Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.5.1.3 (dihydrofolate reductase)
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Human Gene/Protein
TAFII-105 12.4
dihydrofolate reductase-like 1 12.4
DHFR 12.4
RING3-like protein 12.4
dihydrofolate reductase 12.4
dihydrofolate reductase-like protein 1 12.1
Endothelial nitric oxidase synthase 11.4
SS18L2 11.4
DHFRP2 11.4
Cholesterol 27-hydroxylase 11.4
HCG1 11.4
HLA-SB beta 11.4
glycinamide ribonucleotide formyltransferase 11.3
Dihydrofolate reductase 11.3
DHPS 10.9
mutS homolog 3 10.8
beta adaptin 10.8
MRP-L20 10.8
TRAF interacting protein 10.8
folylpolyglutamate synthetase 10.5
COPG1 10.4
MnSOD precursor 10.4
TGF-beta activated kinase 10.4
SSXT 10.4
folylpoly-gamma-glutamate synthetase 10.1
thymidylate synthase 10.1
OVCA2 10.1
RING3 protein 10.1
ACTR1A 10.1
HIP1 protein 10.1
TAFII105 10.1
C12orf35 10.1
RPF2 9.8
serine hydroxymethyltransferase 1 9.7
RAPGEF6 9.6
cytoplasmic serine hydroxymethyltransferase 9.6
Cytochrome c oxidase subunit II 9.4
PDXDC1 9.4
SQM1 9.4
TBP associated factor 9.4
solute carrier family 19 member 1 9.4
DYR 9.4
SRRF 9.4
MTHFD1 9.4
PHS2 9.4
thymidylate synthetase 9.4
reduced folate carrier 9.4
SHMT1 9.3
PSMD13 9.2
NADPH oxidase organizer 1 9.2
GADD45 gamma 9.2
L-alanine:glyoxylate aminotransferase 9.2
I-TRAF 9.2
NFRKB 9.2
sepiapterin reductase 9.2
MTHFD2 9.1
dipeptidyl peptidase 9 9.1
C1-tetrahydrofolate synthase 9.1
MAST4 9.1
TFDP1 9.1
Formiminotransferase-cyclodeaminase 9.1
FTCD 9.1
serine hydroxymethyltransferase 2 9.0
Sepiapterin reductase 9.0
FOXJ3 9.0
TSase 9.0
IFN-alpha 5 9.0
SS18L1 9.0
SLC19A1 8.9
RAB1 8.9
60kD 8.8
UFD2 8.8
purH 8.8
SRPR 8.8
FKBP-25 8.8
MTHFS 8.8
delta globin 8.8
SEC13 8.7
ALDH1L2 8.7
ribosomal protein L36 8.7
RFC1 8.7
GAR transformylase 8.7
AICARFT 8.5
CDH8 8.5
HLA-DP beta 8.5
TYMS 8.5
methylenetetrahydrofolate dehydrogenase 8.4
TFDP2 8.4
RING3 8.4
MAN1A1 8.4
HUG1 8.4
dCMP deaminase 8.4
ATIC 8.4
6-pyruvoyltetrahydropterin synthase 8.4
32kD 8.3
TIM44 8.3
HSSB 8.3
PSME2 8.3
ubiquitin-like protein FAT10 8.3
dihydropteridine reductase 8.3
thymidine kinase-1 8.3
methylenetetrahydrofolate dehydrogenase 1 8.3
MTX 8.3
FOLR3 8.2
MXRA5 8.2
folate binding protein 8.2
E2F-5 8.2
F56 8.2
syndecan 2 8.2
NGX6 8.2
HSA5 8.2
IARS 8.2
VPH1 8.2
GABRE 8.1
50kD 8.1
SHMT2 8.1
Serine hydroxymethyltransferase 8.1
TAOK1 8.0
HB3 8.0
Rpn6 8.0
COXIV 8.0
ATPase subunit 9 8.0
serine hydroxymethyltransferase 8.0
CDC14B 8.0
ABCB2 8.0
mitochondrial serine hydroxymethyltransferase 8.0
HPB-MLT 8.0
BAZ2A 7.9
MTX2 7.9
E2F-2 7.9
TAPL 7.8
QM gene 7.8
GCH 7.8
MTR 7.8
adenylosuccinate synthase 7.8
excision repair cross-complementing 1 7.7
methionine adenosyltransferase II 7.7
ABCB9 7.7
TRM1 7.7
DP-2 7.6
delta-globin 7.6
CYB 7.6
IF3(mt) 7.6
UBA6 7.6
FK506-binding protein 12 7.6
MSH3 7.5
platelet-derived growth factor A chain 7.5
I100 7.5
formyltetrahydrofolate synthetase 7.5
ribosomal protein L34 7.5
RFC) 7.5
NADP+ 7.5
MAT2 7.5
Hepassocin 7.5
UFD1 7.5
synaptotagmin II 7.5
CR6-interacting factor 1 7.4
TIEG 7.4
NUB1 7.4
Nanog homeobox 7.4
E2F5 7.4
FOXK1 7.4
FOLR1 7.4
OBR 7.4
NUDT15 7.3
arylamine N-acetyltransferase 1 7.3
HIP1 7.3
H4B 7.3
DCoH 7.3
CCAAT-binding transcription factor 7.3
SHMT 7.3
APCL 7.2
guanine nucleotide releasing factor 7.2
MTRR 7.2
NIM1 7.2
IFN-kappa 7.2
2'-phosphotransferase 7.2
BUB3 7.2
TMP1 7.2
KAP3 7.2
Hexokinase-2 7.1
MTCP1 7.1
AIPL1 7.1
GMP reductase 7.1
cytosolic serine hydroxymethyltransferase 7.1
HOXB3 7.1
SUCLG1 7.1
cdc25B 7.1
COX5A 7.1
PRP16 7.1
ORC4 7.1
FRB 7.0
LAG-1 7.0
pyridoxine 5'-phosphate oxidase 7.0
CDKN3 7.0
COX5B 7.0
cblF 7.0
