Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.6.5.3 (
complex I
)
8,901
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Total synthesis of pyranicin was achieved using
Cl2Pd
(CH3CN)2-catalyzed diastereoselective cyclization of the allylic ester as the key step. The inhibitory activity of this compound for mitochondrial
NADH-ubiquinone oxidoreductase
(complex I) was slightly poorer than that of ordinary mono-THF acetogenins such as cis-solamin.
...
PMID:Synthesis of pyranicin and its inhibitory action with bovine heart mitochondrial complex I. 1825 47
