Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.5.1.19 (NOS)
7,285 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
nitric oxide synthase 1779
inducible nitric oxide synthase 1139
neuronal nitric oxide synthase 757
eNOS 545
Sep 485
endothelial nitric oxide synthase 453
Mol 440
lipopolysaccharide 428
cytokine 260
NADPH 213
LPS 211
TNF 190
guanylate cyclase 187
superoxide dismutase 184
calmodulin 181
tumor necrosis factor 159
TGF-beta 151
cyclooxygenase 140
ATP 139
insulin 137
constitutive nitric oxide synthase 135
SOD 133
COX-2 129
IL-6 126
interferon-gamma 124
soluble guanylyl cyclase 120
A-I 119
catalase 116
TNF-alpha 111
ROS 102
caspase-3 96
IFN-gamma 91
GSH 90
NOS2 90
vascular endothelial growth factor 89
COX 87
angiotensin II 83
cyclooxygenase-2 82
NOS3 81
NMDA receptor 79
PKG 77
bradykinin 76
reductase 75
vascular endothelium 75
p38 74
MAPK 72
endothelin-1 72
SNAP 71
guanylyl cyclase 69
diaphorase 69
myeloperoxidase 69
PI3K 64
phosphodiesterase 64
collagen 64
heme oxygenase-1 63
hemoglobin 62
lactate dehydrogenase 61
p53 60
inducible form 60
NOS1 59
gut 58
interferon 57
DAF 56
ERK1 56
fused 55
ATPase 54
Bcl-2 54
substance P 53
IFN 52
glial fibrillary acidic protein 52
Ang II 51
ADP 51
tyrosine hydroxylase 51
VEGF 51
ERK 49
IL-10 49
caveolin-1 47
estrogen receptor 46
PKC 45
COX-1 45
more...
Disease
NAME 1042
tumor 354
ischemia 300
cancer 292
hypertension 252
diabetes 184
PDD 137
lymphoma 132
autism 131
atherosclerosis 128
Peripheral T-cell lymphoma 124
T-cell lymphoma 119
sepsis 118
carcinoma 115
sepsis 114
stroke 106
depression 104
GSH 90
Autism 87
breast cancer 85
Alzheimer's disease 82
cardiovascular disease 79
cerebral ischemia 71
adenocarcinoma 65
heart failure 61
B-cell lymphoma 57
erectile dysfunction 55
myocardial ischemia 54
pulmonary hypertension 52
Hodgkin's disease 51
T-cell lymphomas 50
Asperger syndrome 47
Parkinson's disease 46
hyperglycemia 42
myocardial infarction 42
anaplastic large cell lymphoma 39
obesity 38
metastases 38
Epstein 37
cirrhosis 37
vascular disease 37
leukemia 36
asthma 36
angioimmunoblastic T-cell lymphoma 35
colitis 34
tumor growth 34
ductal carcinoma 33
carcinogenesis 32
type 2 diabetes 32
psychosis 30
renal disease 30
Endothelial dysfunction 30
Disorder 30
inflammatory bowel disease 29
idiopathic dilated cardiomyopathy 28
schizophrenia 28
hepatocellular carcinoma 27
epilepsy 27
major depressive disorder 27
proteinuria 27
bipolar disorder 26
glioma 26
cognitive impairment 25
hypercholesterolemia 25
neuroblastoma 25
PDE 24
tumor progression 24
uterus 23
plaque 23
squamous cell carcinoma 23
sarcoma 23
DLBCL 22
cold 22
Diffuse large B-cell lymphoma 22
acute myeloid leukemia 22
malaria 21
mental illness 21
Duchenne muscular dystrophy 21
portal hypertension 21
anxiety disorders 20
more...
Symptom
pain 82
seizures 52
anesthesia 34
fatigue 17
hyperoxia 17
functional recovery 16
diarrhea 13
headache 12
hypothermia 11
hypercapnia 10
constipation 8
starvation 8
splenomegaly 8
overweight 7
spasm 7
memory loss 6
acute stress 6
anorexia 6
analgesia 5
exhaustion 5
ataxia 5
tremor 5
masculinization 4
respiratory distress 4
dyspnea 4
erythema 4
weakness 4
collapse 4
abdominal pain 4
polyuria 3
thinning 3
HSA 3
angina 3
incoordination 2
vertigo 2
syncope 2
Macula 2
discomfort 2
cachexia 2
chest pain 2
nausea 2
hoarseness 2
hepatomegaly 2
night sweats 2
flushing 2
discomfort 2
skin damage 1
dizziness 1
hyperemesis gravidarum 1
nipple discharge 1
dystonia 1
meningism 1
rundown 1
pallor 1
paresthesia 1
hyperesthesia 1
catatonia 1
Psychiatric symptoms 1
Lower urinary tract symptoms 1
cerebellar ataxia 1
Neuropathic pain 1
orofacial pain 1
Deafferentation 1
neurological disability 1
myalgia 1
hypotonia 1
spasticity 1
ENT 1
tinnitus 1
polydipsia 1
vomiting 1
abdominal discomfort 1
nasal congestion 1
bitter taste 1
back pain 1
agitation 1
apathy 1
numbness 1
nipple discharge 1
chronic constipation 1
more...
