Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.4.3.11 (glutamate dehydrogenase)
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Human Gene/Protein
glutamate dehydrogenase 12.7
glutamic dehydrogenase 12.4
GLUDP1 12.2
Glutamic dehydrogenase 11.8
GLNS 11.8
NNX3 11.8
GDH2 11.7
GLUD1 11.6
GLUD2 11.6
GDH 11.4
ZNF183 11.2
dnaK-type molecular chaperone 11.2
HADHSC 11.2
Methylmalonate semialdehyde dehydrogenase 10.8
BIII 10.5
GABA transport protein 10.2
SCHAD 10.2
NG3 10.1
glutamate dehydrogenase 1 10.0
Nucleoside diphosphokinase 10.0
NKX2-6 10.0
glutamate-ammonia ligase 9.8
Derlin-3 9.8
neurofilament triplet L protein 9.8
transcription factor NRF 9.8
phosphate-activated glutaminase 9.8
glutamine synthetase 9.7
NAD+-isocitrate dehydrogenase 9.6
M/SCHAD 9.6
glycogen phosphorylase B 9.5
glutaminase 9.4
LC8a 9.3
SLC25A10 9.3
Core protein II 9.3
pyrroline 5-carboxylate reductase 9.3
BCATm 9.3
GA protein 9.2
DN7 9.2
carbamoylphosphate synthetase I 9.2
isocitric dehydrogenase 9.2
L-alpha-glycerophosphate dehydrogenase 9.2
HADH 9.1
P5CR 9.1
DDA1 9.1
fructose-bisphosphate aldolase C 9.1
GPR80 9.1
alpha-ketoglutarate dehydrogenase 9.1
histidase 9.0
oxoglutarate 9.0
3-hydroxybutyrate dehydrogenase 8.9
SIRT4 8.9
Malic dehydrogenase 8.9
BCH 8.9
Glutamine synthetase 8.9
sorbitol dehydrogenase 8.8
GPR99 8.8
CNN3 8.8
calmodulin 2 8.8
GS2 8.8
BDB 8.7
TEB4 8.7
KGDHC 8.7
D2HGDH 8.7
integrin beta-3 8.7
malate dehydrogenase 8.6
GDI-1 8.6
NADP+-dependent malic enzyme 8.6
pyrroline-5-carboxylate reductase 8.6
aspartate dehydrogenase 8.6
NADP 8.5
HC9 8.5
AS-B 8.5
PDHC 8.5
NADP-dependent isocitrate dehydrogenase 8.4
NAD-IDH 8.4
2-oxoglutarate carrier 8.4
peptidase D 8.4
Glutaminase 8.4
Aspartate aminotransferase 8.4
2-oxoglutarate dehydrogenase 8.4
SOHLH2 8.3
phosphoserine aminotransferase 1 8.3
triosephosphate isomerase 8.3
myosin light chain 3 8.3
SLC16A1 8.3
GS1 8.3
aconitate hydratase 8.2
isocitrate dehydrogenase 8.2
Pyrroline-5-carboxylate reductase 8.2
MXD1 8.2
NP25 8.2
CHN1 8.2
serine dehydratase 8.2
ACOT2 8.2
PHT2 8.2
D-beta-hydroxybutyrate dehydrogenase 8.2
asparagine synthetase 8.1
dienoyl-CoA isomerase 8.1
transcription regulator protein 8.1
Aspartate transaminase 8.1
succinate-semialdehyde dehydrogenase 8.1
glutamate pyruvate transaminase 8.0
AMP deaminase 8.0
Malate dehydrogenase 8.0
NADP+ 8.0
succinate dehydrogenase flavoprotein subunit 8.0
BCKDH 7.9
transcription factor A, mitochondrial 7.9
fumarase 7.9
L2HGDH 7.8
adenosine monophosphate deaminase 7.8
aminoacylase 1 7.8
GNA1 7.8
mitochondrial malate dehydrogenase 7.8
