Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: EC:1.6.99.6 (NADPH oxidase)
10,295 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein NADPH 1187 p47 853 superoxide dismutase 831 Mol 753 ROS 654 Sep 645 catalase 642 p47phox 557 NOX2 498 nitric oxide synthase 473 p22phox 467 angiotensin II 456 p38 419 p22 396 p67 394 cytokine 383 xanthine oxidase 352 MAPK 343 NOX4 341 Ang II 340 inducible nitric oxide synthase 339 TNF 322 lipopolysaccharide 305 ERK1 299 myeloperoxidase 292 p67phox 275 insulin 263 tumor necrosis factor 255 caspase-3 252 NADH 241 ATP 238 GSH 220 DPI 214 membrane-bound 212 collagen 210 peroxidase 206 SOD 203 renin 202 PKC 198 NOX1 194 IL-6 192 GTP 191 ERK 185 JNK 179 cytochrome c 175 glutathione peroxidase 169 p47-phox 167 NADPH oxidase 2 161 cytochrome b 158 eNOS 157 endothelial nitric oxide synthase 153 p67-phox 152 X-linked 152 endoplasmic reticulum 152 p40 146 LPS 141 Rho 136 heme oxygenase-1 133 GTPase 127 PI3K 123 p65 121 cytochrome 118 reductase 118 FAD 117 tyrosine kinase 117 mitogen-activated protein 117 NAD 116 TNF-alpha 115 TLR4 111 extracellular signal-regulated kinase 110 small GTPase 99 ATPase 99 p40phox 99 cyclooxygenase 98 Bcl-2 96 glutathione reductase 92 p38 mitogen-activated protein kinase 91 AT1 91 IL-8 89 flavoprotein 88 more...

Disease hypertension 656 chronic granulomatous disease 505 diabetes 490 atherosclerosis 425 cancer 373 ischemia 268 tumor 227 GSH 220 cardiovascular disease 183 stroke 176 Alzheimer's disease 160 heart failure 152 obesity 145 hyperglycemia 141 immunodeficiency 120 Parkinson's disease 116 NAME 115 diabetic nephropathy 110 type 2 diabetes 99 sepsis 94 ATM 93 sepsis 88 metabolic syndrome 78 renal disease 77 proteinuria 76 myocardial infarction 73 vascular disease 71 carcinogenesis 70 pertussis 69 cerebral ischemia 66 plaque 65 infectious diseases 60 Mycobacterium 58 rheumatoid arthritis 57 SDS 53 arthritis 52 leukemia 52 hepatocellular carcinoma 52 asthma 51 pulmonary hypertension 49 cognitive impairment 47 inflammatory bowel disease 45 HIV 44 glomerulosclerosis 43 Blocking 43 tumor progression 42 myocardial ischemia 42 CGD 42 tuberculosis 41 Infection 40 breast cancer 40 Endothelial dysfunction 40 pneumonia 39 hypercholesterolemia 39 tumorigenesis 38 depression 37 dementia 37 bacterial infection 36 tumor growth 36 colitis 35 neuroblastoma 35 adenocarcinoma 34 Epstein 34 liver fibrosis 33 type 1 diabetes 33 melanoma 33 cold 32 multiple sclerosis 32 prostate cancer 31 coronary artery disease 31 hyperhomocysteinemia 31 ventricular hypertrophy 30 cystic fibrosis 30 fatty liver 30 chronic obstructive pulmonary disease 29 diabetic retinopathy 29 aspergillosis 28 cardiomyopathy 28 encephalomyelitis 27 carcinoma 26 more...

Symptom pain 43 hyperoxia 30 anesthesia 20 starvation 19 seizures 18 collapse 16 diarrhea 14 respiratory distress 12 functional recovery 8 exhaustion 8 skin damage 8 weakness 8 overweight 7 fatigue 6 angina 4 hypothermia 4 acidity 4 HSA 3 cough 3 splenomegaly 3 Macula 3 cachexia 3 analgesia 3 headache 3 chills 2 chest pain 2 abdominal pain 2 impaired motor coordination 2 thinning 2 acute stress 2 sleepiness 2 hypercapnia 2 Anoxia 1 orofacial pain 1 hyperesthesia 1 insomnia 1 Neuropathic pain 1 colic 1 nausea 1 numbness 1 scaly skin 1 constipation 1 POA 1 incoordination 1 adenitis 1 erythema 1 DNA marker 1 low back pain 1 limb pain 1 dyspnea 1 memory loss 1 hepatosplenomegaly 1 vomiting 1 pelvic pain 1 polyuria 1 cancer pain 1 tachypnea 1 rhinorrhea 1 microbial colonization 1 Noise-induced hearing loss 1 spasm 1 muscle cramps 1 bradykinesia 1

