Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.6.99.5 (NADH dehydrogenase)
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Human Gene/Protein
EF-hand domain-containing protein 1 13.9
outer dense fiber protein 2 13.9
NADH dehydrogenase 13.9
actin-related protein T2 13.9
NDUFV2 protein 13.9
Matrilin 3 12.9
NADH dehydrogenase III 12.9
C1QL4 12.9
CECR2B 12.9
GTP-binding protein SAR1 12.9
Ribosomal protein S18 12.9
mitochondrial malate dehydrogenase 2, NAD 12.9
G8 protein 12.9
dehydrogenase/reductase member 3 12.9
iron-sulfur protein 3 12.7
40S ribosomal protein S23 12.3
tripartite motif-containing 14 12.3
ATP synthase D chain, mitochondrial 12.3
Ribosomal protein L15 12.3
MTND4 12.0
SLC25A14 11.9
ATP synthase gamma chain 11.9
mitochondrial ribosomal protein L12 11.9
Ras-related protein Rab-2A 11.9
NADH-ubiquinone oxidoreductase chain 1 11.9
SDHA protein 11.9
pyruvate dehydrogenase (lipoamide) beta 11.9
troponin C2 11.9
MURF2 11.7
complex I) 11.5
cytochrome c oxidase subunit 3 11.4
MTND3 11.3
hemoglobin alpha 2 11.3
karyopherin beta 1 11.3
Glutathione S-transferase kappa 1 11.3
RAD23 homolog B 11.3
MT-ND2 11.2
Fas-activated serine/threonine kinase 11.2
LEP503 11.1
CaM-KIIN 11.1
more...
Disease
Brisket disease 12.3
nanophyetiasis 11.1
Chromophobe cell renal carcinoma 10.7
SCA28 9.6
Complex I deficiency 8.9
SPG20 8.4
Diabetic encephalopathy 8.2
Leber's hereditary optic neuropathy 7.9
pediatric disorder 7.7
SPG7 7.5
Echinococcus granulosus infection 7.4
NDI 7.4
White Spot 7.4
mitochondrial myopathy 7.3
Leigh syndrome 7.3
coenurosis 7.3
mitochondrial encephalomyopathy 7.2
marijuana abuse 7.1
Cogan 7.1
Barth syndrome 6.9
Optic neuropathy 6.6
Kearns-Sayre syndrome 6.5
mitochondrial disease 6.2
Diaz 6.2
MERRF 6.2
Dicrocoelium dendriticum 6.1
MELAS 6.0
MELAS 5.7
riboflavin deficiency 5.7
PPR 5.7
testicular dysfunction 5.6
Schistosoma japonicum 5.6
DIA 5.6
chondrolysis 5.5
PCC 5.4
Crouzon syndrome 5.4
optic atrophy 5.3
dyschondroplasia 5.3
Benson 5.2
FDH 5.2
more...
Symptom
Respiration stimulated 12.9
ophthalmoplegia 4.5
hyperoxia 3.8
eds 3.8
dysarthria 3.6
hypotonia 3.3
cerebellar ataxia 3.0
starvation 3.0
chorea 2.8
myoclonus 2.8
pallor 2.6
dystonia 2.4
lethargy 2.4
exertional dyspnea 2.1
exhaustion 1.7
weakness 1.7
paresis 1.4
hypercapnia 0.9
ataxia 0.9
fatigue 0.8
collapse 0.1
acidity -0.0
tremor -0.3
anesthesia -1.3
diarrhea -1.9
seizures -2.4
Drug
Nanaomycin D 12.3
Duroquinone 10.3
Tuareg 9.2
URF 8.9
NADH 8.7
Secobarbital 8.6
Demerol 8.4
Demerol 7.8
FAD 7.4
Sodium thiosulfate 7.3
Flavin 7.0
Vanilla 6.7
Abamectin 6.7
Isoniazid 6.3
AGG 6.2
Novantrone 6.2
Cibacron Blue 6.0
Photofrin II 5.8
Geranium 5.8
Dexon 5.5
SMP 5.3
Bosentan 5.1
Bosentan 5.1
Emodin 5.0
Fructose 5.0
EHDP 4.9
Clofibrate 4.7
Emodin 4.7
NaI 4.6
NaI 4.6
NaI 4.6
NaI 4.6
Adriamycin 4.5
Glycerol 4.3
Riboflavin 4.3
Ranitidine 4.2
citric acid 4.2
Xanthium 4.2
ROS 4.1
Photofrin 4.0
more...
Enzyme
NADH dehydrogenase 13.9
diaphorase 12.3
EC 3.2.1.70 12.3
complex I 11.8
EC 1.1.99.16 10.9
4-N-trimethylaminobutyraldehyde dehydrogenase 10.7
malate oxidase 10.6
mannitol-1-phosphatase 10.2
glutaconyl-CoA decarboxylase 9.9
DHOdehase 9.5
6-phosphogluconate dehydratase 9.5
KGOR 9.4
ADP-dependent glucokinase 9.2
thiosulfate dehydrogenase 9.1
NQO2 9.1
methylmalonyl-CoA epimerase 8.9
ubiquinol-cytochrome c oxidoreductase 8.8
succinate dehydrogenase 8.7
transhydrogenase 8.6
mannitol 1-phosphate dehydrogenase 8.5
EC 1.1.1.39 8.5
thiosulfate dehydrogenase 8.4
bidirectional hydrogenase 8.3
dihydrodipicolinate reductase 8.3
heterodisulfide reductase 8.3
fumarate reductase 8.3
proline dehydrogenase 8.2
phospho-beta-glucosidase 8.2
3-hydroxybutyryl-CoA dehydrogenase 8.1
lactate oxidase 8.1
succinic dehydrogenase 8.1
alpha-ketoglutarate dehydrogenase 8.1
pyruvate:ferredoxin oxidoreductase 8.0
membrane-bound hydrogenase 7.9
Delta6-desaturase 7.9
D-dopachrome tautomerase 7.8
deoxyhypusine hydroxylase 7.8
phosphoenolpyruvate synthase 7.8
glycerol 3-phosphate dehydrogenase 7.8
cytochrome oxidase 7.8
more...
Compound
Adriamycin aglycone 13.9
Rifamycin S 11.9
Syrosingopine 11.9
Xanthomegnin 11.5
Succinic acid monomethyl ester 11.3
Fenpyroximate 10.9
CoQ6 10.8
2-bromobenzoic acid 10.7
D-Carnitine 10.7
1,2,3-benzothiadiazole 10.5
Quinalizarin 10.4
5-Methoxyindole 10.3
Coproporphyrin III 10.2
3-succinoylpyridine 10.1
2,2',5,5'-TCB 10.0
Coproporphyrin III 9.9
Duroquinone 9.8
2,2,4-trimethyl-1,2-dihydroquinoline 9.7
Methacrylonitrile 9.7
D-Proline 9.5
Spartin 9.3
Sedoheptulose 9.2
Glyceollin 9.2
Glyceollin 9.2
1-Methyl-4-phenylpyridinium 9.0
ubiquinone 8.9
Janus Green B 8.9
NADH 8.7
Protopine 8.7
Adrenochrome 8.6
Ferricyanide 8.6
6-hydroxynicotinic acid 8.4
dimethyl succinate 8.4
6-hydroxynicotinic acid 8.4
FMN 8.2
Amytal 8.2
Enterobactin 8.1
2,6-dichlorophenol 8.1
Rotenone 8.1
protoporphyrinogen IX 8.0
more...