Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.8.1.4 (diaphorase)
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Human Gene/Protein
CGI-49 13.5
diaphorase 13.5
lipoamide dehydrogenase 13.3
complement Factor H-related protein 1 12.5
SH3 domain-binding glutamic acid-rich-like protein 3 12.5
Myosin light chain 3 12.5
solute carrier family 25 member 19 12.5
lipoamide 12.2
Diaphorase 12.1
DLDH 11.9
troponin I type 3 11.9
dihydrolipoamide acetyltransferase 11.7
70kD) 11.5
lipoic acid-containing protein 11.5
DRC2 11.2
dihydrolipoamide succinyltransferase 11.1
E3BP 11.0
pdhB 11.0
KGDHC 11.0
lat1 10.9
more...
Disease
Phosphoenolpyruvate carboxykinase deficiency 13.5
Lipoamide dehydrogenase deficiency 11.5
CHED 9.9
PDH deficiency 9.0
vitamin B deficiency 9.0
Lissauer 8.4
Bordetella infection 8.4
Persistent pulmonary hypertension 8.1
Reflux nephropathy 8.0
DTD 8.0
DIA 7.8
CGD 7.3
Ileum 7.3
ANM 7.3
erythrasma 7.2
stage I breast cancer 7.1
cardiosclerosis 6.9
Microangiopathy 6.9
CBS deficiency 6.8
Klebs 6.7
more...
Symptom
Decreased activity 4.4
ketonuria 4.4
orofacial pain 3.6
eds 3.4
urinary frequency 3.4
abnormal gait 3.4
nasal congestion 3.3
chronic constipation 3.2
tonic-clonic seizure 3.1
hypotonia 3.0
anosmia 2.9
incoordination 2.7
memory loss 2.7
twitching 2.5
ataxia 2.3
pallor 2.2
tachypnea 2.2
functional recovery 2.1
ophthalmoplegia 1.8
starvation 1.7
more...
Drug
Cocarboxylase 10.7
FAD 8.5
NADH 8.4
Atabrine 7.6
Phenprocoumon 7.0
Flavin 6.7
Trypanothione 6.5
Fenbendazole 6.2
NBT 6.1
Vardenafil 6.1
Ethylenediamine 5.7
Kainic acid 5.7
Trifluoperazine 5.7
Cibacron Blue 5.6
Riboflavin 5.5
Photofrin II 5.5
Vitamin K 5.4
DFP 5.2
Sodium valproate 5.2
Captopril 4.9
more...
Enzyme
asparagusate dehydrogenase 13.5
diaphorase 13.5
malate-lactate transhydrogenase 13.5
4NQO reductase 13.5
NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase 12.5
2-methylisocitrate dehydratase 12.5
NADPH-diaphorase 12.5
ferric leghemoglobin reductase 12.2
lipoate acetyltransferase 12.0
dihydrolipoyl transacylase 12.0
bis-gamma-glutamylcystine reductase 11.9
diaphorase 11.9
NQO1 11.8
dihydrolipoamide succinyltransferase 11.7
EC 1.1.1.108 11.5
2-oxoisovalerate dehydrogenase 11.2
12alpha-hydroxysteroid dehydrogenase 11.2
p-benzoquinone reductase 11.2
D-sorbitol dehydrogenase 10.6
4-N-trimethylaminobutyraldehyde dehydrogenase 10.3
more...
Compound
Asparagusate 13.5
S-Methylisothiourea sulfate 13.5
Optochin hydrochloride 13.5
dihydrolipoamide 12.4
1-bromoheptane 12.1
5-Methoxyindole 11.5
CB 1954 11.4
spirost-5-en-3-ol 11.2
Trichloropropene oxide 10.9
2-Fluoroadenine 10.9
TNBT 10.6
EH2 10.3
Menadiol 10.2
Lipozyme 10.1
Dihydrolipoic acid 9.8
DEPA 9.6
S-(carboxymethyl)cysteine 9.3
S-(carboxymethyl)cysteine 9.3
Ferredoxin 9.3
p-Nitrobenzoic acid 9.2
more...