Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:1.6.99.6 (NADPH oxidase)
10,295 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein NADPH 1187 p47 853 superoxide dismutase 831 Mol 753 ROS 654 Sep 645 catalase 642 p47phox 557 NOX2 498 nitric oxide synthase 473 p22phox 467 angiotensin II 456 p38 419 p22 396 p67 394 cytokine 383 xanthine oxidase 352 MAPK 343 NOX4 341 Ang II 340 inducible nitric oxide synthase 339 TNF 322 lipopolysaccharide 305 ERK1 299 myeloperoxidase 292 p67phox 275 insulin 263 tumor necrosis factor 255 caspase-3 252 NADH 241 ATP 238 GSH 220 DPI 214 membrane-bound 212 collagen 210 peroxidase 206 SOD 203 renin 202 PKC 198 NOX1 194 IL-6 192 GTP 191 ERK 185 JNK 179 cytochrome c 175 glutathione peroxidase 169 p47-phox 167 NADPH oxidase 2 161 cytochrome b 158 eNOS 157 endothelial nitric oxide synthase 153 endoplasmic reticulum 152 p67-phox 152 X-linked 152 p40 146 LPS 141 Rho 136 heme oxygenase-1 133 GTPase 127 PI3K 123 p65 121 reductase 118 cytochrome 118 mitogen-activated protein 117 FAD 117 tyrosine kinase 117 NAD 116 TNF-alpha 115 TLR4 111 extracellular signal-regulated kinase 110 small GTPase 99 ATPase 99 p40phox 99 cyclooxygenase 98 Bcl-2 96 glutathione reductase 92 p38 mitogen-activated protein kinase 91 AT1 91 IL-8 89 IFN 88 flavoprotein 88 antioxidant enzyme 88 CD11b 87 p53 85 fibronectin 84 THP 83 cyclooxygenase-2 83 phosphatidylinositol 3-kinase 82 Nrf2 82 vascular endothelial growth factor 82 CYBB 81 c-Jun 81 AKT 80 AP-1 80 albumin 80 ANG 79 phospholipase D 79 microsomal 78 NADP 77 vascular cell adhesion molecule-1 77 COX-2 76 matrix metalloproteinase 74 phospholipase A2 71 monocyte chemoattractant protein-1 71 p21 70 lactate dehydrogenase 69 GDP 69 erythroid 68 ICAM-1 67 endothelin-1 67 NAC 66 interferon 66 Met 65 interferon-gamma 65 calmodulin 65 interleukin-6 63 AMP 62 tat 62 phosphatase 61 Pseudomonas 59 PLB 58 thioredoxin 58 neuronal nitric oxide synthase 57 granulocyte 57 MAP kinase 57 c-Src 56 ADP 56 epidermal growth factor receptor 56 chemokine 56 protein kinase B 56 MEK 55 dual oxidase 55 adhesion molecule 54 IFN-gamma 54 VEGF 53 SDS 53 MCP-1 53 CYBA 52 RhoA 52 tumor necrosis factor alpha 51 vascular endothelium 51 NADPH oxidase 1 51 glucose-6-phosphate dehydrogenase 50 DUOX1 50 MnSOD 50 mineralocorticoid receptor 50 TLR2 49 gut 49 IL-10 48 cytochrome P-450 48 peroxisome proliferator-activated receptor 47 NOX5 47 thrombin 47 p38MAPK 47 lipoxygenase 45 SOD1 44 smooth muscle actin 44 CD18 44 cytochrome P450 44 DUOX2 44 more...