midline 1 7.0
dUTPase 7.0
MTHFR 7.0
Capsid protein 7.0
CTF1 7.0
T-complex protein 1 7.0
Glutathione synthetase 7.0
PYCR1 7.0
EF-1a 7.0
GFRP 7.0
GCH1 6.9
MutS homolog 6.9
MT-ND2 6.9
FBP2 6.9
MAP17 6.9
ITPase 6.9
CKS2 6.9
GTP cyclohydrolase I 6.9
ACTG2 6.9
UQCRC1 6.9
6-pyruvoyl-tetrahydropterin synthase 6.9
hMSH3 6.9
PRKRA 6.8
APT2 6.8
E2F-1 6.8
TBN 6.8
nucleoporin p62 6.8
MRP7 6.8
GMP synthase 6.8
thymidylate kinase 6.8
BS4 6.8
E2F transcription factor 3 6.8
BCKD kinase 6.7
PRT1 6.7
TMP 6.7
OGC 6.7
SECT 6.7
AK3 6.7
folate-binding protein 6.7
DHPR 6.7
NME2 6.7
FAT10 6.7
TPPP 6.7
GRA 6.7
BHMT 6.7
ubiquitin C 6.6
carboxypeptidase D 6.6
UBE2M 6.6
lamin B2 6.6
homeotic protein 6.6
TCN2 6.6
Thymidine kinase 6.6
methionine synthase 6.6
DRTF1 6.6
RAD6B 6.6
ACTG1 6.6
methionine synthase reductase 6.6
EMP1 6.6
RP-A 6.6
XPE 6.6
GART 6.6
MTTP 6.5
NOB1 6.5
DPP10 6.5
ERCC6 6.5
MDM4 6.5
inosine monophosphate dehydrogenase 6.5
kit-ligand 6.5
FKBP 6.5
E2F4 6.4
cytochrome oxidase subunit II 6.4
DNA polymerase alpha 6.4
cyclin C 6.4
NADPH 6.4
p107 6.4
mannose phosphate isomerase 6.4
K37 6.4
NCK1 6.4
MM46 6.4
preprotein translocase 6.4
TIM22 6.4
E2F8 6.4
myosin IC 6.4
RBL2 6.4
Arylamine N-acetyltransferase 6.4
guanine deaminase 6.4
IMPDH2 6.4
PIK3CB 6.3
RPA1 6.3
dTMP kinase 6.3
EPC1 6.3
Uridine phosphorylase 6.3
UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase 6.3
proton-coupled folate transporter 6.3
Tpr 6.3
LKR 6.3
XRCC6 6.3
cytochrome P4502D6 6.3
CER1 6.2
short chain dehydrogenase/reductase 6.2
RAP30 6.2
geminin 6.2
B-Myb 6.2
inosine triphosphatase 6.2
P1b 6.2
RNA binding motif 6.2
E2F1 6.2
TR-1 6.2
nesprin-1 6.2
TC II 6.2
MYOG 6.2
S100A13 6.2
Orc2 6.2
ADP/ATP carrier protein 6.2
K38 6.2
diubiquitin 6.1
DNA mismatch repair protein 6.1
CTP synthase 6.1
HE1 6.1
UMP synthase 6.1
RPS14 6.1
CTP synthetase 6.1
OPRT 6.1
more...
Disease
Dihydrofolate reductase deficiency 11.4
R-binder deficiency 10.8
glutamate formiminotransferase deficiency 10.1
methionine synthase deficiency 9.4
Squamous Cell Cancer 8.8
ASSA 8.7
transcobalamin II deficiency 8.7
DA5 8.6
Stenotrophomonas maltophilia infection 8.3
AKE 8.2
DHPR deficiency 7.9
cblF 7.6
Downbeat nystagmus 7.4
Diabetic gastroparesis 7.0
CEM 6.8
bacterial dysentery 6.7
Plasmodium falciparum malaria 6.5
XPE 6.5
Enzyme inhibition 6.4
folate deficiency 6.4
stage III colorectal cancer 6.3
mouse leukemia L1210 6.2
Ovary 6.1
isosporiasis 6.0
VRSA 5.9
DSH 5.7
pediatric solid tumor 5.5
orotic aciduria 5.5
hyperphenylalaninemia 5.5
Ovary 5.4
Choriocarcinoma 5.3
malaria 5.3
Shigella sonnei 5.3
Cockayne syndrome 5.2
cryptosporidiosis 5.2
MPS IIIA 5.2
Shaver 5.1
myelosuppression 5.0
lymphoblastic leukemia 5.0
Condensation 4.9
coprophagy 4.8
AT3 4.8
AT3 4.8
AT3 4.8
AT3 4.8
AT3 4.8
ARH 4.8
AT3 4.8
AT3 4.8
AT3 4.8
AT3 4.8
LIS1 4.8
Plasmodium vivax infection 4.8
nagana 4.8
sarcoma 180 4.8
pharyngotonsillitis 4.7
childhood ALL 4.7
xeroderma pigmentosum 4.7
acute monocytic leukemia 4.6
TNS 4.6
Parvovirus B19 infection 4.6
Shigella boydii 4.5
mesothelioma 4.5
familial Alzheimer disease 4.5
megaloblastic anemia 4.4
refractory cancer 4.3
choriocarcinoma 4.3
Tropical Diseases 4.3
Sanfilippo 4.3
PCP 4.3
toxoplasmosis 4.3
HMS 4.3
CMD 4.2
CMD 4.2
riboflavin deficiency 4.2
TTP 4.2
retinoblastoma 4.1
FIM 4.1
African trypanosomiasis 4.1
AIDS-related Kaposi's sarcoma 4.1
NS4 4.0
primary hyperoxaluria 4.0
trophoblastic tumor 4.0
Breast carcinoma 4.0
adenocarcinoma of the colon 4.0
Superinfection 4.0
Shigella dysenteriae 3.9
HEP 3.9
RP4 3.9
Plasmodium falciparum infection 3.9
APOB 3.8
PDR 3.8
Larsen 3.8
EL4 3.8
opportunistic infection 3.8
