Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.6.5.2 (NQO1)
 6,196 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
NQO1 2261
diaphorase 1890
DT-diaphorase 1511
NAD 1039
quinone reductase 951
NADPH 861
NADH 771
Nrf2 639
nitric oxide synthase 565
heme oxygenase-1 439
quinone oxidoreductase 436
Sep 416
GSH 408
superoxide dismutase 376
glutathione S-transferase 375
catalase 368
reductase 367
Mol 361
HO-1 333
erythroid 316
oxidoreductase 307
glutathione peroxidase 239
cytochrome P450 189
glutathione reductase 183
microsomal 177
xenobiotic 176
CYP1A1 175
p53 159
NADP 158
ROS 148
FAD 146
SOD 140
lactate dehydrogenase 129
flavoprotein 126
TNF 126
GCLC 122
GSTM1 121
cytochrome 119
ATP 116
ferredoxin 114
neuronal nitric oxide synthase 114
cytochrome c 111
inducible nitric oxide synthase 108
caspase-3 105
GSTT1 101
GSTP1 101
GST 99
P450 87
acetylcholinesterase 86
GCLM 84
myeloperoxidase 84
antioxidant enzyme 82
IL-6 82
CAT 77
polypeptide 76
glutamate-cysteine ligase 73
NQO1 protein 73
peroxidase 72
glucose-6-phosphate dehydrogenase 71
aryl hydrocarbon receptor 71
endoplasmic reticulum 70
cytochrome P-450 70
CYP1B1 70
xanthine oxidase 70
CYP2E1 69
tumor necrosis factor 69
tyrosine hydroxylase 69
ubiquinone 69
NRF2 69
CPR 69
NF-E2-related factor 2 68
alkaline phosphatase 68
CYP1A2 66
FMN 65
lipopolysaccharide 65
glutathione transferase 64
NAD+ 63
Bcl-2 63
NADP+ 62
NMR 61
NQO2 59
Ah receptor 56
ATPase 54
QR1 53
substance P 52
HMOX1 51
NADH dehydrogenase 51
acid phosphatase 50
p38 50
NF-E2 48
olfactory 48
SOD2 47
choline acetyltransferase 46
epoxide hydrolase 46
SOD1 45
GCS 45
COX-2 44
Kelch-like ECH-associated protein 1 44
NADPH-cytochrome P-450 reductase 44
PI3K 43
lipoamide dehydrogenase 42
cytochrome b5 41
neuropeptide Y 41
colon carcinoma 41
JNK 40
somatostatin 40
LPS 40
cytochrome b 40
membrane-bound 40
insulin 39
UDP-glucuronosyltransferase 39
cytokine 38
ornithine decarboxylase 38
p65 38
thymus 38
1A1 38
proteasome 37
ERK 37
LDH 37
Diaphorase 37
albumin 35
SDS 35
MAPK 35
axonal 35
PCC 35
esterase 34
EPHX1 34
IL-8 34
p21 34
parvalbumin 33
gut 33
aspartate aminotransferase 33
calbindin 33
calcitonin 32
microsomal epoxide hydrolase 32
NAT2 31
AST 31
PARP 31
anti-apoptotic protein 29
ubiquitin 29
cytochrome P450 1A1 28
p45 28
aryl hydrocarbon hydroxylase 28
MnSOD 28
ERK1 28
interleukin-6 27
CO2 27
collagen 27
CYP 27
alcohol dehydrogenase 27
AKT 27
Catalase 27
CA1 27
thioredoxin reductase 26
alanine aminotransferase 26
GSTA1 26
aldehyde dehydrogenase 26
estrogen receptor 26
ferritin 25
NFE2L2 25
more...
