Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:1.5.1.3 (dihydrofolate reductase)
5,819 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein dihydrofolate reductase 0.897 DHFR 0.165 thymidylate synthase 0.021 Dihydrofolate reductase 0.012 glycinamide ribonucleotide formyltransferase 0.005 folylpolyglutamate synthetase 0.004 thymidylate synthetase 0.003 DHPS 0.001 MTX 0.001 reduced folate carrier 0.001 NADPH 0.001 folylpoly-gamma-glutamate synthetase 0.001 dihydrofolate reductase-like protein 1 0.001 NADP+ 0.001 sepiapterin reductase 0.000 dihydrofolate reductase-like 1 0.000 MTHFD1 0.000 DHFRP2 0.000 SHMT1 0.000 TAFII-105 0.000 RING3-like protein 0.000 SLC19A1 0.000 purH 0.000 dihydropteridine reductase 0.000 RFC) 0.000 RFC1 0.000 serine hydroxymethyltransferase 0.000 Cholesterol 27-hydroxylase 0.000 Endothelial nitric oxidase synthase 0.000 HLA-SB beta 0.000 HCG1 0.000 SS18L2 0.000 reductase 0.000 TYMS 0.000 methylenetetrahydrofolate dehydrogenase 0.000 MTHFR 0.000 TMP 0.000 dCMP deaminase 0.000 MTR 0.000 beta adaptin 0.000 mutS homolog 3 0.000 MRP-L20 0.000 TRAF interacting protein 0.000 hormone receptor 0.000 OVCA2 0.000 thymidine kinase 0.000 MTHFD2 0.000 NADP 0.000 SSXT 0.000 COPG1 0.000 TGF-beta activated kinase 0.000 MnSOD precursor 0.000 Mol 0.000 serine hydroxymethyltransferase 1 0.000 folate binding protein 0.000 GAR transformylase 0.000 TAFII105 0.000 C12orf35 0.000 ACTR1A 0.000 HIP1 protein 0.000 RING3 protein 0.000 cytoplasmic serine hydroxymethyltransferase 0.000 Sepiapterin reductase 0.000 fused 0.000 MTRR 0.000 COXIV 0.000 60kD 0.000 C1-tetrahydrofolate synthase 0.000 TFDP1 0.000 RPF2 0.000 SQM1 0.000 PHS2 0.000 DNA polymerase alpha 0.000 E2F1 0.000 E2F-1 0.000 NFRKB 0.000 GCH 0.000 RAPGEF6 0.000 RAB1 0.000 ATIC 0.000 more...

Disease malaria 0.000 CEM 0.000 Dihydrofolate reductase deficiency 0.000 R-binder deficiency 0.000 Plasmodium falciparum malaria 0.000 glutamate formiminotransferase deficiency 0.000 leukemia 0.000 methionine synthase deficiency 0.000 folate deficiency 0.000 cancer 0.000 Squamous Cell Cancer 0.000 transcobalamin II deficiency 0.000 ASSA 0.000 DA5 0.000 myelosuppression 0.000 tumor 0.000 Stenotrophomonas maltophilia infection 0.000 Ovary 0.000 AKE 0.000 DHPR deficiency 0.000 lymphoblastic leukemia 0.000 cblF 0.000 mesothelioma 0.000 retinoblastoma 0.000 Ovary 0.000 cryptosporidiosis 0.000 Downbeat nystagmus 0.000 Mycobacterium 0.000 Enzyme inhibition 0.000 PCP 0.000 toxoplasmosis 0.000 Diabetic gastroparesis 0.000 osteosarcoma 0.000 MCF 0.000 xeroderma pigmentosum 0.000 acute lymphoblastic leukemia 0.000 bacterial dysentery 0.000 Shigella sonnei 0.000 Cockayne syndrome 0.000 childhood ALL 0.000 choriocarcinoma 0.000 XPE 0.000 mouse leukemia L1210 0.000 hyperphenylalaninemia 0.000 stage III colorectal cancer 0.000 isosporiasis 0.000 pneumonia 0.000 Leukemia 0.000 Condensation 0.000 breast cancer 0.000 VRSA 0.000 SDS 0.000 tuberculosis 0.000 carcinoma 0.000 DSH 0.000 sarcoma 180 0.000 African trypanosomiasis 0.000 leishmaniasis 0.000 pediatric solid tumor 0.000 Choriocarcinoma 0.000 orotic aciduria 0.000 non-small cell lung cancer 0.000 acute monocytic leukemia 0.000 hepatocellular carcinoma 0.000 megaloblastic anemia 0.000 opportunistic infection 0.000 cytomegalovirus 0.000 LIS1 0.000 AIDS 0.000 solid tumor 0.000 MPS IIIA 0.000 MRSA 0.000 erythroleukemia 0.000 Shaver 0.000 TTP 0.000 herpes simplex 0.000 carcinogenesis 0.000 Chagas 0.000 fibrosarcoma 0.000 SAR 0.000 more...

