
constipation 1.2
lethargy 1.0
seizures 1.0
hypothermia 1.0
hepatomegaly 1.0
hemoptysis 0.9
weakness 0.9
fatigue 0.8
spasticity 0.8
myalgia 0.8
arthralgia 0.7
dystonia 0.5
collapse 0.3
respiratory distress 0.2
thinning 0.0
agitation -0.1
sleepiness -0.1
stigma -0.2
pain -0.3
analgesia -0.3
acidity -0.4
anesthesia -0.4
vomiting -0.5
nausea -1.0
dyspnea -1.3
headache -1.3
abdominal pain -1.4
Drug
Cocarboxylase 10.7
FAD 8.5
NADH 8.4
Atabrine 7.6
Phenprocoumon 7.0
Flavin 6.7
Trypanothione 6.5
Fenbendazole 6.2
NBT 6.1
Vardenafil 6.1
Ethylenediamine 5.7
Kainic acid 5.7
Trifluoperazine 5.7
Cibacron Blue 5.6
Riboflavin 5.5
Photofrin II 5.5
Vitamin K 5.4
DFP 5.2
Sodium valproate 5.2
Captopril 4.9
pyridoxal phosphate 4.8
Aminoguanidine 4.8
L-tyrosine 4.6
Sodium nitroprusside 4.6
Clofibrate 4.4
GHRP 4.4
Apomorphine 4.2
Methylene blue 4.2
Nitric Oxide 4.2
AGG 3.9
Gastro 3.7
ascorbate 3.5
Glutathione 3.4
citric acid 3.4
Fraction 3.2
Amiloride 2.9
MgSO4 2.9
Heme 2.9
TAC 2.8
Ginseng 2.8
Simvastatin 2.8
PTC 2.7
Amiloride 2.7
Gel 2.6
niacin 2.6
lysine 2.6
Ethanol 2.6
THF 2.5
Paraffin 2.4
Glycerol 2.3
Fragment 2.3
TAT 2.3
Clonidine 2.3
Ouabain 2.2
HCG 2.1
Bifidobacterium 2.0
Taxol 1.9
ROS 1.8
Vitamin E 1.8
PCP 1.6
p75 1.6
Portal 1.5
caffeine 1.4
Adriamycin 1.3
Albumin 1.3
Mutagen 1.0
EE2 0.6
DNase I 0.5
vitamin E 0.4
Nephron 0.4
CTX 0.2
TiO2 0.0
Asn -0.0
IL-2 -0.3
MAP -0.4
lactose -0.5
Leaf -0.9
Cardiovasc -2.1
Dermatol -3.5
Enzyme
diaphorase 13.5
4NQO reductase 13.5
malate-lactate transhydrogenase 13.5
asparagusate dehydrogenase 13.5
2-methylisocitrate dehydratase 12.5
NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase 12.5
NADPH-diaphorase 12.5
ferric leghemoglobin reductase 12.2
lipoate acetyltransferase 12.0
dihydrolipoyl transacylase 12.0
bis-gamma-glutamylcystine reductase 11.9
diaphorase 11.9
NQO1 11.8
dihydrolipoamide succinyltransferase 11.7
EC 1.1.1.108 11.5
12alpha-hydroxysteroid dehydrogenase 11.2
p-benzoquinone reductase 11.2
2-oxoisovalerate dehydrogenase 11.2
D-sorbitol dehydrogenase 10.6
4-N-trimethylaminobutyraldehyde dehydrogenase 10.3
bidirectional hydrogenase 10.2
2-oxoglutarate decarboxylase 10.2
mercuric reductase 10.1
NAD+ synthetase 10.0
diacetyl reductase 10.0
alpha-ketoglutarate dehydrogenase 9.9
4-hydroxyproline 2-epimerase 9.9
glycine reductase 9.9
coenzyme A disulfide reductase 9.8
branched-chain alpha-keto acid dehydrogenase 9.8
adrenodoxin reductase 9.7
proteasome ATPase 9.5
PdxJ 9.5
4-hydroxybutyrate dehydrogenase 9.5
BCKA 9.4
pyruvate dehydrogenase 9.4
pyruvate dehydrogenase 9.4
T-protein 9.3
pyruvate dehydrogenase 9.3