Disease
cancer 905
tumor 408
GSH 408
carcinogenesis 295
hepatocellular carcinoma 214
breast cancer 126
lung cancer 85
Parkinson's disease 76
adenocarcinoma 76
carcinoma 70
diabetes 68
tumorigenesis 65
MCF 62
ischemia 58
colon cancer 58
leukemia 58
Alzheimer's disease 49
melanoma 42
neuroblastoma 42
colorectal cancer 40
NAME 38
non-small cell lung cancer 37
PCC 35
pheochromocytoma 35
prostate cancer 35
SDS 35
bladder cancer 33
tumor growth 32
squamous cell carcinoma 31
chemical carcinogenesis 28
acute myeloid leukemia 27
obesity 27
lung carcinoma 26
stroke 25
atherosclerosis 23
pancreatic cancer 23
DTD 21
cerebral ischemia 21
lymphoma 20
Huntington's disease 19
varices 18
hypertension 18
depression 18
renal disease 17
asthma 17
type 2 diabetes 17
acute lymphoblastic leukemia 17
AIN 16
Mycobacterium 16
liver cancer 16
hyperglycemia 16
cardiovascular disease 16
chronic obstructive pulmonary disease 16
myelodysplastic syndrome 15
diabetic nephropathy 15
childhood ALL 14
hepatoblastoma 14
skin cancer 14
colitis 14
tuberculosis 14
bovine leukemia 14
schizophrenia 14
liver cancer 13
macular degeneration 13
B-cell lymphoma 13
uterus 12
brain edema 12
cognitive impairment 12
XPD 12
heart failure 11
multiple sclerosis 11
cold 11
tumor progression 11
mole 11
myocardial ischemia 10
liver fibrosis 10
Krabbe disease 10
gastric cancer 10
mole 10
malnutrition 10
hemolytic anemia 10
liver disease 10
SEM 10
sepsis 9
metabolic syndrome 9
sepsis 9
amyotrophic lateral sclerosis 9
metastases 9
ovarian cancer 9
dysplasia 9
DBA 9
fatty liver 9
MAC 8
skin tumor 8
acute promyelocytic leukemia 8
adenoma 8
methemoglobinemia 8
bronchopulmonary dysplasia 8
neoplastic transformation 8
glioblastoma 8
solid tumor 8
inflammatory bowel disease 7
cholestasis 7
cholera 7
diabetic retinopathy 7
epididymis 7
mammary tumor 7
DIA 7
DDP 7
cervical cancer 7
rheumatoid arthritis 7
osteoporosis 7
acute pancreatitis 7
glioma 7
hepatitis 7
anemia 7
pulmonary fibrosis 7
neuropathy 7
dehydration 7
Steroids 7
plaque 7
ATM 7
renal cell carcinoma 7
myeloid leukemia 6
chronic myeloid leukemia 6
HIV 6
cornea 6
esophageal cancer 6
Lissauer 6
acute leukemia 6
influenza 6
parkinsonism 6
chronic granulomatous disease 6
Hepatocellular carcinoma 6
brain tumor 6
cardiomyopathy 6
iron overload 6
tumor initiation 6
fibrosarcoma 6
esophageal cancer 6
ulcerative colitis 6
cirrhosis 6
dementia 6
hyperlipidemia 6
pancreatitis 6
infertility 5
autoimmune disease 5
small cell lung cancer 5
aplastic anemia 5
coronary artery disease 5
Nonalcoholic fatty liver 5
cataract 5
myelosuppression 5
oral cancer 5
herpes simplex 5
malaria 5
epithelial ovarian cancer 5
Blocking 5
osteoarthritis 5
Leukemia 5
more...
Symptom
pain 31
hyperoxia 21
seizures 15
starvation 9
fatigue 9
anesthesia 9
functional recovery 8
diarrhea 6
respiratory distress 4
thinning 4
acidity 4
hepatomegaly 4
weakness 4
collapse 3
hypothermia 3
vomiting 3
dry eye 3
exhaustion 3
ataxia 2
nausea 2
constipation 2
menopausal symptoms 2
anorexia 2
memory loss 2
dyspnea 2
headache 2
analgesia 2
tachypnea 2
pallor 2
Involuntary Movement 2
stigma 1
hot flashes 1
orofacial pain 1
tonic-clonic seizure 1
hypotonia 1
urinary frequency 1
twitching 1
spasticity 1
nasal congestion 1
Mills 1
ACHE 1
agitation 1
eds 1
chronic constipation 1
erythema 1
ophthalmoplegia 1
abdominal pain 1
hemoptysis 1
lethargy 1
Decreased activity 1
ketonuria 1
cyanosis 1
anosmia 1
dry skin 1
abnormal gait 1
masculinization 1
disturbed balance 1
acute stress 1
cachexia 1
sleepiness 1
arthralgia 1
