Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.5.1.19 (
NOS
)
7,285
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
nitric oxide synthase
1779
inducible nitric oxide synthase
1139
neuronal nitric oxide synthase
757
eNOS
545
Sep
485
endothelial nitric oxide synthase
453
Mol
440
lipopolysaccharide
428
cytokine
260
NADPH
213
LPS
211
TNF
190
guanylate cyclase
187
superoxide dismutase
184
calmodulin
181
tumor necrosis factor
159
TGF-beta
151
cyclooxygenase
140
ATP
139
insulin
137
constitutive nitric oxide synthase
135
SOD
133
COX-2
129
IL-6
126
interferon-gamma
124
soluble guanylyl cyclase
120
A-I
119
catalase
116
TNF-alpha
111
ROS
102
caspase-3
96
IFN-gamma
91
GSH
90
NOS2
90
vascular endothelial growth factor
89
COX
87
angiotensin II
83
cyclooxygenase-2
82
NOS3
81
NMDA receptor
79
PKG
77
bradykinin
76
reductase
75
vascular endothelium
75
p38
74
MAPK
72
endothelin-1
72
SNAP
71
guanylyl cyclase
69
diaphorase
69
myeloperoxidase
69
PI3K
64
phosphodiesterase
64
collagen
64
heme oxygenase-1
63
hemoglobin
62
lactate dehydrogenase
61
p53
60
inducible form
60
NOS1
59
gut
58
interferon
57
DAF
56
ERK1
56
fused
55
ATPase
54
Bcl-2
54
substance P
53
IFN
52
glial fibrillary acidic protein
52
Ang II
51
ADP
51
tyrosine hydroxylase
51
VEGF
51
ERK
49
IL-10
49
caveolin-1
47
estrogen receptor
46
PKC
45
COX-1
45
more...
Disease
NAME
1042
tumor
354
ischemia
300
cancer
292
hypertension
252
diabetes
184
PDD
137
lymphoma
132
autism
131
atherosclerosis
128
Peripheral T-cell lymphoma
124
T-cell lymphoma
119
sepsis
118
carcinoma
115
sepsis
114
stroke
106
depression
104
GSH
90
Autism
87
breast cancer
85
Alzheimer's disease
82
cardiovascular disease
79
cerebral ischemia
71
adenocarcinoma
65
heart failure
61
B-cell lymphoma
57
erectile dysfunction
55
myocardial ischemia
54
pulmonary hypertension
52
Hodgkin's disease
51
T-cell lymphomas
50
Asperger syndrome
47
Parkinson's disease
46
hyperglycemia
42
myocardial infarction
42
anaplastic large cell lymphoma
39
obesity
38
metastases
38
Epstein
37
cirrhosis
37
vascular disease
37
leukemia
36
asthma
36
angioimmunoblastic T-cell lymphoma
35
colitis
34
tumor growth
34
ductal carcinoma
33
carcinogenesis
32
type 2 diabetes
32
psychosis
30
renal disease
30
Endothelial dysfunction
30
Disorder
30
inflammatory bowel disease
29
idiopathic dilated cardiomyopathy
28
schizophrenia
28
hepatocellular carcinoma
27
epilepsy
27
major depressive disorder
27
proteinuria
27
bipolar disorder
26
glioma
26
cognitive impairment
25
hypercholesterolemia
25
neuroblastoma
25
PDE
24
tumor progression
24
uterus
23
plaque
23
squamous cell carcinoma
23
sarcoma
23
DLBCL
22
cold
22
Diffuse large B-cell lymphoma
22
acute myeloid leukemia
22
malaria
21
mental illness
21
Duchenne muscular dystrophy
21
portal hypertension
21
anxiety disorders
20
more...
Symptom
pain
82
seizures
52
anesthesia
34
fatigue
17
hyperoxia
17
functional recovery
16
diarrhea
13
headache
12
hypothermia
11
hypercapnia
10
constipation
8
starvation
8
splenomegaly
8
overweight
7
spasm
7
memory loss
6
acute stress
6
anorexia
6
analgesia
5
exhaustion
5
ataxia
5
tremor
5
masculinization
4
respiratory distress
4
dyspnea
4
erythema
4
weakness
4
collapse
4
abdominal pain
4
polyuria
3
thinning
3
HSA
3
angina
3
incoordination
2
vertigo
2
syncope
2
Macula
2
discomfort
2
cachexia
2
chest pain
2
nausea
2
hoarseness
2
hepatomegaly
2
night sweats
2
flushing
2
discomfort
2
skin damage
1
dizziness
1
hyperemesis gravidarum
1
nipple discharge
1
dystonia
1
meningism
1
rundown
1
pallor
1
paresthesia
1
hyperesthesia
1
catatonia
1
Psychiatric symptoms
1
Lower urinary tract symptoms
1
cerebellar ataxia
1
Neuropathic pain
1
orofacial pain
1
Deafferentation
1
neurological disability
1
myalgia
1
hypotonia
1
spasticity
1
ENT
1
tinnitus
1
polydipsia
1
vomiting
1
abdominal discomfort
1
nasal congestion
1
bitter taste
1
back pain
1
agitation
1
apathy
1
numbness
1
nipple discharge
1
chronic constipation
1
more...
