Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:1.5.7.1 (methylenetetrahydrofolate reductase)
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Human Gene/Protein
methylenetetrahydrofolate reductase 0.950
5,10-methylenetetrahydrofolate reductase 0.141
methionine synthase reductase 0.018
MTHFR 0.017
methionine synthase 0.012
factor V Leiden 0.007
MTR 0.005
MTRR 0.005
cystathionine beta-synthase 0.003
methylenetetrahydrofolate dehydrogenase 0.003
reduced folate carrier 0.002
5-methyltetrahydrofolate-homocysteine methyltransferase 0.002
factor V 0.002
B12 0.001
prothrombin 0.001
MTHFD1 0.001
thymidylate synthase 0.001
cystathionine-beta-synthase 0.001
Methylenetetrahydrofolate reductase 0.001
serine hydroxymethyltransferase 1 0.001
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Disease
hyperhomocysteinemia 0.016
homocystinuria 0.002
folate deficiency 0.001
Dihydrofolate reductase deficiency 0.000
methionine synthase deficiency 0.000
CBS deficiency 0.000
Thrombophilia 0.000
Factor II mutation 0.000
adult meningioma 0.000
glutamate formiminotransferase deficiency 0.000
Factor V Leiden mutation 0.000
vascular disease 0.000
Mesenteric infarction 0.000
Activated protein C resistance 0.000
Placental infarction 0.000
homocystinemia 0.000
childhood ALL 0.000
vitamin B12 deficiency 0.000
cardiovascular disease 0.000
NFLD 0.000
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Symptom
Livedoid 0.000
photopsia 0.000
hand pain 0.000
inanition 0.000
metamorphopsia 0.000
Decreased activity 0.000
headache 0.000
hypotonia 0.000
limb pain 0.000
paraparesis 0.000
overweight 0.000
dysarthria 0.000
hypertonia 0.000
seizures 0.000
photophobia 0.000
spasticity 0.000
ataxia 0.000
spasm 0.000
numbness 0.000
pallor 0.000
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Drug
Vitamin B12 0.000
Folic Acid 0.000
Hakka 0.000
THF 0.000
Cobalamin 0.000
Lamisil 0.000
Lamisil 0.000
FAD 0.000
pyridoxal phosphate 0.000
Deoxyadenosine 0.000
Vitamin B 0.000
GVG 0.000
Pyridoxal 0.000
Gemfibrozil 0.000
Fragment 0.000
Pemetrexed 0.000
Leucovorin 0.000
Troglitazone 0.000
NADH 0.000
Riboflavin 0.000
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Enzyme
methylenetetrahydrofolate reductase 0.999
methylenetetrahydrofolate reductase 0.991
methionine synthase reductase 0.019
methionine synthase 0.012
methionine synthase 0.012
methylenetetrahydrofolate dehydrogenase 0.004
methylenetetrahydrofolate dehydrogenase 0.003
cystathionine beta-synthase 0.002
homocysteine methyltransferase 0.001
thymidylate synthase 0.001
formyltetrahydrofolate synthetase 0.001
serine hydroxymethyltransferase 0.000
cyclohydrolase 0.000
5,10-methenyltetrahydrofolate synthetase 0.000
APC 0.000
methionine adenosyltransferase 0.000
dihydropyrimidine dehydrogenase 0.000
betaine-homocysteine methyltransferase 0.000
dihydropyrimidine dehydrogenase 0.000
10-formyltetrahydrofolate dehydrogenase 0.000
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Compound
homocysteine 0.025
Homocysteine 0.003
Homocysteine 0.003
PGA 0.002
methionine 0.000
CH3-THF 0.000
Menoctone 0.000
adenosylmethionine 0.000
5,10-methenyltetrahydrofolate 0.000
betaine 0.000
S-adenosylhomocysteine 0.000
CBS 0.000
5-formyltetrahydrofolate 0.000
DNA 0.000
dUMP 0.000
Diamant 0.000
Methotrexate 0.000
Thiouracil 0.000
Tetrahydrocurcumin 0.000
Methionine 0.000
more...