Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.6.3.1 (
NADPH oxidase
)
11,281
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
NADPH
1222
superoxide dismutase
968
p47
929
Mol
810
catalase
733
Sep
725
ROS
696
p47phox
611
angiotensin II
594
nitric oxide synthase
575
p22phox
545
NOX2
511
p38
463
p22
461
Ang II
436
xanthine oxidase
432
cytokine
418
p67
417
MAPK
378
NOX4
360
ERK1
356
inducible nitric oxide synthase
356
TNF
338
insulin
331
lipopolysaccharide
315
myeloperoxidase
304
p67phox
291
NADH
288
tumor necrosis factor
287
caspase-3
272
NAD
251
SOD
249
renin
249
DPI
248
ATP
246
collagen
237
peroxidase
234
GSH
231
membrane-bound
230
PKC
216
ERK
208
IL-6
204
JNK
200
glutathione peroxidase
200
NOX1
198
GTP
191
cytochrome c
191
endothelial nitric oxide synthase
190
eNOS
182
p47-phox
168
NADPH oxidase 2
162
cytochrome b
157
endoplasmic reticulum
156
X-linked
155
p67-phox
155
p40
150
LPS
148
dual oxidase
147
Rho
145
mitogen-activated protein
137
heme oxygenase-1
136
p65
136
GTPase
132
PI3K
130
TNF-alpha
129
reductase
129
extracellular signal-regulated kinase
126
tyrosine kinase
124
FAD
123
TLR4
121
cyclooxygenase
120
cytochrome
118
AT1
114
ANG
111
small GTPase
111
flavoprotein
106
Bcl-2
106
p40phox
104
ATPase
101
p38 mitogen-activated protein kinase
100
more...
Disease
hypertension
846
diabetes
606
atherosclerosis
533
chronic granulomatous disease
508
cancer
401
ischemia
301
tumor
238
GSH
231
cardiovascular disease
226
stroke
200
heart failure
197
hyperglycemia
169
Alzheimer's disease
160
obesity
159
NAME
145
diabetic nephropathy
131
type 2 diabetes
126
Parkinson's disease
120
immunodeficiency
119
ATM
117
sepsis
102
renal disease
101
vascular disease
99
sepsis
96
metabolic syndrome
92
myocardial infarction
90
proteinuria
88
plaque
80
carcinogenesis
73
cerebral ischemia
72
pertussis
69
infectious diseases
62
rheumatoid arthritis
61
hypercholesterolemia
59
pulmonary hypertension
59
Mycobacterium
58
leukemia
58
asthma
56
SDS
54
glomerulosclerosis
54
hepatocellular carcinoma
54
arthritis
53
inflammatory bowel disease
50
HIV
48
myocardial ischemia
47
cognitive impairment
47
Endothelial dysfunction
46
coronary artery disease
45
Blocking
45
tumor progression
43
Infection
42
ventricular hypertrophy
42
CGD
42
tuberculosis
41
pneumonia
41
breast cancer
41
tumorigenesis
40
depression
38
dementia
38
colitis
38
tumor growth
37
bacterial infection
37
hyperhomocysteinemia
36
Epstein
36
adenocarcinoma
36
neuroblastoma
36
type 1 diabetes
35
diabetic retinopathy
34
melanoma
34
prostate cancer
34
liver fibrosis
34
renal failure
33
cold
33
hyperlipidemia
32
cystic fibrosis
32
multiple sclerosis
32
carcinoma
30
fatty liver
30
cardiomyopathy
30
chronic obstructive pulmonary disease
29
more...