dystonia 1
overweight 1
myalgia 1
fasciculation 1
Drug
NADH 773
ROS 148
FAD 146
ascorbate 55
Vitamin K 44
Glutathione 31
Heme 22
vitamin E 21
lysine 18
Gel 15
Cardiovasc 13
Ethanol 10
caffeine 9
Adriamycin 9
Nitric Oxide 8
NBT 8
IL-2 7
Arsenic trioxide 7
Mutagen 7
Cibacron Blue 7
MAP 6
CTX 6
Glycyrrhiza 6
citric acid 6
Flavin 5
Bifidobacterium 5
Rutin 5
PCB 5
Dermatol 5
CTX 4
Monit 4
CTX 4
GEO 4
CSF 4
Captopril 4
BZQ 4
Idebenone 4
Vitamin E 4
CPT-11 4
BH4 4
L-tyrosine 3
Propofol 3
Fraction 3
Photofrin 3
MDS 3
DEX 3
Estrogens 3
IFN-gamma 3
Tannic acid 3
lactose 3
Nephron 3
Itraconazole 3
EE2 3
THF 3
Leaf 3
ZnO 2
DFP 2
CaCl2 2
Simvastatin 2
Fidarestat 2
Emodin 2
Ciprofibrate 2
Salicylate 2
CPR 2
Emodin 2
NVP 2
Taxol 2
ABC 2
Kainic acid 2
Ginseng 2
Aloe 2
EPA 2
niacin 2
Parkin 2
Riboflavin 2
CaCl2 2
CaCl2 2
ALA 2
Parkin 2
Fidarestat 2
TAK 2
FeCl3 2
Sodium nitroprusside 2
Atabrine 2
IL-1ra 2
Omeprazole 2
Paraffin 2
p75 2
Trifluoperazine 2
Duroquinone 2
DNase I 2
TAC 2
Premarin 2
ADR 2
Imatinib 2
PCP 2
Apomorphine 2
TTC 1
Motexafin gadolinium 1
ADM 1
Liraglutide 1
Roflumilast 1
Podophyllum 1
Desferal 1
Desferal 1
Safflower 1
Taxotere 1
CDX 1
Spectrum 1
Artemether 1
NaI 1
Nitazoxanide 1
Bexarotene 1
Methylene blue 1
Leucovorin 1
Geranium 1
PTC 1
Reserpine 1
Clonidine 1
Compound 16 1
Amiloride 1
Ethylenediamine 1
NaI 1
Dithranol 1
Malarone 1
Ranitidine 1
TES 1
Asn 1
Ouabain 1
Valproic Acid 1
PE2 1
Solon 1
NaI 1
Roflumilast 1
Fenbendazole 1
-deoxyadenosine 1
Indomethacin 1
Silica 1
BLM 1
ETS 1
Equilenin 1
Podophyllotoxin 1
GHRP 1
TEL 1
pyridoxal phosphate 1
Vanilla 1
Furan 1
Spectrum 1
Sorafenib 1
NAG 1
Amiloride 1
Vardenafil 1
Aminoguanidine 1
Apaziquone 1
Dextran sulfate sodium 1
Myricetin 1
Compound 15 1
Natalizumab 1
Alanine 1
NaI 1
more...
Enzyme
NQO1 6196
diaphorase 1952
NADPH-diaphorase 1903
diaphorase 1897
glutathione S-transferase 507
superoxide dismutase 490
catalase 429
NO synthase 256
glutathione peroxidase 255
glutathione reductase 191
peroxidase 155
heme oxygenase 152
lactate dehydrogenase 146
mitogen-activated protein kinase 129
complex I 122
CPR 119
luciferase 98
gamma-glutamylcysteine synthetase 95
acetylcholinesterase 87
glucose-6-phosphate dehydrogenase 86
succinate dehydrogenase 86
NQO2 83
ATPase 80
ERK 77
caspase-3 76
UDP-glucuronosyltransferase 73
NOS 72
alkaline phosphatase 69
xanthine oxidase 68
tyrosine hydroxylase 64
alanine aminotransferase 63
aspartate aminotransferase 62
NADH dehydrogenase 58
NADH-cytochrome b5 reductase 51
acid phosphatase 50
cytochrome oxidase 47
soluble epoxide hydrolase 47
choline acetyltransferase 46
adrenodoxin reductase 44
protein kinase 43
PARP 41
succinic dehydrogenase 41
alcohol dehydrogenase 40
aldehyde dehydrogenase 38
ornithine decarboxylase 38
proteasome 38
AMP-activated protein kinase 36
gamma-glutamyl transpeptidase 36
protein kinase C 36
demethylase 36
NADPH oxidase 35
microsomal epoxide hydrolase 33
ECH 33
aryl hydrocarbon hydroxylase 32
AST 31
NADPH oxidase 31
malate dehydrogenase 30
hydrogenase 29
hydrogenase 29
thioredoxin reductase 28
aldehyde dehydrogenase 27
nitrate reductase 26
aldehyde dehydrogenase 26
aldehyde dehydrogenase 26
aldehyde dehydrogenase 26
AMPK 25
AMPK 24
myrosinase 22
glycerol-3-phosphate dehydrogenase 22
glycerol-3-phosphate dehydrogenase 22
nitrate reductase 21
nitrate reductase 21
nitrate reductase 21
nitrate reductase 21
nitrate reductase 21
monoamine oxidase 20
tyrosinase 20
carbonyl reductase 20
topoisomerase 17
ACS 17
glucose-6-phosphatase 17
cysteine synthase 16