NADP+-dependent isocitrate dehydrogenase 7.8
ERp46 7.8
L-3-hydroxyacyl-CoA dehydrogenase 7.8
cytosolic malate dehydrogenase 7.7
succinate semialdehyde dehydrogenase 7.7
transient receptor potential canonical 1 7.7
NADH2 7.7
G6PD protein 7.7
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase 7.7
hnRNPH 7.7
pyruvate carboxylase 7.7
NADPH2 7.7
amino acid hydroxylase 7.6
monocarboxylate transporter 2 7.6
HIS1 7.6
hVDAC1 7.6
aspartate aminotransferase 7.6
carbamoylphosphate synthetase 7.6
GDI-2 7.6
GRIA4 7.6
fructose-bisphosphatase 7.6
HEBP 7.5
AAT1 7.5
NDUFA1 7.5
cathepsin L2 7.5
NEP2 7.5
GRHPR 7.5
LEU1 7.5
NHP2 7.5
Alanine aminotransferase 7.5
3-hydroxyacyl-CoA dehydrogenase 7.4
tropomyosin 3 7.4
3-hydroxyisobutyrate dehydrogenase 7.4
P450IIE1 7.4
fructose 1,6-bisphosphatase 7.4
MDH2 7.4
GOT1 7.4
gamma-glutamyltransferase 7.4
HXB 7.3
6-phosphogluconate dehydrogenase 7.3
GLS1 7.3
ADH6 7.3
cementum protein 1 7.3
adenylosuccinate synthetase 7.3
GABA transaminase 7.3
IGL 7.3
more...
Disease
Deficiency of glutamate dehydrogenase 12.8
Acute cholestatic hepatitis 11.8
Facial eczema 9.5
Fasciola gigantica infection 9.3
yellow atrophy 9.3
BDB 9.2
GS2 8.8
Retinal dystrophy 8.6
Streptococcus suis infection 8.5
cholangiectasis 8.4
Biotin deficiency 8.4
GS1 8.3
Manganese deficiency 8.0
Giardia infections 7.9
Clostridium difficile infection 7.9
BCH 7.8
giardiasis 7.7
MGA3 7.6
Perlman syndrome 7.5
olivopontocerebellar atrophy 7.5
AAT2 7.5
megalocytosis 7.4
Extrahepatic cholestasis 7.4
alcoholic psychosis 7.3
adaptation reaction 7.0
Reye 7.0
hypoglycemic coma 6.7
pediatric disorder 6.6
Carnitine deficiency 6.6
PNP deficiency 6.6
schizophreniform psychosis 6.5
CDT 6.4
Reye's syndrome 6.4
Intestinal infection 6.3
MODY2 6.3
MD1 6.3
CBS deficiency 6.2
AOA 6.1
fascioliasis 6.1
Klebs 6.1
AAT1 6.0
ASAT 6.0
SM1 5.9
GA I 5.8
GHD 5.8
Hepatic necrosis 5.7
hyperglycinemia 5.7
ketosis 5.6
avitaminosis 5.6
hyperinsulinemia 5.6
paralytic ileus 5.6
lipidosis 5.6
GAN 5.5
hereditary ataxia 5.5
Keshan disease 5.4
EIA 5.2
megacolon 5.2
acute alcohol intoxication 5.2
US1 5.2
pseudomembranous colitis 5.1
intestinal parasites 5.1
HTX 5.1
CPL 5.0
HTX 5.0
MSF 5.0
acute alcoholic hepatitis 5.0
alkalosis 5.0
microsporidiosis 5.0
hepatic encephalopathy 4.9
SME 4.8
RSI 4.7
hepatic coma 4.7
RSS 4.7
cryptosporidiosis 4.6
JIP 4.6
Canavan 4.6
Spraying 4.5
tubular necrosis 4.5
audiogenic seizure 4.5
gastrointestinal infection 4.5
SPS 4.5
Sotos syndrome 4.4
primary hyperoxaluria 4.4
methylmalonic acidemia 4.4
alcoholic hepatitis 4.3
INS 4.3
