Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.5.7.1 (methylenetetrahydrofolate reductase)
 2,116 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
methylenetetrahydrofolate reductase 0.950
5,10-methylenetetrahydrofolate reductase 0.141
methionine synthase reductase 0.018
MTHFR 0.017
methionine synthase 0.012
factor V Leiden 0.007
MTR 0.005
MTRR 0.005
cystathionine beta-synthase 0.003
methylenetetrahydrofolate dehydrogenase 0.003
reduced folate carrier 0.002
5-methyltetrahydrofolate-homocysteine methyltransferase 0.002
factor V 0.002
B12 0.001
prothrombin 0.001
MTHFD1 0.001
thymidylate synthase 0.001
cystathionine-beta-synthase 0.001
Methylenetetrahydrofolate reductase 0.001
serine hydroxymethyltransferase 1 0.001
SLC19A1 0.001
adrenergic, beta-3-, receptor 0.001
CDK5 regulatory subunit associated protein 1 0.001
cholesteryl ester transfer protein, plasma 0.001
RFC1 0.001
cytoplasmic serine hydroxymethyltransferase 0.000
intrinsic factor-vitamin B12 receptor 0.000
methylenetetrahydrofolate dehydrogenase 1 0.000
protein S 0.000
TCN2 0.000
SHMT1 0.000
alpha-1A-adrenergic receptor 0.000
Leukocyte immunoglobulin-like receptor A3 0.000
serine hydroxymethyltransferase 0.000
glutathione S-transferase class theta 0.000
protein C 0.000
TYMS 0.000
MTHFS 0.000
formyltetrahydrofolate synthetase 0.000
FTHFD 0.000
Cytosolic serine hydroxymethyltransferase 0.000
plasminogen activator inhibitor-1 0.000
solute carrier family 6 member 4 0.000
plasminogen activator inhibitor 0.000
FOLR1 0.000
solute carrier family 19 member 1 0.000
LCMT1 0.000
CNTNAP4 0.000
RFC 0.000
B-12 0.000
beta-fibrinogen 0.000
formyltetrahydrofolate dehydrogenase 0.000
AGTRAP 0.000
methionine adenosyltransferase II 0.000
coagulation factor V 0.000
Partitioning defective 3-like protein 0.000
glycoprotein IIIa 0.000
dihydropyrimidine dehydrogenase 0.000
betaine-homocysteine methyltransferase 0.000
N-acetyltransferase-1 0.000
BHMT 0.000
betaine homocysteine methyltransferase 0.000
antithrombin 0.000
cytosolic serine hydroxymethyltransferase 0.000
CENP-Q 0.000
APBB1 0.000
Reduced Folate Carrier 0.000
BHMT2 0.000
choline dehydrogenase 0.000
ITGB3 0.000
Reduced folate carrier 0.000
ornithine decarboxylase 1 0.000
KCNIP4 0.000
MMACHC 0.000
Glycine N-methyltransferase 0.000
UBE4B 0.000
FTCD 0.000
leucine carboxyl methyltransferase 0.000
glutathione S-transferase omega 1 0.000
GJA4 0.000
PRICKLE2 0.000
CBS 0.000
phosphatidylethanolamine N-methyltransferase 0.000
GP1BA 0.000
FR-beta 0.000
glucose-6-phosphate 1-dehydrogenase 0.000
cblD 0.000
thiopurine methyltransferase 0.000
FOLR2 0.000
S-adenosylhomocysteine hydrolase 0.000
MAP7 0.000
MAT2A 0.000
calmodulin 1 0.000
CD320 0.000
SHMT 0.000
TNFRSF8 0.000
dihydrofolate reductase 0.000
thymidylate synthetase 0.000
DACT2 0.000
GSTT1 0.000
transcobalamin II 0.000
ERCC4 0.000
type I protein C 0.000
MAGEA1 0.000
hemoglobin beta chain 0.000
LSM2 0.000
transforming growth factor beta receptor II 0.000
apolipoprotein E 0.000
antithrombin III 0.000
MAT2B 0.000
hepatocyte nuclear factor 1 alpha 0.000
GTL2 0.000
fidgetin 0.000
dimethylglycine dehydrogenase 0.000
HOXB3 0.000
dopamine receptor D3 0.000
SAM 0.000
GCP2 0.000
cblF 0.000
PEMT 0.000
PTHR 0.000
LIPC 0.000
damage-regulated autophagy modulator 0.000