Drug ROS 654 NADH 239 Angiotensin II 139 FAD 117 ascorbate 103 Cardiovasc 62 IFN-gamma 54 vitamin E 45 CSF 39 Indomethacin 38 MAP 35 lysine 34 Heme 28 BH4 25 nitroglycerin 23 Nitric Oxide 22 NBT 22 Ethanol 22 Dermatol 17 Gel 17 Photofrin 15 ETA 13 ICI 12 DNase I 12 Glutathione 12 Leaf 11 IL-2 9 ENT 8 Histamine 8 Capsicum 7 Nebivolol 7 Simvastatin 7 Forskolin 6 Asthma 6 CAM 6 Arsenic trioxide 6 Bifidobacterium 6 caffeine 6 Albumin 6 Propofol 5 ACT 5 p75 5 ALA 5 Aminoguanidine 5 niacin 5 Fluorescein 5 Olmesartan 5 Captopril 5 CoCl2 5 CoCl2 5 TAT 5 ZnCl2 4 Pravastatin 4 Monit 4 Desferal 4 Adenosine triphosphate 4 Vitamin E 4 Asn 4 Desferal 4 Spectrum 4 Glucagon 4 ZnCl2 4 Rosiglitazone 4 G-CSF 4 Fructose 4 TiO2 3 Cibacron Blue 3 Aliskiren 3 IFN-beta 3 Emodin 3 Epigallocatechin 3 Emodin 3 Fenoldopam 3 TAK 3 Valsartan 3 Parkin 3 Tocopherol 3 Alanine 3 Mutagen 3 Rosuvastatin 3 more...

Enzyme NADPH oxidase 10295 NADPH oxidase 10176 superoxide dismutase 980 mitogen-activated protein kinase 948 protein kinase C 680 catalase 658 peroxidase 500 xanthine oxidase 359 protein kinase 303 NO synthase 262 ERK 258 renin 202 caspase-3 192 glutathione peroxidase 178 NADPH-diaphorase 144 phospholipase A2 113 ATPase 111 MEK 107 phospholipase C 100 NOS 100 complex I 96 glutathione reductase 92 phosphatidylinositol 3-kinase 82 phospholipase D 79 diaphorase 72 lactate dehydrogenase 71 ascorbate peroxidase 67 focal adhesion kinase 66 AMP-activated protein kinase 66 glucose-6-phosphate dehydrogenase 61 heme oxygenase 56 CPR 54 ACE 54 caspase-1 52 luciferase 49 thrombin 47 PARP 46 lipoxygenase 46 elastase 41 calcineurin 39 tyrosine hydroxylase 39 phosphoinositide 3-kinase 37 neutrophil elastase 37 AMPK 37 NQO1 35 phosphodiesterase 35 succinate dehydrogenase 33 MAP 33 peroxiredoxin 33 glutathione S-transferase 32 AMPK 31 DCF 30 proteasome 30 IKK 29 thioredoxin reductase 27 NADH dehydrogenase 26 reverse transcriptase 26 alkaline phosphatase 25 caspase-9 25 alanine aminotransferase 24 guanylate cyclase 24 arginase 23 trypsin 23 lysozyme 22 adenylate cyclase 22 xanthine dehydrogenase 22 collagenase 22 diaphorase 20 aspartate aminotransferase 19 glucose oxidase 18 caspase-8 18 6-phosphogluconate dehydrogenase 17 6-phosphogluconate dehydrogenase 17 nitrate reductase 16 nitrate reductase 16 nitrate reductase 16 thyroid peroxidase 16 nitrate reductase 16 demethylase 16 nitrate reductase 16 more...

Compound oxygen 5074 NADPH 1189 NADPH 1187 nitric oxide 859 hydrogen 800 calcium 726 Dec 716 phosphate 632 acetate 616 H2O2 567 glucose 551 DNA 541 nicotinamide 532 Clin 331 sodium 328 TNF 322 cysteine 316 superoxide radical 306 water 294 Phe 280 tyrosine 263 Ang II 253 ATP 240 NADH 240 nitrogen 235 GSH 230 GSH 230 N-acetylcysteine 224 arginine 218 DPI 214 PMA 214 PMA 211 salt 192 GTP 191 Apocynin 180 Angiotensin II 160 iron 155 NADP 146 leucine 139 NAD 125 ethanol 124 sulfate 122 serine 118 FAD 117 NAD 116 diacetate 113 methionine 110 cAMP 110 glutamate 101 aldosterone 99 zinc 90 potassium 87 THP 85 THP 83 Cardiol 79 nitrate 74 cGMP 74 galactose 72 GDP 71 Panam 67 PEG 67 CO2 66 AMP 65 threonine 63 creatinine 61 Tempol 61 ADP 60 cyanide 58 SDS 58 copper 57 ADP 56 ADP 56 GSSG 55 salicylic acid 55 MDA 55 chromate 54 8-OHdG 53 lysine 51 manganese 49 urea 48 more...

---