Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.6.3.1 (
NADPH oxidase
)
11,281
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
NADPH
1222
superoxide dismutase
968
p47
929
Mol
810
catalase
733
Sep
725
ROS
696
p47phox
611
angiotensin II
594
nitric oxide synthase
575
p22phox
545
NOX2
511
p38
463
p22
461
Ang II
436
xanthine oxidase
432
cytokine
418
p67
417
MAPK
378
NOX4
360
ERK1
356
inducible nitric oxide synthase
356
TNF
338
insulin
331
lipopolysaccharide
315
myeloperoxidase
304
p67phox
291
NADH
288
tumor necrosis factor
287
caspase-3
272
NAD
251
renin
249
SOD
249
DPI
248
ATP
246
collagen
237
peroxidase
234
GSH
231
membrane-bound
230
PKC
216
more...
Disease
hypertension
846
diabetes
606
atherosclerosis
533
chronic granulomatous disease
508
cancer
401
ischemia
301
tumor
238
GSH
231
cardiovascular disease
226
stroke
200
heart failure
197
hyperglycemia
169
Alzheimer's disease
160
obesity
159
NAME
145
diabetic nephropathy
131
type 2 diabetes
126
Parkinson's disease
120
immunodeficiency
119
ATM
117
sepsis
102
renal disease
101
vascular disease
99
sepsis
96
metabolic syndrome
92
myocardial infarction
90
proteinuria
88
plaque
80
carcinogenesis
73
cerebral ischemia
72
pertussis
69
infectious diseases
62
rheumatoid arthritis
61
pulmonary hypertension
59
hypercholesterolemia
59
leukemia
58
Mycobacterium
58
asthma
56
hepatocellular carcinoma
54
glomerulosclerosis
54
more...
Symptom
pain
44
hyperoxia
32
anesthesia
31
starvation
20
seizures
17
collapse
17
diarrhea
14
respiratory distress
13
weakness
11
exhaustion
10
skin damage
8
functional recovery
8
overweight
7
angina
6
acidity
6
fatigue
5
hypothermia
4
HSA
4
Macula
4
splenomegaly
3
cachexia
3
analgesia
3
cough
3
headache
3
chills
2
chest pain
2
abdominal pain
2
thinning
2
dyspnea
2
tremor
2
sleepiness
2
acute stress
2
impaired motor coordination
2
hypercapnia
2
muscle cramps
1
Anoxia
1
orofacial pain
1
hyperesthesia
1
insomnia
1
Neuropathic pain
1
more...
Drug
ROS
696
NADH
286
Angiotensin II
180
FAD
123
ascorbate
110
Cardiovasc
98
IFN-gamma
58
vitamin E
53
Indomethacin
48
MAP
42
CSF
40
lysine
39
BH4
30
Heme
30
nitroglycerin
28
Ethanol
25
Nitric Oxide
23
NBT
23
Gel
18
Photofrin
18
Dermatol
17
ETA
14
ICI
13
DNase I
12
Glutathione
12
Leaf
11
IL-2
9
Histamine
9
Bifidobacterium
8
Nebivolol
8
ENT
8
Simvastatin
7
CAM
7
niacin
7
Capsicum
7
Arsenic trioxide
6
Albumin
6
Asthma
6
Glucagon
6
Forskolin
6
more...
Enzyme
NADPH oxidase
11281
NADPH oxidase
10176
superoxide dismutase
1153
mitogen-activated protein kinase
1072
catalase
749
protein kinase C
746
peroxidase
546
xanthine oxidase
441
NO synthase
326
protein kinase
322
ERK
288
renin
249
glutathione peroxidase
209
caspase-3
206
MEK
123
phospholipase A2
118
NOS
116
ATPase
113
phospholipase C
107
glutathione reductase
96
complex I
91
phosphatidylinositol 3-kinase
91
phospholipase D
81
focal adhesion kinase
78
AMP-activated protein kinase
71
ascorbate peroxidase
69
ACE
67
lactate dehydrogenase
65
glucose-6-phosphate dehydrogenase
62
diaphorase
61
luciferase
59
thrombin
54
heme oxygenase
53
caspase-1
53
PARP
51
CPR
51
lipoxygenase
51
tyrosine hydroxylase
42
elastase
41
calcineurin
41
more...
Compound
oxygen
5604
NADPH
1224
NADPH
1222
nitric oxide
1013
hydrogen
891
Dec
792
calcium
782
phosphate
674
H2O2
642
acetate
641
glucose
627
DNA
583
nicotinamide
583
sodium
366
superoxide radical
357
Clin
352
cysteine
342
TNF
338
water
335
Ang II
323
tyrosine
302
NADH
287
Phe
283
arginine
270
NAD
259
N-acetylcysteine
257
NAD
251
ATP
248
DPI
248
nitrogen
247
GSH
241
GSH
241
salt
230
PMA
218
PMA
215
Angiotensin II
209
Apocynin
203
GTP
191
iron
157
NADP
154
more...