FLT3 receptor tyrosine kinase 0.000
RFC) 0.000
carnitine palmitoyltransferase 1A 0.000
MAT1A 0.000
histone-lysine N-methyltransferase 0.000
glutathione-S-transferase M1 0.000
GSTM1 0.000
FilGAP 0.000
ADRA1A 0.000
RASGRP1 0.000
coagulation factor II 0.000
GPR8 0.000
folylpolyglutamate synthetase 0.000
ARMS 0.000
endothelial lipase 0.000
Serine hydroxymethyltransferase 0.000
GSTO1 0.000
NIPA1 0.000
cystathionine gamma-lyase 0.000
LSM1 0.000
catechol-O-methyltransferase 0.000
sarcosine dehydrogenase 0.000
CBFA2T3 0.000
ADRB3 0.000
GART 0.000
10-formyltetrahydrofolate dehydrogenase 0.000
CUBN 0.000
SHMT2 0.000
methyltransferase 0.000
glutamate carboxypeptidase II 0.000
GSTP1 0.000
ITGA2 0.000
DCP1 0.000
Myf-6 0.000
HTR2C 0.000
NaSi-1 0.000
Glycerol kinase 0.000
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Disease
hyperhomocysteinemia 0.016
homocystinuria 0.002
folate deficiency 0.001
Dihydrofolate reductase deficiency 0.000
methionine synthase deficiency 0.000
CBS deficiency 0.000
Thrombophilia 0.000
Factor II mutation 0.000
adult meningioma 0.000
glutamate formiminotransferase deficiency 0.000
Factor V Leiden mutation 0.000
vascular disease 0.000
Mesenteric infarction 0.000
Activated protein C resistance 0.000
Placental infarction 0.000
homocystinemia 0.000
childhood ALL 0.000
vitamin B12 deficiency 0.000
cardiovascular disease 0.000
NFLD 0.000
Left main coronary artery disease 0.000
stroke 0.000
acute lymphoblastic leukemia 0.000
coronary artery disease 0.000
Primary angle-closure glaucoma 0.000
Imerslund 0.000
Bipolar II disorder 0.000
cblF 0.000
deep vein thrombosis 0.000
atherosclerosis 0.000
colorectal cancer 0.000
preeclampsia 0.000
megaloblastic anemia 0.000
Down syndrome 0.000
vitamin B deficiency 0.000
choline deficiency 0.000
cystathioninuria 0.000
colon neoplasm 0.000
Cerebral venous thrombosis 0.000
lupus 0.000
male infertility 0.000
Lymphoblastic lymphoma 0.000
MEST 0.000
Protein S deficiency 0.000
PC deficiency 0.000
riboflavin deficiency 0.000
methylmalonic acidemia 0.000
mesenteric thrombosis 0.000
cancer 0.000
carcinogenesis 0.000
adult ALL 0.000
schizophrenia 0.000
Acute encephalopathy 0.000
Central retinal artery occlusion 0.000
trisomy 2 0.000
Ischemic stroke 0.000
lupus 0.000
childhood NHL 0.000
Retinal vein occlusion 0.000
hypertension 0.000
eclampsia 0.000
abruptio placentae 0.000
Migraine with aura 0.000
migraine 0.000
myocardial infarction 0.000
abortion 0.000
alcohol effect 0.000
pulmonary embolism 0.000
encephalomalacia 0.000
Budd-Chiari syndrome 0.000
Perthes disease 0.000
optic nerve glioma 0.000
PLAT 0.000
unilateral blindness 0.000
favism 0.000
Demented 0.000
systemic lupus erythematosus 0.000
cleft palate 0.000
hypertension in pregnancy 0.000
Acute mesenteric ischemia 0.000
cleft lip/palate 0.000
venous stasis 0.000
lymphoblastoma 0.000
Squamous Cell Carcinoma 0.000
TMN 0.000
idiopathic disorder 0.000
cerebral thrombosis 0.000
Pulmonary thromboembolism 0.000
Diabetic peripheral neuropathy 0.000
pyruvate kinase deficiency 0.000
azoospermia 0.000
FHM 0.000
breast cancer 0.000
renal disease 0.000
developmental delay 0.000
coprophagy 0.000
chromosome disorder 0.000
cerebral infarction 0.000
menstrual migraine 0.000
sickle cell disease 0.000
ischemic optic neuropathy 0.000
CIN II 0.000
