Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.6.99.3 (
diaphorase
)
5,903
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
NADH dehydrogenase
2018
diaphorase
1890
NADH
1753
NADPH
1074
nitric oxide synthase
588
reductase
511
cytochrome c
448
NAD
419
Sep
413
microsomal
413
cytochrome
403
cytochrome c oxidase
382
ATP
368
Mol
349
ubiquinone
299
cytochrome b
277
oxidoreductase
276
cytochrome P-450
240
ATPase
232
FAD
202
NADH diaphorase
192
endoplasmic reticulum
189
flavoprotein
163
superoxide dismutase
163
polypeptide
158
lactate dehydrogenase
151
catalase
144
NADP
142
malate dehydrogenase
138
membrane-bound
133
ferredoxin
132
FMN
131
complex I)
126
neuronal nitric oxide synthase
124
cytochrome b5
123
NAD+
121
ADP
120
acetylcholinesterase
109
ATP synthase
105
cytochrome P450
99
GSH
87
alkaline phosphatase
86
acid phosphatase
80
SDS
80
tRNA
77
DT-diaphorase
77
citrate synthase
74
glucose-6-phosphate dehydrogenase
70
NADP+
70
EPR
69
glucose-6-phosphatase
68
5'-nucleotidase
67
peroxidase
66
ND1
65
glutathione reductase
64
P450
60
Gen
58
glutathione peroxidase
57
tyrosine hydroxylase
56
cytochrome bc1
56
glutamate dehydrogenase
56
isocitrate dehydrogenase
54
esterase
54
xanthine oxidase
53
substance P
52
NADPH-cytochrome P-450 reductase
51
membrane protein
50
calmodulin
50
lipoamide dehydrogenase
49
glutathione S-transferase
49
olfactory
49
insulin
48
Cytochrome c
48
choline acetyltransferase
46
cytochrome aa3
45
B13
45
alcohol dehydrogenase
44
ND4
44
ND5
43
NADH-ubiquinone reductase
42
more...
Disease
cancer
148
GSH
87
SDS
80
tumor
80
ischemia
72
Parkinson's disease
55
diabetes
47
Mycobacterium
39
NAME
37
depression
36
hepatocellular carcinoma
34
cold
33
tuberculosis
33
carcinogenesis
32
Alzheimer's disease
30
pheochromocytoma
27
mitochondrial myopathy
26
carcinoma
25
PCC
24
Leigh syndrome
22
lactic acidosis
21
schizophrenia
19
varices
19
breast cancer
18
heart failure
17
Huntington's disease
17
myopathy
17
Echinococcus
17
hypertension
17
melanoma
17
Leber's hereditary optic neuropathy
15
mole
15
mole
15
encephalopathy
15
neuroblastoma
14
cardiomyopathy
14
stroke
13
cholera
13
atherosclerosis
13
worms
11
type 2 diabetes
11
mitochondrial encephalomyopathy
11
adenocarcinoma
11
parkinsonism
11
neuropathy
11
obesity
11
mitochondrial disease
10
uterus
10
myocardial ischemia
10
SEM
10
dehydration
10
malaria
10
tumor growth
10
lymphoma
10
leukemia
10
Chagas
9
colorectal cancer
9
tumorigenesis
9
methemoglobinemia
9
epilepsy
9
epididymis
8
cerebral ischemia
8
MCF
8
chronic granulomatous disease
8
iron deficiency
8
Schistosoma japonicum
8
cholestasis
7
fits
7
lung cancer
7
DIA
7
dementia
7
colon cancer
7
Steroids
7
Duchenne muscular dystrophy
7
enzyme deficiency
7
myocardial infarction
7
vagina
7
Mycoplasma
6
Lissauer
6
liver disease
6
more...
Symptom
pain
19
anesthesia
18
starvation
16
weakness
16
seizures
15
fatigue
14
hyperoxia
11
hypotonia
11
collapse
10
ophthalmoplegia
10
functional recovery
6
ataxia
5
dystonia
5
respiratory distress
4
exhaustion
4
cyanosis
3
tremor
3
lethargy
3
analgesia
3
hepatomegaly
3
cerebellar ataxia
3
hypothermia
3
dysarthria
3
myoclonus
2
anorexia
2
eds
2
constipation
2
ketonuria
2
Decreased activity
2
vomiting
2
pallor
2
incoordination
2
acidity
2
paresis
2
headache
2
memory loss
1
tonic-clonic seizure
1
Respiration stimulated
1
twitching
1
hypertonia
1
flushing
1
hemiplegia
1
muscle rigidity
1
spasticity
1
nasal congestion
1
exertional dyspnea
1
chorea
1
nausea
1
HSA
1
ACHE
1
agitation
1
paraparesis
1
urinary frequency
1
hemoptysis
1
hypercapnia
1
muscle stiffness
1
chronic constipation
1
anosmia
1
stigma
1
abnormal gait
1
diarrhea
1
tachypnea
1
clubbing
1
drooling
1
arthralgia
1
acute stress
1
sleepiness
1
thinning
1
myalgia
1
orofacial pain
1
dyspnea
1
Drug
NADH
1791
FAD
202
ascorbate
80
ROS
37
lysine
35
Gel
22
vitamin E
18
Ethanol
17
citric acid
17
Glutathione
14
Asn
11
NBT
9
caffeine
9
Vitamin K
9
Adriamycin
8
Nitric Oxide
8
Cardiovasc
8
DNase I
6
Dermatol
6
lactose
6
Vitamin E
6
Flavin
6
Cibacron Blue
5
Isoniazid
5
AZT
5
Clofibrate
5
AZT
5
Captopril
4
AGG
4
Fraction
4
Nephron
4
CaCl2
4
Leaf
4
Fructose
4
CaCl2
4
CaCl2
4
CSF
3
CPR
3
Parkin
3
Trifluoperazine
3
PCP
3
Indomethacin
3
URF
3
Idebenone
3
Glycerol
3
Parkin
3
PCB
3
Palmitoyl
3
pyridoxal phosphate
3
Heme
3
L-tyrosine
3
Glucagon
2
Ranitidine
2
Chlorate
2
p75
2
CTX
2
Naftidrofuryl
2
Methylene blue
2
Amiloride
2
Ginseng
2
Kainic acid
2
niacin
2
ICI
2
Capsicum
2
Apomorphine
2
Aminoguanidine
2
DFP
2
Monensin
2
MAP
2
Photofrin
2
PTH
2
Bifidobacterium
2
SMP
2
Tacrolimus
2
Sodium nitroprusside
2
ADR
2
ADM
2
Amiloride
2
Photofrin II
2
Monit
2
more...
