Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.4.3.13 (lysyl oxidase)
 1,248 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
lysyl oxidase 1246
collagen 615
elastin 310
Sep 97
Mol 97
tropoelastin 73
fibronectin 54
LOX 45
LOXL2 44
type I collagen 41
amine oxidase 40
fibrillin 32
LOXL1 30
ras 29
matrix metalloproteinase 28
Elastin 26
LOXL4 24
superoxide dismutase 24
connective tissue growth factor 22
MMP-2 22
polypeptide 21
vascular endothelial growth factor 20
LOXL3 20
cytokine 19
ceruloplasmin 18
lysyl hydroxylase 18
metalloproteinase 17
diamine oxidase 17
vascular adhesion protein-1 16
MMP-9 16
fibulin-4 16
TLD 16
lysyl oxidase-like 1 15
TGF-beta 15
collagenase 14
COL1A1 14
bone morphogenetic protein 14
LOXL 14
Dance 14
alkaline phosphatase 13
ERK1 13
IL-6 13
angiotensin II 13
E-cadherin 13
prolyl 4-hydroxylase 13
proteoglycan 13
ECM 12
ATP7A 12
PI3K 12
lysyl oxidase-like 2 12
cytochrome c oxidase 11
MMP-1 11
extracellular matrix protein 11
smooth muscle actin 11
metallothionein 11
VEGF 11
TNF 11
alanyl 11
SMA 10
transforming growth factor-beta 10
focal adhesion kinase 10
endoplasmic reticulum 10
ATPase 10
serum albumin 10
FAK 10
tyrosinase 10
glycoprotein 9
chemokine 9
insulin 9
AKT 9
cage 9
transglutaminase 9
periostin 9
decorin 9
cyclin D1 9
ERK 9
Rho 8
vimentin 8
extracellular signal-regulated kinase 8
tissue transglutaminase 8
EPA 8
p38 8
MAPK 8
X-linked 8
precursor protein 8
thrombospondin 7
Smad3 7
epidermal growth factor receptor 7
estrogen receptor 7
tenascin-C 7
tumor necrosis factor 7
LH1 7
cytokine receptor 7
PDGF 7
ELS 7
TNF-alpha 7
osteogenic 6
aggrecan 6
p21 6
platelet-derived growth factor 6
catenin 6
NMR 6
IL-8 6
HIF-1 6
catalase 6
MMP2 6
GTPase 6
GM-CSF 6
c-Jun 6
CTGF 6
gut 5
BMP1 5
SDS 5
X-linked recessive 5
insulin-like growth factor 5
Ang II 5
lysyl oxidase-like protein 5
protein-lysine 6-oxidase 5
COL1A2 5
transglutaminase 2 5
cyclooxygenase-2 5
caspase-3 5
BMP4 5
COL3A1 5
neu 5
matrix protein 5
XFS 5
peroxidase 5
MAO-A 5
JNK 5
fibrillin-2 4
endothelial nitric oxide synthase 4
interacting protein 4
MAO-B 4
osteopontin 4
MNK 4
syndecan 4
H-ras 4
interleukin-6 4
tissue inhibitor of metalloproteinases 4
histone 4
IGF-1 4
ATP 4
endothelin-1 4
chymotrypsin 4
c-Ha-ras 4
tenascin C 4
laminin 5 4
proteasome 4
MMP 4
glucose transporter 4
lysyl oxidase-like 3 4
CD44 4
BMP2 4
biglycan 4
MMP-12 4
TIMP1 4
adhesion molecule 4
MC1 4
AP-1 4
more...