Disease hypertension 656 chronic granulomatous disease 505 diabetes 490 atherosclerosis 425 cancer 373 ischemia 268 tumor 227 GSH 220 cardiovascular disease 183 stroke 176 Alzheimer's disease 160 heart failure 152 obesity 145 hyperglycemia 141 immunodeficiency 120 Parkinson's disease 116 NAME 115 diabetic nephropathy 110 type 2 diabetes 99 sepsis 94 ATM 93 sepsis 88 metabolic syndrome 78 renal disease 77 proteinuria 76 myocardial infarction 73 vascular disease 71 carcinogenesis 70 pertussis 69 cerebral ischemia 66 plaque 65 infectious diseases 60 Mycobacterium 58 rheumatoid arthritis 57 SDS 53 hepatocellular carcinoma 52 leukemia 52 arthritis 52 asthma 51 pulmonary hypertension 49 cognitive impairment 47 inflammatory bowel disease 45 HIV 44 Blocking 43 glomerulosclerosis 43 tumor progression 42 CGD 42 myocardial ischemia 42 tuberculosis 41 Infection 40 breast cancer 40 Endothelial dysfunction 40 pneumonia 39 hypercholesterolemia 39 tumorigenesis 38 dementia 37 depression 37 bacterial infection 36 tumor growth 36 neuroblastoma 35 colitis 35 adenocarcinoma 34 Epstein 34 type 1 diabetes 33 melanoma 33 liver fibrosis 33 cold 32 multiple sclerosis 32 coronary artery disease 31 prostate cancer 31 hyperhomocysteinemia 31 cystic fibrosis 30 fatty liver 30 ventricular hypertrophy 30 chronic obstructive pulmonary disease 29 diabetic retinopathy 29 aspergillosis 28 cardiomyopathy 28 encephalomyelitis 27 hyperlipidemia 26 renal failure 26 Evans 26 carcinoma 26 systemic lupus erythematosus 25 autoimmune disease 24 diabetic cardiomyopathy 23 heart disease 23 lung cancer 23 colon cancer 22 acute promyelocytic leukemia 22 sickle cell disease 21 influenza 21 pheochromocytoma 21 lung disease 21 obstructive sleep apnea 21 virus infection 21 cirrhosis 21 liver disease 21 dyslipidemia 20 MCF 20 glucose intolerance 19 immune deficiency 19 essential hypertension 19 amyotrophic lateral sclerosis 19 malnutrition 18 retinopathy 18 preeclampsia 18 pulmonary fibrosis 18 erectile dysfunction 17 hyperinsulinemia 16 brain edema 16 genetic disorder 16 lupus 16 hepatic encephalopathy 16 coronary heart disease 16 colorectal cancer 16 cholera 16 leishmaniasis 15 anemia 15 osteoarthritis 15 Chlamydia 15 acute myeloid leukemia 15 lymphoma 14 Barrett's esophagus 14 osteoporosis 14 lupus 14 pancreatitis 14 peritonitis 14 PCC 13 fungal infection 13 renal ischemia 13 G6PD deficiency 13 Crohn's disease 13 pancreatic cancer 13 B-cell lymphoma 13 metastases 13 acute myocardial infarction 13 neutropenia 12 salmonellosis 12 hyperuricemia 12 dermatitis 12 chronic renal failure 12 tularemia 12 chronic myeloid leukemia 12 glioblastoma 11 glioma 11 renal cell carcinoma 11 retinopathy of prematurity 11 FAS 11 epilepsy 11 macular degeneration 11 NOD 11 lung carcinoma 11 Duchenne muscular dystrophy 10 acute pancreatitis 10 subarachnoid hemorrhage 10 status epilepticus 10 MIP 10 idiopathic pulmonary fibrosis 10 arteriosclerosis 10 more...

Symptom pain 43 hyperoxia 30 anesthesia 20 starvation 19 seizures 18 collapse 16 diarrhea 14 respiratory distress 12 functional recovery 8 exhaustion 8 skin damage 8 weakness 8 overweight 7 fatigue 6 angina 4 hypothermia 4 acidity 4 HSA 3 cough 3 splenomegaly 3 Macula 3 cachexia 3 analgesia 3 headache 3 chills 2 chest pain 2 abdominal pain 2 impaired motor coordination 2 thinning 2 acute stress 2 sleepiness 2 hypercapnia 2 Anoxia 1 orofacial pain 1 hyperesthesia 1 insomnia 1 Neuropathic pain 1 colic 1 nausea 1 numbness 1 scaly skin 1 constipation 1 POA 1 incoordination 1 adenitis 1 erythema 1 DNA marker 1 low back pain 1 limb pain 1 dyspnea 1 memory loss 1 hepatosplenomegaly 1 vomiting 1 pelvic pain 1 polyuria 1 cancer pain 1 tachypnea 1 rhinorrhea 1 microbial colonization 1 Noise-induced hearing loss 1 spasm 1 muscle cramps 1 bradykinesia 1

