Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.4.3.11 (glutamate dehydrogenase)
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Human Gene/Protein
glutamate dehydrogenase 4163
glutamine synthetase 571
NAD 416
aspartate aminotransferase 399
NADH 398
NADP 364
Sep 332
lactate dehydrogenase 296
NADPH 263
alanine aminotransferase 244
Mol 242
GDH 241
ATP 220
ADP 208
malate dehydrogenase 204
insulin 181
glutaminase 173
glutamic dehydrogenase 173
GTP 150
alkaline phosphatase 139
isocitrate dehydrogenase 124
NAD+ 121
NADP+ 99
glucose-6-phosphate dehydrogenase 99
citrate synthase 82
catalase 80
hexokinase 79
pyruvate kinase 69
alcohol dehydrogenase 68
A-I 67
polypeptide 63
phosphoenolpyruvate carboxykinase 63
sorbitol dehydrogenase 63
albumin 61
creatine kinase 58
triosephosphate isomerase 57
acid phosphatase 55
CO2 54
Gen 52
glucokinase 51
oxidoreductase 50
peroxidase 49
GABA 49
ATPase 48
alpha-ketoglutarate dehydrogenase 47
GLUD1 45
gamma-glutamyltransferase 44
AII 44
TCA 43
glutamate decarboxylase 42
Glutamine synthetase 42
phosphate-activated glutaminase 41
AMP 41
glucose-6-phosphatase 40
pyruvate carboxylase 40
phosphofructokinase 36
glutamate pyruvate transaminase 36
SDS 36
superoxide dismutase 36
Pseudomonas 35
pyruvate dehydrogenase 34
glyceraldehyde-3-phosphate dehydrogenase 33
6-phosphogluconate dehydrogenase 32
serum albumin 31
gamma-glutamyl transpeptidase 31
NMR 31
endoplasmic reticulum 30
esterase 30
reductase 30
GDH2 29
microsomal 29
hemoglobin 29
FAD 27
cytochrome c oxidase 26
fumarase 25
cytochrome 25
BIII 24
GSH 24
glutathione reductase 24
oxoglutarate 23
2-oxoglutarate dehydrogenase 23
BCH 23
phosphoenolpyruvate carboxylase 22
phosphatase 21
cytochrome c 21
NO3 20
aldehyde dehydrogenase 20
AST 20
acetylcholinesterase 19
AMP deaminase 19
Aspartate aminotransferase 19
LDH 19
glutathione S-transferase 19
aconitase 18
adenylate kinase 18
Kir6.2 18
ornithine aminotransferase 18
GLUD2 18
asparagine synthetase 18
collagenase 18
glycoprotein 18
glucagon 18
GABA transaminase 17
sulfonylurea receptor 17
pyruvate dehydrogenase complex 17
ferredoxin 17
leucine aminopeptidase 16
kit 16
gamma-glutamyltranspeptidase 16
proximal tubule 16
adenosine deaminase 16
glial fibrillary acidic protein 15
mTOR 15
glutathione peroxidase 15
OTC 15
threonine 15
gut 15
housekeeping 15
phosphoglucose isomerase 15
SUR1 14
5'-nucleotidase 14
histidase 14
beta-glucuronidase 14
GPT 14
enolase 14
lipase 14
isocitric dehydrogenase 14
Rec 14
BCATm 14
amylase 14
PHI 14
Bot 13
caspase-3 13
fibrinogen 13
carbonic anhydrase 13
Alanine aminotransferase 13
TAT 13
haptoglobin 13
diaphorase 13
3-hydroxyacyl-CoA dehydrogenase 13
GS1 12
D-amino acid oxidase 12
fused 12
membrane-bound 12
NADP-dependent isocitrate dehydrogenase 12
lysozyme 12
adenosine triphosphatase 12
GS2 12
PK1 11
heat shock protein 11
PEG 11
carbamoylphosphate synthetase 11
ACS 11
collagen 11
glutamate binding 11
SIRT4 11
histone 11
TOF 10
ubiquinone 10
aminopeptidase 10
more...
