Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:1.5.1.20 (methylenetetrahydrofolate reductase)
2,134 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein methylenetetrahydrofolate reductase 2013 5,10-methylenetetrahydrofolate reductase 299 MTHFR 233 prothrombin 193 Mol 172 B12 165 factor V Leiden 162 Sep 152 methionine synthase 150 methionine synthase reductase 94 factor V 87 MTRR 83 thymidylate synthase 82 MTR 71 cystathionine beta-synthase 63 protein C 63 protein S 56 plasminogen activator inhibitor-1 53 reduced folate carrier 45 plasminogen activator inhibitor 40 fibrinogen 33 methylenetetrahydrofolate dehydrogenase 33 antithrombin 33 reductase 30 methyltransferase 28 apolipoprotein E 27 dihydrofolate reductase 26 Methylenetetrahydrofolate reductase 25 antithrombin III 23 CBS 23 insulin 21 Polymerase 20 C-reactive protein 18 dihydropyrimidine dehydrogenase 17 She 17 serine hydroxymethyltransferase 17 factor VIII 17 glutathione S-transferase 17 SAM 17 UTR 17 more...

Disease hyperhomocysteinemia 328 cancer 234 stroke 163 cardiovascular disease 126 atherosclerosis 92 vascular disease 92 coronary artery disease 85 hypertension 83 colorectal cancer 75 tumor 69 breast cancer 59 folate deficiency 59 acute lymphoblastic leukemia 59 diabetes 58 carcinogenesis 56 homocystinuria 55 schizophrenia 53 myocardial infarction 48 deep vein thrombosis 39 preeclampsia 38 Down syndrome 35 Alzheimer's disease 35 systemic lupus erythematosus 34 abortion 32 lupus 31 lymphoma 31 renal disease 30 lupus 30 obesity 27 childhood ALL 27 rheumatoid arthritis 25 dementia 25 migraine 24 gastric cancer 22 pulmonary embolism 22 leukemia 21 Thrombophilia 20 coronary heart disease 20 osteoporosis 19 colon cancer 19 more...

Symptom headache 18 seizures 16 overweight 10 pain 8 fatigue 5 abdominal pain 5 hypotonia 5 ataxia 5 weakness 5 vomiting 5 nausea 4 angina 4 tremor 4 spasticity 3 paraparesis 3 spasm 3 dysarthria 3 chest pain 2 numbness 2 dyspnea 2 cough 2 metamorphopsia 1 hemoptysis 1 anesthesia 1 hand pain 1 hypothermia 1 limb pain 1 photophobia 1 insomnia 1 cyanosis 1 hepatomegaly 1 anorexia 1 hypertonia 1 diarrhea 1 photopsia 1 dizziness 1 memory loss 1 inanition 1 Decreased activity 1 hemiplegia 1 more...

Drug THF 31 FAD 15 Vitamin B12 15 NADH 12 Cardiovasc 10 pyridoxal phosphate 9 CSF 6 Vitamin B 5 lysine 5 Monit 4 Fragment 4 vitamin E 3 Cobalamin 3 ascorbate 3 Nephron 3 Dermatol 2 CTX 2 Bevacizumab 2 Hakka 2 Nephron 2 Folic Acid 2 CTX 1 CTA 1 DDAVP 1 Gemfibrozil 1 MDS 1 Asn 1 CTX 1 Indomethacin 1 GVG 1 DDAVP 1 Fluorescein 1 Ethanol 1 Arsenic trioxide 1 Lamisil 1 IL-2 1 AZT 1 Oxaliplatin 1 Portal 1 Fluorescein 1 more...

Enzyme methylenetetrahydrofolate reductase 2134 methylenetetrahydrofolate reductase 2116 methionine synthase 155 methionine synthase 147 methionine synthase reductase 89 thymidylate synthase 83 APC 80 cystathionine beta-synthase 63 methylenetetrahydrofolate dehydrogenase 33 dihydrofolate reductase 27 methylenetetrahydrofolate dehydrogenase 26 ACE 22 serine hydroxymethyltransferase 19 glutathione S-transferase 18 homocysteine methyltransferase 18 dihydropyrimidine dehydrogenase 17 cyclohydrolase 17 methionine adenosyltransferase 16 dihydropyrimidine dehydrogenase 15 formyltetrahydrofolate synthetase 13 thrombin 12 NQO1 9 thiopurine methyltransferase 8 aldehyde dehydrogenase 8 aldehyde dehydrogenase 7 tissue plasminogen activator 7 ERK 7 aldehyde dehydrogenase 7 aldehyde dehydrogenase 7 aldehyde dehydrogenase 7 betaine-homocysteine methyltransferase 6 cystathionine gamma-synthase 6 aspartate aminotransferase 6 glutathione reductase 5 paraoxonase 5 phosphatidylethanolamine N-methyltransferase 5 calcineurin 5 paraoxonase 5 thymidine phosphorylase 4 MetE 4 more...

Compound homocysteine 785 DNA 340 methionine 251 Dec 168 Clin 161 PGA 127 Homocysteine 83 Homocysteine 83 adenosylmethionine 74 betaine 47 alanine 45 creatinine 37 valine 28 Cardiol 25 S-adenosylhomocysteine 23 CBS 23 water 21 glucose 21 serine 20 cysteine 20 Methotrexate 20 oxygen 18 His 16 FAD 16 NADPH 15 NADPH 15 nitric oxide 13 CH3-THF 13 Pac 12 NADH 12 calcium 12 sodium 11 acetate 11 phosphate 11 Methionine 10 TMP 10 glutamate 10 5,10-methenyltetrahydrofolate 10 5-FU 8 folinic acid 8 more...

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