coronary heart disease 0.000
cardiovascular risk factor 0.000
Portal vein thrombosis 0.000
thalassemia minor 0.000
diabetic nephropathy 0.000
arteriosclerosis 0.000
FRAXA 0.000
transient ischemic attack 0.000
vitamin B6 deficiency 0.000
Deep vein thrombosis 0.000
stage IV NSCLC 0.000
antiphospholipid syndrome 0.000
arachnodactyly 0.000
hemiplegic migraine 0.000
leukoencephalopathy 0.000
secondary polycythemia 0.000
peripheral vascular disease 0.000
APOA1 0.000
LCP 0.000
gastric cancer 0.000
lymphoma 0.000
oligospermia 0.000
CIN 1 0.000
perforated duodenal ulcer 0.000
colon cancer 0.000
metabolic syndrome 0.000
postmenopausal bone loss 0.000
Chimera 0.000
primary central nervous system lymphoma 0.000
unipolar depression 0.000
habitual abortion 0.000
rheumatoid arthritis 0.000
diabetes 0.000
hypertensive retinopathy 0.000
Meningioma 0.000
Meningioma 0.000
hemiparesis 0.000
dementia 0.000
bipolar disorder 0.000
Hepatotoxicity 0.000
Alzheimer's disease 0.000
CIN I 0.000
essential hypertension 0.000
infertility 0.000
Primary open-angle glaucoma 0.000
cervical intraepithelial neoplasia 0.000
amaurosis 0.000
adenoma 0.000
Vascular dementia 0.000
XPD 0.000
bilateral breast cancer 0.000
osteoporosis 0.000
beta thalassemia 0.000
polycystic ovary syndrome 0.000
complicated pregnancy 0.000
Wolfram syndrome 0.000
Hereditary spastic paraplegia 0.000
RDA 0.000
more...
Symptom
Livedoid 0.000
photopsia 0.000
hand pain 0.000
inanition 0.000
metamorphopsia 0.000
Decreased activity 0.000
headache 0.000
hypotonia 0.000
limb pain 0.000
paraparesis 0.000
overweight 0.000
dysarthria 0.000
hypertonia 0.000
seizures 0.000
photophobia 0.000
spasticity 0.000
ataxia 0.000
spasm 0.000
numbness 0.000
pallor 0.000
tremor 0.000
angina 0.000
abdominal pain 0.000
vomiting 0.000
memory loss 0.000
nausea 0.000
cyanosis 0.000
neck pain 0.000
hemiplegia 0.000
weakness 0.000
cachexia 0.000
lethargy 0.000
fatigue 0.000
hepatomegaly 0.000
paresis 0.000
hemoptysis 0.000
chest pain 0.000
dizziness 0.000
cough 0.000
insomnia 0.000
dyspnea 0.000
pain 0.000
stigma 0.000
anorexia 0.000
hypothermia 0.000
diarrhea 0.000
anesthesia 0.000
Drug
Vitamin B12 0.000
Folic Acid 0.000
Hakka 0.000
THF 0.000
Cobalamin 0.000
Lamisil 0.000
Lamisil 0.000
FAD 0.000
pyridoxal phosphate 0.000
Deoxyadenosine 0.000
Vitamin B 0.000
GVG 0.000
Pyridoxal 0.000
Gemfibrozil 0.000
Fragment 0.000
Pemetrexed 0.000
Leucovorin 0.000
Troglitazone 0.000
NADH 0.000
Riboflavin 0.000
TEL 0.000
Bevacizumab 0.000
Oxaliplatin 0.000
DDAVP 0.000
DDAVP 0.000
Arsenic trioxide 0.000
CTA 0.000
TAC 0.000
Simvastatin 0.000
Amiloride 0.000
Fructose 0.000
Paraffin 0.000
MDS 0.000
CSF 0.000
AZT 0.000
Fluorescein 0.000
AZT 0.000
Fluorescein 0.000
niacin 0.000
Portal 0.000
vitamin E 0.000
Nephron 0.000
CTX 0.000
Nephron 0.000
ICI 0.000
Monit 0.000
CTX 0.000
CTX 0.000
ascorbate 0.000
Indomethacin 0.000
lysine 0.000
Cardiovasc 0.000
PTH 0.000
ENT 0.000
Ethanol 0.000
Asn 0.000
ROS 0.000
Leaf 0.000
IL-2 0.000
Dermatol 0.000
Enzyme
methylenetetrahydrofolate reductase 0.999
methylenetetrahydrofolate reductase 0.991
methionine synthase reductase 0.019
methionine synthase 0.012
methionine synthase 0.012
methylenetetrahydrofolate dehydrogenase 0.004
methylenetetrahydrofolate dehydrogenase 0.003
cystathionine beta-synthase 0.002
