Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.6.99.6 (NADPH oxidase)
 10,295 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
NADPH 1187
p47 853
superoxide dismutase 831
Mol 753
ROS 654
Sep 645
catalase 642
p47phox 557
NOX2 498
nitric oxide synthase 473
p22phox 467
angiotensin II 456
p38 419
p22 396
p67 394
cytokine 383
xanthine oxidase 352
MAPK 343
NOX4 341
Ang II 340
more...
Disease
hypertension 656
chronic granulomatous disease 505
diabetes 490
atherosclerosis 425
cancer 373
ischemia 268
tumor 227
GSH 220
cardiovascular disease 183
stroke 176
Alzheimer's disease 160
heart failure 152
obesity 145
hyperglycemia 141
immunodeficiency 120
Parkinson's disease 116
NAME 115
diabetic nephropathy 110
type 2 diabetes 99
sepsis 94
more...
Symptom
pain 43
hyperoxia 30
anesthesia 20
starvation 19
seizures 18
collapse 16
diarrhea 14
respiratory distress 12
functional recovery 8
exhaustion 8
skin damage 8
weakness 8
overweight 7
fatigue 6
angina 4
hypothermia 4
acidity 4
analgesia 3
cachexia 3
Macula 3
more...
Drug
ROS 654
NADH 239
Angiotensin II 139
FAD 117
ascorbate 103
Cardiovasc 62
IFN-gamma 54
vitamin E 45
CSF 39
Indomethacin 38
MAP 35
lysine 34
Heme 28
BH4 25
nitroglycerin 23
Nitric Oxide 22
NBT 22
Ethanol 22
Gel 17
Dermatol 17
more...
Enzyme
NADPH oxidase 10295
NADPH oxidase 10176
superoxide dismutase 980
mitogen-activated protein kinase 948
protein kinase C 680
catalase 658
peroxidase 500
xanthine oxidase 359
protein kinase 303
NO synthase 262
ERK 258
renin 202
caspase-3 192
glutathione peroxidase 178
NADPH-diaphorase 144
phospholipase A2 113
ATPase 111
MEK 107
NOS 100
phospholipase C 100
more...
Compound
oxygen 5074
NADPH 1189
NADPH 1187
nitric oxide 859
hydrogen 800
calcium 726
Dec 716
phosphate 632
acetate 616
H2O2 567
glucose 551
DNA 541
nicotinamide 532
Clin 331
sodium 328
TNF 322
cysteine 316
superoxide radical 306
water 294
Phe 280
more...