Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.5.1.19 (
NOS
)
7,285
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
nitric oxide synthase
1779
inducible nitric oxide synthase
1139
neuronal nitric oxide synthase
757
eNOS
545
Sep
485
endothelial nitric oxide synthase
453
Mol
440
lipopolysaccharide
428
cytokine
260
NADPH
213
LPS
211
TNF
190
guanylate cyclase
187
superoxide dismutase
184
calmodulin
181
tumor necrosis factor
159
TGF-beta
151
cyclooxygenase
140
ATP
139
insulin
137
constitutive nitric oxide synthase
135
SOD
133
COX-2
129
IL-6
126
interferon-gamma
124
soluble guanylyl cyclase
120
A-I
119
catalase
116
TNF-alpha
111
ROS
102
caspase-3
96
IFN-gamma
91
NOS2
90
GSH
90
vascular endothelial growth factor
89
COX
87
angiotensin II
83
cyclooxygenase-2
82
NOS3
81
NMDA receptor
79
more...
Disease
NAME
1042
tumor
354
ischemia
300
cancer
292
hypertension
252
diabetes
184
PDD
137
lymphoma
132
autism
131
atherosclerosis
128
Peripheral T-cell lymphoma
124
T-cell lymphoma
119
sepsis
118
carcinoma
115
sepsis
114
stroke
106
depression
104
GSH
90
Autism
87
breast cancer
85
Alzheimer's disease
82
cardiovascular disease
79
cerebral ischemia
71
adenocarcinoma
65
heart failure
61
B-cell lymphoma
57
erectile dysfunction
55
myocardial ischemia
54
pulmonary hypertension
52
Hodgkin's disease
51
T-cell lymphomas
50
Asperger syndrome
47
Parkinson's disease
46
myocardial infarction
42
hyperglycemia
42
anaplastic large cell lymphoma
39
obesity
38
metastases
38
vascular disease
37
Epstein
37
more...
Symptom
pain
82
seizures
52
anesthesia
34
fatigue
17
hyperoxia
17
functional recovery
16
diarrhea
13
headache
12
hypothermia
11
hypercapnia
10
constipation
8
starvation
8
splenomegaly
8
spasm
7
overweight
7
acute stress
6
memory loss
6
anorexia
6
analgesia
5
exhaustion
5
ataxia
5
tremor
5
erythema
4
masculinization
4
weakness
4
dyspnea
4
respiratory distress
4
collapse
4
abdominal pain
4
angina
3
thinning
3
polyuria
3
HSA
3
Macula
2
vertigo
2
incoordination
2
cachexia
2
night sweats
2
nausea
2
syncope
2
more...
Drug
Nitric Oxide
160
ROS
102
lysine
93
IFN-gamma
91
BH4
79
Cardiovasc
66
Aminoguanidine
37
MAP
34
Indomethacin
26
nitroglycerin
26
Angiotensin II
24
FAD
22
Sodium nitroprusside
20
NADH
20
ascorbate
19
7-Nitroindazole
18
ICI
18
Dermatol
18
IL-2
16
CSF
14
caffeine
14
vitamin E
12
MRC
12
Ethanol
12
Spectrum
10
Heme
9
Spectrum
9
CTX
9
G418
8
EE2
8
ETA
7
Forskolin
7
Gel
7
Methylene blue
7
Simvastatin
6
Leaf
6
CaCl2
5
CaCl2
5
Ouabain
5
Fluorescein
5
more...
Enzyme
NOS
7285
NO synthase
1113
superoxide dismutase
287
guanylate cyclase
257
NADPH-diaphorase
211
protein kinase
194
mitogen-activated protein kinase
190
catalase
146
ERK
143
NADPH oxidase
116
protein kinase C
103
NADPH oxidase
100
arginase
100
peroxidase
98
diaphorase
80
PKG
77
caspase-3
77
NQO1
72
diaphorase
70
lactate dehydrogenase
67
phosphodiesterase
64
ATPase
57
xanthine oxidase
50
tyrosine hydroxylase
50
focal adhesion kinase
48
phosphatidylinositol 3-kinase
44
renin
43
reverse transcriptase
43
luciferase
41
heme oxygenase
40
glutathione peroxidase
39
AMP-activated protein kinase
38
alanine aminotransferase
31
MAP
29
AMPK
29
MEK
28
aspartate aminotransferase
28
GTP cyclohydrolase I
27
alkaline phosphatase
27
ACE
26
more...
Compound
nitric oxide
3151
arginine
1839
oxygen
586
Dec
544
cGMP
497
calcium
462
DNA
360
sodium
329
nitrate
251
water
224
NADPH
213
NADPH
213
Clin
212
glucose
200
TNF
190
hydrogen
170
nitrogen
156
ATP
139
phosphate
115
glutamate
114
lysine
107
CIT
103
cAMP
98
GSH
92
GSH
92
tyrosine
90
salt
88
NMDA
87
COX
87
nicotinamide
78
DSM
77
cysteine
74
ACh
74
Neuronal
73
acetate
71
GMP
69
ethanol
65
serine
65
potassium
64
Cardiol
63
more...