Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.6.5.2 (
NQO1
)
6,196
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
NQO1
2261
diaphorase
1890
DT-diaphorase
1511
NAD
1039
quinone reductase
951
NADPH
861
NADH
771
Nrf2
639
nitric oxide synthase
565
heme oxygenase-1
439
quinone oxidoreductase
436
Sep
416
GSH
408
superoxide dismutase
376
glutathione S-transferase
375
catalase
368
reductase
367
Mol
361
HO-1
333
erythroid
316
oxidoreductase
307
glutathione peroxidase
239
cytochrome P450
189
glutathione reductase
183
microsomal
177
xenobiotic
176
CYP1A1
175
p53
159
NADP
158
ROS
148
FAD
146
SOD
140
lactate dehydrogenase
129
flavoprotein
126
TNF
126
GCLC
122
GSTM1
121
cytochrome
119
ATP
116
neuronal nitric oxide synthase
114
ferredoxin
114
cytochrome c
111
inducible nitric oxide synthase
108
caspase-3
105
GSTP1
101
GSTT1
101
GST
99
P450
87
acetylcholinesterase
86
GCLM
84
myeloperoxidase
84
antioxidant enzyme
82
IL-6
82
CAT
77
polypeptide
76
glutamate-cysteine ligase
73
NQO1 protein
73
peroxidase
72
aryl hydrocarbon receptor
71
glucose-6-phosphate dehydrogenase
71
cytochrome P-450
70
endoplasmic reticulum
70
CYP1B1
70
xanthine oxidase
70
ubiquinone
69
NRF2
69
CPR
69
CYP2E1
69
tumor necrosis factor
69
tyrosine hydroxylase
69
alkaline phosphatase
68
NF-E2-related factor 2
68
CYP1A2
66
lipopolysaccharide
65
FMN
65
glutathione transferase
64
NAD+
63
Bcl-2
63
NADP+
62
NMR
61
more...
Disease
cancer
905
tumor
408
GSH
408
carcinogenesis
295
hepatocellular carcinoma
214
breast cancer
126
lung cancer
85
adenocarcinoma
76
Parkinson's disease
76
carcinoma
70
diabetes
68
tumorigenesis
65
MCF
62
leukemia
58
ischemia
58
colon cancer
58
Alzheimer's disease
49
neuroblastoma
42
melanoma
42
colorectal cancer
40
NAME
38
non-small cell lung cancer
37
prostate cancer
35
PCC
35
pheochromocytoma
35
SDS
35
bladder cancer
33
tumor growth
32
squamous cell carcinoma
31
chemical carcinogenesis
28
acute myeloid leukemia
27
obesity
27
lung carcinoma
26
stroke
25
atherosclerosis
23
pancreatic cancer
23
DTD
21
cerebral ischemia
21
lymphoma
20
Huntington's disease
19
varices
18
hypertension
18
depression
18
type 2 diabetes
17
renal disease
17
acute lymphoblastic leukemia
17
asthma
17
AIN
16
liver cancer
16
chronic obstructive pulmonary disease
16
cardiovascular disease
16
hyperglycemia
16
Mycobacterium
16
diabetic nephropathy
15
myelodysplastic syndrome
15
skin cancer
14
bovine leukemia
14
hepatoblastoma
14
tuberculosis
14
childhood ALL
14
schizophrenia
14
colitis
14
liver cancer
13
macular degeneration
13
B-cell lymphoma
13
uterus
12
cognitive impairment
12
brain edema
12
XPD
12
mole
11
multiple sclerosis
11
cold
11
heart failure
11
tumor progression
11
mole
10
malnutrition
10
myocardial ischemia
10
liver fibrosis
10
gastric cancer
10
liver disease
10
more...
