Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.4.1.2 (
glutamate dehydrogenase
)
4,380
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Recently developed tests that measure levels of alpha-amino-n-butyric acid (AANB) and serum
glutamic dehydrogenase
(
GDH
) may improve screening for early detection of
heavy drinking
and liver injury, respectively. With these tests, a "three-level" approach to the problem is now possible: (1) detection of
heavy drinking
on the basis of a biochemical marker (such as AANB); (2) detection of liver injury (necrosis and inflammation) on the basis of serum liver tests (such as
GDH
); and (3) detection of alcoholics in whom cirrhosis is prone to develop by the screening of liver biopsy specimens for precirrhotic lesions (such as pericentral sclerosis).
...
PMID:Alcoholism and alcoholic liver injury: new diagnostic and prognostic tests. 58 Aug 76
