Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.6.99.3 (diaphorase)
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Human Gene/Protein
EF-hand domain-containing protein 1 12.4
NDUFV2 protein 12.4
hemoglobin gamma-G 12.4
diaphorase 12.4
TRM112-like protein 12.4
outer dense fiber protein 2 12.4
actin-related protein T2 12.4
NADH dehydrogenase 12.4
CGI-49 12.4
NADH diaphorase 12.3
G8 protein 11.4
dehydrogenase/reductase member 3 11.4
CECR2B 11.4
NADH dehydrogenase III 11.4
C1QL4 11.4
GTP-binding protein SAR1 11.4
mitochondrial malate dehydrogenase 2, NAD 11.4
Matrilin 3 11.4
Ribosomal protein S18 11.4
iron-sulfur protein 3 11.3
Diaphorase 11.0
CD81 antigen 10.8
Ribosomal protein L15 10.8
40S ribosomal protein S23 10.8
outer dense fiber of sperm tails 2 10.8
ferritin, light polypeptide 10.8
ATP synthase D chain, mitochondrial 10.8
ubiquinone-binding protein 10.8
UQCR 10.8
tripartite motif-containing 14 10.8
MTND4 10.5
SLC25A14 10.4
pyruvate carboxylase, mitochondrial 10.4
NADH-ubiquinone oxidoreductase chain 1 10.4
Ras-related protein Rab-2A 10.4
pyruvate dehydrogenase (lipoamide) beta 10.4
ATP synthase gamma chain 10.4
SDHA protein 10.4
troponin C2 10.4
TM7SF3 10.4
more...
Disease
Brisket disease 10.8
nanophyetiasis 9.6
Chromophobe cell renal carcinoma 9.2
SCA28 8.1
vitamin B deficiency 7.9
Pyridoxine deficiency 7.6
DTD 7.3
Chloracne 7.3
Lissauer 7.3
Bordetella infection 7.3
PPPP 7.2
Persistent pulmonary hypertension 7.0
mitochondrial myopathy 7.0
SPG20 7.0
DIA 6.9
Reflux nephropathy 6.9
EBSS 6.8
mitochondrial encephalomyopathy 6.8
Diabetic encephalopathy 6.7
RCA1 6.5
Complex I deficiency 6.5
Leber's hereditary optic neuropathy 6.4
Leigh syndrome 6.3
FCU 6.2
pediatric disorder 6.2
CGD 6.2
Ileum 6.2
disorders of amino acid metabolism 6.1
erythrasma 6.1
SPG7 6.1
stage I breast cancer 6.0
Echinococcus granulosus infection 6.0
NDI 6.0
White Spot 6.0
coenurosis 5.8
cardiosclerosis 5.8
Microangiopathy 5.8
CBS deficiency 5.7
marijuana abuse 5.7
Klebs 5.6
more...
Symptom
Respiration stimulated 11.4
ACHE 4.5
Decreased activity 4.3
ketonuria 4.3
ophthalmoplegia 4.0
hyperoxia 3.5
eds 3.3
hypotonia 3.3
drooling 3.0
incoordination 2.6
clubbing 2.6
orofacial pain 2.5
muscle rigidity 2.3
urinary frequency 2.3
abnormal gait 2.3
nasal congestion 2.2
cerebellar ataxia 2.2
muscle stiffness 2.1
hypertonia 2.1
cyanosis 2.1
dysarthria 2.1
pallor 2.1
chronic constipation 2.1
tonic-clonic seizure 2.0
anosmia 1.8
starvation 1.8
dystonia 1.7
lethargy 1.5
hepatomegaly 1.5
twitching 1.4
chorea 1.4
myoclonus 1.3
functional recovery 1.3
weakness 1.2
tachypnea 1.1
paraparesis 1.0
collapse 0.9
paresis 0.9
HSA 0.8
ataxia 0.8
more...