Disease
tumor 156
cancer 149
breast cancer 63
tumor progression 49
metastases 35
diabetes 31
hypertension 27
atherosclerosis 26
heart failure 22
Menkes 22
liver fibrosis 18
emphysema 18
tumor growth 18
tumorigenesis 17
carcinoma 16
pulmonary fibrosis 15
hepatocellular carcinoma 14
osteoporosis 14
squamous cell carcinoma 13
prostate cancer 13
cutis laxa 13
colorectal cancer 12
glaucoma 11
MCF 11
idiopathic pulmonary fibrosis 11
primary tumor 11
myocardial infarction 11
carcinogenesis 10
cirrhosis 10
obesity 10
cornea 10
lung cancer 10
adenocarcinoma 10
abdominal aortic aneurysm 10
Ehlers-Danlos syndrome 9
metastatic breast cancer 9
aggressiveness 9
plaque 9
connective tissue disease 8
Copper deficiency 8
prolapse 8
melanoma 8
aortic aneurysm 7
keratoconus 7
gastric cancer 7
cardiovascular disease 7
osteogenesis imperfecta 7
glioma 7
stroke 6
Marfan syndrome 6
vagina 6
chronic obstructive pulmonary disease 6
Brown 6
liver disease 6
liver cancer 5
bone metastases 5
hyperhomocysteinemia 5
ovarian cancer 5
cardiomyopathy 5
vascular disease 5
Alzheimer's disease 5
pulmonary hypertension 5
myocardial ischemia 5
SDS 5
renal cell carcinoma 4
bone disease 4
rheumatoid arthritis 4
osteoarthritis 4
cleft palate 4
metabolic syndrome 4
renal disease 4
arteriosclerosis 4
heart disease 4
neuropathy 4
solid tumor 4
XFS 4
glioblastoma 4
colon cancer 4
non-small cell lung cancer 4
Thoracic 4
polycystic ovary syndrome 4
hypercholesterolemia 3
type 2 diabetes 3
scleroderma 3
chronic liver disease 3
cataract 3
diabetic retinopathy 3
lung disease 3
EDA 3
myelofibrosis 3
lung carcinoma 3
ventricular hypertrophy 3
liver cancer 3
hyperglycemia 3
chronic active hepatitis 3
tumor angiogenesis 3
brain tumor 3
lung metastases 3
glioblastoma multiforme 3
neuroblastoma 3
intraocular pressure 3
bronchopulmonary dysplasia 3
tumor initiation 3
uterus 3
Oral submucous fibrosis 3
depression 3
PSS 3
hernia 3
oral cancer 3
rectal cancer 3
pancreatic cancer 3
osteosarcoma 3
hepatitis 2
homocystinuria 2
cystic fibrosis 2
chronic hepatitis 2
B-cell lymphoma 2
papillary thyroid cancer 2
ash 2
FAS 2
endocarditis 2
developmental delay 2
Ehlers-Danlos syndrome type IX 2
osteochondrosis 2
esophageal cancer 2
chorioamnionitis 2
muscular atrophy 2
scoliosis 2
thrombocytosis 2
multiple myeloma 2
asthma 2
aggression 2
SEM 2
EDS VI 2
HCC 2
APC 2
Ehlers-Danlos syndrome type VII 2
mitral regurgitation 2
osteoporotic fracture 2
mitral valve prolapse 2
head and neck cancer 2
anemia 2
Dupuytren 2
mole 2
periodontitis 2
iron deficiency 2
schistosomiasis 2
ductal carcinoma 2
Plaque 2
viral hepatitis 2
varices 2
suicide 2
Down syndrome 2
Placenta 2
bladder cancer 2
Anterior 2
mole 2
schizophrenia 2
chronic persistent hepatitis 2
rhabdomyosarcoma 2
more...
