Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.4.1.2 (
glutamate dehydrogenase
)
4,380
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Sublethal doses of
typhoid
endotoxin distinctly increased the activities of
glutamate dehydrogenase
and histidine ammonium lyase in liver tissue of mice within 3 hrs and the tyrosine transaminase activity within 6 hrs after a single intraperitoneal administration. Within 24 hrs normalzation of these enzyme activities and a decrease in the urocaninase activity were observed in liver tissue. Lipid A, obtained from the endotoxin, activated
glutamate dehydrogenase
and histidine ammonium lyase, inhibited urocaninase but did not affect the tyrosine transaminase activity. Lipid B, isolated by a non-hydrolytic method, showed even wore distinct capacity to activate
glutamate dehydrogenase
and histidine ammonium lyase, but did not alter the activities of tyrosine transaminase and urocaninase in liver tissue.
...
PMID:[The effect of lipids from typhoid endotoxin on the activity of some liver enzymes]. 0 21
Forty eight hours after the immunization with vaccines containing antigenic complexes of
typhoid
-paratyphoid and dysentery bacteria (0.65--1 mg of the antigens per vaccination dose) some of the persons vaccinated displayed an increase in the leukocyte count chiefly on account of the neutrophil forms and monocytes, a moderate elevation of bilirubin, asaraginamino-transferase and
glutamic dehydrogenase
in the serum; there was also some reduction of serum cholesterol, the appearance of cylinders and of protein traces in the urine, as well as ECG changes. The noted changes were of short duration and were not recorded in later examinations. The persons vaccinated presented no complains 24 hours, 2, 3, and 9 days after the vaccination and completely retained their working capacity.
...
PMID:[Findings concerning characteristics of responses to administration of vaccines containing antigenic complexes of enteric bacteria and tetanus toxoid]. 82 56
