Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.6.5.3 (
complex I
)
8,901
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A 33-month-old boy with recurrent stroke-like episodes had angiographic features characteristic of
moyamoya
syndrome. Mitochondrial encephalomyopathy was suspected because of lactic acidosis and ptosis. Studies of oxidative metabolism on isolated skeletal muscle mitochondria revealed impairment of
NADH-coenzyme Q reductase
activity. Mitochondrial metabolic disorders may cause
moyamoya
syndrome when other known associated factors are absent.
...
PMID:Impaired NADH-CoQ reductase activity in a child with moyamoya syndrome. 314 83