homocysteine methyltransferase 0.001
thymidylate synthase 0.001
formyltetrahydrofolate synthetase 0.001
serine hydroxymethyltransferase 0.000
cyclohydrolase 0.000
5,10-methenyltetrahydrofolate synthetase 0.000
APC 0.000
methionine adenosyltransferase 0.000
dihydropyrimidine dehydrogenase 0.000
betaine-homocysteine methyltransferase 0.000
dihydropyrimidine dehydrogenase 0.000
10-formyltetrahydrofolate dehydrogenase 0.000
glutamate formiminotransferase 0.000
choline dehydrogenase 0.000
cystathionine gamma-synthase 0.000
phosphatidylethanolamine N-methyltransferase 0.000
glycine N-methyltransferase 0.000
AICAR transformylase 0.000
thiopurine methyltransferase 0.000
dihydrofolate reductase 0.000
formylmethanofuran dehydrogenase 0.000
homoserine transacetylase 0.000
dimethylglycine dehydrogenase 0.000
caffeoyl-CoA O-methyltransferase 0.000
carboxypeptidase G2 0.000
folylpolyglutamate synthetase 0.000
sarcosine dehydrogenase 0.000
histone-lysine N-methyltransferase 0.000
glycinamide ribonucleotide transformylase 0.000
conjugase 0.000
CSAD 0.000
bleomycin hydrolase 0.000
cystathionine gamma-lyase 0.000
nicotinamide N-methyltransferase 0.000
methionyl-tRNA synthetase 0.000
heterodisulfide reductase 0.000
ACE 0.000
guanidinoacetate methyltransferase 0.000
inosine triphosphatase 0.000
jararhagin 0.000
thymidine phosphorylase 0.000
methyl coenzyme M reductase 0.000
paraoxonase 0.000
AGT 0.000
cysteine dioxygenase 0.000
PRT 0.000
paraoxonase 0.000
LexA repressor 0.000
NQO1 0.000
glutathione S-transferase 0.000
thrombin-activatable fibrinolysis inhibitor 0.000
aldehyde dehydrogenase 0.000
ADH3 0.000
S-adenosyl-L-homocysteine hydrolase 0.000
aldehyde dehydrogenase 0.000
proprotein convertase 0.000
aldehyde dehydrogenase 0.000
aldehyde dehydrogenase 0.000
catechol O-methyltransferase 0.000
aldehyde dehydrogenase 0.000
PTA 0.000
prostate-specific membrane antigen 0.000
choline kinase 0.000
lactonase 0.000
acetate kinase 0.000
cholesterol acyltransferase 0.000
lysyl oxidase 0.000
glycine decarboxylase 0.000
dopamine beta-hydroxylase 0.000
GTP cyclohydrolase I 0.000
asparaginase 0.000
fatty acid desaturase 0.000
tissue plasminogen activator 0.000
glycerol kinase 0.000
aldehyde oxidase 0.000
thrombin 0.000
DNA methyltransferase 0.000
microsomal epoxide hydrolase 0.000
furin 0.000
UDP-glucuronosyltransferase 0.000
S-adenosylmethionine decarboxylase 0.000
delta-aminolevulinic acid dehydratase 0.000
CYP7A1 0.000
formate dehydrogenase 0.000
formate dehydrogenase 0.000
glutathione reductase 0.000
formate dehydrogenase 0.000
CAD 0.000
subtilisin 0.000
CAD 0.000
flavin-containing monooxygenase 0.000
CAD 0.000
lecithin:cholesterol acyltransferase 0.000
protein phosphatase 2A 0.000
phenylalanine hydroxylase 0.000
PGM 0.000
gamma-glutamylcysteine synthetase 0.000
diaphorase 0.000
pyruvate carboxylase 0.000
polo-like kinase 1 0.000
AOR 0.000
tryptophan hydroxylase 0.000
aspartate aminotransferase 0.000
cathepsin D 0.000
TdT 0.000
calcineurin 0.000
glucose-6-phosphate dehydrogenase 0.000
lactase 0.000
chaperonin 0.000
alcohol dehydrogenase 0.000
N-acetyltransferase 0.000
sucrase 0.000
DNA ligase 0.000
DNA ligase 0.000
diaphorase 0.000
endonuclease 0.000
lipase 0.000
ribonucleotide reductase 0.000
glucose-6-phosphatase 0.000
lipoprotein lipase 0.000
