Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.4.1.2 (glutamate dehydrogenase)
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Human Gene/Protein
glutamate dehydrogenase 4165
glutamine synthetase 584
NAD 432
NADH 420
aspartate aminotransferase 399
NADP 376
Sep 323
lactate dehydrogenase 298
NADPH 279
GDH 265
Mol 244
alanine aminotransferase 242
ATP 223
ADP 216
malate dehydrogenase 205
insulin 181
glutamic dehydrogenase 174
glutaminase 168
GTP 154
alkaline phosphatase 140
NAD+ 129
isocitrate dehydrogenase 126
NADP+ 104
glucose-6-phosphate dehydrogenase 101
citrate synthase 82
hexokinase 79
catalase 72
pyruvate kinase 69
alcohol dehydrogenase 68
A-I 68
sorbitol dehydrogenase 63
phosphoenolpyruvate carboxykinase 63
polypeptide 62
albumin 61
creatine kinase 58
triosephosphate isomerase 57
Gen 55
acid phosphatase 55
CO2 53
oxidoreductase 52
GABA 52
glucokinase 51
ATPase 50
Glutamine synthetase 48
alpha-ketoglutarate dehydrogenase 48
GLUD1 45
AMP 44
gamma-glutamyltransferase 44
AII 44
TCA 44
glutamate decarboxylase 42
phosphate-activated glutaminase 41
glucose-6-phosphatase 40
pyruvate carboxylase 40
SDS 37
superoxide dismutase 37
phosphofructokinase 36
glutamate pyruvate transaminase 35
Pseudomonas 35
glyceraldehyde-3-phosphate dehydrogenase 34
pyruvate dehydrogenase 34
6-phosphogluconate dehydrogenase 32
reductase 31
endoplasmic reticulum 31
NMR 31
GDH2 31
gamma-glutamyl transpeptidase 31
hemoglobin 30
microsomal 29
esterase 29
cytochrome c oxidase 28
FAD 27
cytochrome 27
peroxidase 26
fumarase 26
BIII 24
glutathione reductase 24
GSH 24
2-oxoglutarate dehydrogenase 23
BCH 23
oxoglutarate 23
NO3 22
phosphatase 22
phosphoenolpyruvate carboxylase 22
cytochrome c 21
LDH 21
aldehyde dehydrogenase 20
asparagine synthetase 20
AST 20
ferredoxin 19
serum albumin 19
ornithine aminotransferase 19
AMP deaminase 19
acetylcholinesterase 19
Aspartate aminotransferase 19
glutathione S-transferase 19
adenylate kinase 18
collagenase 18
aconitase 18
pyruvate dehydrogenase complex 18
glucagon 18
glycoprotein 18
GLUD2 18
Kir6.2 18
sulfonylurea receptor 17
GABA transaminase 17
leucine aminopeptidase 16
GPT 16
phosphoglucose isomerase 16
gamma-glutamyltranspeptidase 16
proximal tubule 16
adenosine deaminase 16
histidase 15
threonine 15
beta-glucuronidase 15
glutathione peroxidase 15
gut 15
OTC 15
isocitric dehydrogenase 15
amylase 15
mTOR 15
housekeeping 15
glial fibrillary acidic protein 15
BCATm 15
5'-nucleotidase 14
SUR1 14
membrane-bound 14
lipase 14
haptoglobin 14
Rec 14
enolase 14
PHI 14
Bot 13
carbonic anhydrase 13
glutamic acid decarboxylase 13
Alanine aminotransferase 13
fused 13
fibrinogen 13
kit 13
lysozyme 13
TAT 13
caspase-3 13
3-hydroxyacyl-CoA dehydrogenase 13
GS2 13
GS1 12
diaphorase 12
NADP-dependent isocitrate dehydrogenase 12
adenosine triphosphatase 12
ubiquinone 11
heat shock protein 11
ornithine transcarbamylase 11
glutamate binding 11
collagen 11
histone 11
SIRT4 11
PK1 11
carbamoylphosphate synthetase 11
DTNB 11
TOF 10
aminopeptidase 10
more...
