Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.6.5.3 (complex I)
 8,901 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
NADH dehydrogenase 2018
NADH 1618
ATP 1154
Mol 866
ubiquinone 690
Sep 592
complex I) 498
NAD 450
cytochrome c 372
cytochrome c oxidase 360
oxidoreductase 309
NADH-ubiquinone oxidoreductase 292
cytochrome 282
reductase 281
ADP 274
ROS 251
superoxide dismutase 234
ATP synthase 228
B13 210
NADPH 203
more...
Disease
Parkinson's disease 817
cancer 395
ischemia 240
tumor 234
Leigh syndrome 205
GSH 178
mitochondrial disease 176
Leber's hereditary optic neuropathy 161
lactic acidosis 161
diabetes 156
Alzheimer's disease 142
neuroblastoma 122
parkinsonism 112
stroke 108
cardiomyopathy 93
encephalopathy 90
type 2 diabetes 86
myopathy 82
SDS 81
mitochondrial myopathy 75
more...
Symptom
weakness 67
seizures 65
hypotonia 62
collapse 47
ataxia 44
dystonia 39
starvation 36
ophthalmoplegia 30
fatigue 25
hyperoxia 23
anesthesia 18
tremor 15
vomiting 13
hypothermia 12
spasticity 11
cerebellar ataxia 11
myoclonus 11
functional recovery 10
dysarthria 8
diarrhea 8
more...
Drug
NADH 1617
ROS 251
FAD 97
ascorbate 88
vitamin E 44
Parkin 42
lysine 42
Parkin 42
citric acid 33
THF 23
Gel 20
Cardiovasc 19
Glutathione 18
CSF 14
Adriamycin 13
Asn 12
DNase I 11
Indomethacin 11
Ethanol 9
Dermatol 9
more...
Enzyme
complex I 8901
diaphorase 2164
NADH dehydrogenase 2067
succinate dehydrogenase 1057
cytochrome oxidase 696
ATPase 319
superoxide dismutase 302
ATP synthase 243
catalase 215
CPR 176
citrate synthase 166
AMP-activated protein kinase 127
NQO1 122
MPP 122
caspase-3 120
protein kinase 114
lactate dehydrogenase 104
mitogen-activated protein kinase 103
pyruvate dehydrogenase 98
NADPH oxidase 96
more...
Compound
oxygen 2039
NADH 1615
DNA 1341
ATP 1154
ubiquinone 688
Dec 654
NAD 571
iron 541
glucose 472
NAD 450
hydrogen 332
calcium 319
ADP 291
glutamate 286
ADP 277
ADP 275
sodium 229
Rotenone 224
NADPH 203
NADPH 203
more...