Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.5.1.3 (
dihydrofolate reductase
)
5,819
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We have used
SOM
and grid 3D and 4D QSAR schemes for modeling the activity of a series of
dihydrofolate reductase
inhibitors. Careful analysis of the performance and external predictivities proves that this method can provide an efficient inhibition model.
...
PMID:Self-organizing neural networks for modeling robust 3D and 4D QSAR: application to dihydrofolate reductase inhibitors. 1800 9