Symptom
thinning 6
starvation 4
respiratory distress 3
anesthesia 3
regurgitation 3
seizures 2
acidity 2
diarrhea 2
Stiffness 2
hyperoxia 2
pain 1
back pain 1
hoarseness 1
anorexia 1
halitosis 1
Blotchy 1
hypercapnia 1
emaciation 1
spasm 1
weakness 1
functional recovery 1
fasciculation 1
Drug
lysine 134
Dermatol 19
ascorbate 7
CSF 6
Cardiovasc 6
pyridoxal phosphate 4
Asn 4
IFN-gamma 2
Areca 2
Nephron 2
Gel 2
ABC 2
Doxycycline 1
Botox 1
Pyridoxal 1
Glutathione 1
vitamin E 1
Forskolin 1
Reserpine 1
CCL 1
Etoposide 1
Angiotensin II 1
Fraction 1
Triptorelin 1
CTX 1
EPA 1
Gleevec 1
CoCl2 1
CTX 1
Imatinib 1
Trapidil 1
PTC 1
Aprotinin 1
Gly-Tyr-Gly 1
niacin 1
Isoniazid 1
Torasemide 1
PTH 1
Vitamin K 1
Monensin 1
DHT 1
CTX 1
HCH 1
ROS 1
Orphan 1
Dilantin 1
Sulprostone 1
DHT 1
EE2 1
Axokine 1
Gelfoam 1
Heme 1
Benzylamine 1
Adriamycin 1
Pilocarpine 1
Nephron 1
Phenytoin 1
Vitamin B 1
CoCl2 1
Enzyme
lysyl oxidase 1248
diamine oxidase 60
monoamine oxidase 48
prolyl hydroxylase 40
collagenase 36
mitogen-activated protein kinase 31
superoxide dismutase 26
ceruloplasmin 25
focal adhesion kinase 25
elastase 19
lysyl hydroxylase 18
ERK 18
transglutaminase 16
alkaline phosphatase 13
trypsin 10
tyrosinase 10
ATPase 10
luciferase 9
protein kinase 8
procollagen C-proteinase 7
pepsin 7
reverse transcriptase 6
catalase 6
peroxidase 6
NADPH oxidase 5
NADPH oxidase 5
MMP 4
MEK 4
MMP-3 4
chymotrypsin 4
proteasome 4
carbonic anhydrase 3
methylamine dehydrogenase 3
type III procollagen 3
RNA polymerase 3
lactate dehydrogenase 3
cytochrome oxidase 3
galactose oxidase 3
cathepsin D 3
phosphoinositide 3-kinase 3
aspartate aminotransferase 3
caspase-3 3
transcriptase 3
ACS 3
alanine aminotransferase 3
AMP-activated protein kinase 2
methylenetetrahydrofolate reductase 2
aldehyde dehydrogenase 2
aldehyde dehydrogenase 2
aldehyde dehydrogenase 2
glucose oxidase 2
paraoxonase 2
aldehyde dehydrogenase 2
aldose reductase 2
AMPK 2
topoisomerase 2
aldehyde dehydrogenase 2
hyaluronidase 2
complex I 2
topoisomerase 2
CD10 2
renin 2
chondroitinase 2
phospholipase A2 2
meprin 2
paraoxonase 2
astacin 2
matrix metalloproteinase 2 2
lipoxygenase 2
CCS 2
cathepsin G 2
gamma-glutamylcysteine synthetase 2
laccase 2
dopamine beta-hydroxylase 2
phosphatidylinositol 3-kinase 2
methylenetetrahydrofolate reductase 2
chondroitinase 2
DNA methyltransferase 2
AMPK 2
sulfhydryl oxidase 1
saccharopine dehydrogenase 1
glutathione peroxidase 1
lysozyme 1
hormone-sensitive lipase 1
neutrophil elastase 1
CD13 1
gamma-glutamyl transpeptidase 1
alpha-amylase 1
adenylate cyclase 1
dihydrofolate reductase 1
PRA 1
cathepsin B 1
interstitial collagenase 1
Protein 2 1
cathepsin L 1
polyamine oxidase 1
demethylase 1
isocitrate dehydrogenase 1
acetolactate synthase 1
phenylalanine hydroxylase 1
