Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.6.99.6 (
NADPH oxidase
)
10,295
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
NADPH
1187
p47
853
superoxide dismutase
831
Mol
753
ROS
654
Sep
645
catalase
642
p47phox
557
NOX2
498
nitric oxide synthase
473
p22phox
467
angiotensin II
456
p38
419
p22
396
p67
394
cytokine
383
xanthine oxidase
352
MAPK
343
NOX4
341
Ang II
340
inducible nitric oxide synthase
339
TNF
322
lipopolysaccharide
305
ERK1
299
myeloperoxidase
292
p67phox
275
insulin
263
tumor necrosis factor
255
caspase-3
252
NADH
241
ATP
238
GSH
220
DPI
214
membrane-bound
212
collagen
210
peroxidase
206
SOD
203
renin
202
PKC
198
NOX1
194
more...
Disease
hypertension
656
chronic granulomatous disease
505
diabetes
490
atherosclerosis
425
cancer
373
ischemia
268
tumor
227
GSH
220
cardiovascular disease
183
stroke
176
Alzheimer's disease
160
heart failure
152
obesity
145
hyperglycemia
141
immunodeficiency
120
Parkinson's disease
116
NAME
115
diabetic nephropathy
110
type 2 diabetes
99
sepsis
94
ATM
93
sepsis
88
metabolic syndrome
78
renal disease
77
proteinuria
76
myocardial infarction
73
vascular disease
71
carcinogenesis
70
pertussis
69
cerebral ischemia
66
plaque
65
infectious diseases
60
Mycobacterium
58
rheumatoid arthritis
57
SDS
53
hepatocellular carcinoma
52
arthritis
52
leukemia
52
asthma
51
pulmonary hypertension
49
more...
Symptom
pain
43
hyperoxia
30
anesthesia
20
starvation
19
seizures
18
collapse
16
diarrhea
14
respiratory distress
12
weakness
8
exhaustion
8
functional recovery
8
skin damage
8
overweight
7
fatigue
6
angina
4
acidity
4
hypothermia
4
HSA
3
splenomegaly
3
Macula
3
cachexia
3
analgesia
3
cough
3
headache
3
chills
2
chest pain
2
abdominal pain
2
impaired motor coordination
2
thinning
2
acute stress
2
sleepiness
2
hypercapnia
2
Anoxia
1
orofacial pain
1
hyperesthesia
1
insomnia
1
Neuropathic pain
1
colic
1
nausea
1
scaly skin
1
more...
Drug
ROS
654
NADH
239
Angiotensin II
139
FAD
117
ascorbate
103
Cardiovasc
62
IFN-gamma
54
vitamin E
45
CSF
39
Indomethacin
38
MAP
35
lysine
34
Heme
28
BH4
25
nitroglycerin
23
NBT
22
Nitric Oxide
22
Ethanol
22
Gel
17
Dermatol
17
Photofrin
15
ETA
13
ICI
12
DNase I
12
Glutathione
12
Leaf
11
IL-2
9
ENT
8
Histamine
8
Capsicum
7
Nebivolol
7
Simvastatin
7
caffeine
6
Albumin
6
Bifidobacterium
6
Forskolin
6
Arsenic trioxide
6
CAM
6
Asthma
6
Olmesartan
5
more...
Enzyme
NADPH oxidase
10295
NADPH oxidase
10176
superoxide dismutase
980
mitogen-activated protein kinase
948
protein kinase C
680
catalase
658
peroxidase
500
xanthine oxidase
359
protein kinase
303
NO synthase
262
ERK
258
renin
202
caspase-3
192
glutathione peroxidase
178
NADPH-diaphorase
144
phospholipase A2
113
ATPase
111
MEK
107
phospholipase C
100
NOS
100
complex I
96
glutathione reductase
92
phosphatidylinositol 3-kinase
82
phospholipase D
79
diaphorase
72
lactate dehydrogenase
71
ascorbate peroxidase
67
focal adhesion kinase
66
AMP-activated protein kinase
66
glucose-6-phosphate dehydrogenase
61
heme oxygenase
56
ACE
54
CPR
54
caspase-1
52
luciferase
49
thrombin
47
PARP
46
lipoxygenase
46
elastase
41
tyrosine hydroxylase
39
more...
Compound
oxygen
5074
NADPH
1189
NADPH
1187
nitric oxide
859
hydrogen
800
calcium
726
Dec
716
phosphate
632
acetate
616
H2O2
567
glucose
551
DNA
541
nicotinamide
532
Clin
331
sodium
328
TNF
322
cysteine
316
superoxide radical
306
water
294
Phe
280
tyrosine
263
Ang II
253
NADH
240
ATP
240
nitrogen
235
GSH
230
GSH
230
N-acetylcysteine
224
arginine
218
DPI
214
PMA
214
PMA
211
salt
192
GTP
191
Apocynin
180
Angiotensin II
160
iron
155
NADP
146
leucine
139
NAD
125
more...