Enzyme
diaphorase
5903
complex I
2164
NADH dehydrogenase
2026
NQO1
1952
NADPH-diaphorase
1920
diaphorase
1905
CPR
1904
succinate dehydrogenase
434
cytochrome oxidase
340
ATPase
289
NO synthase
267
superoxide dismutase
185
lactate dehydrogenase
182
malate dehydrogenase
154
catalase
151
demethylase
133
ATP synthase
119
acetylcholinesterase
111
peroxidase
93
succinic dehydrogenase
92
glucose-6-phosphate dehydrogenase
89
alkaline phosphatase
87
acid phosphatase
81
NOS
80
citrate synthase
80
nitrate reductase
76
NADPH oxidase
72
nitrate reductase
71
nitrate reductase
70
nitrate reductase
69
nitrate reductase
68
nitrate reductase
68
glucose-6-phosphatase
68
5'-nucleotidase
67
glutathione S-transferase
66
glutathione reductase
63
glutathione peroxidase
61
NADPH oxidase
61
isocitrate dehydrogenase
60
glycerol-3-phosphate dehydrogenase
56
monoamine oxidase
55
pyruvate dehydrogenase
55
isocitrate dehydrogenase
55
glutamate dehydrogenase
55
glutamate dehydrogenase
54
glycerol-3-phosphate dehydrogenase
54
glutamate dehydrogenase
54
hydrogenase
53
hydrogenase
53
alcohol dehydrogenase
52
tyrosine hydroxylase
51
NADH-cytochrome b5 reductase
50
xanthine oxidase
50
aryl hydrocarbon hydroxylase
48
adrenodoxin reductase
47
choline acetyltransferase
46
trypsin
45
hexokinase
40
transhydrogenase
38
pyruvate kinase
36
pyruvate dehydrogenase
33
pyruvate dehydrogenase
33
alpha-ketoglutarate dehydrogenase
29
aspartate aminotransferase
25
ubiquinol-cytochrome c oxidoreductase
25
gamma-glutamyl transpeptidase
25
RNA polymerase
24
aconitase
23
fumarate reductase
21
6-phosphogluconate dehydrogenase
21
UDP-glucuronosyltransferase
21
fumarase
21
6-phosphogluconate dehydrogenase
21
protein kinase
20
alanine aminotransferase
20
nitrite reductase
20
nitrite reductase
20
creatine kinase
20
phosphofructokinase
20
nitrite reductase
20
more...
Compound
NADH
1787
NADPH
1084
NADPH
1078
phosphate
964
nicotinamide
930
oxygen
620
nitric oxide
561
DNA
555
NAD
534
Dec
436
NAD
419
ATP
369
iron
324
ubiquinone
307
ubiquinol
300
NADP
285
sodium
270
glucose
226
FAD
204
arginine
175
hydrogen
175
calcium
163
water
158
cyanide
142
FMN
132
sulfate
130
glutamate
125
ADP
125
ADP
121
ADP
120
ethanol
116
H2O2
104
GSH
97
GSH
97
SDS
95
ammonium
93
Triton X-100
93
Clin
90
aniline
90
acetate
83
nitrate
82
nitrogen
77
glycerol
75
pyrene
71
salt
68
methionine
67
leucine
67
CO2
67
pyridine
63
alanine
62
cysteine
59
potassium
56
copper
55
succinic acid
53
galactose
52
His
51
Cytochrome c
48
lysine
46
2-oxoglutarate
46
alcohol dehydrogenase
46
tyrosine
40
superoxide radical
39
AMP
39
DEAE
37
CoQ
36
naphthoquinone
36
naphthoquinone
36
naphthoquinone
36
naphthoquinone
36
naphthoquinone
36
naphthoquinone
36
naphthoquinone
36
EDTA
34
EDTA
34
CoA
31
Mg2+
31
Rotenone
29
urea
29
zinc
29
tryptophan
27
more...