acid phosphatase 1
thrombin 1
galactosylhydroxylysyl glucosyltransferase 1
diaphorase 1
Omi/HtrA2 1
cystathionine beta-synthase 1
5alpha-reductase 1
NADH dehydrogenase 1
aconitase 1
5alpha-reductase 1
APC 1
plasmin 1
tyrosine hydroxylase 1
PAM 1
isocitrate dehydrogenase 1
ribonuclease 1
urokinase-type plasminogen activator 1
furin 1
endonuclease 1
PKG 1
phosphodiesterase 1
RNase 1
lipoprotein lipase 1
granzyme B 1
TdT 1
methionine synthase 1
apyrase 1
protein kinase C 1
hatching enzyme 1
ribonuclease 1
myosin light chain kinase 1
SPC 1
11beta-hydroxysteroid dehydrogenase 1
glutathione reductase 1
DNase 1
calpain 3 1
heme oxygenase 1
calpain 3 1
ornithine decarboxylase 1
ATP synthase 1
RNase 1
ribonucleotide reductase 1
ribonucleotide reductase 1
Lod 1
chitinase 1
15-hydroxyprostaglandin dehydrogenase 1
methionine synthase 1
cathepsin S 1
STK11 1
PARP 1
gamma-butyrobetaine hydroxylase 1
PAH 1
ACE 1
GSK 1
peptidyl-prolyl cis-trans isomerase 1
adamalysin 1
Compound
copper 216
lysine 137
Dec 91
DNA 51
Collagen 50
aldehyde 46
aldehyde 45
Clin 41
BAPN 40
oxygen 38
water 27
Elastin 26
calcium 26
tyrosine 25
sulfate 24
cysteine 22
glucose 22
proline 21
homocysteine 20
urea 20
sodium 19
hydrogen 18
MDA 15
pentosidine 15
His 13
salt 13
zinc 13
cadmium 12
Cardiol 12
ASA 12
phosphate 11
arginine 11
TNF 11
APN 11
Cu(II) 11
H2O2 10
DEAE 9
Asp 8
leucine 8
tryptophan 8
Gly 8
nitrogen 7
Pyrroloquinoline quinone 7
acetate 7
alanine 7
NH2 7
EDTA 6
iron 6
EDTA 6
retinoic acid 6
nitric oxide 6
tryptophan 6
cobalt 6
tryptophan 6
tryptophan 6
hyaluronic acid 5
potassium 5
ammonium 5
Hydroxyproline 5
SDS 5
acetic acid 5
vitamin D 5
methionine 5
Phe 5
ammonia 5
Homocysteine 4
aldosterone 4
Desmosine 4
HCl 4
PGE2 4
Ang II 4
CCl4 4
ATP 4
Homocysteine 4
guanidine 4
THP 3
GSH 3
COS 3
selenium 3
DPA 3
Pyridinoline 3
ACS 3
THP 3
DPA 3
GSH 3
DPA 3
serine 3
titanium 3
butanal 3
prostaglandin E1 3
DPA 3
Ascorbic acid 3
DPA 3
MEK 3
ACS 3
cAMP 3
benzaldehyde 2
benzaldehyde 2
PAS 2
benzaldehyde 2
glutamate 2
Vitamin D 2
DMSO 2
NADPH 2
benzaldehyde 2
benzaldehyde 2
fluorine 2
hydroxylamine 2
benzaldehyde 2
benzaldehyde 2
Triton X-100 2
benzaldehyde 2
benzaldehyde 2
benzaldehyde 2
Tyrosine 2
benzaldehyde 2
Pac 2
PEG 2
Phosphatidylcholine 2
benzaldehyde 2
valine 2
PEG 2
benzaldehyde 2
NADPH 2
benzaldehyde 2
INH 2
benzaldehyde 2
TNM 2
benzaldehyde 2
acetaldehyde 2
Homocysteine thiolactone 2
Adrenal 2
benzaldehyde 2
benzaldehyde 2
benzaldehyde 2
CCS 2
benzaldehyde 2
benzaldehyde 2
ethanol 2
2-oxoglutarate 2
hydroxylamine 2
benzaldehyde 2
benzaldehyde 2
benzaldehyde 2
dUTP 2
benzaldehyde 2
isonicotinic acid 2
5-HT 2
benzaldehyde 2
benzaldehyde 2
benzaldehyde 2
Lip 2
Ile 2
molybdenum 2
acetonitrile 2
benzaldehyde 2
benzaldehyde 2
benzaldehyde 2
Digoxin 2
Brucine 1
more...