Disease
hyperinsulinemia 72
diabetes 70
cancer 56
hypoglycemia 55
ischemia 48
Clostridium difficile infection 48
giardiasis 48
tumor 47
cold 42
SDS 36
liver disease 32
Klebsiella 31
fatty liver 26
cirrhosis 26
GSH 24
BCH 23
Alzheimer's disease 22
depression 21
malaria 19
hepatic encephalopathy 18
epilepsy 18
Parkinson's disease 16
hepatocellular carcinoma 15
EIA 15
ketosis 14
infectious diseases 13
hepatitis 13
GS1 12
Infection 12
schizophrenia 12
alcoholism 12
olivopontocerebellar atrophy 12
type 2 diabetes 12
GS2 12
fascioliasis 11
Reye's syndrome 10
alkalosis 10
sepsis 10
colitis 9
encephalopathy 9
hyperglycemia 9
tumor growth 9
cholestasis 9
Mycobacterium 9
BDB 9
coma 8
PGA 8
tuberculosis 8
obesity 8
intestinal parasites 8
breast cancer 8
cryptosporidiosis 8
cognitive impairment 8
fits 7
chronic hepatitis 7
mole 7
glioma 7
sepsis 7
carcinoma 7
adenocarcinoma 7
mole 7
worms 6
GAD 6
alcohol abuse 6
Proteus 6
SEM 6
megacolon 6
cerebral ischemia 6
virus infection 6
pseudomembranous colitis 5
anemia 5
temporal lobe epilepsy 5
malnutrition 5
CDT 5
Infections 5
viral hepatitis 5
endometritis 5
lipidosis 5
iron deficiency 5
Best 5
neuroblastoma 5
ADH 5
parkinsonism 4
amyotrophic lateral sclerosis 4
Chagas 4
INS 4
genetic disorder 4
heart failure 4
SM1 4
tubular necrosis 4
alcoholic hepatitis 4
AOA 4
emotional stress 4
eczema 4
dementia 4
mental retardation 4
hypertension 4
primary biliary cirrhosis 4
dehydration 4
neurological disease 4
paralytic ileus 4
hypoglycemic coma 4
hyperlipidemia 4
zoonosis 4
periodontitis 4
mental retardation 4
Giardia infections 4
stroke 4
gastroenteritis 4
West 4
ASAT 4
metabolic alkalosis 4
liver fibrosis 4
Placenta 3
eosinophilia 3
ileus 3
metastases 3
coccidiosis 3
insulinoma 3
renal failure 3
motor neuron disease 3
chronic schizophrenia 3
PCC 3
acute hepatitis 3
NHS 3
pheochromocytoma 3
Yersinia 3
chlorosis 3
pancreatitis 3
status epilepticus 3
progressive supranuclear palsy 3
memory impairment 3
dyspepsia 3
Reye 3
glucose intolerance 3
Biotin deficiency 3
meningitis 3
parasitic disease 3
hypercholesterolemia 3
glioblastoma 3
metabolic syndrome 3
Beckwith-Wiedemann syndrome 3
immunodeficiency 3
carcinogenesis 3
cardiovascular disease 3
Poland 3
squamous cell carcinoma 3
Brown 3
HIV 3
mastitis 3
gastrointestinal disease 3
uterus 3
gastric cancer 3
developmental delay 3
Still 3
arthritis 3
lung cancer 2
alcoholic fatty liver 2
growth hormone deficiency 2
SPS 2
more...
Symptom
diarrhea 79
starvation 61
seizures 31
ataxia 9
anorexia 8
hypothermia 8
cerebellar ataxia 6
pain 6
exhaustion 6
fatigue 5
hypotonia 5
abdominal pain 5
dystonia 5
weakness 4
anesthesia 4
vomiting 3
acidity 3
HSA 2
tremor 2
hepatomegaly 2
analgesia 2
flushing 2
cough 1
Mills 1
hyperoxia 1
general problem 1
dyspnea 1
Central pain 1
cyanosis 1
shortness of breath 1
memory loss 1
ataxic gait 1
Upper back pain 1
dark urine 1
thinning 1
hepatosplenomegaly 1
anosmia 1
functional recovery 1
bone pain 1
cachexia 1
acute abdomen 1
collapse 1
Anoxia 1
stigma 1
headache 1
nasal congestion 1
ACHE 1
nausea and vomiting 1
Drug
NADH 409
lysine 89
NH3 37
citric acid 35
FAD 27
Alanine 22
ascorbate 19
Gel 15
pyridoxal phosphate 10
Leaf 9
Ethanol 8
Giardiasis 8
CaCl2 8
Asn 7
CaCl2 7
CaCl2 7
lactose 6
vitamin E 6
CSF 5
Cibacron Blue 5
Fructose 5
Albumin 4
Asparaginase 4
Glutathione 4
G418 4
