Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.5.1.3 (
dihydrofolate reductase
)
5,819
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The tissue distribution of
BAF
was compared by intravenous and subcutaneous injections in rats bearing Walker 256 carcinoma. Following a single dose (6 mg/kg containing 30 microCi 4,6-di-14C-
BAF
), the drug concentrations were determined by radiochemical and
dihydrofolate reductase
assays. The two methods gave comparable results. No metabolites were found by paper chromatographic separations.
...
PMID:Comparative distribution of Baker's antifolate (NSC 139105) in rat tissues after subcutaneous and intravenous injections. 696 27