Symptom inanition 0.000 starvation 0.000 nausea and vomiting 0.000 diarrhea 0.000 general problem 0.000 DNA marker 0.000 muscle rigidity 0.000 collapse 0.000 nausea 0.000 HSA 0.000 vomiting 0.000 dystonia 0.000 erythema 0.000 spasticity 0.000 ataxia 0.000 splenomegaly 0.000 agitation 0.000 exhaustion 0.000 anorexia 0.000 acidity 0.000 weakness 0.000 tremor 0.000 fatigue 0.000 overweight 0.000 dyspnea 0.000 abdominal pain 0.000 seizures 0.000 pain 0.000 headache 0.000 anesthesia 0.000

Drug THF 0.001 Pemetrexed 0.001 Alimta 0.001 Met-Tyr-Gly 0.000 Pemetrexed disodium 0.000 BH4 0.000 Fansidar 0.000 Fansidar 0.000 Tmr 0.000 Pralatrexate 0.000 Asn 0.000 Trimetrexate glucuronate 0.000 Leucovorin 0.000 G418 0.000 7-Methylguanosine 0.000 Methotrexat 0.000 1,2,4-Triazole 0.000 Paraplatin 0.000 Forodesine 0.000 Atovaquone 0.000 Atovaquone 0.000 Compound 18 0.000 Gemzar 0.000 Glide 0.000 Thyrogen 0.000 TMX 0.000 Trimethoprim-sulfamethoxazole 0.000 Toltrazuril 0.000 Orthoclone OKT3 0.000 Bactrim 0.000 Allegra 0.000 Allegra 0.000 Amprolium 0.000 ampicillin 0.000 Folic Acid 0.000 Malarone 0.000 Navelbine 0.000 lysine 0.000 Compound 16 0.000 Isoprinosine 0.000 Compound 15 0.000 Trypanothione 0.000 Doripenem 0.000 DNase I 0.000 Dihydro 0.000 Pertuzumab 0.000 Kenyan 0.000 NADH 0.000 Artesunate 0.000 FSH-beta 0.000 Dithranol 0.000 Trib 0.000 Vinorelbine 0.000 AGG 0.000 ARA-C 0.000 Miltefosine 0.000 Primaquine 0.000 GEO 0.000 Compound 9 0.000 Propidium 0.000 Ketotifen 0.000 Gel 0.000 Arsenic trioxide 0.000 Ergosterol 0.000 Meth 0.000 Mycophenolic acid 0.000 Fragment 0.000 Mutagen 0.000 TRM 0.000 Oxaliplatin 0.000 CTT 0.000 Isoniazid 0.000 ABC 0.000 MEA 0.000 Epigallocatechin 0.000 OMP 0.000 IFN-beta 0.000 Clofibrate 0.000 Lovastatin 0.000 ICI 0.000 more...