Symptom
pain
44
hyperoxia
32
anesthesia
31
starvation
20
collapse
17
seizures
17
diarrhea
14
respiratory distress
13
weakness
11
exhaustion
10
functional recovery
8
skin damage
8
overweight
7
angina
6
acidity
6
fatigue
5
HSA
4
hypothermia
4
Macula
4
splenomegaly
3
cough
3
cachexia
3
headache
3
analgesia
3
chills
2
chest pain
2
abdominal pain
2
impaired motor coordination
2
thinning
2
tremor
2
acute stress
2
sleepiness
2
dyspnea
2
hypercapnia
2
muscle cramps
1
Anoxia
1
orofacial pain
1
hyperesthesia
1
insomnia
1
Neuropathic pain
1
colic
1
nausea
1
numbness
1
scaly skin
1
constipation
1
adenitis
1
DNA marker
1
POA
1
shortness of breath
1
erythema
1
hepatosplenomegaly
1
low back pain
1
limb pain
1
memory loss
1
pelvic pain
1
polyuria
1
vomiting
1
cancer pain
1
rhinorrhea
1
microbial colonization
1
Noise-induced hearing loss
1
spasm
1
tachypnea
1
bradykinesia
1
Drug
ROS
696
NADH
286
Angiotensin II
180
FAD
123
ascorbate
110
Cardiovasc
98
IFN-gamma
58
vitamin E
53
Indomethacin
48
MAP
42
CSF
40
lysine
39
Heme
30
BH4
30
nitroglycerin
28
Ethanol
25
Nitric Oxide
23
NBT
23
Gel
18
Photofrin
18
Dermatol
17
ETA
14
ICI
13
DNase I
12
Glutathione
12
Leaf
11
Histamine
9
IL-2
9
Nebivolol
8
ENT
8
Bifidobacterium
8
Capsicum
7
niacin
7
CAM
7
Simvastatin
7
caffeine
6
Asthma
6
Albumin
6
Glucagon
6
Arsenic trioxide
6
Forskolin
6
p75
5
Olmesartan
5
ACT
5
Epigallocatechin
5
Aminoguanidine
5
Monit
5
Nephron
5
TAT
5
CoCl2
5
Fluorescein
5
Captopril
5
Pravastatin
5
CoCl2
5
Fructose
5
Propofol
5
ALA
4
Aliskiren
4
Desferal
4
Vitamin E
4
TAK
4
Valsartan
4
Adenosine triphosphate
4
Rosuvastatin
4
Desferal
4
Spectrum
4
Rosiglitazone
4
G-CSF
4
Asn
4
ZnCl2
4
ZnCl2
4
Prednisolone
3
TiO2
3
Cibacron Blue
3
Emodin
3
Tocopherol
3
CCL
3
IFN-beta
3
Fenoldopam
3
TMS
3
more...
Enzyme
NADPH oxidase
11281
NADPH oxidase
10176
superoxide dismutase
1153
mitogen-activated protein kinase
1072
catalase
749
protein kinase C
746
peroxidase
546
xanthine oxidase
441
NO synthase
326
protein kinase
322
ERK
288
renin
249
glutathione peroxidase
209
caspase-3
206
MEK
123
phospholipase A2
118
NOS
116
ATPase
113
phospholipase C
107
glutathione reductase
96
complex I
91
phosphatidylinositol 3-kinase
91
phospholipase D
81
focal adhesion kinase
78
AMP-activated protein kinase
71
ascorbate peroxidase
69
ACE
67
lactate dehydrogenase
65
glucose-6-phosphate dehydrogenase
62
diaphorase
61
luciferase
59
thrombin
54
heme oxygenase
53
caspase-1
53
lipoxygenase
51
PARP
51
CPR
51
tyrosine hydroxylase
42
calcineurin
41
elastase
41
phosphoinositide 3-kinase
40
DCF
40
MAP
40
AMPK
37
phosphodiesterase
37
neutrophil elastase
37
peroxiredoxin
35
thioredoxin reductase
33
IKK
32
glutathione S-transferase
32
reverse transcriptase
32
proteasome
32
NQO1
31
AMPK
31
guanylate cyclase
29
NADPH-diaphorase
28
thyroid peroxidase
28
caspase-9
28
xanthine dehydrogenase
27
adenylate cyclase
26
alkaline phosphatase
26
alanine aminotransferase
25
trypsin
25
arginase
24
lysozyme
24
glucose oxidase
22
collagenase
22
aspartate aminotransferase
21
caspase-8
19
succinate dehydrogenase
18
6-phosphogluconate dehydrogenase
17
CaMKII
17
12-lipoxygenase
17
6-phosphogluconate dehydrogenase
17
RNA polymerase
17
diaphorase
17
nitrate reductase
16
nitrate reductase
16
nitrate reductase
16
demethylase
16
more...
Compound
oxygen
5604
NADPH
1224
NADPH
1222
nitric oxide
1013
hydrogen
891
Dec
792
calcium
782
phosphate
674
H2O2
642
acetate
641
glucose
627
nicotinamide
583
DNA
583
sodium
366
superoxide radical
357
Clin
352
cysteine
342
TNF
338
water
335
Ang II
323
tyrosine
302
NADH
287
Phe
283
arginine
270
NAD
259
N-acetylcysteine
257
NAD
251
DPI
248
ATP
248
nitrogen
247
GSH
241
GSH
241
salt
230
PMA
218
PMA
215
Angiotensin II
209
Apocynin
203
GTP
191
iron
157
NADP
154
leucine
143
diacetate
132
serine
129
ethanol
129
sulfate
125
FAD
124
cAMP
122
aldosterone
119
methionine
114
glutamate
103
potassium
100
cGMP
96
Cardiol
94
zinc
93
THP
91
THP
89
nitrate
89
PEG
89
galactose
77
Panam
75
creatinine
74
AMP
71
GDP
71
cyanide
69
Tempol
69
ADP
68
threonine
68
iodine
66
ADP
63
ADP
63
CO2
62
copper
61
SDS
60
manganese
59
Insulin
59
GSSG
59
ACh
58
8-OHdG
58
salicylic acid
57
lysine
56
more...