Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.4.1.2 (glutamate dehydrogenase)
 4,380 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Glutamate, dehydrogenase activity and its temperature dependence were studied in the rat brain at moderate (30 degrees C) and deep (20 degrees C) hypothermia. Depending on the grade and duration, hypothermia led to an increase in the enzyme activity at all the test temperatures of incubation. It is assumed that an increase in brain glutamate dehydrogenase activity at low body temperatures favours high level of the neurotransmitter glutamate to realize synaptic transmission, which may be regarded as adaptation reaction.
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PMID:[Effect of hypothermia on glutamate dehydrogenase activity of the brain]. 717 20