Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.6.3.1 (NADPH oxidase)
 11,281 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
NADPH 1222
superoxide dismutase 968
p47 929
Mol 810
catalase 733
Sep 725
ROS 696
p47phox 611
angiotensin II 594
nitric oxide synthase 575
p22phox 545
NOX2 511
p38 463
p22 461
Ang II 436
xanthine oxidase 432
cytokine 418
p67 417
MAPK 378
NOX4 360
more...
Disease
hypertension 846
diabetes 606
atherosclerosis 533
chronic granulomatous disease 508
cancer 401
ischemia 301
tumor 238
GSH 231
cardiovascular disease 226
stroke 200
heart failure 197
hyperglycemia 169
Alzheimer's disease 160
obesity 159
NAME 145
diabetic nephropathy 131
type 2 diabetes 126
Parkinson's disease 120
immunodeficiency 119
ATM 117
more...
Symptom
pain 44
hyperoxia 32
anesthesia 31
starvation 20
seizures 17
collapse 17
diarrhea 14
respiratory distress 13
weakness 11
exhaustion 10
functional recovery 8
skin damage 8
overweight 7
angina 6
acidity 6
fatigue 5
hypothermia 4
Macula 4
HSA 4
analgesia 3
more...
Drug
ROS 696
NADH 286
Angiotensin II 180
FAD 123
ascorbate 110
Cardiovasc 98
IFN-gamma 58
vitamin E 53
Indomethacin 48
MAP 42
CSF 40
lysine 39
BH4 30
Heme 30
nitroglycerin 28
Ethanol 25
Nitric Oxide 23
NBT 23
Photofrin 18
Gel 18
more...
Enzyme
NADPH oxidase 11281
NADPH oxidase 10176
superoxide dismutase 1153
mitogen-activated protein kinase 1072
catalase 749
protein kinase C 746
peroxidase 546
xanthine oxidase 441
NO synthase 326
protein kinase 322
ERK 288
renin 249
glutathione peroxidase 209
caspase-3 206
MEK 123
phospholipase A2 118
NOS 116
ATPase 113
phospholipase C 107
glutathione reductase 96
more...
Compound
oxygen 5604
NADPH 1224
NADPH 1222
nitric oxide 1013
hydrogen 891
Dec 792
calcium 782
phosphate 674
H2O2 642
acetate 641
glucose 627
DNA 583
nicotinamide 583
sodium 366
superoxide radical 357
Clin 352
cysteine 342
TNF 338
water 335
Ang II 323
more...