Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:1.5.7.1 (methylenetetrahydrofolate reductase)
2,116 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein methylenetetrahydrofolate reductase 2013 5,10-methylenetetrahydrofolate reductase 299 MTHFR 230 prothrombin 193 Mol 172 B12 164 factor V Leiden 162 Sep 151 methionine synthase 150 methionine synthase reductase 94 factor V 87 MTRR 83 thymidylate synthase 82 MTR 71 protein C 63 cystathionine beta-synthase 63 protein S 56 plasminogen activator inhibitor-1 53 reduced folate carrier 45 plasminogen activator inhibitor 40 fibrinogen 33 antithrombin 33 methylenetetrahydrofolate dehydrogenase 33 apolipoprotein E 27 methyltransferase 26 reductase 25 dihydrofolate reductase 24 antithrombin III 23 Methylenetetrahydrofolate reductase 23 CBS 23 insulin 21 Polymerase 20 C-reactive protein 18 serine hydroxymethyltransferase 17 She 17 factor VIII 17 dihydropyrimidine dehydrogenase 17 glutathione S-transferase 17 UTR 17 glycoprotein 16 more...

Disease hyperhomocysteinemia 327 cancer 234 stroke 163 cardiovascular disease 125 atherosclerosis 92 vascular disease 92 coronary artery disease 85 hypertension 83 colorectal cancer 75 tumor 69 acute lymphoblastic leukemia 59 folate deficiency 58 breast cancer 58 diabetes 58 carcinogenesis 56 homocystinuria 54 schizophrenia 53 myocardial infarction 48 deep vein thrombosis 39 preeclampsia 38 Down syndrome 35 Alzheimer's disease 35 systemic lupus erythematosus 34 abortion 32 lupus 31 lymphoma 31 renal disease 30 lupus 30 obesity 27 childhood ALL 27 rheumatoid arthritis 25 dementia 25 migraine 24 gastric cancer 22 pulmonary embolism 22 leukemia 21 Thrombophilia 20 coronary heart disease 20 osteoporosis 19 colon cancer 19 more...

Symptom headache 18 seizures 15 overweight 10 pain 8 fatigue 5 abdominal pain 5 hypotonia 5 ataxia 5 weakness 5 vomiting 5 nausea 4 angina 4 tremor 4 spasticity 3 paraparesis 3 spasm 3 dysarthria 3 chest pain 2 numbness 2 dyspnea 2 cough 2 metamorphopsia 1 hemoptysis 1 anesthesia 1 hand pain 1 hypothermia 1 limb pain 1 photophobia 1 insomnia 1 cyanosis 1 hepatomegaly 1 anorexia 1 hypertonia 1 diarrhea 1 photopsia 1 dizziness 1 memory loss 1 inanition 1 Decreased activity 1 hemiplegia 1 more...

Drug THF 26 FAD 15 Vitamin B12 15 Cardiovasc 10 NADH 10 pyridoxal phosphate 9 CSF 6 Vitamin B 5 lysine 5 Monit 4 Fragment 4 vitamin E 3 Cobalamin 3 ascorbate 3 Nephron 3 Dermatol 2 CTX 2 Bevacizumab 2 Hakka 2 Nephron 2 Folic Acid 2 CTX 1 CTA 1 DDAVP 1 Gemfibrozil 1 MDS 1 Asn 1 CTX 1 Indomethacin 1 GVG 1 DDAVP 1 Fluorescein 1 Ethanol 1 Arsenic trioxide 1 Lamisil 1 IL-2 1 AZT 1 Oxaliplatin 1 Portal 1 Fluorescein 1 more...

Enzyme methylenetetrahydrofolate reductase 2116 methylenetetrahydrofolate reductase 2116 methionine synthase 152 methionine synthase 147 methionine synthase reductase 89 thymidylate synthase 83 APC 80 cystathionine beta-synthase 63 methylenetetrahydrofolate dehydrogenase 33 methylenetetrahydrofolate dehydrogenase 26 dihydrofolate reductase 25 ACE 22 serine hydroxymethyltransferase 19 glutathione S-transferase 18 homocysteine methyltransferase 18 dihydropyrimidine dehydrogenase 17 cyclohydrolase 16 dihydropyrimidine dehydrogenase 15 methionine adenosyltransferase 14 formyltetrahydrofolate synthetase 13 thrombin 12 NQO1 9 thiopurine methyltransferase 8 aldehyde dehydrogenase 8 aldehyde dehydrogenase 7 tissue plasminogen activator 7 ERK 7 aldehyde dehydrogenase 7 aldehyde dehydrogenase 7 aldehyde dehydrogenase 7 betaine-homocysteine methyltransferase 6 aspartate aminotransferase 6 glutathione reductase 5 paraoxonase 5 cystathionine gamma-synthase 5 phosphatidylethanolamine N-methyltransferase 5 calcineurin 5 paraoxonase 5 thymidine phosphorylase 4 folylpolyglutamate synthetase 4 more...

Compound homocysteine 780 DNA 337 methionine 241 Dec 164 Clin 160 PGA 127 Homocysteine 83 Homocysteine 83 adenosylmethionine 71 betaine 46 alanine 44 creatinine 37 valine 27 Cardiol 25 CBS 23 S-adenosylhomocysteine 22 water 21 glucose 21 cysteine 20 Methotrexate 20 serine 19 oxygen 18 FAD 16 His 14 NADPH 14 NADPH 14 nitric oxide 13 Pac 12 calcium 12 CH3-THF 12 sodium 11 phosphate 11 acetate 11 Methionine 10 glutamate 10 NADH 10 TMP 9 5,10-methenyltetrahydrofolate 9 5-FU 8 urea 8 more...

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