vitamin B12 deficiency 3.8
leukemia 3.8
Lowe 3.7
melioidosis 3.7
Lymphatic filariasis 3.7
PIT 3.7
primary central nervous system lymphoma 3.7
TTP 3.7
Rous sarcoma 3.7
drug usage 3.6
erythroleukemia 3.6
EVA 3.6
osteosarcoma 3.6
Varicella zoster 3.6
HTS 3.6
MRSA 3.5
CAA 3.5
Leigh syndrome 3.5
T-cell acute lymphoblastic leukemia 3.4
Mesothelioma 3.4
Weil 3.4
multicentric Castleman's disease 3.4
malleus 3.4
CSB 3.4
gastrointestinal disease 3.4
inflammatory joint disease 3.4
CSB 3.4
CNS tumors 3.3
scalded skin syndrome 3.3
trypanosomiasis 3.3
acute sinusitis 3.3
cervical squamous cell carcinoma 3.3
Staphylococcus aureus infection 3.3
Buruli ulcer 3.3
acute lymphoblastic leukemia 3.3
PTR 3.3
MAC 3.2
elephantiasis 3.2
solid tumor 3.2
thymic carcinoma 3.2
ISH 3.2
macrocytic anemia 3.2
PMT 3.2
Leukemia 3.2
MCF 3.2
AAA 3.2
kidney tumor 3.2
juvenile rheumatoid arthritis 3.2
fibrosarcoma 3.1
SAR 3.1
phlebitis 3.1
phenylketonuria 3.1
NSD 3.1
Ovarian Cancer 3.1
leishmaniasis 3.1
CAA 3.1
hyperhomocysteinemia 3.1
Chagas 3.1
Gardner's syndrome 3.1
MPS I 3.0
babesiosis 3.0
leukopenia 3.0
Angiostrongylus cantonensis 3.0
PDB 3.0
carcinosarcoma 3.0
anthrax 3.0
ganglioglioma 3.0
methylmalonic acidemia 3.0
MMA 2.9
histiocytic lymphoma 2.9
EMT 2.9
Wright 2.9
keratoacanthoma 2.9
AMD 2.9
HNSCC 2.9
delirium tremens 2.9
adult ALL 2.9
gliosarcoma 2.9
Kaposi's sarcoma 2.9
HBB 2.9
HBB 2.9
HBB 2.9
Mycobacterium 2.9
bacterial pneumonia 2.9
morphea 2.9
monocytic leukemia 2.9
Adenovirus 2.8
Goldstein 2.8
DIP 2.8
dysplastic nevi 2.8
NLS 2.8
AMN 2.8
filariasis 2.7
laryngeal squamous cell carcinoma 2.7
AAS 2.7
Tag 2.7
Fanconi syndrome 2.7
Age-related macular degeneration 2.7
plasmacytoma 2.7
TCC 2.7
ileitis 2.7
HSP 2.7
avian sarcoma 2.7
hypovitaminosis 2.7
emerging infectious disease 2.7
Mastitis 2.7
abdominal aortic aneurysm 2.7
non-small cell lung cancer 2.7
beta thalassemia 2.6
congenital toxoplasmosis 2.6
Ideas 2.6
Hermansky-Pudlak syndrome 2.6
HCI 2.6
epithelial ovarian cancer 2.6
DDP 2.6
orf 2.6
RGS 2.6
Shigella 2.6
parasitic disease 2.6
hyperoxaluria 2.6
immune deficiency 2.6
epithelioma 2.6
leukodystrophy 2.6
mammary tumor 2.5
homocystinuria 2.5
mental handicap 2.5
nocardiosis 2.5
staphylococcus 2.5
DMS 2.5
transitional cell carcinoma of the bladder 2.5
Shigella flexneri 2.4
Testes 2.4
acute leukemia 2.4
neutropenia 2.4
mycosis fungoides 2.4
PIC 2.4
cytomegalovirus 2.4
GCE 2.4
dysentery 2.3
Osteosarcoma 2.3
Osteosarcoma 2.3
stomatitis 2.3
pneumonia 2.3
LDLR 2.3
metastatic breast cancer 2.3
acute promyelocytic leukemia 2.3
HOS 2.3
herpes simplex 2.3
hereditary spherocytosis 2.3
proliferative diabetic retinopathy 2.3
lung carcinoma 2.3
SDS 2.3
ABL 2.3
leukoencephalopathy 2.2
drug withdrawal 2.2
typhus 2.2
skin ulcers 2.2
colon cancer 2.2
CHS 2.2
anaplastic astrocytoma 2.2
Castleman's disease 2.2
chronic urticaria 2.2
T-cell lymphoma 2.2
diphtheria 2.1
neoplastic transformation 2.1
Appendix 2.1
Appendix 2.1
Appendix 2.1
renal cancer 2.1
gonococcal 2.1
idiopathic dilated cardiomyopathy 2.1
psoriasis 2.1
trichinellosis 2.1
respiratory infection 2.1
DiGeorge syndrome 2.1
spotted fever 2.0
enzyme deficiency 2.0
mole 2.0
rash 2.0
Infections 2.0
gastroparesis 2.0
infectious endocarditis 1.9
tuberculosis 1.9
hemangiopericytoma 1.9
ACP 1.9
Gaucher disease 1.9
MICA 1.9
lysosomal storage disease 1.9
PLS 1.9
Wuchereria 1.9
CTX 1.9
BLM 1.8
monoclonal gammopathy of undetermined significance 1.8
autoimmune thyroid disease 1.8
adenocarcinoma of the lung 1.8
uveal melanoma 1.8
L. infantum 1.8
PCA 1.8
MAS 1.8
Klebsiella 1.8
PGA 1.8
CAP 1.8
head and neck cancer 1.8
