Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.6.3.1 (NADPH oxidase)
11,281 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
NADPH 1222
superoxide dismutase 968
p47 929
Mol 810
catalase 733
Sep 725
ROS 696
p47phox 611
angiotensin II 594
nitric oxide synthase 575
p22phox 545
NOX2 511
p38 463
p22 461
Ang II 436
xanthine oxidase 432
cytokine 418
p67 417
MAPK 378
NOX4 360
ERK1 356
inducible nitric oxide synthase 356
TNF 338
insulin 331
lipopolysaccharide 315
myeloperoxidase 304
p67phox 291
NADH 288
tumor necrosis factor 287
caspase-3 272
NAD 251
renin 249
SOD 249
DPI 248
ATP 246
collagen 237
peroxidase 234
GSH 231
membrane-bound 230
PKC 216
more...
Disease
hypertension 846
diabetes 606
atherosclerosis 533
chronic granulomatous disease 508
cancer 401
ischemia 301
tumor 238
GSH 231
cardiovascular disease 226
stroke 200
heart failure 197
hyperglycemia 169
Alzheimer's disease 160
obesity 159
NAME 145
diabetic nephropathy 131
type 2 diabetes 126
Parkinson's disease 120
immunodeficiency 119
ATM 117
sepsis 102
renal disease 101
vascular disease 99
sepsis 96
metabolic syndrome 92
myocardial infarction 90
proteinuria 88
plaque 80
carcinogenesis 73
cerebral ischemia 72
pertussis 69
infectious diseases 62
rheumatoid arthritis 61
pulmonary hypertension 59
hypercholesterolemia 59
leukemia 58
Mycobacterium 58
asthma 56
hepatocellular carcinoma 54
glomerulosclerosis 54
more...
Symptom
pain 44
hyperoxia 32
anesthesia 31
starvation 20
seizures 17
collapse 17
diarrhea 14
respiratory distress 13
weakness 11
exhaustion 10
skin damage 8
functional recovery 8
overweight 7
angina 6
acidity 6
fatigue 5
hypothermia 4
HSA 4
Macula 4
splenomegaly 3
cachexia 3
analgesia 3
cough 3
headache 3
chills 2
chest pain 2
abdominal pain 2
thinning 2
dyspnea 2
tremor 2
sleepiness 2
acute stress 2
impaired motor coordination 2
hypercapnia 2
muscle cramps 1
Anoxia 1
orofacial pain 1
hyperesthesia 1
insomnia 1
Neuropathic pain 1
more...
Drug
ROS 696
NADH 286
Angiotensin II 180
FAD 123
ascorbate 110
Cardiovasc 98
IFN-gamma 58
vitamin E 53
Indomethacin 48
MAP 42
CSF 40
lysine 39
BH4 30
Heme 30
nitroglycerin 28
Ethanol 25
Nitric Oxide 23
NBT 23
Gel 18
Photofrin 18
Dermatol 17
ETA 14
ICI 13
DNase I 12
Glutathione 12
Leaf 11
IL-2 9
Histamine 9
Bifidobacterium 8
Nebivolol 8
ENT 8
Simvastatin 7
CAM 7
niacin 7
Capsicum 7
Arsenic trioxide 6
Albumin 6
Asthma 6
Glucagon 6
Forskolin 6
more...
Enzyme
NADPH oxidase 11281
NADPH oxidase 10176
superoxide dismutase 1153
mitogen-activated protein kinase 1072
catalase 749
protein kinase C 746
peroxidase 546
xanthine oxidase 441
NO synthase 326
protein kinase 322
ERK 288
renin 249
glutathione peroxidase 209
caspase-3 206
MEK 123
phospholipase A2 118
NOS 116
ATPase 113
phospholipase C 107
glutathione reductase 96
complex I 91
phosphatidylinositol 3-kinase 91
phospholipase D 81
focal adhesion kinase 78
AMP-activated protein kinase 71
ascorbate peroxidase 69
ACE 67
lactate dehydrogenase 65
glucose-6-phosphate dehydrogenase 62
diaphorase 61
luciferase 59
thrombin 54
heme oxygenase 53
caspase-1 53
PARP 51
CPR 51
lipoxygenase 51
tyrosine hydroxylase 42
elastase 41
calcineurin 41
more...
Compound
oxygen 5604
NADPH 1224
NADPH 1222
nitric oxide 1013
hydrogen 891
Dec 792
calcium 782
phosphate 674
H2O2 642
acetate 641
glucose 627
DNA 583
nicotinamide 583
sodium 366
superoxide radical 357
Clin 352
cysteine 342
TNF 338
water 335
Ang II 323
tyrosine 302
NADH 287
Phe 283
arginine 270
NAD 259
N-acetylcysteine 257
NAD 251
ATP 248
DPI 248
nitrogen 247
GSH 241
GSH 241
salt 230
PMA 218
PMA 215
Angiotensin II 209
Apocynin 203
GTP 191
iron 157
NADP 154
more...