potassium deficiency 4.3
Plasmodium falciparum infection 4.2
Crabs 4.2
hypoglycemia 4.2
PGA 4.2
Multiple system atrophy 4.1
FDH 4.1
erythropoietic protoporphyria 4.1
GAD 4.1
metabolic alkalosis 4.1
Beckwith-Wiedemann syndrome 4.1
SPS 4.1
propionic acidemia 4.1
ST3 4.0
VPI 4.0
keratocyst 4.0
ABS 4.0
ADH 4.0
vitamin E deficiency 4.0
CP1 4.0
Parry 4.0
clonorchiasis 3.9
endometritis 3.9
ABS 3.9
induced psychosis 3.9
LIP 3.8
chronic schizophrenia 3.8
Cornelia de Lange syndrome 3.8
fatty liver 3.7
TEC 3.7
PME 3.7
excessive drinking 3.7
coccidiosis 3.7
Zinc deficiency 3.6
mange 3.6
McArdle's disease 3.6
Ductal 3.6
thiamine deficiency 3.6
juvenile periodontitis 3.5
Appendix 3.5
Appendix 3.5
Appendix 3.5
KNO 3.5
Korsakoff's syndrome 3.5
toxemia 3.5
Stomach 3.4
Stomach 3.4
Stomach 3.4
Hymenolepis 3.4
hemorrhagic diathesis 3.4
emotional stress 3.4
Klebsiella 3.3
Franklin 3.3
Stomach 3.3
PNET 3.3
RP4 3.3
chlorosis 3.3
MCS 3.3
MCS 3.3
Worms 3.3
respiratory acidosis 3.3
Hepatotoxicity 3.2
DLBCL 3.2
roundworm 3.2
PDC 3.2
Wells 3.1
AMS 3.1
Schistosoma mansoni infection 3.1
panhypopituitarism 3.1
metritis 3.0
magnesium deficiency 3.0
HCI 3.0
MAR 3.0
Machado-Joseph disease 3.0
more...
Symptom
Upper back pain 10.2
Central pain 7.1
ACHE 4.9
dark urine 4.7
starvation 4.1
ataxic gait 3.7
Anoxia 3.7
cerebellar ataxia 3.6
diarrhea 3.3
general problem 3.1
nasal congestion 2.7
hypotonia 2.6
Mills 2.5
HSA 2.3
anosmia 2.2
dystonia 2.1
anorexia 2.1
ataxia 2.0
hypothermia 1.7
exhaustion 1.7
seizures 1.5
hepatomegaly 1.3
acute abdomen 1.2
bone pain 1.2
flushing 1.2
memory loss 1.0
cyanosis 0.9
hepatosplenomegaly 0.7
acidity 0.5
shortness of breath 0.5
hyperoxia 0.5
cachexia 0.3
abdominal pain 0.2
tremor -0.4
weakness -0.4
nausea and vomiting -0.4
fatigue -0.5
vomiting -0.6
thinning -0.6
stigma -0.9
functional recovery -0.9
analgesia -1.0
cough -1.7
anesthesia -1.9
dyspnea -2.0
collapse -2.0
pain -2.6
headache -3.0
Drug
Lifarizine 10.0
Butylamine 10.0
Bidisomide 9.8
Methscopolamine 9.3
Duphalac 8.9
Giardiasis 7.9
Pegaspargase 7.6
Omapatrilat 7.6
NADH 7.1
Atabrine 6.9
Asparaginase 6.8
Cibacron Blue 6.2
Sodium thiosulfate 6.2
Tween 40 6.2
Perphenazine 6.1
Ammonium chloride 5.9
Alanine 5.8
Glutamic acid 5.8
Fenbendazole 5.5
Pentostam 5.4
Guanidine 5.4
Guanidine 5.4
NH3 5.2
FAD 5.1
Calcium chloride 5.0
pyridoxal phosphate 4.8
Propidium 4.8
Pyridoxal 4.8
Cellulose acetate 4.7
Troglitazone 4.7
Clofibrate 4.7
citric acid 4.7
Lactase 4.7
Sodium valproate 4.5
Flavin 4.4
Mycophenolic acid 4.4
Galactose 4.4
Piracetam 4.4
Fructose 4.2
Gabapentin 4.0
Cellulase 3.8