scabies 1.8
AIN 1.8
HCG 1.8
otitis 1.8
Wells 1.8
B-ALL 1.8
sarcoma 1.8
hepatocellular carcinoma 1.8
mole 1.7
Delhi 1.7
fits 1.7
lymphosarcoma 1.7
erythroderma 1.7
colibacillosis 1.7
MIP 1.7
squamous cell carcinoma 1.7
oligodendroglioma 1.7
embryonal carcinoma 1.7
fibromatosis 1.7
coccidiosis 1.7
carcinogenesis 1.7
papilloma 1.7
more...
Symptom
inanition 4.6
general problem 2.7
DNA marker 2.6
muscle rigidity 2.3
nausea and vomiting 2.2
starvation 1.7
diarrhea 0.9
HSA 0.9
collapse 0.6
dystonia 0.4
nausea 0.2
vomiting -0.2
spasticity -0.2
erythema -0.3
ataxia -0.5
splenomegaly -0.9
agitation -1.1
exhaustion -1.3
anorexia -1.3
acidity -1.5
tremor -1.8
weakness -1.8
fatigue -2.2
overweight -2.3
dyspnea -2.4
abdominal pain -2.5
seizures -2.9
headache -3.4
pain -3.6
anesthesia -4.3
Drug
Met-Tyr-Gly 12.4
Alimta 10.3
Tmr 10.1
Pemetrexed disodium 9.6
Trimetrexate glucuronate 9.4
Pemetrexed 9.2
Pralatrexate 9.0
7-Methylguanosine 8.8
Methotrexat 8.4
1,2,4-Triazole 8.2
Fansidar 8.1
Fansidar 8.0
Forodesine 7.9
Paraplatin 7.9
THF 7.4
Thyrogen 7.4
Compound 18 7.2
TMX 7.1
Toltrazuril 7.1
BH4 7.1
Leucovorin 7.0
Atovaquone 7.0
Atovaquone 6.9
Gemzar 6.9
Orthoclone OKT3 6.8
Allegra 6.7
Allegra 6.7
Amprolium 6.7
Folic Acid 6.4
Bactrim 6.4
Malarone 6.4
Trimethoprim-sulfamethoxazole 6.2
Glide 6.1
G418 5.9
Navelbine 5.9
Compound 16 5.7
Isoprinosine 5.6
Compound 15 5.5
Trypanothione 5.5
Doripenem 5.4
Pertuzumab 5.4
FSH-beta 5.2
Dithranol 5.1
Asn 5.1
Artesunate 5.0
Dihydro 5.0
Vinorelbine 4.7
Trib 4.6
ARA-C 4.6
Miltefosine 4.5
Primaquine 4.5
Compound 9 4.4
Propidium 4.4
AGG 4.4
Ketotifen 4.2
Ergosterol 4.1
Mycophenolic acid 4.0
TRM 3.9
Kenyan 3.8
GEO 3.8
CTT 3.7
Arsenic trioxide 3.7
MEA 3.6
Epigallocatechin 3.6
Meth 3.6
Oxaliplatin 3.6
OMP 3.5
Isoniazid 3.5
ampicillin 3.5
DNase I 3.3
Clofibrate 3.3
Fragment 3.2
Urokinase 3.1
Lovastatin 3.0
OTC 2.9
PMEA 2.9
Erlotinib 2.9
Campath 2.9
Campath 2.9
IFN-beta 2.9
Riboflavin 2.8
TEL 2.8
TAT 2.8
Rosiglitazone 2.8
Pravastatin 2.8
Mutagen 2.7
BoNT/A 2.7
ETS 2.6
Fluorescein 2.6
Amoxicillin 2.6
NADH 2.6
DEX 2.6
Alanine 2.6
TTC 2.6
Fluorescein 2.5
Cetuximab 2.5
NVP 2.5
GRF 2.5
Omeprazole 2.4
Prednisone 2.4
AraC 2.4
OTC 2.4
Dakar 2.4
ICI 2.3
FLP 2.3
ACT 2.3
ABC 2.3
Gel 2.3
lysine 2.2
Vitamin B 2.1
Angiotensin II 2.1
Nitric Oxide 2.1
Pronase 2.1
Fluconazole 2.1
ZnCl2 2.1
ZnCl2 2.1
NBT 2.0
BLM 2.0
CTX 2.0
CTX 1.9
Gleevec 1.9
Bortezomib 1.9
VCR 1.8
Taxol 1.8
CPR 1.7
CTX 1.7
PTC 1.6
G-CSF 1.6
FAD 1.6
CPT-11 1.5
Itraconazole 1.5
ADR 1.4
Frontal 1.4
-deoxyadenosine 1.4
uPA 1.4
EPI 1.4
DMI 1.4
MDS 1.3
Herceptin 1.3
Glycerol 1.2
Adriamycin 1.2
TMS 1.2
CDP 1.2
NH3 1.2
Imatinib 1.1
pyridoxal phosphate 1.1
IFN-gamma 1.1
HCG 1.0
ETA 1.0
caffeine 0.8
CSF 0.8
lactose 0.7
MRC 0.7
IL-2 0.6
p75 0.5
Biopolymers 0.4
Albumin 0.2
ROS 0.2
MAP 0.1
Glutathione 0.0
CAM -0.1
Leaf -0.4
ROC -0.5
EE2 -0.5
nitroglycerin -0.7
Ethanol -0.8
citric acid -0.9
ascorbate -1.1
Monit -2.7
Dermatol -2.8
Cardiovasc -5.2
Enzyme
formyltransferase, dihydrofolate 12.4
dihydrofolate reductase 12.4
dihydropteroate synthase 11.2
blasticidin-S deaminase 10.8
PTR1 10.7
folylpolyglutamate synthetase 10.5
EC 2.7.4.4 10.4
Cpro-2 10.4
3-N-aminoglycoside acetyltransferase 10.1
deoxynucleoside monophosphate kinase 10.1
thymidylate synthase 10.1
glutamate formiminotransferase 10.0
dihydrofolate synthetase 9.8
glycinamide ribonucleotide transformylase 9.5
dCMP hydroxymethylase 9.5
sepiapterin reductase 9.2
AICAR transformylase 9.2
dCTPase 9.0
HPPK 9.0
5,10-methenyltetrahydrofolate synthetase 8.9
methylenetetrahydrofolate dehydrogenase 8.9
aromatic amine dehydrogenase 8.5