Glutamic acid 4
Glucagon 3
DNase I 3
ABC 3
ROC 3
Galactose 3
-deoxyadenosine 2
Ammonium chloride 2
Omapatrilat 2
Nephron 2
Capsicum 2
Gabapentin 2
Vitamin B 2
Guanidine 2
Guanidine 2
THF 2
Vitamin A 2
ALA 2
caffeine 2
Clofibrate 2
Tween 40 2
Vitamin B12 2
Vitamin E 2
Check 2
Troglitazone 2
Scopolamine 2
EPA 1
niacin 1
Adenosine triphosphate 1
Estrogens 1
Zoledronic acid 1
AraC 1
Calcium chloride 1
Parkin 1
SiO2 1
Frontal 1
Lifarizine 1
Sodium thiosulfate 1
ampicillin 1
VCR 1
IPM 1
GEO 1
Mycophenolic acid 1
Gastro 1
L-tyrosine 1
Horizon 1
Lactase 1
Kenyan 1
Monit 1
Dermatol 1
Fluorescein 1
ENT 1
NBT 1
Parkin 1
Flavin 1
IFN-gamma 1
Methscopolamine 1
Pegaspargase 1
Propidium 1
PCP 1
Atabrine 1
Streptokinase 1
EE2 1
Ringer's solution 1
THA 1
Phosphatidylserine 1
MIL 1
Perphenazine 1
Glycerol 1
PCB 1
Butylamine 1
Fluorescein 1
Arsenic trioxide 1
Salicylate 1
Cellulase 1
TAC 1
NAG 1
Duphalac 1
Fragment 1
DHT 1
Fraction 1
Cellulose acetate 1
TAT 1
Sodium valproate 1
Pyridoxal 1
PPA 1
PTH 1
Piracetam 1
Adenosine deaminase 1
Bidisomide 1
Glycyrrhiza 1
nitroglycerin 1
MgSO4 1
Nephron 1
Diurnal 1
DMAP 1
Pentostam 1
TiO2 1
DHT 1
Fenbendazole 1
Enzyme
glutamate dehydrogenase 4437
glutamate dehydrogenase 4278
glutamate dehydrogenase 4278
glutamine synthetase 579
aspartate aminotransferase 438
alanine aminotransferase 328
lactate dehydrogenase 325
glutamate synthase 282
glutamate synthase 275
glutamate synthase 269
malate dehydrogenase 218
glutamic dehydrogenase 204
glutaminase 178
alkaline phosphatase 141
isocitrate dehydrogenase 138
isocitrate dehydrogenase 132
succinate dehydrogenase 123
glucose-6-phosphate dehydrogenase 120
nitrate reductase 115
gamma-glutamyl transpeptidase 111
nitrate reductase 110
nitrate reductase 110
nitrate reductase 110
nitrate reductase 110
nitrate reductase 110
citrate synthase 87
phosphoenolpyruvate carboxykinase 81
catalase 80
phosphoenolpyruvate carboxykinase 80
alpha-ketoglutarate dehydrogenase 80
hexokinase 79
phosphoenolpyruvate carboxykinase 79
alcohol dehydrogenase 77
pyruvate kinase 70
creatine kinase 68
urease 67
peroxidase 65
sorbitol dehydrogenase 64
cytochrome oxidase 62
urease 62
ATPase 60
arginase 60
acid phosphatase 57
pyruvate dehydrogenase 56
diaphorase 55
nitrite reductase 52
glucokinase 52
nitrite reductase 51
nitrite reductase 51
glyceraldehyde-3-phosphate dehydrogenase 46
acetylcholinesterase 45
trypsin 43
glutamate decarboxylase 43
pyruvate carboxylase 43
superoxide dismutase 41
phosphofructokinase 41
glyceraldehyde-3-phosphate dehydrogenase 41
CPR 41
glucose-6-phosphatase 41
monoamine oxidase 39
alanine dehydrogenase 39
glycerol-3-phosphate dehydrogenase 38
AMP deaminase 37
glycerol-3-phosphate dehydrogenase 37
glyceraldehyde-3-phosphate dehydrogenase 36
glyceraldehyde-3-phosphate dehydrogenase 35
pyruvate dehydrogenase 34
pyruvate dehydrogenase 34
cholinesterase 34
6-phosphogluconate dehydrogenase 33
6-phosphogluconate dehydrogenase 33
adenosine deaminase 33
glyceraldehyde-3-phosphate dehydrogenase 33
aldolase 32
beta-hydroxybutyrate dehydrogenase 31
phosphoglucose isomerase 30
fumarase 29
ornithine transcarbamylase 25
glutathione reductase 24
aconitase 23
succinic dehydrogenase 22
glutathione S-transferase 22
phosphoenolpyruvate carboxylase 22
ornithine aminotransferase 21
AST 21
aldehyde dehydrogenase 21
glucose oxidase 20