G418 3.7
Salicylate 3.7
Streptokinase 3.7
PPA 3.6
Vitamin B12 3.5
Vitamin B 3.5
Scopolamine 3.5
lysine 3.4
Phosphatidylserine 3.4
Adenosine deaminase 3.4
Zoledronic acid 3.2
CaCl2 3.1
Adenosine triphosphate 3.0
CaCl2 3.0
CaCl2 3.0
Gastro 3.0
THA 3.0
Gel 2.9
Check 2.8
-deoxyadenosine 2.8
AraC 2.8
DMAP 2.7
Capsicum 2.7
Albumin 2.6
Horizon 2.6
ascorbate 2.6
Ethanol 2.6
Glucagon 2.5
Arsenic trioxide 2.5
NBT 2.4
Glutathione 2.4
ALA 2.3
Glycyrrhiza 2.3
IPM 2.3
Vitamin A 2.2
MgSO4 2.2
GEO 2.2
VCR 2.2
MIL 2.2
TAC 2.1
Vitamin E 2.1
Asn 2.1
Diurnal 2.1
Parkin 1.9
Parkin 1.9
Frontal 1.8
NAG 1.7
DHT 1.7
Estrogens 1.7
DHT 1.6
Glycerol 1.6
Fragment 1.6
L-tyrosine 1.6
TAT 1.6
Leaf 1.6
Fraction 1.5
ROC 1.5
Fluorescein 1.4
DNase I 1.4
lactose 1.4
Ringer's solution 1.3
vitamin E 1.3
ABC 1.3
Kenyan 1.0
PCP 1.0
Fluorescein 0.9
niacin 0.9
THF 0.8
PCB 0.8
SiO2 0.3
CSF 0.2
PTH 0.1
EPA -0.0
EE2 -0.1
ENT -0.3
nitroglycerin -0.3
Nephron -0.3
caffeine -0.6
TiO2 -0.7
Nephron -0.7
ampicillin -1.2
IFN-gamma -2.0
Monit -2.3
Dermatol -5.2
Enzyme
glutamate dehydrogenase 12.8
lysine transcarbamylase 12.8
glutamate dehydrogenase 12.8
glutamate dehydrogenase 12.8
glutamic dehydrogenase 12.7
EC 2.6.1.14 11.8
glutamate synthase 11.3
glutamate synthase 11.3
glutamate synthase 11.3
neprilysin-2 11.2
glutaminase II 10.7
omega-amidase 10.6
lactoyl-CoA dehydratase 10.5
alanine dehydrogenase 10.0
EC 2.7.7.42 10.0
glutarate semialdehyde dehydrogenase 10.0
glycerophosphate phosphatase 10.0
creatinine iminohydrolase 10.0
leucine dehydrogenase 9.9
lysine epsilon-aminotransferase 9.9
glutamine synthetase 9.7
L-asparagine synthetase 9.6
2-oxoisovalerate dehydrogenase 9.5
glutaminase 9.4
KGOR 9.3
EC 4.3.1.2 9.3
aminopeptidase W 9.3
EC 2.6.1.4 9.3
beta-hydroxybutyrate dehydrogenase 9.2
EC 1.7.7.1 9.2
cefG 9.1
EC 2.3.2.1 9.0
histidase 8.9
trehalose phosphate synthase 8.9
2-oxoglutarate decarboxylase 8.9
branched-chain aminotransferase 8.9
alpha-ketoglutarate dehydrogenase 8.8
Xsc 8.8
4-hydroxybutyrate dehydrogenase 8.8
glutamine transaminase K 8.8
sorbitol dehydrogenase 8.7
2-hydroxyglutarate dehydrogenase 8.7
EC 3.6.1.29 8.7
leucine aminotransferase 8.6
carboxylate reductase 8.6
AMP deaminase 8.6
creatininase 8.6
aspartate dehydrogenase 8.6
lombricine kinase 8.6
proline oxidase 8.5
YgjG 8.5
EC 1.1.1.39 8.5
DHOdehase 8.4
D-xylose dehydrogenase 8.4
tropinone reductase 8.4
malate dehydrogenase 8.4
aspartase 8.4
energy-linked transhydrogenase 8.3
isocitrate dehydrogenase 8.3
BCKDH 8.3
valine dehydrogenase 8.3
carbamoylphosphate synthetase 8.2