methylenetetrahydrofolate dehydrogenase 8.5
formyltetrahydrofolate synthetase 8.4
dCMP deaminase 8.4
D-aminopeptidase 8.3
aminoglycoside adenylyltransferase 8.2
serine hydroxymethyltransferase 8.2
malyl-CoA lyase 8.1
streptomycin adenylyltransferase 8.1
dihydropteridine reductase 7.9
carboxypeptidase G2 7.9
uridine hydrolase 7.9
6-pyruvoyltetrahydropterin synthase 7.9
alpha-1,4-glucan lyase 7.7
L-asparagine synthetase 7.6
adenosine nucleosidase 7.6
IMP dehydrogenase 7.5
GTP cyclohydrolase I 7.5
aminoglycoside 6'-N-acetyltransferase 7.5
conjugase 7.4
dihydroorotase 7.4
cyclohydrolase 7.4
enoyl-ACP reductase 7.3
enoyl-ACP reductase 7.3
phenylalanyl-tRNA synthetase 7.3
Streptomyces griseus protease B 7.2
dCTP deaminase 7.1
amidophosphoribosyltransferase 7.1
thymidylate kinase 7.1
kynurenine formamidase 7.0
D-amino acid aminotransferase 7.0
endothiapepsin 6.9
dUTPase 6.9
methionine synthase 6.8
dihydroneopterin aldolase 6.8
methionine synthase reductase 6.8
GMP synthase 6.6
GMP reductase 6.6
alpha-lytic protease 6.6
methionine synthase 6.6
orotidine-5'-phosphate decarboxylase 6.6
p-hydroxybenzoate hydroxylase 6.6
CTP synthase 6.5
MetE 6.5
aspartate transcarbamylase 6.5
GAR 6.5
carboxypeptidase D 6.5
adenine phosphoribosyltransferase 6.4
pantothenate synthetase 6.4
Tpt1 6.4
10-formyltetrahydrofolate dehydrogenase 6.3
Dm-dNK 6.2
xanthine phosphoribosyltransferase 6.2
nicotinic acid phosphoribosyltransferase 6.2
hygromycin B phosphotransferase 6.2
p-hydroxybenzoate hydroxylase 6.1
methylenetetrahydrofolate reductase 6.1
glycine N-methyltransferase 6.1
benzoylformate decarboxylase 6.1
bleomycin hydrolase 6.1
chorismate synthase 6.0
homocysteine methyltransferase 6.0
methylenetetrahydrofolate reductase 6.0
plasmepsin II 5.9
ribonucleotide reductase 5.9
ribonucleotide reductase 5.9
STK2 5.9
triose-phosphate isomerase 5.9
dihydroorotate dehydrogenase 5.8
dihydroorotate dehydrogenase 5.8
alpha-isopropylmalate synthase 5.7
uracil phosphoribosyltransferase 5.7
thymidine kinase 5.7
adenylosuccinate synthetase 5.7
rhodanese 5.7
chaperonin 5.7
transcarboxylase 5.6
dihydropyrimidine dehydrogenase 5.6
methylthioadenosine phosphorylase 5.6
guanase 5.6
Escherichia coli exonuclease III 5.5
PRPP synthetase 5.5
cytidine deaminase 5.5
glutamate racemase 5.5
nicotinamide phosphoribosyltransferase 5.5
isoleucyl-tRNA synthetase 5.5
spermidine/spermine N1-acetyltransferase 5.5
cytosine deaminase 5.5
hydroxynitrile lyase 5.5
phenylalanine hydroxylase 5.4
hydroxynitrile lyase 5.4
methylamine dehydrogenase 5.3
endodeoxyribonuclease 5.3
CTD kinase 5.3
HIV-1 protease 5.3
endonuclease V 5.2
UMP kinase 5.2
aldehyde oxidase 5.2
thymidine phosphorylase 5.2
prostasin 5.2
GMP synthetase 5.2
hydroxynitrile lyase 5.2
uridine phosphorylase 5.2
dihydropyrimidine dehydrogenase 5.1
carbamoylphosphate synthetase 5.1
inosine triphosphatase 5.1
alanine racemase 5.1
phosphoglycerate dehydrogenase 5.1
nucleoside diphosphokinase 5.1
deoxyribonuclease 5.1
asparagine synthetase 5.0
pyroglutamate aminopeptidase 5.0
trypanothione reductase 4.9
chondroitin ABC lyase 4.9
glutamyl-tRNA synthetase 4.9
thiopurine methyltransferase 4.9
mannitol dehydrogenase 4.9
adenylosuccinate lyase 4.9
phosphatidylserine synthase 4.8
catechol O-methyltransferase 4.8
hypoxanthine-guanine phosphoribosyltransferase 4.8
N-acetylglucosaminyltransferase I 4.8
xanthine dehydrogenase 4.7
uridyltransferase 4.7
chloramphenicol acetyltransferase 4.6
glutamic dehydrogenase 4.6
haloalkane dehalogenase 4.6
glutathione synthetase 4.6
CO dehydrogenase 4.6
inositol 3-kinase 4.6
glutaminyl-tRNA synthetase 4.6
AP lyase 4.5