Disease
hyperinsulinemia 72
diabetes 71
cancer 56
hypoglycemia 55
giardiasis 48
Clostridium difficile infection 48
tumor 48
cold 42
ischemia 39
SDS 37
liver disease 32
Klebsiella 31
cirrhosis 26
fatty liver 26
GSH 24
BCH 23
depression 22
Alzheimer's disease 22
malaria 19
hepatic encephalopathy 18
epilepsy 16
Parkinson's disease 16
hepatocellular carcinoma 15
EIA 15
hepatitis 14
ketosis 14
infectious diseases 13
GS2 13
olivopontocerebellar atrophy 12
Infection 12
GS1 12
type 2 diabetes 12
alcoholism 11
fascioliasis 11
schizophrenia 11
alkalosis 10
Reye's syndrome 10
sepsis 10
colitis 9
tumor growth 9
hyperglycemia 9
BDB 9
cholestasis 9
encephalopathy 9
Mycobacterium 9
intestinal parasites 8
breast cancer 8
coma 8
tuberculosis 8
cryptosporidiosis 8
obesity 8
cognitive impairment 8
carcinoma 8
PGA 8
adenocarcinoma 7
SEM 7
chronic hepatitis 7
worms 7
GAD 7
sepsis 7
mole 7
mole 7
fits 7
virus infection 6
alcohol abuse 6
Proteus 6
megacolon 6
pseudomembranous colitis 5
neuroblastoma 5
dementia 5
parkinsonism 5
malnutrition 5
CDT 5
iron deficiency 5
Infections 5
alcoholic hepatitis 5
stroke 5
viral hepatitis 5
endometritis 5
lipidosis 5
Best 5
ADH 5
anemia 5
heart failure 5
cerebral ischemia 5
West 4
mental retardation 4
Chagas 4
INS 4
periodontitis 4
AOA 4
zoonosis 4
hypoglycemic coma 4
primary biliary cirrhosis 4
temporal lobe epilepsy 4
hypertension 4
Yersinia 4
eczema 4
emotional stress 4
genetic disorder 4
dehydration 4
hyperlipidemia 4
paralytic ileus 4
SM1 4
mental retardation 4
tubular necrosis 4
glioma 4
Giardia infections 4
neurological disease 4
gastroenteritis 4
liver fibrosis 4
ASAT 4
amyotrophic lateral sclerosis 4
metabolic alkalosis 4
growth hormone deficiency 3
eosinophilia 3
insulinoma 3
metastases 3
Placenta 3
renal failure 3
coccidiosis 3
motor neuron disease 3
ileus 3
GHD 3
PCC 3
immunodeficiency 3
acute hepatitis 3
chronic schizophrenia 3
NHS 3
Dissociation 3
pancreatitis 3
progressive supranuclear palsy 3
chlorosis 3
status epilepticus 3
memory impairment 3
encephalomyelitis 3
dyspepsia 3
Reye 3
meningitis 3
Biotin deficiency 3
glucose intolerance 3
metabolic syndrome 3
parasitic disease 3
Beckwith-Wiedemann syndrome 3
cardiovascular disease 3
Poland 3
carcinogenesis 3
squamous cell carcinoma 3
glioblastoma 3
Brown 3
mastitis 3
gastrointestinal disease 3
uterus 3
gastric cancer 3
developmental delay 3
hypercholesterolemia 3
HIV 3
pheochromocytoma 3
arthritis 3
Still 3
more...
Symptom
diarrhea 79
starvation 62
seizures 31
ataxia 11
anorexia 8
cerebellar ataxia 7
hypothermia 7
exhaustion 6
pain 6
fatigue 5
abdominal pain 5
dystonia 5
hypotonia 5
weakness 4
anesthesia 4
hepatomegaly 3
vomiting 3
acidity 3
HSA 2
tremor 2
flushing 2
analgesia 2
Central pain 1
Mills 1
cyanosis 1
hyperoxia 1
general problem 1
nausea and vomiting 1
cough 1
shortness of breath 1
dyspnea 1
ataxic gait 1
memory loss 1
Upper back pain 1
dysarthria 1
bone pain 1
thinning 1
hepatosplenomegaly 1
anosmia 1
dark urine 1
cachexia 1
functional recovery 1
acute abdomen 1
collapse 1
Anoxia 1
stigma 1
headache 1
myoclonus 1
nasal congestion 1
ACHE 1
Drug
NADH 432
lysine 88
NH3 37
citric acid 35
FAD 27
Alanine 23
Gel 16
Leaf 12
pyridoxal phosphate 12
ascorbate 11
Giardiasis 8
Ethanol 8
Asn 7
lactose 6
CSF 6
vitamin E 6
CaCl2 5
Fructose 5
Glutamic acid 5
CaCl2 5
CaCl2 5
ABC 4
Glutathione 4