4-hydroxy-2-oxoglutarate aldolase 8.2
ComC 8.2
allantoate amidohydrolase 8.2
sulfur reductase 8.2
asparagine synthetase 8.2
isocitrate dehydrogenase 8.1
triose-phosphate isomerase 8.1
YdcW 8.1
GDPase 8.0
phenylacetyl-CoA ligase 7.9
creatinase 7.9
methylmalonate-semialdehyde dehydrogenase 7.9
hydroxylamine reductase 7.8
hydroxylamine reductase 7.8
propionyl-CoA transferase 7.8
oxoglutarate dehydrogenase 7.8
threonine dehydrogenase 7.8
diaminopimelate dehydrogenase 7.8
nitrate reductase 7.7
nitrate reductase 7.7
nitrate reductase 7.7
nitrate reductase 7.7
nitrate reductase 7.7
nitrate reductase 7.7
ornithine aminotransferase 7.7
pyruvate carboxylase 7.7
dihydrolipoamide succinyltransferase 7.7
L-amino-acid oxidase 7.6
nitrite reductase 7.6
nitrite reductase 7.6
5beta-reductase 7.6
putrescine oxidase 7.6
acetate CoA-transferase 7.6
nitrite reductase 7.6
glutamate mutase 7.5
pyrroline-5-carboxylate dehydrogenase 7.5
fumarase 7.5
glyoxylate reductase 7.5
3-hydroxyisobutyrate dehydrogenase 7.5
glyoxylate reductase 7.5
oxaloacetate decarboxylase 7.4
staphopain 7.4
6-phosphogluconate dehydrogenase 7.4
6-phosphogluconate dehydrogenase 7.4
NAAT 7.3
proline dehydrogenase 7.3
GABA transaminase 7.3
aromatic amino acid aminotransferase 7.3
glycerol-3-phosphate dehydrogenase 7.3
guanase 7.3
lactate oxidase 7.3
aureolysin 7.2
dihydrodipicolinate reductase 7.2
EC 2.4.1.11 7.2
3-hydroxyacyl-CoA dehydrogenase 7.2
SsuE 7.2
glycerol-3-phosphate dehydrogenase 7.2
aspartate aminotransferase 7.2
succinic semialdehyde dehydrogenase 7.2
glycerol 3-phosphate dehydrogenase 7.2
lipoate acetyltransferase 7.2
glutamate decarboxylase 7.2
inositol dehydrogenase 7.1
citrate synthase 7.1
phosphoenolpyruvate carboxykinase 7.1
3-hydroxyacyl-CoA dehydrogenase 7.1
adenylosuccinate synthetase 7.1
phosphoenolpyruvate carboxykinase 7.1
GPH 7.0
glucokinase 7.0
fructose 1,6-bisphosphatase 7.0
phosphoglucose isomerase 7.0
glycolate dehydrogenase 7.0
formamidase 7.0
allantoicase 7.0
pyruvate:ferredoxin oxidoreductase 7.0
phosphoenolpyruvate carboxykinase 6.9
isocitrate lyase 6.9
N-acetylglutamate kinase 6.9
carbamate kinase 6.9
transglucosylase 6.9
allantoinase 6.9
glutamate racemase 6.9
arginase 6.9
adenylosuccinate lyase 6.8
6-phosphogluconate dehydratase 6.8
cathepsin V 6.8
glucose-6-phosphate dehydrogenase 6.8
hydroxypyruvate reductase 6.8
tripeptidase 6.8
phosphoenolpyruvate synthase 6.8
SBPase 6.8
succinate dehydrogenase 6.8
hexokinase 6.7
aspartate semialdehyde dehydrogenase 6.7
succinyl-CoA synthetase 6.7
EC 1.1.1.40 6.7
ornithine transcarbamylase 6.7
more...