sphingomyelin synthase 4.5
DNA polymerase 4.5
Thy1 4.5
carboxypeptidase A 4.5
peptide deformylase 4.5
farnesyltransferase 4.4
CPS 4.4
farnesyltransferase 4.4
carbonyl reductase 4.4
glutamate synthase 4.4
lysyl-tRNA synthetase 4.3
citrate lyase 4.3
firefly luciferase 4.3
purine nucleoside phosphorylase 4.3
penicillin acylase 4.2
protein farnesyltransferase 4.1
galactokinase 4.1
cysteine synthase 4.1
EPSP synthase 4.1
protochlorophyllide oxidoreductase 4.1
penicillin binding protein 4.1
tryptophanyl-tRNA synthetase 4.1
levansucrase 4.0
spermidine synthase 4.0
Fpg protein 4.0
topoisomerase 4.0
Omi/HtrA2 4.0
methionine adenosyltransferase 4.0
ornithine transcarbamylase 4.0
adenosine deaminase 4.0
deoxycytidine kinase 4.0
micrococcal nuclease 4.0
topoisomerase 4.0
phosphomannose isomerase 3.9
glycolate oxidase 3.9
6-phosphogluconate dehydrogenase 3.9
6-phosphogluconate dehydrogenase 3.9
guanylate kinase 3.9
transpeptidase 3.9
S1 nuclease 3.9
adenosine deaminase 3.9
alpha-L-iduronidase 3.9
squalene epoxidase 3.9
thermolysin 3.9
glutamate synthase 3.8
methionyl-tRNA synthetase 3.8
phytoene synthase 3.8
cathepsin C 3.8
glutamate synthase 3.8
adenylate kinase 3.8
PMT 3.8
xylose isomerase 3.8
methylmalonyl-CoA mutase 3.8
GLO 3.8
arylsulfatase 3.8
choline oxidase 3.7
glutamine synthetase 3.7
halogenase 3.7
cruzipain 3.7
aldehyde dehydrogenase 3.7
PTR 3.7
prostate-specific membrane antigen 3.6
proteinase K 3.6
MPP 3.5
chymosin 3.5
HMG-CoA synthase 3.5
cystathionine beta-synthase 3.5
ornithine decarboxylase 3.5
cdc2 3.5
cytochrome oxidase 3.5
thioredoxin reductase 3.5
lysyl endopeptidase 3.5
aldehyde reductase 3.4
aldehyde reductase 3.4
RNA polymerase 3.4
aldehyde reductase 3.4
P-glycoprotein 3.4
arginine decarboxylase 3.4
aromatic L-amino acid decarboxylase 3.3
aldehyde dehydrogenase 3.3
3-hydroxy-3-methylglutaryl-CoA reductase 3.3
isopeptidase 3.3
PI-PLC 3.3
CDH 3.3
ATP synthase 3.2
adrenodoxin reductase 3.2
MTD 3.2
endonuclease 3.2
beta-lactamase 3.2
RNase T1 3.2
alcohol dehydrogenase 3.1
arginine decarboxylase 3.1
fumarate reductase 3.1
CAD 3.1
aldehyde dehydrogenase 3.1
aldehyde dehydrogenase 3.1
MDR 3.1
CAD 3.1
aldehyde dehydrogenase 3.1
PRE 3.1
CAD 3.1
NOS 3.0
beta-galactosidase 3.0
tryptophan synthase 3.0
polynucleotide kinase 3.0
RNA ligase 3.0
LPL 3.0
AMP deaminase 3.0
cytochrome c peroxidase 3.0
NADH dehydrogenase 2.9
gamma-glutamylcysteine synthetase 2.9
phosphoglycerate kinase 2.9
glyceraldehyde-3-phosphate dehydrogenase 2.9
glyceraldehyde-3-phosphate dehydrogenase 2.9
glucocerebrosidase 2.9
glycerol kinase 2.9
insulin-degrading enzyme 2.9
RNase 2.9
RNase 2.9
PNGase F 2.8
deoxyribonuclease 2.8
malate dehydrogenase 2.8
sialyltransferase 2.8
lactic acid dehydrogenase 2.8
ClpP 2.8
AGT 2.8
sialyltransferase 2.8
sialyltransferase 2.8
N-acetyltransferase 2.8
peptidyl-prolyl cis-trans isomerase 2.8
glyceraldehyde-3-phosphate dehydrogenase 2.8
CFI 2.8
TMT 2.8
TAT 2.8
furin 2.8
sulfatase 2.8
ricin 2.8
GABA transaminase 2.8
aldose reductase 2.7
deaminase 2.7
PHD 2.7
arginine deiminase 2.7
SPC 2.7
aconitase 2.6
FFT 2.6
hexokinase 2.6
KAT 2.6
glycerol-3-phosphate dehydrogenase 2.6
peroxiredoxin 2.6
S-adenosylmethionine decarboxylase 2.6
ALDH 2.6
glycerol-3-phosphate dehydrogenase 2.6
chymotrypsin 2.6
RNase H 2.6
glyceraldehyde-3-phosphate dehydrogenase 2.6
glyceraldehyde-3-phosphate dehydrogenase 2.5
acyl-CoA oxidase 2.5
formate dehydrogenase 2.5
formate dehydrogenase 2.5
BAL 2.5
isocitrate lyase 2.5
RNase III 2.4
glucose dehydrogenase 2.4
angiotensin-converting enzyme 2 2.4
tissue plasminogen activator 2.4
DOPA decarboxylase 2.4
CPR 2.4
more...