Cibacron Blue 4
Asparaginase 4
G418 4
caffeine 3
ROC 3
DNase I 3
Albumin 3
Glucagon 3
Galactose 3
Capsicum 2
Ammonium chloride 2
-deoxyadenosine 2
Guanidine 2
Nephron 2
Gabapentin 2
Vitamin A 2
Guanidine 2
Vitamin B 2
Clofibrate 2
Vitamin B12 2
THF 2
Vitamin E 2
Tween 40 2
Check 2
ALA 2
Scopolamine 2
Troglitazone 2
Fenbendazole 1
SiO2 1
EPA 1
VCR 1
Adenosine triphosphate 1
Omapatrilat 1
Zoledronic acid 1
AraC 1
Parkin 1
Frontal 1
Lifarizine 1
Sodium thiosulfate 1
ampicillin 1
niacin 1
Estrogens 1
IPM 1
GEO 1
Mycophenolic acid 1
Gastro 1
L-tyrosine 1
Horizon 1
Lactase 1
Kenyan 1
Monit 1
Dermatol 1
Fluorescein 1
ENT 1
NBT 1
Parkin 1
Flavin 1
IFN-gamma 1
Methscopolamine 1
Pegaspargase 1
Propidium 1
Atabrine 1
PCP 1
Abatacept 1
Streptokinase 1
THA 1
Ringer's solution 1
Glycerol 1
EE2 1
Phosphatidylserine 1
MIL 1
Perphenazine 1
PCB 1
TAC 1
Fluorescein 1
Arsenic trioxide 1
Salicylate 1
Butylamine 1
Cellulase 1
NAG 1
Duphalac 1
Cellulose acetate 1
DHT 1
Fraction 1
Fragment 1
TAT 1
Pyridoxal 1
Sodium valproate 1
Adenosine deaminase 1
PPA 1
PTH 1
Piracetam 1
Bidisomide 1
Nephron 1
Diurnal 1
DMAP 1
Glycyrrhiza 1
TiO2 1
DHT 1
Pentostam 1
Enzyme
glutamate dehydrogenase 4380
glutamate dehydrogenase 4349
glutamate dehydrogenase 4278
glutamine synthetase 595
aspartate aminotransferase 443
lactate dehydrogenase 328
alanine aminotransferase 328
glutamate synthase 286
glutamate synthase 283
glutamate synthase 275
malate dehydrogenase 221
glutamic dehydrogenase 214
glutaminase 173
alkaline phosphatase 142
isocitrate dehydrogenase 141
isocitrate dehydrogenase 135
succinate dehydrogenase 126
nitrate reductase 123
glucose-6-phosphate dehydrogenase 122
nitrate reductase 116
nitrate reductase 116
nitrate reductase 116
nitrate reductase 116
nitrate reductase 116
gamma-glutamyl transpeptidase 111
citrate synthase 87
phosphoenolpyruvate carboxykinase 81
alpha-ketoglutarate dehydrogenase 81
phosphoenolpyruvate carboxykinase 80
phosphoenolpyruvate carboxykinase 79
hexokinase 79
alcohol dehydrogenase 77
urease 73
catalase 72
pyruvate kinase 70
creatine kinase 68
urease 67
cytochrome oxidase 64
sorbitol dehydrogenase 64
ATPase 62
arginase 62
acid phosphatase 57
nitrite reductase 57
pyruvate dehydrogenase 57
nitrite reductase 56
nitrite reductase 56
diaphorase 54
glucokinase 52
glyceraldehyde-3-phosphate dehydrogenase 47
acetylcholinesterase 45
alanine dehydrogenase 44
pyruvate carboxylase 43
glyceraldehyde-3-phosphate dehydrogenase 43
trypsin 43
superoxide dismutase 42
glutamate decarboxylase 42
CPR 41
phosphofructokinase 41
glucose-6-phosphatase 41
monoamine oxidase 39
glycerol-3-phosphate dehydrogenase 38
glycerol-3-phosphate dehydrogenase 37
glyceraldehyde-3-phosphate dehydrogenase 37
AMP deaminase 37
glyceraldehyde-3-phosphate dehydrogenase 36
pyruvate dehydrogenase 34
pyruvate dehydrogenase 34
glyceraldehyde-3-phosphate dehydrogenase 34
cholinesterase 34
6-phosphogluconate dehydrogenase 33
adenosine deaminase 33
aldolase 33
6-phosphogluconate dehydrogenase 33
beta-hydroxybutyrate dehydrogenase 32
peroxidase 31
phosphoglucose isomerase 31
fumarase 30
ornithine transcarbamylase 26
glutathione reductase 24
aconitase 23
phosphoenolpyruvate carboxylase 23
ornithine aminotransferase 22
asparagine synthetase 22
glutathione S-transferase 22
succinic dehydrogenase 22
aldehyde dehydrogenase 21
AST 21
aldehyde dehydrogenase 21