Drug ROS 654 NADH 239 Angiotensin II 139 FAD 117 ascorbate 103 Cardiovasc 62 IFN-gamma 54 vitamin E 45 CSF 39 Indomethacin 38 MAP 35 lysine 34 Heme 28 BH4 25 nitroglycerin 23 Ethanol 22 Nitric Oxide 22 NBT 22 Gel 17 Dermatol 17 Photofrin 15 ETA 13 DNase I 12 ICI 12 Glutathione 12 Leaf 11 IL-2 9 ENT 8 Histamine 8 Capsicum 7 Nebivolol 7 Simvastatin 7 Asthma 6 CAM 6 Albumin 6 Bifidobacterium 6 Arsenic trioxide 6 Forskolin 6 caffeine 6 ACT 5 Olmesartan 5 CoCl2 5 Captopril 5 Fluorescein 5 Propofol 5 p75 5 Aminoguanidine 5 ALA 5 CoCl2 5 TAT 5 niacin 5 Adenosine triphosphate 4 Monit 4 Asn 4 Desferal 4 Glucagon 4 Fructose 4 Rosiglitazone 4 Desferal 4 ZnCl2 4 Spectrum 4 Vitamin E 4 ZnCl2 4 G-CSF 4 Pravastatin 4 Emodin 3 Aliskiren 3 Fenoldopam 3 Cibacron Blue 3 Mutagen 3 TiO2 3 TAK 3 Valsartan 3 Parkin 3 Retinoic acid 3 G418 3 ZnO 3 CaCl2 3 Rosuvastatin 3 CaCl2 3 CaCl2 3 Alanine 3 Emodin 3 IFN-beta 3 Fluorescein 3 Glycyrrhiza 3 Docetaxel 3 Parkin 3 Taxol 3 Tocopherol 3 Nephron 3 Epigallocatechin 3 TAC 2 EPA 2 DEX 2 Phosphatidylserine 2 NAG 2 EE2 2 CCL 2 Ergosterol 2 FeCl3 2 Ouabain 2 L-tyrosine 2 Ginger 2 Vitamin K 2 PCP 2 Erlotinib 2 Cilostazol 2 Ezetimibe 2 Rebamipide 2 Rolipram 2 CYSTEINE 2 Pirfenidone 2 ETS 2 Flavin 2 Prednisolone 2 Silica 2 IL-1ra 2 Lovastatin 2 K-252a 2 Gentian violet 2 TMS 2 Adriamycin 2 ADM 2 balanced salt solution 2 CET 2 Isoniazid 2 Ramipril 2 citric acid 2 Ketotifen 1 Fulvestrant 1 SMP 1 Galactose 1 MDS 1 AZT 1 Donepezil 1 lactose 1 Vitamin B 1 Irinotecan 1 RFP 1 HCH 1 PFA 1 Crystal Violet 1 Rosuvastatin calcium 1 Iohexol 1 Itraconazole 1 Trimethoprim-sulfamethoxazole 1 Diphenhydramine 1 Escitalopram 1 Lipitor 1 TTC 1 Portal 1 Ibandronate 1 Podophyllum 1 Chloramine T 1 Navelbine 1 R-gene 1 Anakinra 1 Cilomilast 1 NVP 1 more...

Enzyme NADPH oxidase 10295 NADPH oxidase 10176 superoxide dismutase 980 mitogen-activated protein kinase 948 protein kinase C 680 catalase 658 peroxidase 500 xanthine oxidase 359 protein kinase 303 NO synthase 262 ERK 258 renin 202 caspase-3 192 glutathione peroxidase 178 NADPH-diaphorase 144 phospholipase A2 113 ATPase 111 MEK 107 NOS 100 phospholipase C 100 complex I 96 glutathione reductase 92 phosphatidylinositol 3-kinase 82 phospholipase D 79 diaphorase 72 lactate dehydrogenase 71 ascorbate peroxidase 67 focal adhesion kinase 66 AMP-activated protein kinase 66 glucose-6-phosphate dehydrogenase 61 heme oxygenase 56 CPR 54 ACE 54 caspase-1 52 luciferase 49 thrombin 47 lipoxygenase 46 PARP 46 elastase 41 tyrosine hydroxylase 39 calcineurin 39 phosphoinositide 3-kinase 37 AMPK 37 neutrophil elastase 37 phosphodiesterase 35 NQO1 35 MAP 33 succinate dehydrogenase 33 peroxiredoxin 33 glutathione S-transferase 32 AMPK 31 DCF 30 proteasome 30 IKK 29 thioredoxin reductase 27 reverse transcriptase 26 NADH dehydrogenase 26 alkaline phosphatase 25 caspase-9 25 guanylate cyclase 24 alanine aminotransferase 24 trypsin 23 arginase 23 lysozyme 22 adenylate cyclase 22 collagenase 22 xanthine dehydrogenase 22 diaphorase 20 aspartate aminotransferase 19 caspase-8 18 glucose oxidase 18 6-phosphogluconate dehydrogenase 17 6-phosphogluconate dehydrogenase 17 thyroid peroxidase 16 nitrate reductase 16 nitrate reductase 16 nitrate reductase 