Symptom
pain
31
hyperoxia
21
seizures
15
starvation
9
fatigue
9
anesthesia
9
functional recovery
8
diarrhea
6
respiratory distress
4
thinning
4
acidity
4
hepatomegaly
4
weakness
4
collapse
3
hypothermia
3
vomiting
3
dry eye
3
exhaustion
3
ataxia
2
nausea
2
constipation
2
menopausal symptoms
2
anorexia
2
memory loss
2
dyspnea
2
headache
2
analgesia
2
tachypnea
2
pallor
2
Involuntary Movement
2
stigma
1
hot flashes
1
orofacial pain
1
tonic-clonic seizure
1
hypotonia
1
urinary frequency
1
twitching
1
spasticity
1
nasal congestion
1
Mills
1
ACHE
1
agitation
1
eds
1
chronic constipation
1
erythema
1
ophthalmoplegia
1
abdominal pain
1
hemoptysis
1
lethargy
1
Decreased activity
1
ketonuria
1
cyanosis
1
anosmia
1
dry skin
1
abnormal gait
1
masculinization
1
disturbed balance
1
acute stress
1
cachexia
1
sleepiness
1
arthralgia
1
dystonia
1
overweight
1
myalgia
1
fasciculation
1
Drug
NADH
773
ROS
148
FAD
146
ascorbate
55
Vitamin K
44
Glutathione
31
Heme
22
vitamin E
21
lysine
18
Gel
15
Cardiovasc
13
Ethanol
10
caffeine
9
Adriamycin
9
Nitric Oxide
8
NBT
8
IL-2
7
Mutagen
7
Cibacron Blue
7
Arsenic trioxide
7
CTX
6
citric acid
6
Glycyrrhiza
6
MAP
6
PCB
5
Bifidobacterium
5
Flavin
5
Rutin
5
Dermatol
5
GEO
4
Idebenone
4
Monit
4
CPT-11
4
CSF
4
CTX
4
BH4
4
Captopril
4
CTX
4
BZQ
4
Vitamin E
4
IFN-gamma
3
THF
3
EE2
3
Photofrin
3
Estrogens
3
Tannic acid
3
L-tyrosine
3
lactose
3
Leaf
3
Nephron
3
DEX
3
Propofol
3
Itraconazole
3
Fraction
3
MDS
3
CaCl2
2
CaCl2
2
Atabrine
2
Ciprofibrate
2
Simvastatin
2
CaCl2
2
Riboflavin
2
DFP
2
Parkin
2
CPR
2
Apomorphine
2
ADR
2
Salicylate
2
Fidarestat
2
DNase I
2
Sodium nitroprusside
2
Aloe
2
ABC
2
ZnO
2
Fidarestat
2
Parkin
2
niacin
2
EPA
2
Ginseng
2
NVP
2
more...
Enzyme
NQO1
6196
diaphorase
1952
NADPH-diaphorase
1903
diaphorase
1897
glutathione S-transferase
507
superoxide dismutase
490
catalase
429
NO synthase
256
glutathione peroxidase
255
glutathione reductase
191
peroxidase
155
heme oxygenase
152
lactate dehydrogenase
146
mitogen-activated protein kinase
129
complex I
122
CPR
119
luciferase
98
gamma-glutamylcysteine synthetase
95
acetylcholinesterase
87
succinate dehydrogenase
86
glucose-6-phosphate dehydrogenase
86
NQO2
83
ATPase
80
ERK
77
caspase-3
76
UDP-glucuronosyltransferase
73
NOS
72
alkaline phosphatase
69
xanthine oxidase
68
tyrosine hydroxylase
64
alanine aminotransferase
63
aspartate aminotransferase
62
NADH dehydrogenase
58
NADH-cytochrome b5 reductase
51
acid phosphatase
50
cytochrome oxidase
47
soluble epoxide hydrolase
47
choline acetyltransferase
46
adrenodoxin reductase
44
protein kinase
43
succinic dehydrogenase
41
PARP
41
alcohol dehydrogenase
40
aldehyde dehydrogenase
38
proteasome
38
ornithine decarboxylase
38
protein kinase C
36
gamma-glutamyl transpeptidase
36
AMP-activated protein kinase
36
demethylase
36
NADPH oxidase
35
ECH
33
microsomal epoxide hydrolase
33
aryl hydrocarbon hydroxylase
32
AST
31
NADPH oxidase
31
malate dehydrogenase
30
hydrogenase
29
hydrogenase
29
thioredoxin reductase
28
aldehyde dehydrogenase
27
aldehyde dehydrogenase
26
aldehyde dehydrogenase
26
nitrate reductase
26
aldehyde dehydrogenase
26
AMPK
25
AMPK
24
glycerol-3-phosphate dehydrogenase
22
myrosinase
22
glycerol-3-phosphate dehydrogenase
22
nitrate reductase
21
nitrate reductase
21
nitrate reductase
21
nitrate reductase
21
nitrate reductase
21
monoamine oxidase
20
carbonyl reductase
20
tyrosinase
20
topoisomerase
17
ACS
17
more...
Compound
NAD
1102
NAD
1039
nicotinamide
882
NADPH
867
NADPH
865
phosphate
863
oxygen
808
NADH
770
DNA
677
nitric oxide
563
Dec
451
GSH
426
GSH
426
NADP
313
hydrogen
239
water
188
sodium
169
glucose
163
cysteine
150
FAD
147
arginine
140
hydroquinone
139
pyrene
133
TNF
126
iron
123
ATP
116
MDA
107
H2O2
105
naphthoquinone
101
naphthoquinone
101
naphthoquinone
101
naphthoquinone
101
naphthoquinone
101
naphthoquinone
101
naphthoquinone
101
nitrogen
97
Clin
96
ethanol
92
calcium
91
benzene
90
glutamate
82
ubiquinone
79
CAT
77
CAT
77
CAT
77
BHC
76
sulfate
73
UDP
71
acetate
70
pyridine
67
FMN
67
salt
62
N-acetylcysteine
56
CO2
56
GSSG
54
MTT
52
Quinone
52
His
51
anthracene
51
cyanide
47
urea
45
creatinine
45
galactose
40
bromide
37
SDS
37
Sulforaphane
37
nitrate
36
zinc
35
MMC
35
ammonium
35
aldehyde
35
cadmium
35
copper
34
Menadione
34
tyrosine
33
methionine
31
leucine
31
alcohol dehydrogenase
30
selenium
30
serine
29
more...