Drug
Nitric Oxide 160
ROS 102
lysine 93
IFN-gamma 91
BH4 79
Cardiovasc 66
Aminoguanidine 37
MAP 34
Indomethacin 26
nitroglycerin 26
Angiotensin II 24
FAD 22
NADH 20
Sodium nitroprusside 20
ascorbate 19
Dermatol 18
7-Nitroindazole 18
ICI 18
IL-2 16
CSF 14
caffeine 14
MRC 12
Ethanol 12
vitamin E 12
Spectrum 10
Heme 9
CTX 9
Spectrum 9
G418 8
EE2 8
Gel 7
ETA 7
Methylene blue 7
Forskolin 7
Simvastatin 6
Leaf 6
Fluorescein 5
Ouabain 5
CaCl2 5
CaCl2 5
CTX 5
CaCl2 5
IFN-beta 5
p75 5
Asn 4
Atropine 4
EDR 4
CIA 4
G-CSF 4
citric acid 4
CTX 4
Paraffin 4
Nephron 4
Photofrin 4
Nebivolol 4
TAK 3
DNase I 3
Rosuvastatin 3
Ginseng 3
Sesamol 3
TTC 3
Cilostazol 3
Asthma 3
MDS 3
Galactose 3
Fructose 3
CAM 3
Glutathione 3
ADM 3
Monit 3
TAC 3
Estrogens 3
THF 3
ROC 3
Tacrolimus 2
Frontal 2
NBT 2
Sulfaphenazole 2
Tannic acid 2
Lubeluzole 2
more...
Enzyme
NOS 7285
NO synthase 1113
superoxide dismutase 287
guanylate cyclase 257
NADPH-diaphorase 211
protein kinase 194
mitogen-activated protein kinase 190
catalase 146
ERK 143
NADPH oxidase 116
protein kinase C 103
NADPH oxidase 100
arginase 100
peroxidase 98
diaphorase 80
PKG 77
caspase-3 77
NQO1 72
diaphorase 70
lactate dehydrogenase 67
phosphodiesterase 64
ATPase 57
tyrosine hydroxylase 50
xanthine oxidase 50
focal adhesion kinase 48
phosphatidylinositol 3-kinase 44
reverse transcriptase 43
renin 43
luciferase 41
heme oxygenase 40
glutathione peroxidase 39
AMP-activated protein kinase 38
alanine aminotransferase 31
MAP 29
AMPK 29
aspartate aminotransferase 28
MEK 28
GTP cyclohydrolase I 27
alkaline phosphatase 27
ACE 26
calcineurin 26
thrombin 25
beta-glucuronidase 24
PDE 24
creatine kinase 23
glutathione S-transferase 23
acetylcholinesterase 22
dimethylarginine dimethylaminohydrolase 22
AMPK 22
PARP 21
beta-galactosidase 21
choline acetyltransferase 21
monoamine oxidase 20
nitrate reductase 19
CaMKII 19
nitrate reductase 18
nitrate reductase 18
nitrate reductase 18
nitrate reductase 18
nitrate reductase 18
cytochrome oxidase 16
CD10 16
collagenase 16
adenylate cyclase 16
proteasome 16
phosphoinositide 3-kinase 16
glyceraldehyde-3-phosphate dehydrogenase 16
trypsin 16
complex I 15
RNase 14
RNase 14
phospholipase C 14
lysozyme 13
AST 13
chloramphenicol acetyltransferase 13
caspase-8 12
phospholipase A2 12
argininosuccinate synthetase 12
succinate dehydrogenase 12
argininosuccinate lyase 11
more...
Compound
nitric oxide 3151
arginine 1839
oxygen 586
Dec 544
cGMP 497
calcium 462
DNA 360
sodium 329
nitrate 251
water 224
NADPH 213
NADPH 213
Clin 212
glucose 200
TNF 190
hydrogen 170
nitrogen 156
ATP 139
phosphate 115
glutamate 114
lysine 107
CIT 103
cAMP 98
GSH 92
GSH 92
tyrosine 90
salt 88
NMDA 87
COX 87
nicotinamide 78
DSM 77
cysteine 74
ACh 74
Neuronal 73
acetate 71
GMP 69
ethanol 65
serine 65
potassium 64
Cardiol 63
iron 61
CO2 60
NO3 59
MDA 58
ornithine 57
ornithine 57
ornithine 57
ornithine 57
urea 57
ornithine 57
zinc 56
ADP 56
H2O2 55
prostacyclin 53
ADP 52
ADP 51
PGE2 49
PGE 46
threonine 45
sulfate 43
diacetate 41
noradrenaline 38
creatinine 36
AMP 36
Angiotensin II 35
5-HT 34
Nitro-L-arginine 34
GABA 34
FMN 34
Nitrite 33
GABA 33
Nitrite 33
CAT 31
CAT 31
Ang II 31
benzene 31
CAT 31
pyrrolidine 30
leucine 30
MAP 30
more...