16 nitrate reductase 16 CaMKII 16 nitrate reductase 16 nitrate reductase 16 demethylase 16 acid phosphatase 16 creatine kinase 15 12-lipoxygenase 15 polyamine oxidase 15 cytochrome oxidase 14 RNA polymerase 14 glutamine synthetase 14 alcohol dehydrogenase 14 glucose-6-phosphatase 13 myosin light chain kinase 13 15-lipoxygenase 13 PKG 12 MMP 12 transcriptase 12 beta-glucuronidase 12 ATP synthase 11 aldose reductase 11 glyceraldehyde-3-phosphate dehydrogenase 11 monoamine oxidase 11 apyrase 10 GSK 10 triphosphatase 10 phosphoenolpyruvate carboxykinase 10 aconitase 10 isocitrate dehydrogenase 10 MIP 10 phosphoenolpyruvate carboxykinase 9 MEKK1 9 DNase 9 cathepsin G 9 3-hydroxy-3-methylglutaryl coenzyme A reductase 9 APC 9 phosphoenolpyruvate carboxykinase 9 transhydrogenase 9 aldehyde dehydrogenase 9 glyceraldehyde-3-phosphate dehydrogenase 9 hexokinase 8 TACE 8 glutamate dehydrogenase 8 glutamate dehydrogenase 8 PDK1 8 glutamate dehydrogenase 8 hexosaminidase 8 isocitrate dehydrogenase 8 neutral sphingomyelinase 8 glycolate oxidase 8 matrix metalloproteinase 9 8 cathepsin B 8 gamma-glutamylcysteine synthetase 8 protein phosphatase 2A 8 adrenodoxin reductase 8 aldehyde dehydrogenase 8 MPP 8 ACS 8 dihydrofolate reductase 8 aldehyde dehydrogenase 7 angiotensin-converting enzyme 2 7 diamine oxidase 7 paraoxonase 7 diacylglycerol kinase 7 paraoxonase 7 tyrosinase 7 pyruvate kinase 7 disulfide reductase 7 AST 7 PAL 7 aldehyde dehydrogenase 7 aldehyde dehydrogenase 7 farnesyltransferase 6 tissue plasminogen activator 6 dehydroascorbate reductase 6 GTP cyclohydrolase I 6 gamma-glutamyl transpeptidase 6 peptidylarginine deiminase 6 citrate synthase 6 5'-nucleotidase 6 PTPase 6 glutathione synthetase 6 more...

Compound oxygen 5074 NADPH 1189 NADPH 1187 nitric oxide 859 hydrogen 800 calcium 726 Dec 716 phosphate 632 acetate 616 H2O2 567 glucose 551 DNA 541 nicotinamide 532 Clin 331 sodium 328 TNF 322 cysteine 316 superoxide radical 306 water 294 Phe 280 tyrosine 263 Ang II 253 NADH 240 ATP 240 nitrogen 235 GSH 230 GSH 230 N-acetylcysteine 224 arginine 218 PMA 214 DPI 214 PMA 211 salt 192 GTP 191 Apocynin 180 Angiotensin II 160 iron 155 NADP 146 leucine 139 NAD 125 ethanol 124 sulfate 122 serine 118 FAD 117 NAD 116 diacetate 113 methionine 110 cAMP 110 glutamate 101 aldosterone 99 zinc 90 potassium 87 THP 85 THP 83 Cardiol 79 nitrate 74 cGMP 74 galactose 72 GDP 71 Panam 67 PEG 67 CO2 66 AMP 65 threonine 63 Tempol 61 creatinine 61 ADP 60 cyanide 58 SDS 58 copper 57 ADP 56 ADP 56 GSSG 55 MDA 55 salicylic acid 55 chromate 54 8-OHdG 53 lysine 51 manganese 49 urea 48 cadmium 47 MEK 47 homocysteine 47 iodine 45 ACh 45 pentose 44 pentose 44 pentose 44 pentose 44 alanine 43 Insulin 43 His 41 PGE 40 STZ 38 FMLP 38 fMet 37 biphenylene 36 pyridine 36 biphenylene 36 hexose 35 MTT 35 hexose 35 hexose 35 proline 35 hexose 35 PEG 34 retinoic acid 34 NMDA 34 Resveratrol 33 H2S 33 MAP 33 ammonium 32 Neuronal 31 aldehyde 31 Mg2+ 31 DMSO 30 NH2 30 bromide 29 Heme 28 FMN 28 CAT 27 glycerol 27 pyrrolidine 27 Triton X-100 27 5-HT 26 Gly 25 prostacyclin 25 CAT 25 Phorbol 25 ammonia 25 CAT 25 EDTA 24 EDTA 24 2-nonenal 24 selenium 23 Tiron 23 NBT 23 benzoic acid 23 pyrrolidine 23 palmitic acid 23 tryptophan 23 PGE2 22 palmitic acid 21 Ascorbic acid 21 PLA 21 Losartan 20 MPTP 20 Asp 19 Arsenic 19 vitamin D 19 mercury 19 aldehyde 18 cobalt 18 ASA 18 Arachidonic acid 18 NO3 18 COS 17 tryptophan 17 Melatonin 17 tryptophan 17 more...

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