topoisomerase 15
GSK 15
aldose reductase 15
ATP synthase 15
reverse transcriptase 15
NADPH:quinone oxidoreductase 15
isocitrate dehydrogenase 14
chloramphenicol acetyltransferase 14
guanylate cyclase 14
CYP3A4 14
glucose dehydrogenase 14
glutamate dehydrogenase 14
MEK 14
transhydrogenase 14
fumarate reductase 14
phosphatidylinositol 3-kinase 13
glutamate dehydrogenase 13
glutamate dehydrogenase 13
phosphorylase 13
nitrite reductase 12
nitrite reductase 12
aldehyde oxidase 12
6-phosphogluconate dehydrogenase 12
nitrite reductase 12
6-phosphogluconate dehydrogenase 12
caspase-9 12
MPP 12
PAH 12
cholinesterase 12
P-glycoprotein 12
pyruvate dehydrogenase 11
flavin reductase 11
isocitrate dehydrogenase 11
IKK 11
lipase 11
peroxiredoxin 11
trypsin 11
focal adhesion kinase 10
N-acetyltransferase 10
HSD 10
phosphodiesterase 10
glutathione synthetase 10
beta-hydroxybutyrate dehydrogenase 10
methylenetetrahydrofolate reductase 9
azoreductase 9
dihydrodiol dehydrogenase 9
aldehyde reductase 9
phosphoglucose isomerase 9
aldehyde reductase 9
hexokinase 9
aldehyde reductase 9
aconitase 9
methylenetetrahydrofolate reductase 9
pyruvate dehydrogenase 8
carboxylesterase 8
xanthine dehydrogenase 8
caspase-1 8
phosphoglucomutase 8
pyruvate dehydrogenase 8
5'-nucleotidase 8
carbonic anhydrase 7
paraoxonase 7
leucine aminopeptidase 7
creatine kinase 7
ACE 7
formate dehydrogenase 7
lactic acid dehydrogenase 7
beta-glucuronidase 7
bidirectional hydrogenase 6
formate dehydrogenase 6
DNA methyltransferase 6
RNA polymerase 6
lactic acid dehydrogenase 6
glucose oxidase 6
collagenase 6
ceruloplasmin 6
nitrogenase 6
sulfatase 6
more...
Compound
NAD 1102
NAD 1039
nicotinamide 882
NADPH 867
NADPH 865
phosphate 863
oxygen 808
NADH 770
DNA 677
nitric oxide 563
Dec 451
GSH 426
GSH 426
NADP 313
hydrogen 239
water 188
sodium 169
glucose 163
cysteine 150
FAD 147
arginine 140
hydroquinone 139
pyrene 133
TNF 126
iron 123
ATP 116
MDA 107
H2O2 105
naphthoquinone 101
naphthoquinone 101
naphthoquinone 101
naphthoquinone 101
naphthoquinone 101
naphthoquinone 101
naphthoquinone 101
nitrogen 97
Clin 96
ethanol 92
calcium 91
benzene 90
glutamate 82
ubiquinone 79
CAT 77
CAT 77
CAT 77
BHC 76
sulfate 73
UDP 71
acetate 70
FMN 67
pyridine 67
salt 62
N-acetylcysteine 56
CO2 56
GSSG 54
Quinone 52
MTT 52
anthracene 51
His 51
cyanide 47
urea 45
creatinine 45
galactose 40
bromide 37
Sulforaphane 37
SDS 37
nitrate 36
ammonium 35
zinc 35
aldehyde 35
cadmium 35
MMC 35
Menadione 34
copper 34
tyrosine 33
leucine 31
methionine 31
alcohol dehydrogenase 30
selenium 30
aldehyde 29
alanine 29
serine 29
lysine 29
methanol 29
8-OHdG 28
DBA 28
indole-3-carbinol 28
potassium 27
manganese 27
DTT 26
Benzene 25
Triton X-100 25
ADP 25
uridine 25
CB 1954 24
pentose 24
CoQ 23
ADP 23
pentose 23
pentose 23
pentose 23
ADP 23
1-chloro-2,4-dinitrobenzene 23
Resveratrol 23
superoxide radical 23
H2S 22
Heme 22
aflatoxin B1 22
APAP 22
Phe 21
Ferredoxin 21
chalcone 21
ethyl acetate 21
AMP 21
Neuronal 21
cGMP 20
hydroxylamine 20
silver 20
hydroxylamine 20
coenzyme Q10 20
tert-butyl hydroperoxide 19
EDTA 19
EDTA 19
GABA 19
DDP 18
phenol 18
Adriamycin 18
glycerol 18
Curcumin 18
DEAE 18
ubiquinol 18
GABA 18
Gly 17
quinoline 17
quinoline 17
ACS 17
H2S 17
ACS 17
Pac 16
BHA 16
tryptophan 16
tryptophan 16
tryptophan 16
Melatonin 16
tryptophan 16
aniline 16
Panam 15
NH2 15
threonine 15
glucose-6-phosphate 15
MPTP 15
gamma-aminobutyric acid 14
5-HT 14
CoA 14
dihydrolipoamide 14
Warfarin 14
1H-indole 14
PEG 14
2-nonenal 14
Estrogen 13
more...