Enzyme dihydrofolate reductase 1.000 thymidylate synthase 0.024 dihydropteroate synthase 0.017 folylpolyglutamate synthetase 0.004 PTR1 0.002 glycinamide ribonucleotide transformylase 0.000 sepiapterin reductase 0.000 serine hydroxymethyltransferase 0.000 dihydrofolate synthetase 0.000 formyltransferase, dihydrofolate 0.000 methylenetetrahydrofolate dehydrogenase 0.000 IMP dehydrogenase 0.000 Cpro-2 0.000 glutamate formiminotransferase 0.000 dihydropteridine reductase 0.000 dCMP hydroxymethylase 0.000 AICAR transformylase 0.000 dCMP deaminase 0.000 GTP cyclohydrolase I 0.000 blasticidin-S deaminase 0.000 deoxynucleoside monophosphate kinase 0.000 thymidine kinase 0.000 formyltetrahydrofolate synthetase 0.000 EC 2.7.4.4 0.000 methylenetetrahydrofolate dehydrogenase 0.000 3-N-aminoglycoside acetyltransferase 0.000 dCTPase 0.000 cyclohydrolase 0.000 carboxypeptidase G2 0.000 methionine synthase 0.000 HPPK 0.000 ribonucleotide reductase 0.000 methylenetetrahydrofolate reductase 0.000 5,10-methenyltetrahydrofolate synthetase 0.000 ribonucleotide reductase 0.000 conjugase 0.000 dihydroorotase 0.000 phenylalanyl-tRNA synthetase 0.000 methylenetetrahydrofolate reductase 0.000 methionine synthase 0.000 DNA polymerase 0.000 aromatic amine dehydrogenase 0.000 aspartate transcarbamylase 0.000 dUTPase 0.000 thymidylate kinase 0.000 enoyl-ACP reductase 0.000 D-aminopeptidase 0.000 enoyl-ACP reductase 0.000 adenine phosphoribosyltransferase 0.000 chaperonin 0.000 aminoglycoside adenylyltransferase 0.000 6-pyruvoyltetrahydropterin synthase 0.000 streptomycin adenylyltransferase 0.000 malyl-CoA lyase 0.000 uridine hydrolase 0.000 orotidine-5'-phosphate decarboxylase 0.000 aminoglycoside 6'-N-acetyltransferase 0.000 alpha-1,4-glucan lyase 0.000 adenosine nucleosidase 0.000 L-asparagine synthetase 0.000 RNA polymerase 0.000 amidophosphoribosyltransferase 0.000 methionine synthase reductase 0.000 HIV-1 protease 0.000 chloramphenicol acetyltransferase 0.000 Streptomyces griseus protease B 0.000 phenylalanine hydroxylase 0.000 GAR 0.000 endothiapepsin 0.000 dCTP deaminase 0.000 p-hydroxybenzoate hydroxylase 0.000 kynurenine formamidase 0.000 topoisomerase 0.000 D-amino acid aminotransferase 0.000 rhodanese 0.000 cytidine deaminase 0.000 alpha-lytic protease 0.000 topoisomerase 0.000 dihydropyrimidine dehydrogenase 0.000 dihydroneopterin aldolase 0.000 more...

Compound dihydrofolate 0.038 TMQ 0.006 Methotrexate 0.004 Trimetrexate 0.003 pteridine 0.003 Pyrimethamine 0.001 MTX 0.001 NADPH 0.001 NADPH 0.001 Trimethoprim 0.001 PRPP 0.001 6-(bromomethyl)-2,4-pteridinediamine 0.001 1843U89 0.001 pyrimidine 0.001 BW 301U 0.001 pyrimidine 0.001 Sulfadoxine 0.001 ZD1694 0.000 folinic acid 0.000 5-formyltetrahydrofolate 0.000 NADP 0.000 2,4-diaminopyrido[2,3-d]pyrimidine-6-carbonitrile 0.000 TMP 0.000 Aminopterin 0.000 DNA 0.000 DDMP 0.000 Proguanil 0.000 dUMP 0.000 Dihydropteroate 0.000 Bisbrusatolyl malonate 0.000 Etoprine 0.000 quinazoline 0.000 quinazoline 0.000 10-formyltetrahydrofolate 0.000 PGA 0.000 Tetrahydroneopterin 0.000 C9H10Cl2O2 0.000 4-phenyl-1,2,4-triazolidine-3,5-dione 0.000 Diaveridine 0.000 C8H7N7 0.000 TMP 0.000 TMP 0.000 TMP 0.000 Homofolate 0.000 C8H7N7 0.000 Microlenin 0.000 Sepiapterin 0.000 nicotinamide 0.000 C4H4N2O2 0.000 5-bromotryptophan 0.000 tert-butyl cyanoacetate 0.000 10-formyldihydrofolate 0.000 CH3-THF 0.000 Cirsilineol 0.000 N-methylbenzenesulfonamide 0.000 C20H24O6 0.000 2-Aminopyrimidine 0.000 Chloroquinoxaline sulfonamide 0.000 2-(tert-butylamino)ethanol 0.000 ethyl isocyanatoacetate 0.000 5,10-methylene-THF 0.000 Conformer B 0.000 Baker's Antifol 0.000 2-cyanoacetohydrazide 0.000 5,10-methenyltetrahydrofolate 0.000 4-pyrimidinol 0.000 7H-pyrrolo[3,2-f]quinazoline-1,3-diamine 0.000 cTMP 0.000 DHF 0.000 glutamic acid 0.000 6-Methyluracil 0.000 Tetrahydrobiopterin 0.000 7,8-Dihydrobiopterin 0.000 methyl 4-formylbenzoate 0.000 2-butanone oxime 0.000 2-methylquinoxaline 0.000 NAAAF 0.000 7-Methylguanosine 0.000 6-fluorotryptophan 0.000 2,4-pyrimidinediamine 0.000 more...

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