Compound
3-hydroxy-4-pentenenitrile 12.8
Asparagusate 11.8
6-hydroxynorleucine 11.6
6-hydroxynorleucine 11.6
6-hydroxynorleucine 11.6
Kievitone 10.5
Meldola's Blue 10.5
cholest-7-en-3-one 10.5
Acid Red 151 10.5
Succinic acid monomethyl ester 10.2
C6H10O4 10.2
alpha-ketoglutaramate 10.1
Homocitrulline 10.0
Pteroic acid 10.0
Meldola's Blue 9.9
Trithion 9.6
Methionine sulfoximine 9.5
hexanediamide 9.5
N-methyl-lysine 9.5
6-hydroxyhexanoic acid 9.3
D-Glutamine 9.3
(aminooxy)acetic acid 9.3
5-methylisophthalic acid 9.3
Diglycerol 9.2
Rafoxanide 9.2
2-oxoglutarate 9.2
Butylamine 9.1
3'-Hydroxyacetanilide 9.1
5-oxohexanoic acid 9.1
2-Oxoglutarate 8.9
TNBT 8.9
glutamic gamma-semialdehyde 8.7
2,4-DA 8.7
2-keto-4-hydroxyglutarate 8.6
D-Leucine 8.6
Woodward's Reagent K 8.6
Thiamine triphosphate 8.4
Phenylpyruvate 8.4
Thiamine triphosphate 8.4
dimethyl malate 8.3
NADP 8.3
norvaline 8.2
GAH 8.2
Chlorophyllide 8.2
norvaline 8.2
Glutamate 8.1
3-MPA 8.0
oxalacetate 7.9
Ethoxzolamide 7.9
Glutamine 7.8
Glutaric acid 7.7
2-methylcitric acid 7.7
2-oxoadipate 7.6
alpha-ketoisocaproate 7.5
Phenylglyoxal 7.4
carbamyl phosphate 7.4
pyrroline-5-carboxylate 7.4
Homotaurine 7.3
Azaserine 7.3
Amastatin 7.3
Cephaloridine 7.3
glutamine 7.3
2-keto-3-deoxy-6-phosphogluconate 7.3
acetylglutamate 7.3
pentanedioic acid 7.2
ED 20 7.2
cysteate 7.2
NAD 7.2
L-leucine 7.2
NAD 7.1
alpha-isopropylmalate 7.1
NADH 7.1
glutamate 7.1
Chymostatin 7.1
N-acetylserine 7.0
HFr 7.0
isocitrate 6.9
1,2-cyclohexanedione 6.9
2-oxobutyrate 6.9
adenylosuccinate 6.9
fructose-1-phosphate 6.9
2-heptanol 6.8
N-acetylaspartic acid 6.8
isoguanine 6.7
Ornithine 6.7
Azocoll 6.7
N-acetylaspartic acid 6.7
DDMU 6.7
norleucine 6.6
Hygromycin B 6.6
NMN 6.6
ammonia 6.6
2-oxobutyrate 6.6
Succinyl-CoA 6.5
hydroxyglutarate 6.5
D-Galactosamine 6.5
Amido black 6.4
propionyl-coenzyme A 6.4
CDT 6.4
allantoate 6.4
KIV 6.4
Leucine 6.3
2-ethylhexanoic acid 6.3
2-ethylhexanoic acid 6.3
norleucine 6.3
butyryl-CoA 6.3
ornithine 6.3
ornithine 6.3
ornithine 6.3
ornithine 6.3
ornithine 6.3
2-ethylhexanoic acid 6.3
NADPH 6.3
NADPH 6.2
Pipecolic acid 6.2
DMAE 6.2
keto-gamma 6.2
dihydroxyacetone-phosphate 6.2
Danshensu 6.1
pentitol 6.1
S-sulfocysteine 6.1
BDH 6.1
Carmine 6.1
nicotinamide 6.0
Malate 6.0
CeCl3 6.0
isophthalic acid 6.0
palmitoyl-CoA 6.0
Allantoin 5.9
Allantoin 5.9
2-ethylhexanoic acid 5.9
N-F 5.9
Alanine 5.9
alcohol dehydrogenase 5.8
1,2-cyclohexanediamine 5.8
1,2-cyclohexanediamine 5.8
O,O-diethyl 5.8
pentitol 5.8
DCIP 5.8
pentitol 5.8
A 150 5.8
2-heptanol 5.7
Pyruvate 5.7
ammonium 5.7
piperidine-2-carboxylic acid 5.7
Lomefloxacin 5.6
phthalonitrile 5.6
2-phosphoglycerate 5.6
DCVC 5.5
heptane 5.5
Diazoxide 5.5
2,5-furandicarboxylic acid 5.5
DPN 5.5
glutamic acid 5.4
Gossypol 5.4
GPT 5.4
Gossypol 5.4
MNE 5.4
bromobenzene 5.4
ANI 5.3
more...