Drug
Juvela 11.4
Nanaomycin D 10.8
Cocarboxylase 9.6
Duroquinone 8.8
NADH 8.8
Tuareg 7.8
FAD 7.6
URF 7.5
Diethylpropion 7.4
Pegaspargase 7.2
Naftidrofuryl 7.1
Secobarbital 7.1
Idebenone 7.1
Demerol 7.0
Flavin 6.6
Atabrine 6.5
Demerol 6.4
Dodecyl Sulfate 6.2
Chlorate 6.2
Cicletanine 6.0
Cibacron Blue 5.8
Sodium thiosulfate 5.8
Palmitoyl 5.8
Malonaldehyde 5.8
Doxapram 5.8
Clofibrate 5.6
Photofrin II 5.4
Vanilla 5.3
NBT 5.2
Trifluoperazine 5.2
Abamectin 5.2
Vitamin K 5.1
Fenbendazole 5.1
Atovaquone 5.0
Vardenafil 5.0
SMP 4.8
Isoniazid 4.8
AGG 4.8
Novantrone 4.8
Aminoguanidine 4.7
more...
Enzyme
diaphorase 12.4
malate-lactate transhydrogenase 12.4
4NQO reductase 12.4
NADH dehydrogenase 12.3
diaphorase 11.9
asparagusate dehydrogenase 11.4
NADPH-diaphorase 11.4
CPR 10.9
EC 3.2.1.70 10.8
NQO1 10.7
EC 1.1.1.108 10.4
complex I 10.4
aquacobalamin reductase 10.2
12alpha-hydroxysteroid dehydrogenase 10.1
methylviologen-reducing hydrogenase 10.1
malate oxidase 9.7
ubiquinol-cytochrome c oxidoreductase 9.6
D-sorbitol dehydrogenase 9.5
EC 1.1.99.16 9.4
4-N-trimethylaminobutyraldehyde dehydrogenase 9.2
bidirectional hydrogenase 9.1
ferric leghemoglobin reductase 9.1
DHOdehase 9.0
NADH-cytochrome b5 reductase 9.0
NAD+ synthetase 8.9
benzoate dioxygenase 8.8
4-hydroxyproline 2-epimerase 8.8
adrenodoxin reductase 8.7
3beta-HSDH 8.6
CMP-sialic acid:lactosylceramide sialyltransferase 8.4
glutaconyl-CoA decarboxylase 8.4
4-hydroxybutyrate dehydrogenase 8.4
p-hydroxyphenylacetate 3-hydroxylase 8.3
sucrose-phosphatase 8.2
transhydrogenase 8.2
succinate dehydrogenase 8.2
succinic dehydrogenase 8.2
nicotinic acid hydroxylase 8.1
beta-hydroxybutyrate dehydrogenase 8.1
glutathione oxidase 8.1
more...
Compound
S-Methylisothiourea sulfate 12.4
Optochin hydrochloride 12.4
Adriamycin aglycone 12.4
Ubisemiquinone 11.4
Asparagusate 11.4
Bis(p-bromophenyl) ether 11.4
1-bromoheptane 11.0
Hyponitrite 10.8
Syrosingopine 10.4
undecylbenzene 10.4
Rifamycin S 10.4
CB 1954 10.3
spirost-5-en-3-ol 10.1
Xanthomegnin 10.1
Funiculosin 10.1
ubiquinol 9.9
Trichloropropene oxide 9.8
Succinic acid monomethyl ester 9.8
Tirandamycin 9.8
Stigmatellin 9.8
Diphenyliodonium chloride 9.6
TNBT 9.5
Nitromin 9.4
CoQ6 9.3
D-Carnitine 9.2
Sinulariolide 9.2
1,2,3-benzothiadiazole 9.1
Quinalizarin 8.9
2-hydroxynaphthoquinone 8.8
5-Methoxyindole 8.8
NADH 8.8
Pyrrolnitrin 8.8
2-hydroxynaphthoquinone 8.7
Coproporphyrin III 8.7
Cytochrome c1 8.6
3-succinoylpyridine 8.6
2,2',5,5'-TCB 8.5
dihydrolipoamide 8.4
Ferricyanide 8.4
Coproporphyrin III 8.4
more...