aldose reductase 0.000
thromboplastin 0.000
P-glycoprotein 0.000
NADPH-diaphorase 0.000
phosphoenolpyruvate carboxykinase 0.000
phosphoenolpyruvate carboxykinase 0.000
phosphoenolpyruvate carboxykinase 0.000
invertase 0.000
phosphorylase 0.000
renin 0.000
ERK 0.000
kallikrein 0.000
AST 0.000
choline acetyltransferase 0.000
phospholipase A2 0.000
GSK 0.000
NOS 0.000
DNA polymerase 0.000
phosphodiesterase 0.000
creatine kinase 0.000
lipoxygenase 0.000
gamma-glutamyl transpeptidase 0.000
superoxide dismutase 0.000
transcriptase 0.000
lysozyme 0.000
glutathione peroxidase 0.000
ATPase 0.000
urokinase-type plasminogen activator 0.000
monoamine oxidase 0.000
focal adhesion kinase 0.000
alanine aminotransferase 0.000
alkaline phosphatase 0.000
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Compound
homocysteine 0.025
Homocysteine 0.003
Homocysteine 0.003
PGA 0.002
methionine 0.000
CH3-THF 0.000
Menoctone 0.000
adenosylmethionine 0.000
5,10-methenyltetrahydrofolate 0.000
betaine 0.000
S-adenosylhomocysteine 0.000
CBS 0.000
5-formyltetrahydrofolate 0.000
DNA 0.000
dUMP 0.000
Diamant 0.000
Methotrexate 0.000
Thiouracil 0.000
Tetrahydrocurcumin 0.000
Methionine 0.000
5,10-methylene-THF 0.000
Cobalamin 0.000
Benazepril 0.000
valine 0.000
FAD 0.000
folinic acid 0.000
Choline 0.000
10-formyltetrahydrofolate 0.000
TMP 0.000
Deoxyadenosine 0.000
Cystathionine 0.000
Cystathionine 0.000
alanine 0.000
C 10 0.000
C 10 0.000
dihydrofolate 0.000
TCN 0.000
creatinine 0.000
11-dehydro-thromboxane 0.000
Clin 0.000
Bantu 0.000
Pyridoxal 0.000
pentosidine 0.000
Glycine, 0.000
Dec 0.000
TIB 0.000
TDT 0.000
5-FU 0.000
CoM 0.000
Formate 0.000
PDT 0.000
Pyridoxine 0.000
Glycine, 0.000
TBE 0.000
PLP 0.000
dimethylarsinic acid 0.000
dimethylarsinic acid 0.000
dimethylarsinic acid 0.000
dimethylarsinic acid 0.000
dimethylarsinic acid 0.000
norvaline 0.000
NADPH 0.000
NADPH 0.000
norvaline 0.000
Azathioprine 0.000
Sulfasalazine 0.000
Valproic acid 0.000
nicotinic acid 0.000
dimethylarsinic acid 0.000
Acyl-CoA 0.000
Capecitabine 0.000
Valine 0.000
Valproic acid 0.000
MTX 0.000
MMA 0.000
Arsenite 0.000
MMA 0.000
Warfarin 0.000
serine 0.000
EPC 0.000
cysteine 0.000
NADH 0.000
HBB 0.000
Uracil 0.000
MMA 0.000
pteridine 0.000
TEL 0.000
Pac 0.000
Riboflavin 0.000
d4T 0.000
nicotinamide 0.000
SAH 0.000
HCA 0.000
DMA 0.000
DMA 0.000
Evans Blue 0.000
Purine 0.000
Paraquat 0.000
FAP 0.000
FAP 0.000
T 1 0.000
DMA 0.000
Creatine 0.000
Paraquat 0.000
Hemoglobin 0.000
HCB 0.000
Coenzyme Q10 0.000
H2S 0.000
formaldehyde 0.000
NAD 0.000
NADP 0.000
Statin 0.000
NAD 0.000
formaldehyde 0.000
Lignin 0.000
FMN 0.000
Benzene 0.000
Cardiol 0.000
His 0.000
Agarose 0.000
AICAR 0.000
L-threonine 0.000
CPA 0.000
THF 0.000
Phosphatidylcholine 0.000
Heparin 0.000
CPA 0.000
Abbott 0.000
DBP 0.000
hydroxyindoleacetic acid 0.000
CPA 0.000
vitamin D 0.000
dUTP 0.000
MSM 0.000
DBP 0.000
MCP 0.000
nitric oxide 0.000
Fructose 0.000
H2S 0.000
CPA 0.000
uridine 0.000
neopterin 0.000
Genistein 0.000
alcohol dehydrogenase 0.000
prostaglandin F2alpha 0.000
pyrimidine 0.000
pyrimidine 0.000
L-DOPA 0.000
Taurine 0.000
ASC 0.000
T10 0.000
coenzyme Q10 0.000
glutamate 0.000
Parenteral 0.000
glucose 0.000
Cholesterol 0.000
isoleucine 0.000
Ascorbic acid 0.000
isoleucine 0.000
TBI 0.000
more...