aldehyde dehydrogenase 20
aldehyde dehydrogenase 20
aldehyde dehydrogenase 20
diaphorase 19
NADPH-diaphorase 19
CPS 18
adenylate kinase 18
collagenase 18
nitrogenase 18
GABA transaminase 18
leucine aminopeptidase 17
isocitrate lyase 17
ATP synthase 17
histidase 17
adenosine deaminase 16
branched-chain aminotransferase 16
tyrosine aminotransferase 16
lipase 16
lysozyme 16
phosphorylase 16
complex I 16
chymotrypsin 15
beta-glucuronidase 15
asparaginase 15
glutathione peroxidase 15
RNA polymerase 15
enolase 15
beta-galactosidase 14
proline oxidase 14
5'-nucleotidase 14
fructose 1,6-bisphosphatase 14
3-hydroxyacyl-CoA dehydrogenase 14
NQO1 13
3-hydroxyacyl-CoA dehydrogenase 13
carbamoylphosphate synthetase 13
phosphoglucomutase 13
ACS 13
leucine dehydrogenase 13
carbonic anhydrase 12
MDH 10
MDH 10
aspartase 10
AMP-activated protein kinase 10
glucose dehydrogenase 9
pyruvate decarboxylase 9
caspase-3 9
AMPK 9
alpha-glucosidase 9
xanthine oxidase 9
hydrogenase 9
protein kinase 9
RNase 9
hydrogenase 9
PHD 9
transhydrogenase 8
mitogen-activated protein kinase 8
invertase 8
demethylase 8
uricase 8
argininosuccinate synthetase 8
NADPH oxidase 8
lactic acid dehydrogenase 8
formate dehydrogenase 8
hexosaminidase 8
deaminase 8
proline dehydrogenase 7
triose-phosphate isomerase 7
UDP-glucuronosyltransferase 7
formate dehydrogenase 7
alpha-amylase 7
luciferase 7
xanthine dehydrogenase 7
more...
Compound
glutamate 1280
nitrogen 608
2-oxoglutarate 603
ammonia 600
glutamine 580
NAD 541
NADP 501
glucose 483
ammonium 476
NAD 432
NADH 432
phosphate 381
Dec 308
alanine 301
NADPH 285
NADPH 279
urea 265
Glutamate 245
DNA 239
ADP 224
ATP 223
ADP 218
ADP 216
Clin 205
NH2 162
leucine 157
GTP 155
nitrate 153
water 149
nicotinamide 147
oxygen 130
sodium 119
methionine 117
calcium 111
arginine 111
proline 109
lysine 102
glutamic acid 98
acetate 94
ethanol 79
potassium 77
salt 74
ornithine 73
ornithine 73
ornithine 73
ornithine 73
ornithine 73
sulfate 70
alcohol dehydrogenase 68
CO2 63
cysteine 62
His 60
Glutamine 60
hydrogen 60
asparagine 56
Asp 55
serine 53
GABA 52
creatinine 52
GABA 52
L-leucine 50
CoA 49
AMP 49
zinc 46
TCA 45
Phe 45
galactose 44
tyrosine 42
SDS 42
tryptophan 41
tryptophan 41
iron 41
glycerol 40
valine 40
tryptophan 38
tryptophan 38
Gly 35
aspartic acid 34
Ile 33
copper 31
pentose 30
pentose 30
pentose 30
pentose 30
isocitrate 29
isoleucine 29
oxalacetate 29
gamma-aminobutyric acid 29
isoleucine 28
FAD 28
Leucine 27
phosphorus 26
GSH 26
GSH 26
acetyl-CoA 26
aspartic acid 25
aspartic acid 25
aspartic acid 25
aldehyde 24
PEG 24
pyridine 24
Mg2+ 23
threonine 23
Alanine 23
NO3 22
Lactate 22
guanidine 22
bromide 21
cadmium 20
DEAE 20
heptane 20
Insulin 18
norvaline 18
acrylamide 18
cyanide 18
methanol 18
norvaline 18
glucose-6-phosphate 18
alpha-ketoisocaproate 17
PEG 17
Triton X-100 16
acetaldehyde 16
acetic acid 16
GPT 16
EDTA 15
EDTA 15
Nitrate 15
Tris 15
cAMP 15
hydroxylamine 14
CCl4 14
palmitoyl-CoA 14
HCl 14
Pyruvate 14
hydroxylamine 14
Optimal 13
carbamyl phosphate 13
adenylate 12
Tris 12
norleucine 12
hydroxyglutarate 12
alloxan 12
norleucine 12
succinic acid 12
butyric acid 11
ubiquinone 11
hexose 11
butyric acid 11
hexose 11
hexose 11
sodium chloride 11
butyric acid 11
selenium 11
hexose 11
TOF 10
H2O2 10
nitric oxide 10
GDP 10
dicarboxylic acid 10
acetone 10
more...