Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.6.3.1 (
NADPH oxidase
)
11,281
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
In higher plants under low oxygen or hypoxic conditions, the phytohormone ethylene and hydrogen peroxide (H
2
O
2
) are involved in complex regulatory mechanisms in hypoxia signaling pathways. The respiratory burst oxidase homolog D (RbohD), an
NADPH oxidase
, is involved in the primary stages of hypoxia signaling, modulating the expression of downstream hypoxia-inducible genes under hypoxic stress. In this study, our data revealed that under normoxic conditions, seed germination was delayed in the
rbohD
/
ein2-5
double mutant, whereas postgermination stage root growth was promoted. Under submergence, the
rbohD/ein2-5
double mutant line had an inhibited root growth phenotype. Furthermore, chlorophyll content and leaf survival were reduced in the
rbohD/ein2-5
double mutant compared with wild-type plants under submerged conditions. In quantitative RT-PCR analysis, the induction of
Ethylene-responsive factor 73
/
hypoxia responsive 1
(
AtERF73/HRE1
) and
alcohol dehydrogenase 1
(
AtADH1
) transcripts was lower in the
rbohD/ein2-5
double mutant during hypoxic stress than in wild-type plants and in
rbohD
and
ein2-5
mutant lines. Taken together, our results indicate that an interplay of ethylene and RbohD is involved in regulating seed germination and post-germination stages under normoxic conditions. Moreover, ethylene and RbohD are involved in modulating seedling root growth, leaf chlorophyll content, and hypoxia-inducible gene expression under hypoxic conditions.
...
PMID:NADPH Oxidase RbohD and Ethylene Signaling are Involved in Modulating Seedling Growth and Survival Under Submergence Stress. 3227 72