Compound
2,4-diaminopyrido[2,3-d]pyrimidine-6-carbonitrile 12.4
Etoprine 12.4
Bisbrusatolyl malonate 12.4
6-(bromomethyl)-2,4-pteridinediamine 12.0
BW 301U 11.5
4-phenyl-1,2,4-triazolidine-3,5-dione 11.4
C8H7N7 11.4
C9H10Cl2O2 11.4
Tetrahydroneopterin 11.4
dihydrofolate 11.4
Trimetrexate 11.2
TMQ 11.2
C8H7N7 10.8
Homofolate 10.8
Microlenin 10.8
1843U89 10.8
Diaveridine 10.6
5-bromotryptophan 10.4
C4H4N2O2 10.4
tert-butyl cyanoacetate 10.4
2-Aminopyrimidine 10.1
C20H24O6 10.1
Chloroquinoxaline sulfonamide 10.1
Cirsilineol 10.1
N-methylbenzenesulfonamide 10.1
2-(tert-butylamino)ethanol 10.1
ethyl isocyanatoacetate 10.1
Aminopterin 10.0
Sulfadoxine 10.0
Conformer B 9.8
10-formyldihydrofolate 9.8
Baker's Antifol 9.8
Dihydropteroate 9.7
Pyrimethamine 9.7
PRPP 9.7
Proguanil 9.7
pteridine 9.6
2-cyanoacetohydrazide 9.6
DDMP 9.6
4-pyrimidinol 9.4
7H-pyrrolo[3,2-f]quinazoline-1,3-diamine 9.4
cTMP 9.4
6-Methyluracil 9.2
ZD1694 9.1
Trimethoprim 9.1
7,8-Dihydrobiopterin 9.0
methyl 4-formylbenzoate 9.0
Sepiapterin 9.0
2-methylquinoxaline 8.8
2-butanone oxime 8.8
7-Methylguanosine 8.8
NAAAF 8.8
5,10-methylene-THF 8.7
2,4-Diamino-6-hydroxypyrimidine 8.7
2,4-pyrimidinediamine 8.7
5-formyltetrahydrofolate 8.6
10-formyltetrahydrofolate 8.5
Methotrexate 8.5
6-pyruvoyltetrahydropterin 8.4
1,2,3-trimethoxybenzene 8.4
ethyl trifluoroacetate 8.4
ethyl trifluoroacetate 8.4
MTX 8.3
Diaminopyridine 8.2
6-Azauridine 8.2
2-Acetylpyridine 8.2
6-fluorotryptophan 8.2
4-methyleneglutamic acid 8.2
1-naphthalenesulfonic acid 8.0
1-naphthalenesulfonic acid 8.0
CH3-THF 8.0
dUMP 8.0
(aminooxy)acetic acid 8.0
1-benzothiophene 8.0
6R-BH4 8.0
5,10-methenyltetrahydrofolate 7.9
7H-pyrrolo[2,3-d]pyrimidine 7.9
Biopterin 7.9
1,3-dichloroacetone 7.7
folinic acid 7.7
1,3-dichloroacetone 7.7
Liriodenine 7.7
dichloropalladium 7.7
1,3,5-triazine-2,4-diamine 7.7
Isethionate 7.6
4,6-dichloropyrimidine 7.6
Acetylshikonin 7.6
Tetrahydrobiopterin 7.3
Sulfathiazole 7.2
tert-butyl carbamate 7.2
Sulfamylon 7.2
TMP 7.2
DHF 7.2
quinazoline 7.2
quinazoline 7.2
aminoacetic acid 7.1
aminoacetic acid 7.1
aminoacetic acid 7.1
M1A 7.1
Cyromazine 7.1
aminoacetic acid 7.0
Mezerein 6.9
aminoacetic acid 6.9
TMP 6.8
9,10-dihydroacridine 6.8
TMP 6.8
TMP 6.8
H4MPT 6.7
GAR 6.7
Methionine sulfoximine 6.6
dUDP 6.5
DMDP 6.5
trifluoroacetaldehyde 6.5
NADPH 6.4
NADPH 6.4
N6-Methyladenosine 6.4
2,6-dichloroisonicotinic acid 6.4
Sulfamethoxazole 6.4
Pterin 6.4
Diflubenzuron 6.4
PGA 6.3
NADP 6.3
FUDR 6.2
pyrimidine 6.2
pyrimidine 6.2
Cucurbitacin B 6.2
alpha-Amanitin 6.2
Distamycin A 6.2
Deoxyribose 6.2
MTA 6.1
FK520 6.1
Thymidine 6.1
Sulfonamide 6.0
PALA 6.0
L-2,4-diaminobutyric acid 5.9
Trifluorothymidine 5.9
Cyanogen bromide 5.9