asparagine synthetase 20
diaphorase 20
aldehyde dehydrogenase 20
NADPH-diaphorase 20
aldehyde dehydrogenase 20
aldehyde dehydrogenase 20
aldehyde dehydrogenase 20
adenylate kinase 18
CPS 18
collagenase 18
GABA transaminase 18
isocitrate lyase 17
leucine aminopeptidase 17
nitrogenase 17
ATP synthase 17
complex I 16
tyrosine aminotransferase 16
adenosine deaminase 16
lipase 16
phosphorylase 16
ACS 16
histidase 16
branched-chain aminotransferase 15
chymotrypsin 15
RNA polymerase 15
lysozyme 15
enolase 15
glutathione peroxidase 15
NQO1 14
asparaginase 14
beta-glucuronidase 14
beta-galactosidase 14
5'-nucleotidase 14
fructose 1,6-bisphosphatase 14
3-hydroxyacyl-CoA dehydrogenase 14
proline oxidase 14
carbamoylphosphate synthetase 13
3-hydroxyacyl-CoA dehydrogenase 13
leucine dehydrogenase 13
carbonic anhydrase 12
phosphoglucomutase 12
xanthine oxidase 11
ascorbate oxidase 10
uricase 10
PHD 10
aspartase 10
MDH 10
MDH 10
AMP-activated protein kinase 10
glucose dehydrogenase 9
pyruvate decarboxylase 9
AMPK 9
protein kinase 9
caspase-3 9
alpha-glucosidase 9
hydrogenase 9
hydrogenase 9
RNase 9
transhydrogenase 8
invertase 8
hexosaminidase 8
mitogen-activated protein kinase 8
argininosuccinate synthetase 8
demethylase 8
lactate oxidase 8
NADPH oxidase 8
deaminase 8
alpha-amylase 7
proline dehydrogenase 7
triose-phosphate isomerase 7
UDP-glucuronosyltransferase 7
formate dehydrogenase 7
luciferase 7
more...
Compound
glutamate 1365
nitrogen 593
2-oxoglutarate 590
ammonia 588
glutamine 580
NAD 518
glucose 493
NADP 483
ammonium 462
NAD 416
NADH 409
phosphate 383
Dec 313
alanine 295
NADPH 269
urea 263
NADPH 263
Glutamate 240
DNA 234
ATP 220
ADP 216
ADP 210
ADP 208
Clin 204
NH2 162
leucine 157
water 153
GTP 151
nicotinamide 147
nitrate 145
oxygen 140
sodium 117
methionine 116
calcium 112
arginine 106
lysine 103
proline 102
glutamic acid 98
acetate 94
hydrogen 82
potassium 77
ethanol 77
ornithine 74
ornithine 74
ornithine 74
ornithine 74
ornithine 74
salt 72
sulfate 70
alcohol dehydrogenase 68
CO2 64
cysteine 62
Glutamine 61
His 58
creatinine 52
Asp 51
asparagine 51
GABA 50
serine 50
GABA 49
CoA 49
L-leucine 49
AMP 46
TCA 44
galactose 44
zinc 44
Phe 44
tyrosine 42
iron 42
glycerol 40
valine 40
tryptophan 39
SDS 39
tryptophan 39
tryptophan 36
tryptophan 36
Ile 34
Gly 33
gamma-aminobutyric acid 33
PEG 31
copper 31
aspartic acid 31
pentose 30
pentose 30
pentose 30
pentose 30
isoleucine 29
isocitrate 29
isoleucine 28
FAD 28
Leucine 27
GSH 26
GSH 26
PEG 25
acetyl-CoA 25
oxalacetate 25
phosphorus 25
aldehyde 24
Mg2+ 24
threonine 23
aspartic acid 22
Alanine 22
aspartic acid 22
pyridine 22
aspartic acid 22
Lactate 22
guanidine 22
bromide 21
NO3 20
DEAE 20
cadmium 20
heptane 20
acrylamide 19
methanol 19
Insulin 18
norvaline 18
cyanide 18
H2O2 18
norvaline 18
alpha-ketoisocaproate 17
glucose-6-phosphate 17
acetaldehyde 16
acetic acid 15
Triton X-100 15
cAMP 15
EDTA 14
CCl4 14
palmitoyl-CoA 14
Tris 14
HCl 14
hydroxylamine 14
Optimal 14
Pyruvate 14
EDTA 14
hydroxylamine 14
GPT 14
succinic acid 14
Tris 13
carbamyl phosphate 13
nitric oxide 12
adenylate 12
norleucine 12
norleucine 12
alloxan 12
hydroxyglutarate 12
Nitrate 12
hexose 11
ACS 11
ACS 11
hexose 11
hexose 11
dicarboxylic acid 11
selenium 11
hexose 11
butyric acid 10
TOF 10
ubiquinone 10
butyric acid 10
silver 10
sodium chloride 10
more...