Drug
Nitric Oxide
160
ROS
102
lysine
93
IFN-gamma
91
BH4
79
Cardiovasc
66
Aminoguanidine
37
MAP
34
Indomethacin
26
nitroglycerin
26
Angiotensin II
24
FAD
22
NADH
20
Sodium nitroprusside
20
ascorbate
19
Dermatol
18
7-Nitroindazole
18
ICI
18
IL-2
16
CSF
14
caffeine
14
MRC
12
Ethanol
12
vitamin E
12
Spectrum
10
Heme
9
CTX
9
Spectrum
9
G418
8
EE2
8
Gel
7
ETA
7
Methylene blue
7
Forskolin
7
Simvastatin
6
Leaf
6
Fluorescein
5
Ouabain
5
CaCl2
5
CaCl2
5
CTX
5
CaCl2
5
IFN-beta
5
p75
5
Asn
4
Atropine
4
EDR
4
CIA
4
G-CSF
4
citric acid
4
CTX
4
Paraffin
4
Nephron
4
Photofrin
4
Nebivolol
4
TAK
3
DNase I
3
Rosuvastatin
3
Ginseng
3
Sesamol
3
TTC
3
Cilostazol
3
Asthma
3
MDS
3
Galactose
3
Fructose
3
CAM
3
Glutathione
3
ADM
3
Monit
3
TAC
3
Estrogens
3
THF
3
ROC
3
Tacrolimus
2
Frontal
2
NBT
2
Sulfaphenazole
2
Tannic acid
2
Lubeluzole
2
more...
Enzyme
NOS
7285
NO synthase
1113
superoxide dismutase
287
guanylate cyclase
257
NADPH-diaphorase
211
protein kinase
194
mitogen-activated protein kinase
190
catalase
146
ERK
143
NADPH oxidase
116
protein kinase C
103
NADPH oxidase
100
arginase
100
peroxidase
98
diaphorase
80
PKG
77
caspase-3
77
NQO1
72
diaphorase
70
lactate dehydrogenase
67
phosphodiesterase
64
ATPase
57
tyrosine hydroxylase
50
xanthine oxidase
50
focal adhesion kinase
48
phosphatidylinositol 3-kinase
44
reverse transcriptase
43
renin
43
luciferase
41
heme oxygenase
40
glutathione peroxidase
39
AMP-activated protein kinase
38
alanine aminotransferase
31
MAP
29
AMPK
29
aspartate aminotransferase
28
MEK
28
GTP cyclohydrolase I
27
alkaline phosphatase
27
ACE
26
calcineurin
26
thrombin
25
beta-glucuronidase
24
PDE
24
creatine kinase
23
glutathione S-transferase
23
acetylcholinesterase
22
dimethylarginine dimethylaminohydrolase
22
AMPK
22
PARP
21
beta-galactosidase
21
choline acetyltransferase
21
monoamine oxidase
20
nitrate reductase
19
CaMKII
19
nitrate reductase
18
nitrate reductase
18
nitrate reductase
18
nitrate reductase
18
nitrate reductase
18
cytochrome oxidase
16
CD10
16
collagenase
16
adenylate cyclase
16
proteasome
16
phosphoinositide 3-kinase
16
glyceraldehyde-3-phosphate dehydrogenase
16
trypsin
16
complex I
15
RNase
14
RNase
14
phospholipase C
14
lysozyme
13
AST
13
chloramphenicol acetyltransferase
13
caspase-8
12
phospholipase A2
12
argininosuccinate synthetase
12
succinate dehydrogenase
12
argininosuccinate lyase
11
more...
Compound
nitric oxide
3151
arginine
1839
oxygen
586
Dec
544
cGMP
497
calcium
462
DNA
360
sodium
329
nitrate
251
water
224
NADPH
213
NADPH
213
Clin
212
glucose
200
TNF
190
hydrogen
170
nitrogen
156
ATP
139
phosphate
115
glutamate
114
lysine
107
CIT
103
cAMP
98
GSH
92
GSH
92
tyrosine
90
salt
88
NMDA
87
COX
87
nicotinamide
78
DSM
77
cysteine
74
ACh
74
Neuronal
73
acetate
71
GMP
69
ethanol
65
serine
65
potassium
64
Cardiol
63
iron
61
CO2
60
NO3
59
MDA
58
ornithine
57
ornithine
57
ornithine
57
ornithine
57
urea
57
ornithine
57
zinc
56
ADP
56
H2O2
55
prostacyclin
53
ADP
52
ADP
51
PGE2
49
PGE
46
threonine
45
sulfate
43
diacetate
41
noradrenaline
38
creatinine
36
AMP
36
Angiotensin II
35
5-HT
34
Nitro-L-arginine
34
GABA
34
FMN
34
Nitrite
33
GABA
33
Nitrite
33
CAT
31
CAT
31
Ang II
31
benzene
31
CAT
31
pyrrolidine
30
leucine
30
MAP
30
more...