nicotinic acid hydroxylase 9.2
glutathione oxidase 9.2
acylcarnitine hydrolase 9.1
D-galactose dehydrogenase 9.1
allantoate amidohydrolase 8.9
trypanothione reductase 8.8
glycine decarboxylase 8.8
NADH peroxidase 8.8
glycine dehydrogenase 8.8
glycine dehydrogenase 8.8
pyruvate decarboxylase 8.7
chorismate synthase 8.7
3beta-HSDH 8.7
fructose-6-phosphate phosphoketolase 8.6
NADH-cytochrome b5 reductase 8.6
beta-hydroxybutyrate dehydrogenase 8.5
EC 1.1.1.47 8.5
oxoglutarate dehydrogenase 8.5
hydroxyprostaglandin dehydrogenase 8.5
organomercurial lyase 8.3
acetate CoA-transferase 8.3
oligoribonuclease 8.3
IMP cyclohydrolase 8.2
nicotinamide adenine dinucleotide glycohydrolase 8.2
glycine dehydrogenase 8.1
transhydrogenase 8.1
butyrate kinase 8.1
NAD+ kinase 8.1
pyruvate dehydrogenase phosphatase 8.0
phosphotransbutyrylase 8.0
desulfinase 8.0
dihydrodipicolinate reductase 7.9
leucine dehydrogenase 7.9
EC 1.7.7.1 7.9
PTR1 7.8
glycerol-3-phosphate oxidase 7.8
NAD+ oxidoreductase 7.7
electron transfer flavoprotein dehydrogenase 7.7
sarcosine dehydrogenase 7.7
disulfide reductase 7.7
succinic dehydrogenase 7.6
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Compound
Optochin hydrochloride 13.5
Asparagusate 13.5
S-Methylisothiourea sulfate 13.5
dihydrolipoamide 12.4
1-bromoheptane 12.1
5-Methoxyindole 11.5
CB 1954 11.4
spirost-5-en-3-ol 11.2
Trichloropropene oxide 10.9
2-Fluoroadenine 10.9
TNBT 10.6
EH2 10.3
Menadiol 10.2
Lipozyme 10.1
Dihydrolipoic acid 9.8
DEPA 9.6
S-(carboxymethyl)cysteine 9.3
S-(carboxymethyl)cysteine 9.3
Ferredoxin 9.3
p-Nitrobenzoic acid 9.2
nicotinamide 9.2
DEPA 9.2
NMOR 9.1
L-dopachrome 9.0
Fe(CN)3 8.9
Nitrofuran 8.9
1,3-Dinitrobenzene 8.7
2-nitroso-1-naphthol 8.6
Ferricyanide 8.5
FAD 8.5
Chorismate 8.4
2-methylcitric acid 8.4
NADH 8.4
2-hydroxybutanoic acid 8.3
2-oxoadipate 8.3
2,6-dichlorophenol 8.2
7-Ethoxyresorufin 8.2
Chicago Sky Blue 6B 8.2
Avertin 8.1
DCIP 8.1
NADPH 8.0
NADPH 8.0
Pyrithiamine 8.0
2-hydroxybutanoic acid 8.0
Vitamin K epoxide 7.9
BHC 7.9
NADP 7.9
hydroxytyramine 7.8
Ethylparaben 7.8
Ferrocyanide 7.8
Phenanthrenequinone 7.7
3-buten-2-one 7.6
DPN 7.6
3-buten-2-one 7.5
NAD 7.5
NAD 7.4
D-Arginine 7.4
Acetyl phosphate 7.3
C3H7NO 7.2
FMNH 7.2
Nifurtimox 7.1
Molybdenum cofactor 7.1
allantoate 7.1
C3H7NO 7.0
N'-methylnicotinamide 7.0
1,2-dithiolane 7.0
Phenothiazine 7.0
FCB 7.0
Diethyl pyrocarbonate 7.0
Lip 7.0
DTE 6.9
SCMC 6.9
1,2,4-benzotriazine 6.9
Trp-P-2 6.9
Dehydroascorbic acid 6.9
Mercaptopropionic acid 6.9
Phenylarsine oxide 6.8
Copper sulfate 6.8
FMN 6.7
ethyl formate 6.7
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