FCB 5.9
Hypoxanthine 5.8
Leucovorin 5.8
6-Mercaptopurine 5.8
BAF 5.7
3-Deazaneplanocin 5.7
FUR 5.7
TLA 5.7
Polybrene 5.6
carbamyl phosphate 5.6
Puromycin 5.6
TTP 5.6
ACPC 5.6
5-methyltryptophan 5.5
Aphidicolin 5.5
Aphidicolin 5.5
2,4-pentanedione 5.5
2,4-pentanedione 5.5
ASK 5.5
2,4-pentanedione 5.5
2,4-pentanedione 5.5
2,4-pentanedione 5.5
2,4-pentanedione 5.5
bis(2-chloroethyl) 5.5
HN3 5.5
2,4-pentanedione 5.4
2,4-pentanedione 5.4
2,4-pentanedione 5.4
2,4-pentanedione 5.4
Pentamidine 5.4
2,4-pentanedione 5.4
2,4-pentanedione 5.4
2,4-pentanedione 5.4
Piperidine 5.4
2,4-pentanedione 5.4
PYR 5.4
1,3,5-triazine 5.4
butyl nitrite 5.4
Gambogic acid 5.4
1,3,5-triazine 5.4
HN2 5.3
dCTP 5.3
AICAR 5.3
Phosphonate 5.3
Benzothiazole 5.3
4-NQO 5.2
ML-236B 5.2
benzenesulfonyl fluoride 5.2
phthalazine 5.2
nicotinamide 5.2
ethanesulfonic acid 5.1
ethanesulfonic acid 5.1
4-pentenoic acid 5.1
DMPE 5.1
ESE 5.1
Dithranol 5.1
Buthionine sulfoximine 5.1
3GC 5.1
DAM 5.0
EDAP 5.0
Dihydroxyacetone 5.0
TTA 5.0
Valine 5.0
HBr 4.9
N-hydroxysuccinimide ester 4.9
APH 4.9
UMP 4.9
Sanguinarine 4.9
5-oxoproline 4.9
pentanedioic acid 4.9
Purine 4.8
5-oxoproline 4.8
Sparfloxacin 4.8
PABA 4.8
2-butanone 4.8
2-butanone 4.8
2,4-pentanedione 4.7
Arsenite 4.7
Oridonin 4.7
DAM 4.7
dCMP 4.7
Mithramycin 4.7
dATP 4.7
Magnolol 4.7
glutamic acid 4.7
5-oxoproline 4.7
Selenomethionine 4.7
ornithine 4.6
ornithine 4.6
ornithine 4.6
ornithine 4.6
ornithine 4.6
Sulfasalazine 4.6
3-aminobenzamide 4.6
pentanoic acid 4.5
pentanoic acid 4.5
Primaquine 4.5
BUdR 4.5
TDP 4.5
SDA 4.5
Artemisinin 4.5
Azan 4.4
BaCl2 4.4
Novobiocin 4.4
THF 4.4
Chloroquine 4.4
DMS 4.4
Chloroquine 4.4
5-oxoproline 4.3
Methionine 4.3
Ethambutol 4.3
pyridazine 4.3
MnO4 4.3
pyridazine 4.3
2-naphthyl 4.3
1H-1,2,4-triazole 4.3
Hydroxyurea 4.2
HMS 4.2
NMN 4.2
Trp-P-2 4.2
NaAsO2 4.2
Cefuroxime 4.2
PH2 4.2
2-butanone 4.2
pentanoic acid 4.2
NPR 4.2
Psoralen 4.2
IDC 4.1
guanidine 4.1
indoline 4.1
Ile 4.1
Ergosterol 4.1
Ergosterol 4.1
Leflunomide 4.1
Cholic acid 4.1
3-(dimethylamino)propyl 4.1
ORO 4.0
Phorbol 12-myristate 13-acetate 4.0
PDH 4.0
HSO 4.0
Vinca 4.0
pyrazine 4.0
1H-benzimidazole 4.0
dGTP 4.0
trifluoromethanesulfonic acid 4.0
Streptomycin 4.0
DDQ 4.0
Epigallocatechin gallate 3.9
M 2 3.9
HEP 3.9
VPM 3.9
butyryl-CoA 3.9
trifluoromethanesulfonic acid 3.9
Thymine 3.9
TFC 3.9
Guo 3.9
Uracil 3.9
DLT 3.9
AICAR 3.9
PDB 3.9
DAP 3.9
CTP 3.9
Amide 3.8
PAE 3.8
homocysteine 3.8
MIC 3.8
PhIP 3.8
7-methylguanosine 3.8
CNA 3.8
Actinomycin D 3.8
PMT 3.8
d4T 3.8
2-vinylpyridine 3.8
2-vinylpyridine 3.8
2-vinylpyridine 3.8
PHE 3.7
Gemcitabine 3.7
PTR 3.7
cyanamide 3.7
D-gluconate 3.7
Ornithine 3.7
ribose-5-phosphate 3.7
benzenesulfonamide 3.7
more...